Glc-6-PD and PKG contribute to hypoxia-induced decrease in smooth muscle cell contractile phenotype proteins in pulmonary artery

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 303, Issue 1, 2012, Pages

  Chettimada, Sukrutha ^a   Rawat, Dhwajbahadur K ^a   Dey, Nupur ^b   Kobelja, Robert ^a   Simms, Zachary ^a   Wolin, Michael S ^c   Lincoln, Thomas M ^b   Gupte, Sachin A ^a  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^c NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Cell phenotype; Confocal microscopy; Nadph; Passive tension; Pentose phosphate pathway; Pressure overload; Sm22 ; Smooth muscle; Stretch

Indexed keywords

CYCLIC GMP DEPENDENT PROTEIN KINASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; MYOSIN HEAVY CHAIN; TRANSGELIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COW; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HYPOXIA; LUNG VASOCONSTRICTION; MUSCLE CONTRACTILITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; SMOOTH MUSCLE FIBER;

ANIMALS; BIOLOGICAL MARKERS; CATTLE; CELL HYPOXIA; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; GLUCOSEPHOSPHATE DEHYDROGENASE; HYPERTENSION, PULMONARY; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; MYOSIN HEAVY CHAINS; PHENOTYPE; PHOSPHORYLATION; PULMONARY ARTERY; VASOCONSTRICTION;

EID: 84863423773     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00002.2012     Document Type: Article

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