Proliferating cell nuclear antigen is required for loading of the SMCX/KMD5C histone demethylase onto chromatin

Epigenetics and Chromatin

Volumn 4, Issue 1, 2011, Pages

  Liang, Zhihui ^a,d   Diamond, Marc ^a,e   Smith, Johanna A ^a   Schnell, Matthias ^a   Daniel, René ^a,b,c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYCLINE; HISTONE DEMETHYLASE; HISTONE H3; LYSINE; LYSINE SPECIFIC DEMETHYLASE 5C; OXYGENASE; REGULATORY ELEMENT 1 SILENCING TRANSCRIPTION FACTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CELL MIGRATION; CHROMATIN; DEMETHYLATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS;

EID: 80053908882     PISSN: None     EISSN: 17568935     Source Type: Journal    
DOI: 10.1186/1756-8935-4-18     Document Type: Article

References (31)

1. Molecular Signals of epigenetic states. Bonasio R, Tu S, Reinberg D, Science 2010 330 612 616 10.1126/science.1191078 21030644
2. The logic of chromatin architecture and remodelling on promoters. Cairns BR, Nature 2009 461 193 198 10.1038/nature08450 19741699
3. Chromatin modifications and their function. Kouzarides T, Cell 2007 128 693 705 10.1016/j.cell.2007.02.005 17320507 (Pubitemid 46273577)
4. Histone variants-ancient wrap artisits of the epigenome. Talbert PB, Henikoff S, Nat Rev Mol Cell Biol 11 264 275
5. Epigenetic modifications in double-strand break DNA damage signalling and repair. Rossetto D, Truman AW, Kron SJ, Cote J, Clin Cancer Res 2010 16 4543 4552 10.1158/1078-0432.CCR-10-0513 20823147
6. Methylation: lost in hydroxylation? Trewick SC, McLaughlin PJ, Allshire RC, EMBO Rep 2005 6 315 320 10.1038/sj.embor.7400379 15809658 (Pubitemid 40561622)
7. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA, Cell 2004 119 941 953 10.1016/j.cell.2004.12.012 15620353 (Pubitemid 40037608)
8. The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Iwase S, Lan F, Bayliss P, de la Torre-Ubieta L, Huarte M, Qi HH, Whetstine JR, Bonni A, Roberts TM, Shi Y, Cell 2007 128 1077 1088 10.1016/j.cell.2007.02.017 17320160 (Pubitemid 46437259)
9. A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human. Agulnik AI, Mitchell MJ, Mattei MG, Borsani G, Avner PA, Lerner JL, Bishop CE, Hum Mol Genet 1994 3 879 884 10.1093/hmg/3.6.879 7951230 (Pubitemid 24189952)
10. Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation. Jensen LR, Amende M, Gurok U, Moser B, Gimmel V, Tzschach A, Janecke AR, Tariverdian G, Chelly J, Fryns JP, Van Esch H, Kleefstra T, Hamel B, Moraine C, Gecz J, Turner G, Reinhardt R, Kalscheuer VM, Ropers HH, Lenzner S, Am J Hum Genet 2005 76 227 236 10.1086/427563 15586325 (Pubitemid 40129549)
11. A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C. Jensen LR, Bartenschlager H, Rujirabanjerd S, Tzschach A, Numann A, Janecke AR, Sporle R, Stricker S, Raynaud M, Nelson J, Hackett A, Fryns JP, Chelly J, de Brouwer AP, Hamel B, Gecz J, Ropers HH, Kuss AW, Pathogenetics 2010 3 2 10.1186/1755-8417-3-2 20181063
12. Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype-phenotype correlation. Rujirabanjerd S, Nelson J, Tarpey PS, Hackett A, Edkins S, Raymond FL, Schwartz CE, Turner G, Iwase S, Shi Y, Futreal PA, Stratton MR, Gecz J, Eur J Hum Genet 2010 18 330 335 10.1038/ejhg.2009.175 19826449
13. A novel mutation in JARID1C gene associated with mental retardation. Santos C, Rodriguez-Revenga L, Madrigal I, Badenas C, Pineda M, Mila M, Eur J Hum Genet 2006 14 583 586 10.1038/sj.ejhg.5201608 16538222
14. Novel JARID1C/SMCX mutations in patients with X-linked mental retardation. Tzschach A, Lenzner S, Moser B, Reinhardt R, Chelly J, Fryns JP, Kleefstra T, Raynaud M, Turner G, Ropers HH, Kuss A, Jensen LR, Hum Mutat 2006 27 389 16541399
15. A novel mutation in JARID1C/SMCX in a patient with autism spectrum disorder (ASD). Adegbola A, Gao H, Sommer S, Browning M, Am J Med Genet A 2008 146A 505 511 10.1002/ajmg.a.32142 18203167 (Pubitemid 351206826)
16. RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3. Christensen J, Agger K, Cloos PA, Pasini D, Rose S, Sennels L, Rappsilber J, Hansen KH, Salcini AE, Helin K, Cell 2007 128 1063 1076 10.1016/j.cell.2007.02.003 17320161 (Pubitemid 46427869)
17. Repression of Smad3 activity by histone demethylase SMCX/JARID1C. Kim TD, Shin S, Janknecht R, Biochem Biophys Res Commun 2008 366 563 567 10.1016/j.bbrc.2007.12.013 18078810 (Pubitemid 50012656)
18. The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Tahiliani M, Mei P, Fang R, Leonor T, Rutenberg M, Shimizu F, Li J, Rao A, Shi Y, Nature 2007 447 601 605 10.1038/nature05823 17468742 (Pubitemid 46868038)
19. A role for the Werner syndrome protein in epigenetic inactivation of the pluripotency factor Oct4. Smith JA, Ndoye AM, Geary K, Lisanti MP, Igoucheva O, Daniel R, Aging Cell 2010 9 580 591 10.1111/j.1474-9726.2010.00585.x 20477760
20. Proliferating cell nuclear antigen (PCNA): a dancer with many partners. Maga G, Hubscher U, J Cell Sci 2003 116 3051 3060 10.1242/jcs.00653 12829735 (Pubitemid 37038954)
21. Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Gulbis JM, Kelman Z, Hurwitz J, O'Donnell M, Kuriyan J, Cell 1996 87 297 306 10.1016/S0092-8674(00)81347-1 8861913 (Pubitemid 26359007)
22. Structural basis for recruitment of human flap endonuclease 1 to PCNA. Sakurai S, Kitano K, Yamaguchi H, Hamada K, Okada K, Fukuda K, Uchida M, Ohtsuka E, Morioka H, Hakoshima T, EMBO J 2005 24 683 693 10.1038/sj.emboj.7600519 15616578 (Pubitemid 40396099)
23. The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase. Vijayakumar S, Chapados BR, Schmidt KH, Kolodner RD, Tainer JA, Tomkinson AE, Nucleic Acids Res 2007 35 1624 1637 10.1093/nar/gkm006 17308348 (Pubitemid 46592882)
24. Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes. Dalgliesh GL, Furge K, Greenman C, Chen L, Bignell G, Butler A, Davies H, Edkins S, Hardy C, Latimer C, Teague J, Andrews J, Barthorpe S, Beare D, Buck G, Campbell PJ, Forbes S, Jia M, Jones D, Knott H, Kok CY, Lau KW, Leroy C, Lin ML, McBride DJ, Maddison M, Maguire S, McLay K, Menzies A, Mironenko T, Mulderrig L, Mudie L, O'Meara S, Pleasance E, Rajasingham A, Shepherd R, Smith R, Stebbings L, Stephens P, Tang G, Tarpey PS, Turrell K, Dykema KJ, Khoo SK, Petillo D, Wondergem B, Anema J, Kahnoski RJ, Teh BT, Stratton MR, Futreal PA, Nature 2010 463 360 363 10.1038/nature08672 20054297
25. Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression. Smith JA, White EA, Sowa ME, Powell ML, Ottinger M, Harper JW, Howley PM, Proc Natl Acad Sci USA 2010 107 3752 3757 10.1073/pnas.0914818107 20133580
26. RE-1-silencing transcription factor shows tumor-suppressor functions and negatively regulates the oncogenic TAC1 in breast cancer cells. Reddy BY, Greco SJ, Patel PS, Trzaska KA, Rameshwar P, Proc Natl Acad Sci USA 2009 106 4408 4413 10.1073/pnas.0809130106 19246391
27. Methylated H3K4, a transcription-associated histone modification, is involved in the DNA damage response pathway. Faucher D, Wellinger RJ, PLoS Genet 2010 6, pii 1001082
28. Reading, writing and editing methylated lysines on histone tails: new insights from recent structural studies. Justin N, De Marco V, Aasland R, Gamblin SJ, Curr Opin Struct Biol 2010 20 730 738 10.1016/j.sbi.2010.09.012 20956082
29. Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase. Liang G, Klose RJ, Gardner KE, Zhang Y, Nat Struct Mol Biol 2007 14 243 245 10.1038/nsmb1204 17310254 (Pubitemid 46355574)
30. Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression. Mersman DP, Du HN, Fingerman IM, South PF, Briggs SD, Genes Dev 2009 23 951 962 10.1101/gad.1769209 19346402
31. PCNA, the maestro of the replication fork. Moldovan GL, Pfander B, Jentsch S, Cell 2007 129 665 679 10.1016/j.cell.2007.05.003 17512402 (Pubitemid 46802385)