Circadian regulation gene polymorphisms are associated with sleep disruption and duration, and circadian phase and rhythm in adults with HIV

Chronobiology International

Volumn 32, Issue 9, 2015, Pages 1278-1293

  Lee, Kathryn A ^a   Gay, Caryl ^a,b   Byun, Eeeseung ^a   Lerdal, Anners ^b,c   Pullinger, Clive R ^a   Aouizerat, Bradley E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LOVISENBERG DIAKONALE HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Acrophase; actigraphy; autocorrelation; chronotype; circadian; genetic; HIV; mesor

Indexed keywords

CIRCADIAN RHYTHM SIGNALING PROTEIN; CLOCK PROTEIN, HUMAN; CRY1 PROTEIN, HUMAN; CRYPTOCHROME; PER1 PROTEIN, HUMAN; PER2 PROTEIN, HUMAN; PER3 PROTEIN, HUMAN; TRANSCRIPTION FACTOR CLOCK;

ADULT; AGED; CALIFORNIA; COMPLICATION; FEMALE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; HABIT; HIV INFECTIONS; HUMAN; LONGITUDINAL STUDY; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PERIODICITY; PHENOTYPE; PSYCHOLOGY; RISK FACTOR; SLEEP; SLEEP DISORDER; TIME FACTOR; WAKEFULNESS; YOUNG ADULT;

ACTIVITY CYCLES; ADULT; AGED; CIRCADIAN RHYTHM SIGNALING PEPTIDES AND PROTEINS; CLOCK PROTEINS; CRYPTOCHROMES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HABITS; HIV INFECTIONS; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PERIOD CIRCADIAN PROTEINS; PHENOTYPE; POLYMORPHISM, GENETIC; RISK FACTORS; SAN FRANCISCO; SLEEP; SLEEP WAKE DISORDERS; TIME FACTORS; WAKEFULNESS; YOUNG ADULT;

EID: 84947908653     PISSN: 07420528     EISSN: 15256073     Source Type: Journal    
DOI: 10.3109/07420528.2015.1087021     Document Type: Article

References (59)

1. Allebrandt KV, Teder-Laving M, Akyol M, et al. (2010). CLOCK gene variants associate with sleep duration in two independent populations. Biol Psychiatry. 67:1040-7.
2. Ancoli-Israel S, Clopton P, Klauber MR, et al. (1997). Use of wrist activity for monitoring sleep/wake in demented nursing-home patients. Sleep. 20:24-7.
3. Aouizerat BE, Dodd M, Lee K, et al. (2009). Preliminary evidence of a genetic association between tumor necrosis factor alpha and the severity of sleep disturbance and morning fatigue. Biol Res Nurs. 11:27-41.
4. Barclay NL, Eley TC, Mill J, et al. (2011). Sleep quality and diurnal preference in a sample of young adults: Associations with 5HTTLPR, PER3, and CLOCK 3111. Am J Med Genet B Neuropsychiatr Genet. 156B:681-90.
5. Barrett JC, Fry B, Maller J, Daly MJ. (2005). Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics. 21: 263-5.
6. Blomeyer D, Buchmann AF, Lascorz J, et al. (2013). Association of PER2 genotype and stressful life events with alcohol drinking in young adults. PLoS One. 8:e59136.
7. Borbely AA. (1998). Processes underlying sleep regulation. Horm Res. 49:114-17.
8. Brower KJ, Wojnar M, Sliwerska E, et al. (2012). PER3 polymorphism and insomnia severity in alcohol dependence. Sleep. 35: 571-7.
9. Bunney BG, Li JZ, Walsh DM, et al. (2015). Circadian dysregulation of clock genes: Clues to rapid treatments in major depressive disorder. Mol Psychiatry. 20:48-55.
10. Buysse DJ, Reynolds CF III, Monk TH, et al. (1989). The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Res. 28:193-213.
11. Carpen JD, Archer SN, Skene DJ, et al. (2005). A single-nucleotide polymorphism in the 5′-untranslated region of the hPER2 gene is associated with diurnal preference. J Sleep Res. 14:293-7.
12. Carpen JD, von Schantz M, Smits M, et al. (2006). A silent polymorphism in the PER1 gene associates with extreme diurnal preference in humans. J Hum Genet. 51:1122-5.
13. Cole RJ, Kripke DF, Gruen W, et al. (1992). Automatic sleep/wake identification from wrist activity. Sleep. 15:461-9.
14. Comasco E, Nordquist N, Gokturk C, et al. (2010). The clock gene PER2 and sleep problems: Association with alcohol consumption among Swedish adolescents. Ups J Med Sci. 115:41-8.
15. Daan S, Beersma DG, Borbely AA. (1984). Timing of human sleep: Recovery process gated by a circadian pacemaker. Am J Physiol. 246:R161-83.
16. Dunlap JC. (1999). Molecular bases for circadian clocks. Cell. 96: 271-90.
17. Forbes EE, Dahl RE, Almeida JR, et al. (2012). PER2 rs2304672 polymorphism moderates circadian-relevant reward circuitry activity in adolescents. Biol Psychiatry. 71:451-7.
18. Gamaldo CE, Gamaldo A, Creighton J, et al. (2013a). Evaluating sleep and cognition in HIV. J Acquir Immune Defic Syndr. 63: 609-16.
19. Gamaldo CE, Spira AP, Hock RS, et al. (2013b). Sleep, function and HIV: A multi-method assessment. AIDS Behav. 17:2808-15.
20. Gekakis N, Staknis D, Nguyen HB, et al. (1998). Role of the CLOCK protein in the mammalian circadian mechanism. Science. 280: 1564-9.
21. Halder I, Matthews K, Buysse D, et al. (2015). African genetic ancestry is associated with sleep depth in older African Americans. Sleep. 38:1185-93.
22. Halder I, Shriver M, Thomas M, et al. (2008). A panel of ancestry informative markers for estimating individual biogeographical ancestry and admixture from four continents: Utility and applications. Hum Mutat. 29:648-58.
23. Haus E, Smolensky MH. (1999). Biologic rhythms in the immune system. Chronobiol Int. 16:581-622.
24. Hida A, Kitamura S, Katayose Y, et al. (2014). Screening of clock gene polymorphisms demonstrates association of a PER3 polymorphism with morningness-eveningness preference and circadian rhythm sleep disorder. Sci Rep. 4:6309.
25. Hoggart CJ, Parra EJ, Shriver MD, et al. (2003). Control of confounding of genetic associations in stratified populations. Am J Hum Genet. 72:1492-504.
26. Horne JA, Ostberg O. (1976). A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. Int J Chronobiol. 4:97-110.
27. Hua P, Liu W, Chen D, et al. (2014). Cry1 and Tef gene polymorphisms are associated with major depressive disorder in the Chinese population. J Affect Disord. 157:100-3.
28. Katzenberg D, Young T, Finn L, et al. (1998). A CLOCK polymorphism associated with human diurnal preference. Sleep. 21: 569-76.
29. Kishi T, Kitajima T, Ikeda M, et al. (2009). CLOCK may predict the response to fluvoxamine treatment in Japanese major depressive disorder patients. Neuromolecular Med. 11:53-7.
30. Ko CH, Takahashi JS. (2006). Molecular components of the mammalian circadian clock. Hum Mol Genet. 15 Spec No 2: R271-7.
31. Konig R, Zhou Y, Elleder D, et al. (2008). Global analysis of hostpathogen interactions that regulate early-stage HIV-1 replication. Cell. 135:49-60.
32. Lavebratt C, Sjoholm LK, Partonen T, et al. (2010). PER2 variantion is associated with depression vulnerability. Am J Med Genet B Neuropsychiatr Genet. 153B:570-81.
33. Lee HJ, Kim L, Kang SG, et al. (2011). PER2 variation is associated with diurnal preference in a Korean young population. Behav Genet. 41:273-7.
34. Lee KA, Gay C, Portillo CJ, et al. (2009). Symptom experience in HIV-infected adults: A function of demographic and clinical characteristics. J Pain Symptom Manage. 38:882-93.
35. Lee KA, Gay C, Portillo CJ, et al. (2012). Types of sleep problems in adults living with HIV/AIDS. J Clin Sleep Med. 8:67-75.
36. Lichstein KL, Stone KC, Donaldson J, et al. (2006). Actigraphy validation with insomnia. Sleep. 29:232-9.
37. Lincoln GA, Andersson H, Loudon A. (2003). Clock genes in calendar cells as the basis of annual timekeeping in mammals - a unifying hypothesis. J Endocrinol. 179:1-13.
38. Liu JJ, Sudic Hukic D, Forsell Y, et al. (2015). Depression-associated ARNTL and PER2 genetic variants in psychotic disorders. Chronobiol Int. 32:579-84.
39. Nicholas B, Rudrasingham V, Nash S, et al. (2007). Association of Per1 and Npas2 with autistic disorder: Support for the clock genes/social timing hypothesis. Mol Psychiatry. 12:581-92.
40. Ojeda DA, Perea CS, Nino CL, et al. (2013). A novel association of two non-synonymous polymorphisms in PER2 and PER3 genes with specific diurnal preference subscales. Neurosci Lett. 553: 52-6.
41. Osland TM, Bjorvatn BR, Steen VM, Pallesen S. (2011). Association study of a variable-number tandem repeat polymorphism in the clock gene PERIOD3 and chronotype in Norwegian university students. Chronobiol Int. 28:764-70.
42. Parsons MJ, Lester KJ, Barclay NL, et al. (2014). Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNbeta3 with sleep measures. J Sleep Res. 23:595-604.
43. Phillips KD, Sowell RL, Boyd M, et al. (2005). Sleep quality and health-related quality of life in HIV-infected African-American women of childbearing age. Qual Life Res. 14:959-70.
44. Price AL, Patterson NJ, Plenge RM, et al. (2006). Principal components analysis corrects for stratification in genomewide association studies. Nat Genet. 38:904-9.
45. Radloff LS. (1977). The CES-D scale: A self-report depression scale for research in the general population. Appl Psych Meas. 1: 385-401.
46. Rubinstein ML, Selwyn PA. (1998). High prevalence of insomnia in an outpatient population with HIV infection. J Acquir Immune Defic Syndr Hum Retrovirol. 19:260-5.
47. Serretti A, Cusin C, Benedetti F, et al. (2005). Insomnia improvement during antidepressant treatment and CLOCK gene polymorphism. Am J Med Genet B Neuropsychiatr Genet. 137B: 36-9.
48. Serretti A, Gaspar-Barba E, Calati R, et al. (2010). 3111T/C clock gene polymorphism is not associated with sleep disturbances in untreated depressed patients. Chronobiol Int. 27:265-77.
49. Shearman LP, Sriram S, Weaver DR, et al. (2000). Interacting molecular loops in the mammalian circadian clock. Science. 288:1013-19.
50. Shi J, Wittke-Thompson JK, Badner JA, et al. (2008). Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm. Am J Med Genet B Neuropsychiatr Genet. 147B:1047-55.
51. Shumay E, Fowler JS, Wang GJ, et al. (2012). Repeat variation in the human PER2 gene as a new genetic marker associated with cocaine addiction and brain dopamine D2 receptor availability. Transl Psychiatry. 2:e86.
52. Taibi DM, Price C, Voss J. (2013). A pilot study of sleep quality and rest-activity patterns in persons living with HIV. J Assoc Nurses AIDS Care. 24:411-21.
53. Takahashi JS, Hong HK, Ko CH, McDearmon EL. (2008). The genetics of mammalian circadian order and disorder: Implications for physiology and disease. Nat Rev Genet. 9: 764-75.
54. Tian C, Gregersen PK, Seldin MF. (2008). Accounting for ancestry: Population substructure and genome-wide association studies. Hum Mol Genet. 17:R143-50.
55. Weger BD, Sahinbas M, Otto GW, et al. (2011). The light responsive transcriptome of the zebrafish: Function and regulation. PLoS One. 6:e17080.
56. Zhang L, Ptacek LJ, Fu YH. (2013). Diversity of human clock genotypes and consequences. Prog Mol Biol Transl Sci. 119: 51-81.
57. Zhao B, Lu J, Yin J, et al. (2012). A functional polymorphism in PER3 gene is associated with prognosis in hepatocellular carcinoma. Liver Int. 32:1451-9.
58. Zhu Y, Stevens RG, Hoffman AE, et al. (2009). Testing the circadian gene hypothesis in prostate cancer: A population-based casecontrol study. Cancer Res. 69:9315-22.
59. Ziv-Gal A, Flaws JA, Mahoney MM, et al. (2013). Genetic polymorphisms in the aryl hydrocarbon receptor-signaling pathway and sleep disturbances in middle-aged women. Sleep Med. 14: 883-7.