Identification of Hic-5 as a novel scaffold for the MKK4/p54 JNK pathway in the development of abdominal aortic aneurysms

Journal of the American Heart Association

Volumn 3, Issue 3, 2014, Pages

  Lei, Xiao Feng ^a   Kim Kaneyama, Joo Ri ^a   Arita Okubo, Shigeko ^a   Offermanns, Stefan ^b   Itabe, Hiroyuki ^a   Miyazaki, Takuro ^a   Miyazaki, Akira ^a  

^a SHOWA UNIVERSITY   (Japan)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

Aneurysm; Hic 5; JNK signaling scaffold protein; Smooth muscle

Indexed keywords

GELATINASE A; INTERSTITIAL COLLAGENASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN P54; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; ANGIOTENSIN II; CYTOSKELETON PROTEIN; DNA BINDING PROTEIN; LIM PROTEIN; MEMBRANE PROTEIN; P112 PROTEIN, RAT; PHOSPHOPROTEIN; TGFB1I1 PROTEIN, MOUSE;

ABDOMINAL AORTA ANEURYSM; ANEURYSM RUPTURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL WALL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVATION; ENZYME INHIBITION; GENE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; HIC 5 GENE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; ABDOMINAL AORTA; ANIMAL; AORTIC ANEURYSM, ABDOMINAL; DISEASE MODEL; DRUG EFFECTS; KNOCKOUT MOUSE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANGIOTENSIN II; ANIMALS; AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; LIM DOMAIN PROTEINS; MALE; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE, KNOCKOUT; PHOSPHOPROTEINS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84939461863     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.113.000747     Document Type: Article

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