PER2 rs2304672 polymorphism moderates circadian-relevant reward circuitry activity in adolescents

Biological Psychiatry

Volumn 71, Issue 5, 2012, Pages 451-457

  Forbes, Erika E ^a,b   Dahl, Ronald E ^d   Almeida, Jorge R C ^a   Ferrell, Robert E ^c   Nimgaonkar, Vishwajit L ^a   Mansour, Hader ^a   Sciarrillo, Samantha R ^a   Holm, Stephanie M ^a   Rodriguez, Eric E ^a   Phillips, Mary L ^a,e  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Brain function; circadian function; clock pathway genes; development; PER2; reward

Indexed keywords

PER2 PROTEIN;

ACTIMETRY; ADOLESCENT; ALLELE; ARTICLE; BLOOD OXYGENATION; CHILD; CIRCADIAN RHYTHM; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENOTYPE; HOMOZYGOTE; HUMAN; MALE; NERVE CELL MEMBRANE POTENTIAL; NORMAL HUMAN; PREDICTIVE VALUE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PUBERTY; REWARD; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; TASK PERFORMANCE;

ACTIGRAPHY; ADOLESCENT; ADOLESCENT BEHAVIOR; ALLELES; CHILD; CIRCADIAN RHYTHM; FEMALE; FUNCTIONAL NEUROIMAGING; GENOTYPE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PERIOD CIRCADIAN PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREFRONTAL CORTEX; PSYCHOMOTOR PERFORMANCE; REWARD; SLEEP;

EID: 84858752741     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.10.012     Document Type: Article

References (38)

1. E.E. Forbes Where's the fun in that? Broadening the focus on reward function in depression Biol Psychiatry 66 2009 199 200
2. M.L. Phillips, C.D. Ladouceur, W.C. Drevets A neural model of voluntary and automatic emotion regulation: Implications for understanding the pathophysiology and neurodevelopment of bipolar disorder Biol Psychiatry 13 2008 833 857 829
3. G.F. Koob, M. Le Moal Neurobiological mechanisms for opponent motivational processes in addiction Phil Trans R Society Lond Ser B Biol Sci 363 2008 3113 3123
4. T.E. Robinson, K.C. Berridge The psychology and neurobiology of addiction: An incentive-sensitization view Addiction 95 suppl 2 2000 S91 S117
5. E.C. Dowd, D.M. Barch Anhedonia and emotional experience in schizophrenia: neural and behavioral indicators Biol Psychiatry 67 2010 902 911
6. C.A. McClung Circadian genes, rhythms and the biology of mood disorder Pharmacol Ther 114 2007 222 232 (Pubitemid 46561535)
7. R. Benca, M.J. Duncan, E. Frank, C. McClung, R.J. Nelson, A. Vicentic Biological rhythms, higher brain function, and behavior: Gaps, opportunities, and challenges Brain Res Rev 62 2009 57 70
8. H.A. Mansour, T.H. Monk, V.L. Nimgaonkar Circadian genes and bipolar disorder Ann Med 37 2005 196 205 (Pubitemid 40780437)
9. B.P. Hasler, J.J. Allen, D.A. Sbarra, R.R. Bootzin, R.A. Bernert Morningness-eveningness and depression: Preliminary evidence for the role of the behavioral activation system and positive affect Psychiatry Res 176 2010 166 173
10. A. Adan, J. Lachica, H. Caci, V. Natale Circadian typology and temperament and character personality dimensions Chronobiol Int 27 2010 181 193
11. R. Andretic, S. Chaney, J. Hirsh Requirement of circadian genes for cocaine sensitization in Drosophila Science 285 1999 1066 1068
12. C.A. McClung, K. Sidiropoulou, M. Vitaterna, J.S. Takahashi, F.J. White, D.C. Cooper Regulation of dopaminergic transmission and cocaine reward by the Clock gene Proc Natl Acad Sci U S A 102 2005 9377 9381 (Pubitemid 40923571)
13. K. Roybal, D. Theobold, A. Graham, J.A. DiNieri, S.J. Russo, V. Krishnan Mania-like behavior induced by disruption of CLOCK Proc Natl Acad Sci U S A 104 2007 6406 6411 (Pubitemid 47186107)
14. S. Amir, J. Stewart Motivational modulation of rhythms of the expression of the clock protein PER2 in the limbic forebrain Biol Psychiatry 65 2009 829 834
15. K. Bae, X. Jin, E.S. Maywood, M.H. Hastings, S.M. Reppert, D.R. Weaver Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock Neuron 30 2001 525 536 (Pubitemid 32530594)
16. C. Abarca, U. Albrecht, R. Spanagel Cocaine sensitization and reward are under the influence of circadian genes and rhythm Proc Natl Acad Sci U S A 99 2002 9026 9030 (Pubitemid 34693677)
17. R. Spanagel, G. Pendyala, C. Abarca, T. Zghoul, C. Sanchis-Segura, M.C. Magnone The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption Nat Med 11 2005 35 42 (Pubitemid 40215835)
18. E.J. Nestler, W.A. Carlezon Jr The mesolimbic dopamine reward circuit in depression Biol Psychiatry 59 2006 1151 1159 (Pubitemid 44192421)
19. D.A. Pizzagalli, A.J. Holmes, D.G. Dillon, E.L. Goetz, J.L. Birk, R. Bogdan Reduced caudate and nucleus accumbens response to rewards in unmedicated individuals with major depressive disorder Am J Psychiatry 166 2009 702 710
20. E.E. Forbes, A.R. Hariri, S.L. Martin, J.S. Silk, D.L. Moyles, P.M. Fisher Altered striatal activation predicting real-world positive affect in adolescent major depressive disorder Am J Psychiatry 166 2009 64 73
21. H.A. Mansour, M.E. Talkowski, J. Wood, K.V. Chowdari, L. McClain, K. Prasad Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia Bipolar Disord 11 2009 701 710
22. R.C. Kessler, G.P. Amminger, S. Aguilar-Gaxiola, J. Alonso, S. Lee, T.B. Ustun Age of onset of mental disorders: A review of recent literature Curr Opin Psychiatry 20 2007 359 364 (Pubitemid 46889663)
23. E.E. Forbes, N.D. Ryan, M.L. Phillips, S.B. Manuck, C.M. Worthman, D.L. Moyles Healthy adolescents' neural response to reward: Associations with puberty, positive affect, and depressive symptoms J Am Acad Child Adolesc Psychiatry 49 2010 162 172
24. S.J. Crowley, C. Acebo, M.A. Carskadon Sleep, circadian rhythms, and delayed phase in adolescence Sleep Med 8 2007 602 612 (Pubitemid 47181210)
25. M.E. Herman-Giddens, E.J. Slora, R.C. Wasserman, C.J. Bourdony, M.V. Bhapkar, G.G. Koch Secondary sexual characteristics and menses in young girls seen in office practice: a study from the Research in Office Settings network Pediatrics 99 1997 505 512
26. A.M. Karpati, C.H. Rubin, S.M. Kieszak, M. Marcus, R.P. Troiano Pubertal stage assessment in American boys: The 19881994 Third National Health and Nutrition Examination Survey Adolesc Health 30 2002 205 212 (Pubitemid 34175146)
27. W.A. Marshall, J.M. Tanner Growth and physiological development during adolescence Annu Rev Med 19 1968 283 300
28. A. Angold, A. Erkanli, J. Silberg, L. Eaves, E.J. Costello Depression scale scores in 817-year-olds: Effects of age and gender J Child Psychol Psychiatry 43 2002 1052 1063 (Pubitemid 36939281)
29. International HapMap Project (n.d.): www.hapmap.org.
30. E.E. Forbes, S.M. Brown, M. Kimak, R.E. Ferrell, S.B. Manuck, A.R. Hariri Genetic variation in components of dopamine neurotransmission impacts ventral striatal reactivity associated with impulsivity Mol Psychiatry 14 2009 60 70
31. R.J. Cole, D.F. Kripke, W. Gruen, D.J. Mullaney, J.C. Gillin Automatic sleep/wake identification from wrist activity Sleep 15 1992 461 469
32. H.J. Burgess, N. Savic, T. Sletten, G. Roach, S.S. Gilbert, D. Dawson The relationship between the dim light melatonin onset and sleep on a regular schedule in young healthy adults Behav Sleep Med 1 2003 102 114
33. H. Wang, C.A. Haiman, L.N. Kolonel, B.E. Henderson, L.R. Wilkens, L. Le Marchand Self-reported ethnicity, genetic structure and the impact of population stratification in a multiethnic study Hum Genet 128 2010 165 177
34. M. Garaulet, M.D. Corbalan-Tutau, J.A. Madrid, J.C. Baraza, L.D. Parnell, Y.C. Lee PERIOD2 variants are associated with abdominal obesity, psycho-behavioral factors, and attrition in the dietary treatment of obesity J Am Diet Assoc 110 2010 917 921
35. F. Benedetti, D. Radaelli, A. Bernasconi, S. Dallaspezia, A. Falini, G. Scotti Clock genes beyond the clock: CLOCK genotype biases neural correlates of moral valence decision in depressed patients Genes Brain Behav 7 2008 20 25
36. S.N. Haber, B. Knutson The reward circuit: Linking primate anatomy and human imaging Neuropsychopharmacology 35 2010 4 26
37. D.M. Amodio, C.D. Frith Meeting of minds: The medial frontal cortex and social cognition Nat Rev Neurosci 7 2006 268 277
38. S.M. Holm, E.E. Forbes, N.D. Ryan, M.L. Phillips, J.A. Tarr, R.E. Dahl Reward-related brain function and sleep in pre/early pubertal and mid/late pubertal adolescents J Adolesc Health 45 2009 326 334