Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response

Human Molecular Genetics

Volumn 24, Issue 22, 2015, Pages 6515-6529

  Larroquette, Frédérique ^a   Seto, Lesley ^a   Gaub, Perrine L ^a   Kamal, Brishna ^a   Wallis, Deeann ^b   Larivière, Roxanne ^a   Vallée, Joanne ^c   Robitaille, Richard ^c   Tsuda, Hiroshi ^a  

^a MCGILL UNIVERSITY   (Canada)

^b TEXAS A AND M UNIVERSITY   (United States)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALRETICULIN; GLUCOSE REGULATED PROTEIN 78; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INITIATION FACTOR 2ALPHA; MESSENGER RNA; SYNAPTOBREVIN; UNCLASSIFIED DRUG; VESICLE ASSOCIATED MEMBRANE PROTEIN ASSOCIATED PROTEIN B; MEMBRANE PROTEIN; VAPB PROTEIN, HUMAN; VAPB PROTEIN, MOUSE; VESICULAR TRANSPORT PROTEIN;

ALLELE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL INCLUSION; CONTROLLED STUDY; CYTOPLASM; DOSE RESPONSE; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE MUTATION; HETEROZYGOSITY; HOMOLOGOUS RECOMBINATION; HOMOZYGOSITY; HUMAN; LOCOMOTION; MOTONEURON; MOTOR DYSFUNCTION; MOUSE; MUSCLE DENERVATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN HOMEOSTASIS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SOLEUS MUSCLE; UPREGULATION; ANIMAL; C57BL MOUSE; ENDOPLASMIC RETICULUM; GENE TARGETING; GENETICS; METABOLISM; MISSENSE MUTATION; MOTOR NEURON DISEASE; PATHOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; AUTOPHAGY; ENDOPLASMIC RETICULUM; GENE KNOCK-IN TECHNIQUES; HUMANS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR NEURON DISEASE; MOTOR NEURONS; MUTATION, MISSENSE; STRESS, PHYSIOLOGICAL; VESICULAR TRANSPORT PROTEINS;

EID: 84949035582     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv360     Document Type: Article

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