Disruption in the balance between goal-directed behavior and habit learning in obsessive-compulsive disorder

American Journal of Psychiatry

Volumn 168, Issue 7, 2011, Pages 718-726

  Gillan, Claire M ^a,b,c,d,e   Papmeyer, Martina ^a,b,c,d,e   Morein Zamir, Sharon ^a,b,c,d,e   Sahakian, Barbara J ^a,b,c,d,e   Fineberg, Naomi A ^a,b,c,d,e   Robbins, Trevor W ^a,b,c,d,e   De Wit, Sanne ^a,b,c,d,e  

^a UK   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c QUEEN ELIZABETH II HOSPITAL   (United Kingdom)

^d UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^e UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PSYCHOTROPIC AGENT; RISPERIDONE; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; COMORBIDITY; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISCRIMINATION LEARNING; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HABIT; HABITUAL ADAPTATION; HUMAN; LEARNING; MALE; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; STATE TRAIT ANXIETY INVENTORY; STIMULUS RESPONSE;

ADULT; BEHAVIOR CONTROL; COMPULSIVE BEHAVIOR; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISCRIMINATION LEARNING; FEMALE; FUNCTIONAL LATERALITY; GOALS; HABITS; HUMANS; INTENTION; MALE; MIDDLE AGED; OBSESSIVE-COMPULSIVE DISORDER; PERSONALITY INVENTORY; PSYCHIATRIC STATUS RATING SCALES; PSYCHOMOTOR PERFORMANCE; QUESTIONNAIRES;

EID: 79960520781     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2011.10071062     Document Type: Article

References (47)

1. Fineberg NA, Potenza MN, Chamberlain SR, Berlin HA, Menzies L, Bechara A, Sahakian BJ, Robbins TW, Bullmore ET, Hollander E: Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review. Neuropsychopharmacology 2010; 35:591-604
2. Graybiel AM, Rauch SL: Toward a neurobiology of obsessivecompulsive disorder. Neuron 2000; 28:343-347
3. Boulougouris V, Chamberlain SR, Robbins TW: Cross-species models of OCD spectrum disorders. Psychiatry Res 2009; 170:15-21
4. Dickinson A, Balleine B: Actions and responses: the dual psychology of behavior, in Spatial Representation: Problems in Philosophy and Psychology. Edited by Eilan N, McCarthy RA, Brewer B. Malden, Mass, Blackwell Scientific Publishing, 1993, pp 277-293
5. de Wit S, Dickinson A: Associative theories of goal-directed behaviour: a case for animal-human translational models. Psychol Res 2009; 73:463-476
6. Adams C, Dickinson A: Instrumental responding following reinforcer devaluation. Q J Exp Psychol 1981; 33:109-121
7. Adams C: Variations in the sensitivity of instrumental responding to reinforcer devaluation. Q J Exp Psychol 1982; 34B:77-98
8. Thorndike A: Animal Intelligence: Experimental Studies. New York, M acmillan, 1911
9. Yin HH, Ostlund SB, Knowlton BJ, Balleine BW: The role of the dorsomedial striatum in instrumental conditioning. Eur J Neurosci 2005; 22:513-523 (Pubitemid 41097624)
10. Killcross S, Coutureau E: Coordination of actions and habits in the medial prefrontal cortex of rats. Cereb Cortex 2003; 13:400-408 (Pubitemid 36373685)
11. Corbit LH, Balleine BW: The role of prelimbic cortex in instrumental conditioning. Behav Brain Res 2003; 146:145-157 (Pubitemid 37476141)
12. Valentin VV, Dickinson A, O'Doherty JP: Determining the neural substrates of goal-directed learning in the human brain. Neurosci 2007; 27:4019-4026 (Pubitemid 46597159)
13. de Wit S, Corlett PR, Aitken MR, Dickinson A, Fletcher PC: Differential engagement of the ventromedial prefrontal cortex by goal-directed and habitual behavior toward food pictures in humans. J Neurosci 2009; 29:11330-11338
14. Everitt BJ, Robbins TW: Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci 2005; 8:1481-1489 (Pubitemid 41573659)
15. Menzies L, Williams GB, Chamberlain SR, Ooi C, Fineberg N, Suckling J, Sahakian BJ, Robbins TW, Bullmore ET: White matter abnormalities in patients with obsessive-compulsive disorder and their first-degree relatives. Am J Psychiatry 2008; 165:1308-1315
16. Saxena S, Rauch SL: Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder. Psychiatr Clin North Am 2000; 23:563-586 (Pubitemid 30666507)
17. Tricomi EM, Delgado MR, Fiez JA: Modulation of caudate activity by action contingency. Neuron 2004; 41:281-292 (Pubitemid 38125188)
18. Tanaka SC, Balleine BW, O'Doherty JP: Calculating consequences: brain systems that encode the causal effects of actions. Neurosci 2008; 28:6750-6755
19. Yin HH, Knowlton BJ, Balleine BW: Lesions of dorsolateral striatum preserve outcome expectancy but disrupt habit formation in instrumental learning. Eur J Neurosci 2004; 19:181-189 (Pubitemid 38122084)
20. Tricomi E, Balleine BW, O'Doherty JP: A specific role for posterior dorsolateral striatum in human habit learning. Eur J Neurosci 2009; 29:2225-2232
21. Coutureau E, Killcross S: Inactivation of the infralimbic prefrontal cortex reinstates goal-directed responding in overtrained rats. Behav Brain Res 2003; 146:167-174 (Pubitemid 37476143)
22. Alexander GE, DeLong MR, Strick PL: Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 1986; 9:357-381 (Pubitemid 16055790)
23. de Wit S, Barker RA, Dickinson T, Cools R: Habitual versus goal-directed action control in Parkinson's disease. J Cogn Neurosci 2011; 23:1218-1229
24. de Wit S, Niry D, Wariyar R, Aitken MR, Dickinson A: Stimulus-outcome interactions during instrumental discrimination learning by rats and humans. J Exp Psychol Anim Behav Process 2007; 33:1-11 (Pubitemid 46130121)
25. Crockett MJ, Clark L, Robbins TW: Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. J Neurosci 2009; 29:11993-11999
26. Camille N, Coricelli G, Sallet J, Pradat-Diehl P, Duhamel JR, Sirigu A: The involvement of the orbitofrontal cortex in the experience of regret. Science 2004; 304:1167-1170 (Pubitemid 38661855)
27. Nelson HE: National Adult Reading Test (NART): Test Manual. Windsor, UK, NFER-Nelson, 1982
28. Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS: The Yale-Brown Obsessive Compulsive Scale (Y-BOCS), part 1: development, use, and reliability. Arch Gen Psychiatry 1989; 46:1006-1011 (Pubitemid 19278229)
29. Foa EB, Huppert JD, Leiberg S, Langner R, Kichic R, Hajcak G, Salkovskis PM: The Obsessive-Compulsive Inventory: development and validation of a short version. Psychol Assess 2002; 14:485-496 (Pubitemid 35440493)
30. Mataix-Cols D, Rosario-Campos MC, Leckman JF: A multidimensional model of obsessive-compulsive disorder. Am J Psychiatry 2005; 162:228-238
31. Montgomery SA, Åsberg M: A new depression scale designed to be sensitive to change. Br J Psychiatry 1979; 134:382-389 (Pubitemid 9136500)
32. Spielberger CD: State-Trait Anxiety Inventory (STAI). Palo Alto, Calif, Consulting Psychologists Press, 1985
33. Schwabe L, Wolf OT: Stress prompts habit behavior in humans. J Neurosci 2009; 29:7191-7198
34. Schwabe L, Wolf OT: Socially evaluated cold pressor stress after instrumental learning favors habits over goal-directed action. Psychoneuroendocrinology 2010; 35:977-986
35. Eysenck MW, Derakshan N, Santos R, Calvo MG: Anxiety and cognitive performance: attentional control theory. Emotion 2007; 7:336-353 (Pubitemid 46800375)
36. Glascher J, Hampton AN, O'Doherty JP: Determining a role for ventromedial prefrontal cortex in encoding action-based value signals during reward-related decision making. Cereb Cortex 2009; 19:483-495
37. Menzies L, Chamberlain SR, Laird AR, Thelen SM, Sahakian BJ, Bullmore ET: Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: the orbitofronto-striatal model revisited. Neurosci Biobehav Rev 2008; 32:525-549 (Pubitemid 351173336)
38. Rauch SL, Jenike MA, Alpert NM, Baer L, Breiter HC, Savage CR, Fischman AJ: Regional cerebral blood flow measured during symptom provocation in obsessive-compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography. Arch Gen Psychiatry 1994; 51:62-70 (Pubitemid 24028999)
39. Saxena S, Brody AL, Schwartz JM, Baxter LR: Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder. Br J Psychiatry Suppl 1998; 35:26-37 (Pubitemid 28368348)
40. Chamberlain SR, Fineberg NA, Menzies LA, Blackwell AD, Bullmore ET, Robbins TW, Sahakian BJ: Impaired cognitive flexibility and motor inhibition in unaffected first-degree relatives of patients with obsessive-compulsive disorder. Am J Psychiatry 2007; 164:335-338
41. Balleine BW, O'Doherty JP: Human and rodent homologies in action control: corticostriatal determinants of goal-directed and habitual action. Neuropsychopharmacology 2010; 35:48-69
42. Joel D, Zohar O, Afek M, Hermesh H, Lerner L, Kuperman R, Gross-Isseroff R, Weizman A, Inzelberg R: Impaired procedural learning in obsessive-compulsive disorder and Parkinson's disease, but not in major depressive disorder. Behav Brain Res 2005; 157:253-263 (Pubitemid 40082568)
43. Rauch SL, Wedig MM, Wright CI, Martis B, McMullin KG, Shin LM, Cannistraro PA, Wilhelm S: Functional magnetic resonance imaging study of regional brain activation during implicit sequence learning in obsessive-compulsive disorder. Biol Psychiatry 2007; 61:330-336 (Pubitemid 46108676)
44. Kathmann N, Rupertseder C, Hauke W, Zaudig M: Implicit sequence learning in obsessive-compulsive disorder: further support for the fronto-striatal dysfunction model. Biol Psychiatry 2005; 58:239-244 (Pubitemid 41112273)
45. de Wit S, Barker RA, Dickinson T, Cools R: Habitual versus goal-directed action control in Parkinson's disease. J Cogn Neurosci 2010; 23:1218-1229
46. Clarke HF, Walker SC, Dalley JW, Robbins TW, Roberts AC: Cognitive inflexibility after prefrontal serotonin depletion is behaviorally and neurochemically specific. Cereb Cortex 2007; 17:18-27 (Pubitemid 44973891)
47. Nonkes LJ, Tomson K, Maertin A, Dederen J, Maes JH, Homberg J: Orbitofrontal cortex and amygdalar over-activity is associated with an inability to use the value of expected outcomes to guide behaviour in serotonin transporter knockout rats. Neurobiol Learn Mem 2010; 94:65-72