Sodium tanshinone IIA silate inhibits high glucose- Induced vascular smooth muscle cell proliferation and migration through activation of amp-activated protein kinase

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Wu, Wen Yu ^a,b   Yan, Hong ^b   Wang, Xin Bo ^b   Gui, Yu Zhou ^b   Gao, Fei ^b   Tang, Xi Lan ^a   Qin, Yin Lin ^c   Su, Mei ^c   Chen, Tao ^c   Wang, Yi Ping ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c Nanjing Carefree Medical Technology Co Ltd   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; GELATINASE A; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; SODIUM TANSHINONE IIA; TANSHINONE IIA; UNCLASSIFIED DRUG; ABIETANE DERIVATIVE; HERBACEOUS AGENT; TANSHINONE; THREONINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL MIGRATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TREATMENT DURATION; VASCULAR SMOOTH MUSCLE; VASCULAR SMOOTH MUSCLE CELL; WESTERN BLOTTING; ANIMAL; CELL CYCLE CHECKPOINT; CELL MOTION; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; FLOW CYTOMETRY; GENETICS; METABOLISM; MOUSE MUTANT; MUTANT MOUSE STRAIN; PHOSPHORYLATION; PRIMARY CELL CULTURE; RNA INTERFERENCE; SPRAGUE DAWLEY RAT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AORTA; BLOTTING, WESTERN; CELL CYCLE CHECKPOINTS; CELL MOVEMENT; CELL PROLIFERATION; DIABETES MELLITUS, TYPE 2; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; ENZYME ACTIVATION; FLOW CYTOMETRY; GLUCOSE; MALE; MICE; MICE, MUTANT STRAINS; MICE, OBESE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PRIMARY CELL CULTURE; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; THREONINE;

EID: 84899766217     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094957     Document Type: Article

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