Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: Implication in pulmonary hypertension

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 308, Issue 3, 2015, Pages L287-L300

  Chettimada, Sukrutha ^a   Gupte, Rakhee ^a   Rawat, Dhwajbahadur ^a   Gebb, Sarah A ^a   McMurtry, Ivan F ^b   Gupte, Sachin A ^a,b  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Cell cycle; HIF 1 ; KLF; Myocardin; NADPH; Reactive oxygen species; Redox; SM22 ; Smooth muscle phenotype; Sp1

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN A; GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HISTONE H3; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MYOCARDIN; PRASTERONE; TRANSCRIPTION FACTOR SP1; TRANSGELIN; HIF1A PROTEIN, RAT; NUCLEAR PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL PROLIFERATION; ENZYME ACTIVITY; GLUCOSE METABOLISM; HYPOXIA; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PHENOTYPE; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; SMOOTH MUSCLE FIBER; ANIMAL; CELL HYPOXIA; ENZYME INDUCTION; ENZYMOLOGY; GENE EXPRESSION; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; PATHOLOGY; PROTEIN SYNTHESIS; UPREGULATION;

ANIMALS; CELL CYCLE PROTEINS; CELL HYPOXIA; CELL PROLIFERATION; ENZYME INDUCTION; GENE EXPRESSION; GLUCOSEPHOSPHATE DEHYDROGENASE; HEK293 CELLS; HUMANS; HYDROGEN PEROXIDE; HYPERTENSION, PULMONARY; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MYOCYTES, SMOOTH MUSCLE; NUCLEAR PROTEINS; PROTEIN BIOSYNTHESIS; PULMONARY ARTERY; RATS; SP1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; UP-REGULATION;

EID: 84949126519     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00229.2014     Document Type: Article

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