Activation of peroxisome proliferator-activated receptor-β/-δ (PPARβ/δ) prevents endothelial dysfunction in type 1 diabetic rats

Free Radical Biology and Medicine

Volumn 53, Issue 4, 2012, Pages 730-741

  Quintela, Ana María ^a   Jiménez, Rosario ^a   Gómez Guzmán, Manuel ^a   Zarzuelo, María José ^a   Galindo, Pilar ^a   Sánchez, Manuel ^a   Vargas, Félix ^a   Cogolludo, Ángel ^b,c   Tamargo, Juan ^b   Pérez Vizcaíno, Francisco ^b,c   Duarte, Juan ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Diabetic rat; Endothelial dysfunction; NADPH oxidase; PPAR

Indexed keywords

[4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; ACETYLCHOLINE; BETA ACTIN; CARNITINE PALMITOYLTRANSFERASE I; CAVEOLIN 1; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GSK 0660; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ANTAGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PREPROENDOTHELIN 1; PROTEIN P22; PROTEIN P47; PYRUVATE DEHYDROGENASE KINASE 4; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; SUPEROXIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HEART RATE; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; VASCULAR RING; VASODILATATION;

ACETYLCHOLINE; ANIMALS; AORTA; BLOOD PRESSURE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC ANGIOPATHIES; ENDOTHELIAL CELLS; ENDOTHELIN-1; GENE EXPRESSION; GENE EXPRESSION REGULATION; MACROPHAGES; NADPH OXIDASE; NEUTROPHIL INFILTRATION; PEROXIDASE; PPAR DELTA; PPAR-BETA; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; STREPTOZOCIN; THIAZOLES; TRIGLYCERIDES; VASODILATION; VASODILATOR AGENTS;

RATTUS;

EID: 84864331653     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.05.045     Document Type: Article

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