-
1
-
-
12344282783
-
Global burden of hypertension: Analysis of worldwide data
-
Kearney, P. M. et al. Global burden of hypertension: analysis of worldwide data. Lancet 365, 217-223 (2005).
-
(2005)
Lancet
, vol.365
, pp. 217-223
-
-
Kearney, P.M.1
-
2
-
-
34547615709
-
2007 Guidelines for the management of arterial hypertension: The task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
-
Mancia, G. et al. 2007 Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur. Heart J. 28, 1462-1536 (2007).
-
(2007)
Eur. Heart J.
, vol.28
, pp. 1462-1536
-
-
Mancia, G.1
-
3
-
-
36448950113
-
The burden of blood pressure-related disease: A neglected priority for global health
-
Perkovic, V., Huxley, R., Wu, Y., Prabhakaran, D. & MacMahon, S. The burden of blood pressure-related disease: a neglected priority for global health. Hypertension 50, 991-997 (2007).
-
(2007)
Hypertension
, vol.50
, pp. 991-997
-
-
Perkovic, V.1
Huxley, R.2
Wu, Y.3
Prabhakaran, D.4
MacMahon, S.5
-
4
-
-
84863869708
-
Genetic basis of blood pressure and hypertension
-
Padmanabhan, S., Newton-Cheh, C. & Dominiczak, A. F. Genetic basis of blood pressure and hypertension. Trends Genet. 28, 397-408 (2012).
-
(2012)
Trends Genet.
, vol.28
, pp. 397-408
-
-
Padmanabhan, S.1
Newton-Cheh, C.2
Dominiczak, A.F.3
-
5
-
-
80053907554
-
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
-
International Consortium for Blood Pressure Genome-Wide Association
-
International Consortium for Blood Pressure Genome-Wide Association StudiesEhret, G. B. et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 478, 103-109 (2011).
-
(2011)
Nature
, vol.478
, pp. 103-109
-
-
StudiesEhret, G.B.1
-
6
-
-
84858383447
-
Genetics of human cardiovascular disease
-
Kathiresan, S. & Srivastava, D. Genetics of human cardiovascular disease. Cell 148, 1242-1257 (2012).
-
(2012)
Cell
, vol.148
, pp. 1242-1257
-
-
Kathiresan, S.1
Srivastava, D.2
-
7
-
-
84904654600
-
Rare GATA5 sequence variants identified in individuals with bicuspid aortic valve
-
Bonachea, E. M. et al. Rare GATA5 sequence variants identified in individuals with bicuspid aortic valve. Pediatr. Res. 76, 211-216 (2014).
-
(2014)
Pediatr. Res.
, vol.76
, pp. 211-216
-
-
Bonachea, E.M.1
-
8
-
-
84862854537
-
Rare non-synonymous variations in the transcriptional activation domains of GATA5 in bicuspid aortic valve disease
-
Padang, R., Bagnall, R. D., Richmond, D. R., Bannon, P. G. & Semsarian, C. Rare non-synonymous variations in the transcriptional activation domains of GATA5 in bicuspid aortic valve disease. J. Mol. Cell. Cardiol. 53, 277-281 (2012).
-
(2012)
J. Mol. Cell. Cardiol.
, vol.53
, pp. 277-281
-
-
Padang, R.1
Bagnall, R.D.2
Richmond, D.R.3
Bannon, P.G.4
Semsarian, C.5
-
9
-
-
79959913398
-
Loss of Gata5 in mice leads to bicuspid aortic valve
-
Laforest, B., Andelfinger, G. & Nemer, M. Loss of Gata5 in mice leads to bicuspid aortic valve. J. Clin. Invest. 121, 2876-2887 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2876-2887
-
-
Laforest, B.1
Andelfinger, G.2
Nemer, M.3
-
10
-
-
3142566471
-
GATA transcription factors in the developing and adult heart
-
Pikkarainen, S., Tokola, H., Kerkela, R. & Ruskoaho, H. GATA transcription factors in the developing and adult heart. Cardiovasc. Res. 63, 196-207 (2004).
-
(2004)
Cardiovasc. Res.
, vol.63
, pp. 196-207
-
-
Pikkarainen, S.1
Tokola, H.2
Kerkela, R.3
Ruskoaho, H.4
-
11
-
-
0031105607
-
GATA-5: A transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development
-
Morrisey, E. E., Ip, H. S., Tang, Z., Lu, M. M. & Parmacek, M. S. GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development. Dev. Biol. 183, 21-36 (1997).
-
(1997)
Dev. Biol.
, vol.183
, pp. 21-36
-
-
Morrisey, E.E.1
Ip, H.S.2
Tang, Z.3
Lu, M.M.4
Parmacek, M.S.5
-
12
-
-
0037330475
-
Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6
-
Nemer, G. & Nemer, M. Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6. Dev. Biol. 254, 131-148 (2003).
-
(2003)
Dev. Biol.
, vol.254
, pp. 131-148
-
-
Nemer, G.1
Nemer, M.2
-
13
-
-
0036713123
-
Cooperative interaction between GATA5 and NF-ATc regulates endothelial-endocardial differentiation of cardiogenic cells
-
Nemer, G. & Nemer, M. Cooperative interaction between GATA5 and NF-ATc regulates endothelial-endocardial differentiation of cardiogenic cells. Development 129, 4045-4055 (2002).
-
(2002)
Development
, vol.129
, pp. 4045-4055
-
-
Nemer, G.1
Nemer, M.2
-
14
-
-
84873868258
-
Signaling effectors underlying pathologic growth and remodeling of the heart
-
van Berlo, J. H., Maillet, M. & Molkentin, J. D. Signaling effectors underlying pathologic growth and remodeling of the heart. J. Clin. Invest. 123, 37-45 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 37-45
-
-
Van Berlo, J.H.1
Maillet, M.2
Molkentin, J.D.3
-
15
-
-
84867745191
-
Prevalence of electrocardiographic left ventricular hypertrophy in human hypertension: An updated review
-
Cuspidi, C. et al. Prevalence of electrocardiographic left ventricular hypertrophy in human hypertension: an updated review. J. Hypertens. 30, 2066-2073 (2012).
-
(2012)
J. Hypertens.
, vol.30
, pp. 2066-2073
-
-
Cuspidi, C.1
-
16
-
-
84893549987
-
2014 evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8)
-
James, P. A. et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 311, 507-520 (2014).
-
(2014)
JAMA
, vol.311
, pp. 507-520
-
-
James, P.A.1
-
17
-
-
68549118943
-
Thiazide effects and adverse effects: Insights from molecular genetics
-
Ellison, D. H. & Loffing, J. Thiazide effects and adverse effects: insights from molecular genetics. Hypertension 54, 196-202 (2009).
-
(2009)
Hypertension
, vol.54
, pp. 196-202
-
-
Ellison, D.H.1
Loffing, J.2
-
18
-
-
81255195551
-
Under pressure: The search for the essential mechanisms of hypertension
-
Coffman, T. M. Under pressure: the search for the essential mechanisms of hypertension. Nat. Med. 17, 1402-1409 (2011).
-
(2011)
Nat. Med.
, vol.17
, pp. 1402-1409
-
-
Coffman, T.M.1
-
19
-
-
77949868470
-
T lymphocytes mediate hypertension and kidney damage in Dahl salt-sensitive rats
-
De Miguel, C., Das, S., Lund, H. & Mattson, D. L. T lymphocytes mediate hypertension and kidney damage in Dahl salt-sensitive rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 298, R1136-R1142 (2010).
-
(2010)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.298
, pp. R1136-R1142
-
-
De Miguel, C.1
Das, S.2
Lund, H.3
Mattson, D.L.4
-
20
-
-
77955285843
-
Molecular mechanisms underlying the activation of eNOS
-
Fleming, I. Molecular mechanisms underlying the activation of eNOS. Pflugers Arch. 459, 793-806 (2010).
-
(2010)
Pflugers Arch.
, vol.459
, pp. 793-806
-
-
Fleming, I.1
-
21
-
-
84947612492
-
The critical role of Akt in cardiovascular function
-
Abeyrathna, P. & Su, Y. The critical role of Akt in cardiovascular function. Vascul. Pharmacol. doi: 10.1016/j.vph.2015.05.008 (2015).
-
(2015)
Vascul. Pharmacol.
-
-
Abeyrathna, P.1
Su, Y.2
-
22
-
-
79957890939
-
Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets
-
Drummond, G. R., Selemidis, S., Griendling, K. K. & Sobey, C. G. Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat. Rev. Drug Discov. 10, 453-471 (2011).
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, pp. 453-471
-
-
Drummond, G.R.1
Selemidis, S.2
Griendling, K.K.3
Sobey, C.G.4
-
23
-
-
77955438579
-
Gene dosage of the common variant 9p21 predicts severity of coronary artery disease
-
Dandona, S. et al. Gene dosage of the common variant 9p21 predicts severity of coronary artery disease. J. Am. Coll. Cardiol. 56, 479-486 (2010).
-
(2010)
J. Am. Coll. Cardiol.
, vol.56
, pp. 479-486
-
-
Dandona, S.1
-
24
-
-
34548420712
-
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): A randomised controlled trial
-
Patel, A. et al. Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet 370, 829-840 (2007).
-
(2007)
Lancet
, vol.370
, pp. 829-840
-
-
Patel, A.1
-
25
-
-
66249120367
-
Human Splicing Finder: An online bioinformatics tool to predict splicing signals
-
Desmet, F. O. et al. Human Splicing Finder: an online bioinformatics tool to predict splicing signals. Nucleic Acids Res. 37, e67 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. e67
-
-
Desmet, F.O.1
-
26
-
-
0029843035
-
Defective L-arginine-nitric oxide pathway in offspring of essential hypertensive patients
-
Taddei, S. et al. Defective L-arginine-nitric oxide pathway in offspring of essential hypertensive patients. Circulation 94, 1298-1303 (1996).
-
(1996)
Circulation
, vol.94
, pp. 1298-1303
-
-
Taddei, S.1
-
27
-
-
10844240824
-
Impaired L-arginine transport and endothelial function in hypertensive and genetically predisposed normotensive subjects
-
Schlaich, M. P. et al. Impaired L-arginine transport and endothelial function in hypertensive and genetically predisposed normotensive subjects. Circulation 110, 3680-3686 (2004).
-
(2004)
Circulation
, vol.110
, pp. 3680-3686
-
-
Schlaich, M.P.1
-
28
-
-
77952953012
-
Impaired endothelial repair capacity of early endothelial progenitor cells in prehypertension: Relation to endothelial dysfunction
-
Giannotti, G. et al. Impaired endothelial repair capacity of early endothelial progenitor cells in prehypertension: relation to endothelial dysfunction. Hypertension 55, 1389-1397 (2010).
-
(2010)
Hypertension
, vol.55
, pp. 1389-1397
-
-
Giannotti, G.1
-
29
-
-
0027402809
-
Sustained hypertension induced by orally administered nitro-L-arginine
-
Dananberg, J., Sider, R. S. & Grekin, R. J. Sustained hypertension induced by orally administered nitro-L-arginine. Hypertension 21, 359-363 (1993).
-
(1993)
Hypertension
, vol.21
, pp. 359-363
-
-
Dananberg, J.1
Sider, R.S.2
Grekin, R.J.3
-
30
-
-
0029021148
-
Hypertension in mice lacking the gene for endothelial nitric oxide synthase
-
Huang, P. L. et al. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377, 239-242 (1995).
-
(1995)
Nature
, vol.377
, pp. 239-242
-
-
Huang, P.L.1
-
31
-
-
79958789023
-
AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive rats
-
Yang, Q. et al. AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive rats. Br. J. Pharmacol. 163, 1078-1085 (2011).
-
(2011)
Br. J. Pharmacol.
, vol.163
, pp. 1078-1085
-
-
Yang, Q.1
-
32
-
-
0037188941
-
Role of Akt signaling in vascular homeostasis and angiogenesis
-
Shiojima, I. & Walsh, K. Role of Akt signaling in vascular homeostasis and angiogenesis. Circ. Res. 90, 1243-1250 (2002).
-
(2002)
Circ. Res.
, vol.90
, pp. 1243-1250
-
-
Shiojima, I.1
Walsh, K.2
-
33
-
-
0036479305
-
Shear stress stimulates phosphorylation of endothelial nitricoxide synthase at Ser1179 by Akt-independent mechanisms: Role of protein kinase A
-
Boo, Y. C. et al. Shear stress stimulates phosphorylation of endothelial nitricoxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A. J. Biol. Chem. 277, 3388-3396 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3388-3396
-
-
Boo, Y.C.1
-
34
-
-
36349023095
-
Epinephrine regulation of the endothelial nitric-oxide synthase: Roles of RAC1 and beta3-adrenergic receptors in endothelial NO signaling
-
Kou, R. & Michel, T. Epinephrine regulation of the endothelial nitric-oxide synthase: roles of RAC1 and beta3-adrenergic receptors in endothelial NO signaling. J. Biol. Chem. 282, 32719-32729 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 32719-32729
-
-
Kou, R.1
Michel, T.2
-
35
-
-
61949165795
-
AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633
-
Chen, Z. et al. AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633. Circ. Res. 104, 496-505 (2009).
-
(2009)
Circ. Res.
, vol.104
, pp. 496-505
-
-
Chen, Z.1
-
36
-
-
77956294919
-
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation
-
Bungard, D. et al. Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. Science 329, 1201-1205 (2010).
-
(2010)
Science
, vol.329
, pp. 1201-1205
-
-
Bungard, D.1
-
37
-
-
77950989801
-
AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: Role of 26S proteasomes
-
Wang, S. et al. AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes. Circ. Res. 106, 1117-1128 (2010).
-
(2010)
Circ. Res.
, vol.106
, pp. 1117-1128
-
-
Wang, S.1
-
38
-
-
84874275609
-
AMPK alpha2 exerts its anti-inflammatory effects through PARP-1 and Bcl-6
-
Gongol, B. et al. AMPK alpha2 exerts its anti-inflammatory effects through PARP-1 and Bcl-6. Proc. Natl Acad. Sci. USA 110, 3161-3166 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 3161-3166
-
-
Gongol, B.1
-
39
-
-
33745946837
-
Bone morphogenic protein-4 induces hypertension in mice: Role of noggin, vascular NADPH oxidases, and impaired vasorelaxation
-
Miriyala, S. et al. Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation. Circulation 113, 2818-2825 (2006).
-
(2006)
Circulation
, vol.113
, pp. 2818-2825
-
-
Miriyala, S.1
-
40
-
-
52449102202
-
Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells
-
Csiszar, A., Labinskyy, N., Jo, H., Ballabh, P. & Ungvari, Z. Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 295, H569-H577 (2008).
-
(2008)
Am. J. Physiol. Heart Circ. Physiol.
, vol.295
, pp. H569-H577
-
-
Csiszar, A.1
Labinskyy, N.2
Jo, H.3
Ballabh, P.4
Ungvari, Z.5
-
41
-
-
77957373349
-
The contribution of the Tie2 lineage to primitive and definitive hematopoietic cells
-
Tang, Y., Harrington, A., Yang, X., Friesel, R. E. & Liaw, L. The contribution of the Tie2 lineage to primitive and definitive hematopoietic cells. Genesis 48, 563-567 (2010).
-
(2010)
Genesis
, vol.48
, pp. 563-567
-
-
Tang, Y.1
Harrington, A.2
Yang, X.3
Friesel, R.E.4
Liaw, L.5
-
42
-
-
52649097448
-
Immunological Genome Project Consortium. The Immunological Genome Project: Networks of gene expression in immune cells
-
Heng, T. S. & Painter, M. W.Immunological Genome Project Consortium. The Immunological Genome Project: networks of gene expression in immune cells. Nat. Immunol. 9, 1091-1094 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1091-1094
-
-
Heng, T.S.1
Painter, M.W.2
-
43
-
-
84878964648
-
Hypertension: Physiology and pathophysiology
-
Hall, J. E. et al. Hypertension: physiology and pathophysiology. Compr. Physiol. 2, 2393-2442 (2012).
-
(2012)
Compr. Physiol.
, vol.2
, pp. 2393-2442
-
-
Hall, J.E.1
-
44
-
-
6344292310
-
Endothelial nitric oxide synthase-deficient mice exhibit increased susceptibility to endotoxin-induced acute renal failure
-
Wang, W. et al. Endothelial nitric oxide synthase-deficient mice exhibit increased susceptibility to endotoxin-induced acute renal failure. Am. J. Physiol. Renal. Physiol. 287, F1044-F1048 (2004).
-
(2004)
Am. J. Physiol. Renal. Physiol.
, vol.287
, pp. F1044-F1048
-
-
Wang, W.1
-
45
-
-
84891845736
-
Hypertension and kidneys: Unraveling complex molecular mechanisms underlying hypertensive renal damage
-
Mennuni, S. et al. Hypertension and kidneys: unraveling complex molecular mechanisms underlying hypertensive renal damage. J. Hum. Hypertens. 28, 74-79 (2014).
-
(2014)
J. Hum. Hypertens.
, vol.28
, pp. 74-79
-
-
Mennuni, S.1
-
46
-
-
84901452658
-
Nephropathy and elevated BP in mice with podocytespecific NADPH oxidase 5 expression
-
Holterman, C. E. et al. Nephropathy and elevated BP in mice with podocytespecific NADPH oxidase 5 expression. J. Am. Soc. Nephrol. 25, 784-797 (2014).
-
(2014)
J. Am. Soc. Nephrol.
, vol.25
, pp. 784-797
-
-
Holterman, C.E.1
-
47
-
-
84906724883
-
The pathogenesis of focal segmental glomerulosclerosis
-
Jefferson, J. A. & Shankland, S. J. The pathogenesis of focal segmental glomerulosclerosis. Adv. Chronic Kidney Dis. 21, 408-416 (2014).
-
(2014)
Adv. Chronic Kidney Dis.
, vol.21
, pp. 408-416
-
-
Jefferson, J.A.1
Shankland, S.J.2
-
48
-
-
84897492148
-
Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis
-
Daehn, I. et al. Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis. J. Clin. Invest. 124, 1608-1621 (2014).
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 1608-1621
-
-
Daehn, I.1
-
49
-
-
79957605865
-
Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy
-
Tominaga, T. et al. Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy. J. Biol. Chem. 286, 20109-20116 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 20109-20116
-
-
Tominaga, T.1
-
51
-
-
0014352330
-
Metabolic studies on hypertensive patients with suppressed plasma renin activity not due to hyperaldosternosm
-
Helmer, O. M. & Judson, W. E. Metabolic studies on hypertensive patients with suppressed plasma renin activity not due to hyperaldosternosm. Circulation 38, 965-976 (1968).
-
(1968)
Circulation
, vol.38
, pp. 965-976
-
-
Helmer, O.M.1
Judson, W.E.2
-
52
-
-
84926422221
-
African Americans, hypertension and the renin angiotensin system
-
Williams, S. F., Nicholas, S. B., Vaziri, N. D. & Norris, K. C. African Americans, hypertension and the renin angiotensin system. World J. Cardiol. 6, 878-889 (2014).
-
(2014)
World J. Cardiol.
, vol.6
, pp. 878-889
-
-
Williams, S.F.1
Nicholas, S.B.2
Vaziri, N.D.3
Norris, K.C.4
-
53
-
-
0028973389
-
Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptide
-
Lopez, M. J. et al. Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptide. Nature 378, 65-68 (1995).
-
(1995)
Nature
, vol.378
, pp. 65-68
-
-
Lopez, M.J.1
-
54
-
-
0028943463
-
Genetic decreases in atrial natriuretic peptide and saltsensitive hypertension
-
John, S. W. et al. Genetic decreases in atrial natriuretic peptide and saltsensitive hypertension. Science 267, 679-681 (1995).
-
(1995)
Science
, vol.267
, pp. 679-681
-
-
John, S.W.1
-
55
-
-
67349208839
-
Genome-wide association study of blood pressure and hypertension
-
Levy, D. et al. Genome-wide association study of blood pressure and hypertension. Nat. Genet. 41, 677-687 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 677-687
-
-
Levy, D.1
-
56
-
-
79957585975
-
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians
-
Kato, N. et al. Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat. Genet. 43, 531-538 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 531-538
-
-
Kato, N.1
-
57
-
-
79151472509
-
Functional intronic polymorphisms: Buried treasure awaiting discovery within our genes
-
Cooper, D. N. Functional intronic polymorphisms: Buried treasure awaiting discovery within our genes. Hum. Genomics 4, 284-288 (2010).
-
(2010)
Hum. Genomics
, vol.4
, pp. 284-288
-
-
Cooper, D.N.1
-
58
-
-
49649086769
-
A functional intronic variant in the tyrosine hydroxylase (TH) gene confers risk of essential hypertension in the Northern Chinese Han population
-
Wang, L. et al. A functional intronic variant in the tyrosine hydroxylase (TH) gene confers risk of essential hypertension in the Northern Chinese Han population. Clin. Sci. 115, 151-158 (2008).
-
(2008)
Clin. Sci.
, vol.115
, pp. 151-158
-
-
Wang, L.1
-
59
-
-
80052964856
-
Understanding the contribution of synonymous mutations to human disease
-
Sauna, Z. E. & Kimchi-Sarfaty, C. Understanding the contribution of synonymous mutations to human disease. Nat. Rev. Genet. 12, 683-691 (2011).
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 683-691
-
-
Sauna, Z.E.1
Kimchi-Sarfaty, C.2
-
60
-
-
78649379906
-
Improved prediction of cardiovascular disease based on a panel of single nucleotide polymorphisms identified through genome-wide association studies
-
Davies, R. W. et al. Improved prediction of cardiovascular disease based on a panel of single nucleotide polymorphisms identified through genome-wide association studies. Circ. Cardiovasc.Genet. 3, 468-474 (2010).
-
(2010)
Circ. Cardiovasc.Genet.
, vol.3
, pp. 468-474
-
-
Davies, R.W.1
-
61
-
-
0036733653
-
A new method for large scale isolation of kidney glomeruli from mice
-
Takemoto, M. et al. A new method for large scale isolation of kidney glomeruli from mice. Am. J. Pathol. 161, 799-805 (2002).
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 799-805
-
-
Takemoto, M.1
-
62
-
-
23844557144
-
Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: A new therapeutic approach
-
Lautrette, A. et al. Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach. Nat. Med. 11, 867-874 (2005).
-
(2005)
Nat. Med.
, vol.11
, pp. 867-874
-
-
Lautrette, A.1
-
63
-
-
0037129827
-
Accurate normalization of real-time quantitative RTPCR data by geometric averaging of multiple internal control genes
-
Vandesompele, J. et al. Accurate normalization of real-time quantitative RTPCR data by geometric averaging of multiple internal control genes. Genome Biol. 3, RESEARCH0034 (2002).
-
(2002)
Genome Biol.
, vol.3
-
-
Vandesompele, J.1
-
64
-
-
84919427890
-
Predicting the effects of blood pressure-lowering treatment on major cardiovascular events for individual patients with type 2 diabetes mellitus: Results from Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation
-
van der Leeuw, J. et al. Predicting the effects of blood pressure-lowering treatment on major cardiovascular events for individual patients with type 2 diabetes mellitus: results from Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation. Hypertension 65, 115-121 (2015).
-
(2015)
Hypertension
, vol.65
, pp. 115-121
-
-
Van Der Leeuw, J.1
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