Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Eakins, R ^a   Walsh, J ^a   Randle, L ^b   Jenkins, R E ^a   Schuppe Koistinen, I ^c   Rowe, C ^a   Starkey Lewis, P ^a   Vasieva, O ^a   Prats, N ^d   Brillant, N ^a   Auli, M ^d   Bayliss, M ^a   Webb, S ^a   Rees, J A ^a   Kitteringham, N R ^a   Goldring, C E ^a   Park, B K ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^c Almirall S A R and D Centre ^*  (Spain)

^d ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2E1; PARACETAMOL; PROTEOME;

ADAPTATION; ANIMAL; C57BL MOUSE; DRUG EFFECTS; ENZYMOLOGY; LIVER; MALE; METABOLISM; PROTEOMICS; RAT; SIGNAL TRANSDUCTION;

ACETAMINOPHEN; ADAPTATION, PHYSIOLOGICAL; ANIMALS; CYTOCHROME P-450 CYP2E1; LIVER; MALE; MICE, INBRED C57BL; PROTEOME; PROTEOMICS; RATS; SIGNAL TRANSDUCTION;

EID: 84948435764     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep16423     Document Type: Article

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