Depression-associated ARNTL and PER2 genetic variants in psychotic disorders

Chronobiology International

Volumn 32, Issue 4, 2015, Pages 579-584

  Liu, Jia J ^a,b   Sudic Hukic, Dzana ^b,c   Forsell, Yvonne ^b   Schalling, Martin ^b,c   Ösby, Urban ^b,c,d   Lavebratt, Catharina ^b,c  

^a SHANDONG UNIVERSITY   (China)

^b KAROLINSKA INSTITUTE   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d Department of Psychiatry Tiohundra Hospital   (Sweden)

Author keywords

ARNTL; Circadian; CRY2; PER2; Psychosis; Severity

Indexed keywords

ARNTL PROTEIN, HUMAN; CIRCADIAN RHYTHM SIGNALING PROTEIN; PER2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK;

ADULT; AGED; CIRCADIAN RHYTHM; DEPRESSION; FEMALE; GENETIC VARIATION; GENETICS; GENOTYPE; HUMAN; MAJOR DEPRESSION; MALE; MIDDLE AGED; PHYSIOLOGY; PSYCHOSIS; SINGLE NUCLEOTIDE POLYMORPHISM; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ARNTL TRANSCRIPTION FACTORS; CIRCADIAN RHYTHM; CLOCK PROTEINS; DEPRESSION; DEPRESSIVE DISORDER, MAJOR; FEMALE; GENETIC VARIATION; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PERIOD CIRCADIAN PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PSYCHOTIC DISORDERS; YOUNG ADULT;

EID: 84928896209     PISSN: 07420528     EISSN: 15256073     Source Type: Journal    
DOI: 10.3109/07420528.2015.1012588     Document Type: Article

References (39)

1. Byrne EM, Heath AC, Madden PA, et al. (2014). Testing the role of circadian genes in conferring risk for psychiatric disorders. Am J Med Genet B Neuropsychiatr Genet. 165B:254-60.
2. Børglum A, Demontis D, Grove J, et al. (2014). Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci. Mol Psychiatry. 19: 325-33.
3. Cardno AG, Gottesman II. (2000). Twin studies of schizophrenia: from bow-and-arrow concordances to star wars Mx and functional genomics. Am J Med Genet. 97:12-17.
4. Chen R, Schirmer A, Lee Y, et al. (2009). Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism. Mol Cell. 36:417-30.
5. Chong S, Ptác?ek LJ, Fu Y-H. (2012). Genetic insights on sleep schedules: This time, it's PERsonal. Trends Genet. 28: 598-605.
6. Etain B, Milhiet V, Bellivier F, Leboyer M. (2011). Genetics of circadian rhythms and mood spectrum disorders. Eur Neuropsychopharmacol. 21:S676-82.
7. Gao X, Starmer J, Martin ER. (2008). A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms. Genet Epidemiol. 32:361-9.
8. Germain A, Kupfer DJ. (2008). Circadian rhythm disturbances in depression. Hum Psychopharmacol. 23:571-85.
9. Hafner H, Maurer K, Trendler G, et al. (2005a). Schizophrenia and depression: Challenging the paradigm of two separate diseases-A controlled study of schizophrenia, depression and healthy controls. Schizophr Res. 77:11-24.
10. Hafner H, Maurer K, Trendler G, et al. (2005b). The early course of schizophrenia and depression. Eur Arch Psychiatry Clin Neurosci. 255:167-73.
11. Humphreys K, Grankvist A, Leu M, et al. (2011). The genetic structure of the Swedish population. PLoS One. 6: e22547.
12. Johansson C, Willeit M, Smedh C, et al. (2003). Circadian clockrelated polymorphisms in seasonal affective disorder and their relevance to diurnal preference. Neuropsychopharmacology. 28:734-9.
13. Koreen AR, Sins SG, Chakos M. (1993). Depression in first-episode schizophrenia. Am J Psychiatry. 150:1643-8.
14. Kornmann B, Schaad O, Bujard H, et al. (2007). System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock. PLoS Biol. 5:e34.
15. Kripke DF, Nievergelt CM, Joo E, et al. (2009). Circadian polymorphisms associated with affective disorders. J Circadian Rhythms. 7:2.
16. Lamont EW, Coutu DL, Cermakian N, Boivin DB. (2009). Circadian rhythms and clock genes in psychotic disorders. Isr J Psychiatry Relat Sci. 47:27-35.
17. Lappalainen T, Hannelius U, Salmela E, et al. (2009). Population structure in contemporary Sweden-A Y-chromosomal and mitochondrial DNA analysis. Annals Human Genet. 73:61-73.
18. Lavebratt C, Sjoholm LK, Partonen T, et al. (2010a). PER2 variantion is associated with depression vulnerability. Am J Med Genet B Neuropsychiatr Genet. 153B:570-81.
19. Lavebratt C, Sjöholm LK, Soronen P, et al. (2010b). CRY2 is associated with depression. PLoS One. 5:e9407.
20. Le-Niculescu H, Patel SD, Bhat M, et al. (2009). Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms. Am J Med Genet B Neuropsychiatr Genet. 150B:155-81.
21. Lichtenstein P, Yip BH, Bjork C, et al. (2009). Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study. Lancet. 373:234-9.
22. Lundberg I, Damstrom Thakker K, et al. (2005). Determinants of non-participation, and the effects of non-participation on potential cause-effect relationships, in the PART study on mental disorders. Soc Psychiatry Psychiatr Epidemiol. 40: 475-83.
23. Mansour H, Wood J, Logue T, et al. (2006). Association study of eight circadian genes with bipolar I disorder, schizoaffective disorder and schizophrenia. Genes Brain Behav. 5:150-7.
24. Mansour HA, Talkowski ME, Wood J, et al. (2009). Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia. Bipolar Disord. 11: 701-10.
25. McCarthy MJ, Nievergelt CM, Kelsoe JR, Welsh DK. (2012). A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response. PLoS One. 7:e32091.
26. Nyholt DR. (2004). A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Human Genet. 74:765-9.
27. Ogden CA, Rich ME, Schork NJ, et al. (2004). Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: An expanded convergent functional genomics approach. Mol Psychiatry. 9:1007-29.
28. Otowa T, Tochigi M, Kawamura Y, et al. (2011). An association analysis of Per2 with panic disorder in the Japanese population. J Human Genet. 56:748-50.
29. Partonen T. (2012). Clock gene variants in mood and anxiety disorders. J Neural Transm. 119:1133-45.
30. Partonen T, Treutlein J, Alpman A, et al. (2007). Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression. Ann Med. 39:229-38.
31. Portaluppi F, Smolensky MH, Touitou Y. (2010). Ethics and methods for biological rhythm research on animals and human beings. Chronobiol Int. 27:1911-29.
32. Reppert SM, Weaver DR. (2002). Coordination of circadian timing in mammals. Nature. 418:935-41.
33. Ripke S, O'Dushlaine C, Chambert K, et al. (2013). Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet. 45:1150-9.
34. Siris SG, Bench C. (2003). Depression and schizophrenia. In Hirsch SR, Weinberger DR, eds. Schizophrenia. Oxford: Blackwell Publishing, pp. 142-67.
35. Sjöholm LK, Backlund L, Cheteh EH, et al. (2010). CRY2 is associated with rapid cycling in bipolar disorder patients. PLoS One. 5:e12632.
36. Soria V, Martinez-Amoros E, Escaramis G, et al. (2010). Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder. Neuropsychopharmacology. 35:1279-89.
37. Sullivan PF, Kendler KS, Neale MC. (2003). Schizophrenia as a complex trait: Evidence from a meta-analysis of twin studies. Arch Gen Psychiatry. 60:1187-92.
38. Utge SJ, Soronen P, Loukola A, et al. (2010). Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance. PLoS One. 5:e9259.
39. Wulff K, Gatti S, Wettstein JG, Foster RG. (2010). Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease. Nat Rev Neurosci. 11:589-99.