메뉴 건너뛰기




Volumn 77, Issue , 2016, Pages 189-195

Interleukin 4 inhibition as a potential therapeutic in pemphigus

Author keywords

Anti cytokine therapy; Autoimmune disease; Interleukin 4; Pemphigus

Indexed keywords

ACETYLSALICYLIC ACID; DESMOGLEIN 1; DESMOGLEIN 3; DUPILUMAB; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G4; INTERLEUKIN 4; RITUXIMAB; IL4 PROTEIN, HUMAN; IMMUNOGLOBULIN G; INTERLEUKIN 4 RECEPTOR; MONOCLONAL ANTIBODY;

EID: 84949105952     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2015.09.017     Document Type: Article
Times cited : (54)

References (106)
  • 3
    • 54549103162 scopus 로고    scopus 로고
    • Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor α-chain expression
    • Liao W., Schones D.E., Oh J., Cui Y., Cui K., Roh T.-Y., et al. Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor α-chain expression. Nat. Immunol. 2008, 9:1288-1296.
    • (2008) Nat. Immunol. , vol.9 , pp. 1288-1296
    • Liao, W.1    Schones, D.E.2    Oh, J.3    Cui, Y.4    Cui, K.5    Roh, T.-Y.6
  • 4
    • 46949111064 scopus 로고    scopus 로고
    • Control of IL-4 expression in T helper 1 and 2 cells
    • Gilmour J., Lavender P. Control of IL-4 expression in T helper 1 and 2 cells. Immunology 2008, 124:437-444.
    • (2008) Immunology , vol.124 , pp. 437-444
    • Gilmour, J.1    Lavender, P.2
  • 7
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage
    • Steinman L. A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage. Nat. Med. 2007, 13:139-145.
    • (2007) Nat. Med. , vol.13 , pp. 139-145
    • Steinman, L.1
  • 8
    • 32644440459 scopus 로고    scopus 로고
    • Pro-and anti-inflammatory effects of IL-4: from studies in mice to therapy of autoimmune diseases in humans
    • Springer
    • Biedermann T., Röcken M. Pro-and anti-inflammatory effects of IL-4: from studies in mice to therapy of autoimmune diseases in humans. Animal Models of T Cell-Mediated Skin Diseases 2005, 235-242. Springer.
    • (2005) Animal Models of T Cell-Mediated Skin Diseases , pp. 235-242
    • Biedermann, T.1    Röcken, M.2
  • 9
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • Swain S.L., Weinberg A.D., English M., Huston G. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 1990, 145:3796-3806.
    • (1990) J. Immunol. , vol.145 , pp. 3796-3806
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 10
    • 0025082313 scopus 로고
    • Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
    • Le Gros G., Ben-Sasson S.Z., Seder R., Finkelman F., Paul W. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J. Exp. Med. 1990, 172:921-929.
    • (1990) J. Exp. Med. , vol.172 , pp. 921-929
    • Le Gros, G.1    Ben-Sasson, S.Z.2    Seder, R.3    Finkelman, F.4    Paul, W.5
  • 11
    • 0026648380 scopus 로고
    • Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system
    • Hsieh C.-S., Heimberger A.B., Gold J.S., O'Garra A., Murphy K.M. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc. Natl. Acad. Sci. 1992, 89:6065-6069.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 6065-6069
    • Hsieh, C.-S.1    Heimberger, A.B.2    Gold, J.S.3    O'Garra, A.4    Murphy, K.M.5
  • 12
    • 0026712313 scopus 로고
    • The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice
    • Seder R.A., Paul W.E., Davis M.M., de St Groth B.F. The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice. J. Exp. Med. 1992, 176:1091-1098.
    • (1992) J. Exp. Med. , vol.176 , pp. 1091-1098
    • Seder, R.A.1    Paul, W.E.2    Davis, M.M.3    de St Groth, B.F.4
  • 13
    • 0028577516 scopus 로고
    • Acquisition of lymphokine-producing phenotype by CD4+ T cells
    • Seder R.A. Acquisition of lymphokine-producing phenotype by CD4+ T cells. J. Allergy Clin. Immunol. 1994, 94:1195-1202.
    • (1994) J. Allergy Clin. Immunol. , vol.94 , pp. 1195-1202
    • Seder, R.A.1
  • 14
    • 84863393256 scopus 로고    scopus 로고
    • Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V
    • Vijayanand P., Seumois G., Simpson L.J., Abdul-Wajid S., Baumjohann D., Panduro M., et al. Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V. Immunity 2012, 36:175-187.
    • (2012) Immunity , vol.36 , pp. 175-187
    • Vijayanand, P.1    Seumois, G.2    Simpson, L.J.3    Abdul-Wajid, S.4    Baumjohann, D.5    Panduro, M.6
  • 15
    • 0041917266 scopus 로고    scopus 로고
    • Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease
    • Kidd P. Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease. Altern. Med. Rev. 2003, 8:223-246.
    • (2003) Altern. Med. Rev. , vol.8 , pp. 223-246
    • Kidd, P.1
  • 16
    • 84864964981 scopus 로고    scopus 로고
    • Cytokine networks in Pemphigus vulgaris: an integrated viewpoint
    • Giordano C.N., Sinha A.A. Cytokine networks in Pemphigus vulgaris: an integrated viewpoint. Autoimmunity 2012, 45:427-439.
    • (2012) Autoimmunity , vol.45 , pp. 427-439
    • Giordano, C.N.1    Sinha, A.A.2
  • 20
    • 84949102468 scopus 로고    scopus 로고
    • Epidemiology of pemphigus in Hamedan (west of Iran): a 10 year retrospective study (1995-2004)
    • Yazdanfar A. Epidemiology of pemphigus in Hamedan (west of Iran): a 10 year retrospective study (1995-2004). Int. J. Pharm. 2010, 1:157-160.
    • (2010) Int. J. Pharm. , vol.1 , pp. 157-160
    • Yazdanfar, A.1
  • 21
    • 0031935628 scopus 로고    scopus 로고
    • Epidemiologic analysis and clinical course of 84 consecutive cases of pemphigus in eastern Sicily
    • Micali M., Musumeci M., Maria L., Nasca M., Rita M. Epidemiologic analysis and clinical course of 84 consecutive cases of pemphigus in eastern Sicily. Int. J. Dermatol. 1998, 37:197-200.
    • (1998) Int. J. Dermatol. , vol.37 , pp. 197-200
    • Micali, M.1    Musumeci, M.2    Maria, L.3    Nasca, M.4    Rita, M.5
  • 22
    • 85047693835 scopus 로고
    • Pemphigus: epidemiologic and survival characteristics of 59 patients, 1955-1973
    • Krain L.S. Pemphigus: epidemiologic and survival characteristics of 59 patients, 1955-1973. Arch. Dermatol. 1974, 110:862-865.
    • (1974) Arch. Dermatol. , vol.110 , pp. 862-865
    • Krain, L.S.1
  • 24
    • 0033004417 scopus 로고    scopus 로고
    • The clinical phenotype of pemphigus is defined by the anti-desmoglein autoantibody profile
    • Amagai M., Tsunoda K., Zillikens D., Nagai T., Nishikawa T. The clinical phenotype of pemphigus is defined by the anti-desmoglein autoantibody profile. J. Am. Acad. Dermatol. 1999, 40:167-170.
    • (1999) J. Am. Acad. Dermatol. , vol.40 , pp. 167-170
    • Amagai, M.1    Tsunoda, K.2    Zillikens, D.3    Nagai, T.4    Nishikawa, T.5
  • 25
    • 0025789652 scopus 로고
    • Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion
    • Amagai M., Klaus-Kovtun V., Stanley J.R. Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion. Cell 1991, 67:869-877.
    • (1991) Cell , vol.67 , pp. 869-877
    • Amagai, M.1    Klaus-Kovtun, V.2    Stanley, J.R.3
  • 26
    • 84860325758 scopus 로고    scopus 로고
    • Five Japanese cases of antidesmoglein 1 antibody-positive and antidesmoglein 3 antibody-negative pemphigus with oral lesions
    • Koga H., Ohyama B., Tsuruta D., Ishii N., Hamada T., Dainichi T., et al. Five Japanese cases of antidesmoglein 1 antibody-positive and antidesmoglein 3 antibody-negative pemphigus with oral lesions. Br. J. Dermatol. 2012, 166:976-980.
    • (2012) Br. J. Dermatol. , vol.166 , pp. 976-980
    • Koga, H.1    Ohyama, B.2    Tsuruta, D.3    Ishii, N.4    Hamada, T.5    Dainichi, T.6
  • 27
    • 0030990853 scopus 로고    scopus 로고
    • Nonsecretory IgA1 autoantibodies targeting desmosomal component desmoglein 3 in intraepidermal neutrophilic IgA dermatosis
    • Wang J., Kwon J., Ding X., Fairley J.A., Woodley D.T., Chan L.S. Nonsecretory IgA1 autoantibodies targeting desmosomal component desmoglein 3 in intraepidermal neutrophilic IgA dermatosis. Am. J. Pathol. 1997, 150:1901.
    • (1997) Am. J. Pathol. , vol.150 , pp. 1901
    • Wang, J.1    Kwon, J.2    Ding, X.3    Fairley, J.A.4    Woodley, D.T.5    Chan, L.S.6
  • 28
    • 0029884450 scopus 로고    scopus 로고
    • Studies of autoantigens recognized by IgA anti-keratinocyte cell surface antibodies
    • Hashimoto T., Ebihara T., Nishikawa T. Studies of autoantigens recognized by IgA anti-keratinocyte cell surface antibodies. J. Dermatol. Sci. 1996, 12:10-17.
    • (1996) J. Dermatol. Sci. , vol.12 , pp. 10-17
    • Hashimoto, T.1    Ebihara, T.2    Nishikawa, T.3
  • 32
    • 0028209673 scopus 로고
    • Correlation of subclasses of IgG with disease activity in pemphigus vulgaris
    • Bhol K., Mohimen A., Ahmed A. Correlation of subclasses of IgG with disease activity in pemphigus vulgaris. Dermatology 1994, 189:85-89.
    • (1994) Dermatology , vol.189 , pp. 85-89
    • Bhol, K.1    Mohimen, A.2    Ahmed, A.3
  • 33
    • 58049202056 scopus 로고    scopus 로고
    • Effect of intravenous immunoglobulin therapy on serum levels of IgG1 and IgG4 antidesmoglein 1 and antidesmoglein 3 antibodies in pemphigus vulgaris
    • Green M.G., Bystryn J.-C. Effect of intravenous immunoglobulin therapy on serum levels of IgG1 and IgG4 antidesmoglein 1 and antidesmoglein 3 antibodies in pemphigus vulgaris. Arch. Dermatol. 2008, 144:1621-1624.
    • (2008) Arch. Dermatol. , vol.144 , pp. 1621-1624
    • Green, M.G.1    Bystryn, J.-C.2
  • 34
    • 84867095467 scopus 로고    scopus 로고
    • Specific immunoglobulin isotypes correlate with disease activity, morphology, duration and HLA association in Pemphigus vulgaris
    • Dhandha M.M., Seiffert-Sinha K., Sinha A.A. Specific immunoglobulin isotypes correlate with disease activity, morphology, duration and HLA association in Pemphigus vulgaris. Autoimmunity 2012, 45:516-526.
    • (2012) Autoimmunity , vol.45 , pp. 516-526
    • Dhandha, M.M.1    Seiffert-Sinha, K.2    Sinha, A.A.3
  • 35
    • 84862261531 scopus 로고    scopus 로고
    • Cognate Th2-B cell interaction is essential for the autoantibody production in pemphigus vulgaris
    • Zhu H., Chen Y., Zhou Y., Wang Y., Zheng J., Pan M. Cognate Th2-B cell interaction is essential for the autoantibody production in pemphigus vulgaris. J. Clin. Immunol. 2012, 32:114-123.
    • (2012) J. Clin. Immunol. , vol.32 , pp. 114-123
    • Zhu, H.1    Chen, Y.2    Zhou, Y.3    Wang, Y.4    Zheng, J.5    Pan, M.6
  • 36
    • 1542619242 scopus 로고    scopus 로고
    • T cell recognition of desmoglein 3 peptides in patients with pemphigus vulgaris and healthy individuals
    • Veldman C.M., Gebhard K.L., Uter W., Wassmuth R., Grötzinger J., Schultz E., et al. T cell recognition of desmoglein 3 peptides in patients with pemphigus vulgaris and healthy individuals. J. Immunol. 2004, 172:3883-3892.
    • (2004) J. Immunol. , vol.172 , pp. 3883-3892
    • Veldman, C.M.1    Gebhard, K.L.2    Uter, W.3    Wassmuth, R.4    Grötzinger, J.5    Schultz, E.6
  • 37
    • 22144435872 scopus 로고    scopus 로고
    • Direct characterization of human T cells in pemphigus vulgaris reveals elevated autoantigen-specific Th2 activity in association with active disease
    • Rizzo C., Fotino M., Zhang Y., Chow S., Spizuoco A., Sinha A. Direct characterization of human T cells in pemphigus vulgaris reveals elevated autoantigen-specific Th2 activity in association with active disease. Clin. Exp. Dermatol. 2005, 30:535-540.
    • (2005) Clin. Exp. Dermatol. , vol.30 , pp. 535-540
    • Rizzo, C.1    Fotino, M.2    Zhang, Y.3    Chow, S.4    Spizuoco, A.5    Sinha, A.6
  • 39
    • 17144400762 scopus 로고    scopus 로고
    • T regulatory-1 cells induce IgG4 production by B cells: role of IL-10
    • Satoguina J.S., Weyand E., Larbi J., Hoerauf A. T regulatory-1 cells induce IgG4 production by B cells: role of IL-10. J. Immunol. 2005, 174:4718-4726.
    • (2005) J. Immunol. , vol.174 , pp. 4718-4726
    • Satoguina, J.S.1    Weyand, E.2    Larbi, J.3    Hoerauf, A.4
  • 41
    • 0023933655 scopus 로고
    • Differential regulation of IgG1 and IgE synthesis by interleukin 4
    • Snapper C., Finkelman F., Paul W. Differential regulation of IgG1 and IgE synthesis by interleukin 4. J. Exp. Med. 1988, 167:183-196.
    • (1988) J. Exp. Med. , vol.167 , pp. 183-196
    • Snapper, C.1    Finkelman, F.2    Paul, W.3
  • 42
    • 0023818704 scopus 로고
    • Regulation of IgG1 and IgE production by interleukin 4
    • Snapper C.M., Finkelman F.D., Paul W.E. Regulation of IgG1 and IgE production by interleukin 4. Immunol. Rev. 1988, 102:51-75.
    • (1988) Immunol. Rev. , vol.102 , pp. 51-75
    • Snapper, C.M.1    Finkelman, F.D.2    Paul, W.E.3
  • 43
    • 0023785192 scopus 로고
    • Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures
    • Lebman D.A., Coffman R.L. Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures. J. Exp. Med. 1988, 168:853-862.
    • (1988) J. Exp. Med. , vol.168 , pp. 853-862
    • Lebman, D.A.1    Coffman, R.L.2
  • 44
    • 0026036128 scopus 로고
    • Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones
    • Gascan H., Gauchat J.-F., Roncarolo M.-G., Yssel H., Spits H., de Vries J.E. Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones. J. Exp. Med. 1991, 173:747-750.
    • (1991) J. Exp. Med. , vol.173 , pp. 747-750
    • Gascan, H.1    Gauchat, J.-F.2    Roncarolo, M.-G.3    Yssel, H.4    Spits, H.5    de Vries, J.E.6
  • 45
    • 0025064092 scopus 로고
    • The inductive effect of interleukin-4 on IgG4 and IgE synthesis in human peripheral blood lymphocytes
    • Ishizaka A., Sakiyama Y., Nakanishi M., Tomizawa K., Oshika E., Kojima K., et al. The inductive effect of interleukin-4 on IgG4 and IgE synthesis in human peripheral blood lymphocytes. Clin. Exp. Immunol. 1990, 79:392-396.
    • (1990) Clin. Exp. Immunol. , vol.79 , pp. 392-396
    • Ishizaka, A.1    Sakiyama, Y.2    Nakanishi, M.3    Tomizawa, K.4    Oshika, E.5    Kojima, K.6
  • 46
    • 70350591149 scopus 로고    scopus 로고
    • Involvement of TH1/TH2 cytokines in the pathogenesis of autoimmune skin disease-pemphigus vulgaris
    • Satyam A., Khandpur S., Sharma V., Sharma A. Involvement of TH1/TH2 cytokines in the pathogenesis of autoimmune skin disease-pemphigus vulgaris. Immunol. Invest. 2009, 38:498-509.
    • (2009) Immunol. Invest. , vol.38 , pp. 498-509
    • Satyam, A.1    Khandpur, S.2    Sharma, V.3    Sharma, A.4
  • 47
  • 48
    • 0031028992 scopus 로고    scopus 로고
    • Development and characterization of desmoglein-3 specific T cells from patients with pemphigus vulgaris
    • Lin M.-S., Swartz S.J., Lopez A., Ding X., Fernandez-Vina M.A., Stastny P., et al. Development and characterization of desmoglein-3 specific T cells from patients with pemphigus vulgaris. J. Clin. Invest. 1997, 99:31.
    • (1997) J. Clin. Invest. , vol.99 , pp. 31
    • Lin, M.-S.1    Swartz, S.J.2    Lopez, A.3    Ding, X.4    Fernandez-Vina, M.A.5    Stastny, P.6
  • 49
    • 79960449183 scopus 로고    scopus 로고
    • Cytokine profiles in the sera of Egyptian patients with oral pemphigus vulgaris
    • Eid H., El-Gamal B. Cytokine profiles in the sera of Egyptian patients with oral pemphigus vulgaris. Braz. J. Oral Sci. 2011, 10:83-87.
    • (2011) Braz. J. Oral Sci. , vol.10 , pp. 83-87
    • Eid, H.1    El-Gamal, B.2
  • 51
    • 0034269007 scopus 로고    scopus 로고
    • Serum cytokines in patients with Brazilian pemphigus foliaceus (fogo selvagem)
    • Zeoti D., Figueiredo J., Chiossi M., Roselino A. Serum cytokines in patients with Brazilian pemphigus foliaceus (fogo selvagem). Braz. J. Med. Biol. Res. 2000, 33:1065-1068.
    • (2000) Braz. J. Med. Biol. Res. , vol.33 , pp. 1065-1068
    • Zeoti, D.1    Figueiredo, J.2    Chiossi, M.3    Roselino, A.4
  • 52
    • 0032983886 scopus 로고    scopus 로고
    • Characterization of skin cytokines in bullous pemphigoid and pemphigus vulgaris
    • Rico M., Benning C., Weingart E., Streilein R., Hali R. Characterization of skin cytokines in bullous pemphigoid and pemphigus vulgaris. Br. J. Dermatol. 1999, 140:1079-1086.
    • (1999) Br. J. Dermatol. , vol.140 , pp. 1079-1086
    • Rico, M.1    Benning, C.2    Weingart, E.3    Streilein, R.4    Hali, R.5
  • 53
    • 79952291528 scopus 로고    scopus 로고
    • Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases
    • 701-721.e70
    • Akdis M., Burgler S., Crameri R., Eiwegger T., Fujita H., Gomez E., et al. Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases. J. Allergy Clin. Immunol. 2011, 127. 701-721.e70.
    • (2011) J. Allergy Clin. Immunol. , vol.127
    • Akdis, M.1    Burgler, S.2    Crameri, R.3    Eiwegger, T.4    Fujita, H.5    Gomez, E.6
  • 54
    • 0027731604 scopus 로고
    • Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4
    • Kondo M., Takeshita T., Ishii N., Nakamura M., Watanabe S., K-i Arai., et al. Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4. Science 1993, 262:1874-1877.
    • (1993) Science , vol.262 , pp. 1874-1877
    • Kondo, M.1    Takeshita, T.2    Ishii, N.3    Nakamura, M.4    Watanabe, S.5    K-i, A.6
  • 55
    • 0027787877 scopus 로고
    • Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor
    • Russell S.M., Keegan A.D., Harada N., Nakamura Y., Noguchi M., Leland P., et al. Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor. Science 1993, 262:1880-1883.
    • (1993) Science , vol.262 , pp. 1880-1883
    • Russell, S.M.1    Keegan, A.D.2    Harada, N.3    Nakamura, Y.4    Noguchi, M.5    Leland, P.6
  • 56
    • 0028962572 scopus 로고
    • The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
    • Lin J.-X., Migone T.-S., Tseng M., Friedmann M., Weatherbee J.A., Zhou L., et al. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 1995, 2:331-339.
    • (1995) Immunity , vol.2 , pp. 331-339
    • Lin, J.-X.1    Migone, T.-S.2    Tseng, M.3    Friedmann, M.4    Weatherbee, J.A.5    Zhou, L.6
  • 57
    • 0033016764 scopus 로고    scopus 로고
    • Inhibition of IL-4-inducible gene expression in human monocytes by type I and type II interferons
    • Dickensheets H.L., Donnelly R.P. Inhibition of IL-4-inducible gene expression in human monocytes by type I and type II interferons. J. Leukoc. Biol. 1999, 65:307-312.
    • (1999) J. Leukoc. Biol. , vol.65 , pp. 307-312
    • Dickensheets, H.L.1    Donnelly, R.P.2
  • 58
    • 0038035229 scopus 로고    scopus 로고
    • Interleukin-4: a multifunctional cytokine
    • Zamorano J., Rivas M., Perez G. Interleukin-4: a multifunctional cytokine. Immunologia 2003, 22:215-224.
    • (2003) Immunologia , vol.22 , pp. 215-224
    • Zamorano, J.1    Rivas, M.2    Perez, G.3
  • 59
    • 0041374389 scopus 로고    scopus 로고
    • The function role of GATA-3 in Th1 and Th2 differentiation
    • Zhou M., Ouyang W. The function role of GATA-3 in Th1 and Th2 differentiation. Immunol. Res. 2003, 28:25-37.
    • (2003) Immunol. Res. , vol.28 , pp. 25-37
    • Zhou, M.1    Ouyang, W.2
  • 60
    • 0032538985 scopus 로고    scopus 로고
    • C-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and-independent mechanisms
    • Ho I.-C., Lo D., Glimcher L.H. C-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and-independent mechanisms. J. Exp. Med. 1998, 188:1859-1866.
    • (1998) J. Exp. Med. , vol.188 , pp. 1859-1866
    • Ho, I.-C.1    Lo, D.2    Glimcher, L.H.3
  • 61
    • 84862270948 scopus 로고    scopus 로고
    • Changes in the Th1: Th2 cytokine bias in pregnancy and the effects of the anti-inflammatory cyclopentenone prostaglandin 15-deoxy-prostaglandin
    • Sykes L., MacIntyre D.A., Yap X.J., Ponnampalam S., Teoh T.G., Bennett P.R. Changes in the Th1: Th2 cytokine bias in pregnancy and the effects of the anti-inflammatory cyclopentenone prostaglandin 15-deoxy-prostaglandin. Mediators Inflamm. 2012, 2012.
    • (2012) Mediators Inflamm. , vol.2012
    • Sykes, L.1    MacIntyre, D.A.2    Yap, X.J.3    Ponnampalam, S.4    Teoh, T.G.5    Bennett, P.R.6
  • 63
    • 70449418122 scopus 로고    scopus 로고
    • Pemphigus vulgaris in pregnancy: analysis of current data on the management and outcomes
    • Kardos M., Levine D., Gürcan H.M., Ahmed A.R. Pemphigus vulgaris in pregnancy: analysis of current data on the management and outcomes. Obstet. Gynecol. Surv. 2009, 64:739-749.
    • (2009) Obstet. Gynecol. Surv. , vol.64 , pp. 739-749
    • Kardos, M.1    Levine, D.2    Gürcan, H.M.3    Ahmed, A.R.4
  • 65
    • 84949099544 scopus 로고    scopus 로고
    • Action IPAI-LAIPAI-L
    • Action IPAI-LAIPAI-L, http://www.fda.gov/Drugs/DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/ApprovalApplications/TherapeuticBiologicApplications/ucm093327.htm.
  • 66
    • 84949087844 scopus 로고    scopus 로고
    • Information on Tumor Necrosis Factor (TNF) Blockers (marketed as Remicade E, Humira, Cimzia, and Simponi) (Information on Tumor Necrosis Factor (TNF) Blockers (marketed as Remicade, Enbrel, Humira, Cimzia, and Simponi)).
    • Information on Tumor Necrosis Factor (TNF) Blockers (marketed as Remicade E, Humira, Cimzia, and Simponi) (Information on Tumor Necrosis Factor (TNF) Blockers (marketed as Remicade, Enbrel, Humira, Cimzia, and Simponi)), http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm109340.htm.
  • 67
    • 84881110807 scopus 로고    scopus 로고
    • Cytokine inhibition as a strategy for treating systemic lupus erythematosus
    • Clark D.N., Markham J.L., Sloan C.S., Poole B.D. Cytokine inhibition as a strategy for treating systemic lupus erythematosus. Clin. Immunol. 2013, 148:335-343.
    • (2013) Clin. Immunol. , vol.148 , pp. 335-343
    • Clark, D.N.1    Markham, J.L.2    Sloan, C.S.3    Poole, B.D.4
  • 68
    • 84925297211 scopus 로고    scopus 로고
    • A multicentre randomized trial of the treatment of patients with pemphigus vulgaris with infliximab and prednisone compared with prednisone alone
    • Hall R., Fairley J., Woodley D., Werth V., Hannah D., Streilein R., et al. A multicentre randomized trial of the treatment of patients with pemphigus vulgaris with infliximab and prednisone compared with prednisone alone. Br. J. Dermatol. 2015, 172:760-768.
    • (2015) Br. J. Dermatol. , vol.172 , pp. 760-768
    • Hall, R.1    Fairley, J.2    Woodley, D.3    Werth, V.4    Hannah, D.5    Streilein, R.6
  • 69
    • 84925238472 scopus 로고    scopus 로고
    • To (anti-) TNF or not (anti-) TNF? That is the question in pemphigus
    • Sinha A. To (anti-) TNF or not (anti-) TNF? That is the question in pemphigus. Br. J. Dermatol. 2015, 172:564-565.
    • (2015) Br. J. Dermatol. , vol.172 , pp. 564-565
    • Sinha, A.1
  • 70
    • 84949086707 scopus 로고    scopus 로고
    • Level of IgG4 anti-desmoglein 3 antibodies correlates with disease activity in patients with pemphigus vulgaris
    • 1.1
    • José Antonio Delgado García, Carmen Pérez Robles, Juan José Mata Molanes, Laura Moreno Narro, Paula Arana Berganza, Level of IgG4 anti-desmoglein 3 antibodies correlates with disease activity in patients with pemphigus vulgaris, Autoimmun Infec. Dis. 1.1 (2005). doi:10.16966/aidoa.101.
    • (2005) Autoimmun Infec. Dis.
    • Delgado García, J.A.1    Robles, C.P.2    Mata Molanes, J.J.3    Narro, L.M.4    Berganza, P.A.5
  • 73
    • 0024349074 scopus 로고
    • Aspirin and thymosin increase interleukin-2 and interferon-γ production by human peripheral blood lymphocytes
    • Hsia J., Sarin N., Oliver J.H., Goldstein A.L. Aspirin and thymosin increase interleukin-2 and interferon-γ production by human peripheral blood lymphocytes. Immunopharmacology 1989, 17:167-173.
    • (1989) Immunopharmacology , vol.17 , pp. 167-173
    • Hsia, J.1    Sarin, N.2    Oliver, J.H.3    Goldstein, A.L.4
  • 74
    • 0036467550 scopus 로고    scopus 로고
    • Aspirin and salicylates inhibit the IL-4-and IL-13-induced activation of STAT6
    • Perez-G M., Melo M., Keegan A.D., Zamorano J. Aspirin and salicylates inhibit the IL-4-and IL-13-induced activation of STAT6. J. Immunol. 2002, 168:1428-1434.
    • (2002) J. Immunol. , vol.168 , pp. 1428-1434
    • Perez-G, M.1    Melo, M.2    Keegan, A.D.3    Zamorano, J.4
  • 75
    • 0025758896 scopus 로고
    • Interleukin-2 inhibits the interleukin-4-induced human IgE and IgG4 secretion in vivo
    • Spiegelberg H., Falkoff R., O'Connor R., Beck L. Interleukin-2 inhibits the interleukin-4-induced human IgE and IgG4 secretion in vivo. Clin. Exp. Immunol. 1991, 84:400.
    • (1991) Clin. Exp. Immunol. , vol.84 , pp. 400
    • Spiegelberg, H.1    Falkoff, R.2    O'Connor, R.3    Beck, L.4
  • 76
    • 84939949333 scopus 로고    scopus 로고
    • Study of T helper 1 and T helper 2 responses in pemphigus vulgaris patients receiving interferon alpha 2a injections in addition to a standard protocol therapy: a randomized controlled trial
    • El-Darouti M.A., Hegazy R.A., Hay R.M.A., El Hawary M.S., Tawdy A.M., Fawzy M.M., et al. Study of T helper 1 and T helper 2 responses in pemphigus vulgaris patients receiving interferon alpha 2a injections in addition to a standard protocol therapy: a randomized controlled trial. Arch. Dermatol. Res. 2015, 307:299-307.
    • (2015) Arch. Dermatol. Res. , vol.307 , pp. 299-307
    • El-Darouti, M.A.1    Hegazy, R.A.2    Hay, R.M.A.3    El Hawary, M.S.4    Tawdy, A.M.5    Fawzy, M.M.6
  • 77
    • 0034641533 scopus 로고    scopus 로고
    • Th1 and Th2 responses: what are they?
    • Berger A. Th1 and Th2 responses: what are they?. BMJ 2000, 321:424.
    • (2000) BMJ , vol.321 , pp. 424
    • Berger, A.1
  • 79
  • 83
    • 28744446703 scopus 로고    scopus 로고
    • Rituximab: a promising therapy in systemic lupus erythematosus
    • Thatayatikom A., White A.J. Rituximab: a promising therapy in systemic lupus erythematosus. Autoimmun. Rev. 2006, 5:18-24.
    • (2006) Autoimmun. Rev. , vol.5 , pp. 18-24
    • Thatayatikom, A.1    White, A.J.2
  • 85
    • 54949129325 scopus 로고    scopus 로고
    • Highly sensitive B cell analysis predicts response to rituximab therapy in rheumatoid arthritis
    • Dass S., Rawstron A.C., Vital E.M., Henshaw K., McGonagle D., Emery P. Highly sensitive B cell analysis predicts response to rituximab therapy in rheumatoid arthritis. Arthritis Rheum. 2008, 58:2993-2999.
    • (2008) Arthritis Rheum. , vol.58 , pp. 2993-2999
    • Dass, S.1    Rawstron, A.C.2    Vital, E.M.3    Henshaw, K.4    McGonagle, D.5    Emery, P.6
  • 86
    • 8744228329 scopus 로고    scopus 로고
    • Therapy of refractory pemphigus vulgaris with monoclonal anti-CD20 antibody (rituximab)
    • Morrison L.H. Therapy of refractory pemphigus vulgaris with monoclonal anti-CD20 antibody (rituximab). J. Am. Acad. Dermatol. 2004, 51:817-819.
    • (2004) J. Am. Acad. Dermatol. , vol.51 , pp. 817-819
    • Morrison, L.H.1
  • 87
    • 53349110013 scopus 로고    scopus 로고
    • Treatment of severe pemphigus foliaceus with rituximab
    • Fernando S.L., O'Connor K.S. Treatment of severe pemphigus foliaceus with rituximab. Med. J. Aust. 2008, 189:289-290.
    • (2008) Med. J. Aust. , vol.189 , pp. 289-290
    • Fernando, S.L.1    O'Connor, K.S.2
  • 92
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
    • Kaplan M.H., Schindler U., Smiley S.T., Grusby M.J. Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells. Immunity 1996, 4:313-319.
    • (1996) Immunity , vol.4 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 93
    • 0033427612 scopus 로고    scopus 로고
    • Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells
    • Kurata H., Lee H.J., O'Garra A., Arai N. Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells. Immunity 1999, 11:677-688.
    • (1999) Immunity , vol.11 , pp. 677-688
    • Kurata, H.1    Lee, H.J.2    O'Garra, A.3    Arai, N.4
  • 94
    • 0028943484 scopus 로고
    • Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat) 3 and Stat4
    • Jacobson N.G., Szabo S.J., Weber-Nordt R.M., Zhong Z., Schreiber R.D., Darnell J., et al. Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat) 3 and Stat4. J. Exp. Med. 1995, 181:1755-1762.
    • (1995) J. Exp. Med. , vol.181 , pp. 1755-1762
    • Jacobson, N.G.1    Szabo, S.J.2    Weber-Nordt, R.M.3    Zhong, Z.4    Schreiber, R.D.5    Darnell, J.6
  • 96
    • 84949108214 scopus 로고    scopus 로고
    • Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
    • Grusby M.J. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 1996, 382:11.
    • (1996) Nature , vol.382 , pp. 11
    • Grusby, M.J.1
  • 97
    • 0027199519 scopus 로고
    • Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo
    • Powrie F., Menon S., Coffman R.L. Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. Eur. J. Immunol. 1993, 23:2223-2229.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2223-2229
    • Powrie, F.1    Menon, S.2    Coffman, R.L.3
  • 98
    • 0031569531 scopus 로고    scopus 로고
    • Crossregulation between T helper cell (Th) 1 and Th2: inhibition of Th2 proliferation by IFN-gamma involves interference with IL-1
    • Oriss T.B., McCarthy S.A., Morel B.F., Campana M., Morel P.A. Crossregulation between T helper cell (Th) 1 and Th2: inhibition of Th2 proliferation by IFN-gamma involves interference with IL-1. J. Immunol. 1997, 158:3666-3672.
    • (1997) J. Immunol. , vol.158 , pp. 3666-3672
    • Oriss, T.B.1    McCarthy, S.A.2    Morel, B.F.3    Campana, M.4    Morel, P.A.5
  • 99
    • 0035742033 scopus 로고    scopus 로고
    • Pemphigus-paradigm of autoantibody-mediated autoimmunity
    • Hertl M., Veldman C. Pemphigus-paradigm of autoantibody-mediated autoimmunity. Skin Pharmacol. Physiol. 2001, 14:408-418.
    • (2001) Skin Pharmacol. Physiol. , vol.14 , pp. 408-418
    • Hertl, M.1    Veldman, C.2
  • 100
    • 33750291236 scopus 로고    scopus 로고
    • Treatment of pemphigus vulgaris with rituximab and intravenous immune globulin
    • Ahmed A.R., Spigelman Z., Cavacini L.A., Posner M.R. Treatment of pemphigus vulgaris with rituximab and intravenous immune globulin. N. Engl. J. Med. 2006, 355:1772-1779.
    • (2006) N. Engl. J. Med. , vol.355 , pp. 1772-1779
    • Ahmed, A.R.1    Spigelman, Z.2    Cavacini, L.A.3    Posner, M.R.4
  • 102
    • 33748333248 scopus 로고    scopus 로고
    • Anti-TNF-α antibody therapies in autoimmune diseases
    • Chatzantoni K., Mouzaki A. Anti-TNF-α antibody therapies in autoimmune diseases. Curr. Top. Med. Chem. 2006, 6:1707-1714.
    • (2006) Curr. Top. Med. Chem. , vol.6 , pp. 1707-1714
    • Chatzantoni, K.1    Mouzaki, A.2
  • 105
    • 0035178667 scopus 로고    scopus 로고
    • Serum levels of interleukins (IL)-4, IL-5, IL-13, and interferon-γ in acute asthma
    • Lee Y.C., Lee K.H., Lee H.B., Rhee Y.K. Serum levels of interleukins (IL)-4, IL-5, IL-13, and interferon-γ in acute asthma. J. Asthma 2001, 38:665-671.
    • (2001) J. Asthma , vol.38 , pp. 665-671
    • Lee, Y.C.1    Lee, K.H.2    Lee, H.B.3    Rhee, Y.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.