Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy

Journal of Biological Chemistry

Volumn 286, Issue 22, 2011, Pages 20109-20116

  Tominaga, Tatsuya ^a   Abe, Hideharu ^a   Ueda, Otoya ^b   Goto, Chisato ^b   Nakahara, Kunihiko ^c   Murakami, Taichi ^a   Matsubara, Takeshi ^e   Mima, Akira ^a   Nagai, Kojiro ^a   Araoka, Toshikazu ^a   Kishi, Seiji ^a   Fukushima, Naoshi ^d   Jishage, Kou Ichi ^b   Doi, Toshio ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b Chugai Research Institute for Medical Science Inc   (Japan)

^c HuBit Genomix Inc   (Japan)

^d CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^e KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SIGNALING; CHEMICAL ACTIVATION; DISEASES; EXPANSION; GLYCOSYLATION; MAMMALS;

ADVANCED GLYCATION END PRODUCTS; BONE MORPHOGENETIC PROTEIN-4; CHRONIC KIDNEY DISEASE; DIABETIC NEPHROPATHY; EXTRACELLULAR MATRIX PROTEIN; GLOMERULOSCLEROSIS; MOLECULAR MECHANISM; REGULATORY MECHANISM;

PROTEINS;

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; COLLAGEN TYPE 4; SMAD1 PROTEIN; TAMOXIFEN;

ALBUMINURIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; GLOMERULOSCLEROSIS; GLOMERULUS; MALE; MESANGIUM CELL; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE;

MUS; MUS MUSCULUS;

EID: 79957605865     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.179382     Document Type: Article

References (49)

1. Mason, R. M., and Wahab, N. A. (2003) J. Am. Soc. Nephrol. 14, 1358-1373
2. Kanwar, Y. S., Wada, J., Sun, L., Xie, P., Wallner, E. I., Chen, S., Chugh, S., and Danesh, F. R. (2008) Exp. Biol. Med. 233, 4-11
3. Doi, T., Vlassara, H., Kirstein, M., Yamada, Y., Striker, G. E., and Striker, L. J. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 2873-2877
4. Iehara, N., Takeoka, H., Yamada, Y., Kita, T., and Doi, T. (1996) Kidney Int. 50, 1166-1172
5. Bohlender, J. M., Franke, S., Stein, G., and Wolf, G. (2005) Am. J. Physiol. Renal. Physiol. 289, F645-F659
6. Abe, H., Matsubara, T., Iehara, N., Nagai, K., Takahashi, T., Arai, H., Kita, T., and Doi, T. (2004) J. Biol. Chem. 279, 14201-14206
7. Matsubara, T., Abe, H., Arai, H., Nagai, K., Mima, A., Kanamori, H., Sumi, E., Takahashi, T., Matsuura, M., Iehara, N., Fukatsu, A., Kita, T., and Doi, T. (2006) Lab. Invest. 86, 357-368
8. Mima, A., Arai, H., Matsubara, T., Abe, H., Nagai, K., Tamura, Y., Torikoshi, K., Araki, M., Kanamori, H., Takahashi, T., Tominaga, T., Matsuura, M., Iehara, N., Fukatsu, A., Kita, T., and Doi, T. (2008) Diabetes 57, 1712-1722
9. Miyazono, K., Maeda, S., and Imamura, T. (2005) Cytokine Growth Factor Rev. 16, 251-263
10. Heldin, C. H., Miyazono, K., and ten Dijke, P. (1997) Nature 390, 465-471
11. Fogo, A. B. (2000) Am. J. Kidney Dis. 35, 179-188
12. Fukami, K., Ueda, S., Yamagishi, S., Kato, S., Inagaki, Y., Takeuchi, M., Motomiya, Y., Bucala, R., Iida, S., Tamaki, K., Imaizumi, T., Cooper, M. E., and Okuda, S. (2004) Kidney Int. 66, 2137-2147
13. Lewis, E. J., Hunsicker, L. G., Bain, R. P., and Rohde, R. D. (1993) N. Engl. J. Med. 329, 1456-1462
14. Lewis, E. J., Hunsicker, L. G., Clarke, W. R., Berl, T., Pohl, M. A., Lewis, J. B., Ritz, E., Atkins, R. C., Rohde, R., and Raz, I. (2001) N. Engl. J. Med. 345, 851-860
15. Niwa, H., Yamamura, K., and Miyazaki, J. (1991) Gene 108, 193-199
16. Zhang, Y., Riesterer, C., Ayrall, A. M., Sablitzky, F., Littlewood, T. D., and Reth, M. (1996) Nucleic Acids Res. 24, 543-548
17. Scherrer, L. C., Picard, D., Massa, E., Harmon, J. M., Simons, S. S., Jr., Yamamoto, K. R., and Pratt, W. B. (1993) Biochemistry 32, 5381-5386
18. Verrou, C., Zhang, Y., Zürn, C., Schamel, W. W., and Reth, M. (1999) Biol. Chem. 380, 1435-1438
19. Winnier, G., Blessing, M., Labosky, P. A., and Hogan, B. L. (1995) Genes Dev. 9, 2105-2116
20. Davies, M. (1994) Kidney Int. 45, 320-327
21. Yamagishi, S., Inagaki, Y., Okamoto, T., Amano, S., Koga, K., Takeuchi, M., and Makita, Z. (2002) J. Biol. Chem. 277, 20309-20315
22. Takahashi, T., Abe, H., Arai, H., Matsubara, T., Nagai, K., Matsuura, M., Iehara, N., Yokode, M., Nishikawa, S., Kita, T., and Doi, T. (2005) J. Biol. Chem. 280, 7100-7106
23. Lander, H. M., Tauras, J. M., Ogiste, J. S., Hori, O., Moss, R. A., and Schmidt, A. M. (1997) J. Biol. Chem. 272, 17810-17814
24. Hofmann, M. A., Drury, S., Fu, C., Qu, W., Taguchi, A., Lu, Y., Avila, C., Kambham, N., Bierhaus, A., Nawroth, P., Neurath, M. F., Slattery, T., Beach, D., McClary, J., Nagashima, M., Morser, J., Stern, D., and Schmidt, A. M. (1999) Cell 97, 889-901
25. Yamamoto, Y., Kato, I., Doi, T., Yonekura, H., Ohashi, S., Takeuchi, M., Watanabe, T., Yamagishi, S., Sakurai, S., Takasawa, S., Okamoto, H., and Yamamoto, H. (2001) J. Clin. Invest. 108, 261-268
26. Miyazaki, Y., Ueda, H., Yokoo, T., Utsunomiya, Y., Kawamura, T., Matsusaka, T., Ichikawa, I., and Hosoya, T. (2006) Biochem. Biophys. Res. Commun. 340, 681-688
27. Akagi, Y., Isaka, Y., Akagi, A., Ikawa, M., Takenaka, M., Moriyama, T., Yamauchi, A., Horio, M., Ueda, N., Okabe, M., and Imai, E. (1997) Kidney Int. 51, 1265-1269
28. Beisswenger, P. G., and Spiro, R. G. (1970) Science 168, 596-598
29. Kanwar, Y. S., Rosenzweig, L. J., Linker, A., and Jakubowski, M. L. (1983) Proc. Natl. Acad. Sci. U.S.A. 80, 2272-2275
30. Pirart, J. (1977) Diabete Metab. 3, 245-256
31. (1993) N. Engl. J. Med. 329, 977-986
32. Hasslacher, C., Reichenbacher, R., Gechter, F., and Timpl, R. (1984) Diabetologia 26, 150-154
33. Ohashi, S., Abe, H., Takahashi, T., Yamamoto, Y., Takeuchi, M., Arai, H., Nagata, K., Kita, T., Okamoto, H., Yamamoto, H., and Doi, T. (2004) J. Biol. Chem. 279, 19816-19823
34. Yamamoto, Y., Doi, T., Kato, I., Shinohara, H., Sakurai, S., Yonekura, H., Watanabe, T., Myint, K. M., Harashima, A., Takeuchi, M., Takasawa, S., Okamoto, H., Hashimoto, N., Asano, M., and Yamamoto, H. (2005) Ann. N.Y. Acad. Sci. 1043, 562-566
35. Myint, K. M., Yamamoto, Y., Doi, T., Kato, I., Harashima, A., Yonekura, H., Watanabe, T., Shinohara, H., Takeuchi, M., Tsuneyama, K., Hashimoto, N., Asano, M., Takasawa, S., Okamoto, H., and Yamamoto, H. (2006) Diabetes 55, 2510-2522
36. Yang, C. W., Vlassara, H., Peten, E. P., He, C. J., Striker, G. E., and Striker, L. J. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 9436-9440
37. Sanderson, N., Factor, V., Nagy, P., Kopp, J., Kondaiah, P., Wakefield, L., Roberts, A. B., Sporn, M. B., and Thorgeirsson, S. S. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 2572-2576
38. Zhou, G., Li, C., and Cai, L. (2004) Am. J. Pathol. 165, 2033-2043
39. Sato, M., Muragaki, Y., Saika, S., Roberts, A. B., and Ooshima, A. (2003) J. Clin. Invest. 112, 1486-1494
40. Fujimoto, M., Maezawa, Y., Yokote, K., Joh, K., Kobayashi, K., Kawamura, H., Nishimura, M., Roberts, A. B., Saito, Y., and Mori, S. (2003) Biochem. Biophys. Res. Commun. 305, 1002-1007
41. Ziyadeh, F. N., Hoffman, B. B., Han, D. C., Iglesias-De La Cruz, M. C., Hong, S. W., Isono, M., Chen, S., McGowan, T. A., and Sharma, K. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 8015-8020
42. Huang, S., Flanders, K. C., and Roberts, A. B. (2000) Gene 258, 43-53
43. Massagué, J., Attisano, L., and Wrana, J. L. (1994) Trends Cell Biol. 4, 172-178
44. ten Dijke, P., Yamashita, H., Ichijo, H., Franzén, P., Laiho, M., Miyazono, K., and Heldin, C. H. (1994) Science 264, 101-104
45. Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., and Massagué, J. (1994) Nature 370, 341-347
46. Wozney, J. M., Rosen, V., Celeste, A. J., Mitsock, L. M., Whitters, M. J., Kriz, R. W., Hewick, R. M., and Wang, E. A. (1988) Science 242, 1528-1534
47. McCauley, D. W., and Bronner-Fraser, M. (2004) Evol. Dev. 6, 411-422
48. Wang, X., Harris, R. E., Bayston, L. J., and Ashe, H. L. (2008) Nature 455, 72-77
49. Yang, Y. L., Liu, Y. S., Chuang, L. Y., Guh, J. Y., Lee, T. C., Liao, T. N., Hung, M. Y., and Chiang, T. A. (2009) Endocrinology 150, 727-740