Posttranscriptional silencing of the lncRNA MALAT1 by miR-217 inhibits the epithelial-mesenchymal transition via enhancer of zeste homolog 2 in the malignant transformation of HBE cells induced by cigarette smoke extract

Toxicology and Applied Pharmacology

Volumn 289, Issue 2, 2015, Pages 276-285

  Lu, Lu ^a,b   Luo, Fei ^a,b   Liu, Yi ^a,b   Liu, Xinlu ^a,b   Shi, Le ^a,b   Lu, Xiaolin ^a,b   Liu, Qizhan ^a,b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Nanjing Medical University   (China)

Author keywords

Cigarette smoke extract (CSE); Epithelial mesenchymal transition (EMT); LncRNAs; MiRNAs

Indexed keywords

ARGONAUTE 2 PROTEIN; CIGARETTE SMOKE; METASTASIS ASSOCIATED IN ADENOCARCINOMA TRANSCRIPT 1; MICRORNA; MICRORNA 101; MICRORNA 125B; MICRORNA 217; MICRORNA 9; NERVE CELL ADHESION MOLECULE; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG; UNTRANSLATED RNA; UVOMORULIN; VIMENTIN; EZH2 PROTEIN, HUMAN; HISTONE; HISTONE DEMETHYLASE; KDM1A PROTEIN, HUMAN; LONG UNTRANSLATED RNA; MALAT1 LONG NON-CODING RNA, HUMAN; MIRN217 MICRORNA, HUMAN; POLYCOMB REPRESSIVE COMPLEX 2; SMOKE;

ARTICLE; BRONCHUS MUCOSA; CARCINOGENESIS; CELL LYSATE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; LUNG CANCER; MALIGNANT TRANSFORMATION; POSTTRANSCRIPTIONAL GENE SILENCING; ADVERSE EFFECTS; BRONCHUS; CELL TRANSFORMATION; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; LUNG NEOPLASMS; METABOLISM; PATHOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMOKE; SMOKING; TIME FACTOR; TRANSFORMED CELL LINE;

BRONCHI; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE DEMETHYLASES; HISTONES; HUMANS; LUNG NEOPLASMS; MICRORNAS; POLYCOMB REPRESSIVE COMPLEX 2; RNA INTERFERENCE; RNA, LONG NONCODING; SIGNAL TRANSDUCTION; SMOKE; SMOKING; TIME FACTORS; TRANSFECTION;

EID: 84949313435     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.09.016     Document Type: Article

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