Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer

Journal of Clinical Investigation

Volumn 125, Issue 12, 2015, Pages 4625-4637

  Rondinelli, Beatrice ^a,b,h   Rosano, Dalia ^a   Antonini, Elena ^a   Frenquelli, Michela ^a   Montanini, Laura ^b   Huang, Dachuan ^c   Segalla, Simona ^a   Yoshihara, Kosuke ^d   Amin, Samir B ^e   Lazarevic, Dejan ^a   Tean, Bin ^c   Verhaak, Roel G W ^d,e   Andrew Futreal, P ^e   Di Croce, Luciano ^f,g   Chin, Lynda ^e   Cittaro, Davide ^a   Tonon, Giovanni ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^d Department of Bioinformatics and Computational Biology ^*  (Singapore)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^f UNIVERSITAT POMPEU FABRA   (Spain)

^g INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^h DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN DDB1; CULLIN; CULLIN 4; HISTONE DEMETHYLASE; HISTONE DEMETHYLASE JARID1C; HISTONE H3; LYSINE; TUMOR MARKER; UNCLASSIFIED DRUG; UNTRANSLATED RNA; DDB1 PROTEIN, HUMAN; DDB1 PROTEIN, MOUSE; DNA BINDING PROTEIN; HETEROCHROMATIN; HISTONE; KDM5C PROTEIN, HUMAN; KDM5C PROTEIN, MOUSE; METHYLTRANSFERASE; N DEMETHYLASE; REPRESSOR PROTEIN; SUV39H1 PROTEIN, HUMAN; SUV39H1 PROTEIN, MOUSE; TUMOR PROTEIN;

ANIMAL CELL; ARTICLE; CANCER PATIENT; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME REPLICATION; CONTROLLED STUDY; EMBRYO; ENZYME INACTIVATION; FEMALE; GENE EXPRESSION; GENE MUTATION; GENE REARRANGEMENT; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENOME; GENOMIC INSTABILITY; HETEROCHROMATIN; HISTONE DEMETHYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; 3T3 CELL LINE; ANIMAL; ENZYMOLOGY; GENETICS; HELA CELL LINE; KIDNEY TUMOR; METABOLISM; METHYLATION; MUTATION; PATHOLOGY;

ANIMALS; CARCINOMA, RENAL CELL; DNA-BINDING PROTEINS; GENOMIC INSTABILITY; HELA CELLS; HETEROCHROMATIN; HISTONE DEMETHYLASES; HISTONES; HUMANS; KIDNEY NEOPLASMS; METHYLATION; METHYLTRANSFERASES; MICE; MUTATION; NEOPLASM PROTEINS; NIH 3T3 CELLS; OXIDOREDUCTASES, N-DEMETHYLATING; REPRESSOR PROTEINS;

EID: 84948783353     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI81040     Document Type: Article

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