Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 49, 2015, Pages 15148-15153

  Bersani, Francesca ^a   Lee, Eunjung ^b,c   Kharchenko, Peter V ^b,d   Xu, Andrew W ^b   Liu, Mingzhu ^a,e   Xega, Kristina ^a   MacKenzie, Olivia C ^a   Brannigan, Brian W ^a   Wittner, Ben S ^a   Jung, Hyunchul ^f   Ramaswamy, Sridhar ^a,g   Park, Peter J ^b,c,d   Maheswaran, Shyamala ^a,g   Ting, David T ^a,g   Haber, Daniel A ^a,e,g  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Harvard Medical School Center for Biomedical Informatics   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^f Samsung Medical Center   (South Korea)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Cancer; Repeats; Reverse transcription; Satellites

Indexed keywords

COMPLEMENTARY DNA; RNA; SATELLITE DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; COLON CANCER; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA RNA HYBRIDIZATION; DNA SEQUENCE; GENE LOCUS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE REPEAT; OVERALL SURVIVAL; PERICENTROMERIC SATELLITE REPEAT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; TUMOR XENOGRAFT; WHOLE GENOME SEQUENCING; CENTROMERE; COLORECTAL TUMOR; GENETICS; NEOPLASM; NUCLEIC ACID HYBRIDIZATION; PATHOLOGY;

CENTROMERE; COLORECTAL NEOPLASMS; DNA, SATELLITE; HUMANS; NEOPLASMS; NUCLEIC ACID HYBRIDIZATION; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA;

EID: 84949289216     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1518008112     Document Type: Article

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