Interferon regulatory factor-1 together with reactive oxygen species promotes the acceleration of cell cycle progression by up-regulating the cyclin E and CDK2 genes during high glucose-induced proliferation of vascular smooth muscle cells

Cardiovascular Diabetology

Volumn 12, Issue 1, 2013, Pages

  Zhang, Xi ^a   Liu, Long ^b   Chen, Chao ^c   Chi, Ya Li ^a   Yang, Xiang Qun ^a   Xu, Yan ^d   Li, Xiao Tong ^a   Guo, Shi Lei ^d   Xiong, Shao Hu ^a   Shen, Man Ru ^e   Sun, Yu ^a   Zhang, Chuan Sen ^a   Hu, Kai Meng ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

^d Nanjing RegeneCure Biotech Co Ltd   (China)

^e FUDAN UNIVERSITY   (China)

Author keywords

Cell cycle; Cell proliferation; Interferon regulatory factor 1; Reactive oxygen species; Vascular smooth muscle cells

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CYCLIN DEPENDENT KINASE 2; CYCLIN E; GLUCOSE; HYDROGEN PEROXIDE; INTERFERON REGULATORY FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; NONHUMAN; RAT; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANTIOXIDANTS; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D1; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; DIABETIC ANGIOPATHIES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUCOSE; INTERFERON REGULATORY FACTOR-1; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFECTION; UP-REGULATION;

EID: 84885358157     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-12-147     Document Type: Article

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