Vaspin attenuates high glucose-induced vascular smooth muscle cells proliferation and chemokinesis by inhibiting the MAPK, PI3K/Akt, and NF-κB signaling pathways

Atherosclerosis

Volumn 228, Issue 1, 2013, Pages 61-68

  Li, Hailing ^a   Peng, Wenhui ^a   Zhuang, Jianhui ^a   Lu, Yuyan ^a   Jian, Weixia ^b   Wei, Yidong ^a   Li, Weiming ^a   Xu, Yawei ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Adipokine; Proliferation; Reactive oxygen species; Signal transduction; Vascular smooth muscle cell

Indexed keywords

CYCLIN D1; CYCLINE; GLUCOSE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; PROTEIN P47; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STRESS ACTIVATED PROTEIN KINASE 1; VASPIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL PROLIFERATION; CELL STIMULATION; CHEMOKINESIS; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HYPERGLYCEMIA; IMMUNOBLOTTING; INTRACELLULAR SIGNALING; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SMOOTH MUSCLE FIBER; TRANSCRIPTION REGULATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, THORACIC; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; CHEMOKINES; GLUCOSE; MALE; MAP KINASE SIGNALING SYSTEM; MUSCLE, SMOOTH, VASCULAR; NADPH OXIDASE; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SERPINS;

EID: 84876805071     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2013.02.013     Document Type: Article

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