-
1
-
-
78851468865
-
The economic burden of obesity worldwide: A systematic review of the direct costs of obesity
-
Withrow D and Alter DA. The economic burden of obesity worldwide: a systematic review of the direct costs of obesity. Obes Rev 2011; 12: 131-141.
-
(2011)
Obes Rev
, vol.12
, pp. 131-141
-
-
Withrow, D.1
Alter, D.A.2
-
2
-
-
84862776702
-
A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
Bostrom P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Bostrom EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Hojlund K, Gygi SP and Spiegelman BM. A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012; 481: 463-468.
-
(2012)
Nature
, vol.481
, pp. 463-468
-
-
Bostrom, P.1
Wu, J.2
Jedrychowski, M.P.3
Korde, A.4
Ye, L.5
Lo, J.C.6
Rasbach, K.A.7
Bostrom, E.A.8
Choi, J.H.9
Long, J.Z.10
Kajimura, S.11
Zingaretti, M.C.12
Vind, B.F.13
Tu, H.14
Cinti, S.15
Hojlund, K.16
Gygi, S.P.17
Spiegelman, B.M.18
-
3
-
-
84876133911
-
FNDC5/irisin is not only a myokine but also an adipokine
-
Roca-Rivada A, Castelao C, Senin LL, Landrove MO, Baltar J, Belén Crujeiras A, Seoane LM, Casanueva FF and Pardo M. FNDC5/irisin is not only a myokine but also an adipokine. PLoS One 2013; 8: e60563.
-
(2013)
Plos One
, vol.8
-
-
Roca-Rivada, A.1
Castelao, C.2
Senin, L.L.3
Landrove, M.O.4
Baltar, J.5
Belén Crujeiras, A.6
Seoane, L.M.7
Casanueva, F.F.8
Pardo, M.9
-
4
-
-
84894278954
-
Longitudinal variation of circulating irisin after an energy restriction-induced weight loss and following weight regain in obese men and women
-
Crujeiras AB, Pardo M, Arturo RR, Navas-Carretero S, Zulet MA, Martinez JA and Casanueva FF. Longitudinal variation of circulating irisin after an energy restriction-induced weight loss and following weight regain in obese men and women. Am J Hum Biol 2014; 26: 198-207.
-
(2014)
Am J Hum Biol
, vol.26
, pp. 198-207
-
-
Crujeiras, A.B.1
Pardo, M.2
Arturo, R.R.3
Navas-Carretero, S.4
Zulet, M.A.5
Martinez, J.A.6
Casanueva, F.F.7
-
5
-
-
84919487162
-
High circulating irisin levels are associated with insulin resistance and vascular atherosclerosis in a cohort of nondiabetic adult subjects
-
Sesti G, Andreozzi F, Fiorentino TV, Mannino GC, Sciacqua A, Marini MA and Perticone F. High circulating irisin levels are associated with insulin resistance and vascular atherosclerosis in a cohort of nondiabetic adult subjects. Acta Diabetol 2014; 51: 705-713.
-
(2014)
Acta Diabetol
, vol.51
, pp. 705-713
-
-
Sesti, G.1
Reozzi, F.2
Fiorentino, T.V.3
Mannino, G.C.4
Sciacqua, A.5
Marini, M.A.6
Perticone, F.7
-
6
-
-
84882890178
-
Irisin is inversely associated with intrahepatic triglyceride contents in obese adults
-
Zhang HJ, Zhang XF, Ma ZM, Pan LL, Chen Z, Han HW, Han CK, Zhuang XJ, Lu Y, Li XJ, Yang SY and Li XY. Irisin is inversely associated with intrahepatic triglyceride contents in obese adults. J Hepatol 2013; 59: 557-562.
-
(2013)
J Hepatol
, vol.59
, pp. 557-562
-
-
Zhang, H.J.1
Zhang, X.F.2
Ma, Z.M.3
Pan, L.L.4
Chen, Z.5
Han, H.W.6
Han, C.K.7
Zhuang, X.J.8
Lu, Y.9
Li, X.J.10
Yang, S.Y.11
Li, X.Y.12
-
7
-
-
84877129604
-
Decrease in irisin in patients with chronic kidney disease
-
Wen MS, Wang CY, Lin SL and Hung KC. Decrease in irisin in patients with chronic kidney disease. PLoS One 2013; 8: e64025.
-
(2013)
Plos One
, vol.8
-
-
Wen, M.S.1
Wang, C.Y.2
Lin, S.L.3
Hung, K.C.4
-
8
-
-
84908305311
-
Irisin promotes human umbilical vein endothelial cell proliferation through the ERK signaling pathway and partly suppresses high glucose-induced apoptosis
-
Song H, Wu F, Zhang Y, Zhang Y, Wang F, Jiang M, Wang Z, Zhang M, Li S, Yang L, Wang XL, Cui T and Tang D. Irisin promotes human umbilical vein endothelial cell proliferation through the ERK signaling pathway and partly suppresses high glucose-induced apoptosis. PLoS One 2014; 9: e110273-e110273.
-
(2014)
Plos One
, vol.9
-
-
Song, H.1
Wu, F.2
Zhang, Y.3
Zhang, Y.4
Wang, F.5
Jiang, M.6
Wang, Z.7
Zhang, M.8
Li, S.9
Yang, L.10
Wang, X.L.11
Cui, T.12
Tang, D.13
-
9
-
-
84865314974
-
Irisin: A new potential hormonal target for the treatment of obesity and type 2 diabetes
-
Sanchis-Gomar F, Lippi G, Mayero S, Perez-Quilis C and Garcia-Gimenez JL. Irisin: a new potential hormonal target for the treatment of obesity and type 2 diabetes. J Diabetes 2012; 4: 196.
-
(2012)
J Diabetes
, vol.4
, pp. 196
-
-
Sanchis-Gomar, F.1
Lippi, G.2
Mayero, S.3
Perez-Quilis, C.4
Garcia-Gimenez, J.L.5
-
10
-
-
84876222786
-
Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance
-
Moreno-Navarrete JM, Ortega F, Serrano M, Guerra E, Pardo G, Tinahones F, Ricart W and Fernandez-Real JM. Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance. J Clin Endocrinol Metab 2013; 98: E769-778.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, pp. E769-E778
-
-
Moreno-Navarrete, J.M.1
Ortega, F.2
Serrano, M.3
Guerra, E.4
Pardo, G.5
Tinahones, F.6
Ricart, W.7
Fernandez-Real, J.M.8
-
11
-
-
84878753448
-
Metformin revisited: A critical review of the benefit-risk balance in at-risk patients with type 2 diabetes
-
Scheen AJ and Paquot N. Metformin revisited: a critical review of the benefit-risk balance in at-risk patients with type 2 diabetes. Diabetes Metab 2013; 39: 179-190.
-
(2013)
Diabetes Metab
, vol.39
, pp. 179-190
-
-
Scheen, A.J.1
Paquot, N.2
-
12
-
-
84921447098
-
Metformin promotes irisin release from murine skeletal muscle independently of AMP-activated protein kinase activation
-
Li DJ, Huang F, Lu WJ, Jiang GJ, Deng YP and Shen FM. Metformin promotes irisin release from murine skeletal muscle independently of AMP-activated protein kinase activation. Acta Physiol (Oxf) 2015; 213: 711-21.
-
(2015)
Acta Physiol (Oxf)
, vol.213
, pp. 711-721
-
-
Li, D.J.1
Huang, F.2
Lu, W.J.3
Jiang, G.J.4
Deng, Y.P.5
Shen, F.M.6
-
13
-
-
84908637057
-
NT-PGC-1α activation attenuates high-fat diet-induced obesity by enhancing brown fat thermogenesis and adipose tissue oxidative metabolism
-
Jun HJ, Joshi Y, Patil Y, Noland RC and Chang JS. NT-PGC-1α activation attenuates high-fat diet-induced obesity by enhancing brown fat thermogenesis and adipose tissue oxidative metabolism. Diabetes 2014; 63: 3615-3625.
-
(2014)
Diabetes
, vol.63
, pp. 3615-3625
-
-
Jun, H.J.1
Joshi, Y.2
Patil, Y.3
Noland, R.C.4
Chang, J.S.5
-
14
-
-
84921409082
-
Association between irisin and homocysteine in euglycemic and diabetic subjects
-
Alis R, Sanchis-Gomar F, Pareja-Galeano H, Hernández-Mijares A, Romagnoli M, Víctor VM and Rocha M. Association between irisin and homocysteine in euglycemic and diabetic subjects. Clin Biochem 2014; 47: 333-5.
-
(2014)
Clin Biochem
, vol.47
, pp. 333-335
-
-
Alis, R.1
Sanchis-Gomar, F.2
Pareja-Galeano, H.3
Hernández-Mijares, A.4
Romagnoli, M.5
Víctor, V.M.6
Rocha, M.7
-
15
-
-
84876736157
-
Serum irisin levels in new-onset type 2 diabetes
-
Choi YK, Kim MK, Bae KH, Seo HA, Jeong JY, Lee WK, Kim JG, Lee IK and Park KG. Serum irisin levels in new-onset type 2 diabetes. Diabetes Res Clin Pract 2013; 100: 96-101.
-
(2013)
Diabetes Res Clin Pract
, vol.100
, pp. 96-101
-
-
Choi, Y.K.1
Kim, M.K.2
Bae, K.H.3
Seo, H.A.4
Jeong, J.Y.5
Lee, W.K.6
Kim, J.G.7
Lee, I.K.8
Park, K.G.9
-
16
-
-
84897465484
-
Exercise-mimicking treatment fails to increase Fndc5 mRNA & irisin secretion in primary human myotubes
-
Kurdiova T, Balaz M, Mayer A, Maderova D, Belan V, Wolfrum C, Ukropec J and Ukropcova B. Exercise-mimicking treatment fails to increase Fndc5 mRNA & irisin secretion in primary human myotubes. Peptides 2014; 56: 1-7.
-
(2014)
Peptides
, vol.56
, pp. 1-7
-
-
Kurdiova, T.1
Balaz, M.2
Mayer, A.3
Maderova, D.4
Belan, V.5
Wolfrum, C.6
Ukropec, J.7
Ukropcova, B.8
-
17
-
-
84896493706
-
Common single nucleotide polymorphisms in the FNDC5 geneare associated with glucose metabolism but do not affect serum irisin levels in Japanese men with low fitness levels
-
Tanisawa K, Taniguchi H, Sun X, Ito T, Cao ZB, Sakamoto S and Higuchi M. Common single nucleotide polymorphisms in the FNDC5 geneare associated with glucose metabolism but do not affect serum irisin levels in Japanese men with low fitness levels. Metabolism 2014; 63: 574-583.
-
(2014)
Metabolism
, vol.63
, pp. 574-583
-
-
Tanisawa, K.1
Taniguchi, H.2
Sun, X.3
Ito, T.4
Cao, Z.B.5
Sakamoto, S.6
Higuchi, M.7
-
18
-
-
47949104798
-
The role of exercise and PGC1alpha in inflammation and chronic disease
-
Handschin C and Spiegelman BM. The role of exercise and PGC1alpha in inflammation and chronic disease. Nature 2008; 454: 463-469.
-
(2008)
Nature
, vol.454
, pp. 463-469
-
-
Handschin, C.1
Spiegelman, B.M.2
-
19
-
-
0038587678
-
PPARgamma coactivator-1alpha expression during thyroid hormone-and contractile activity-induced mitochondrial adaptations
-
Irrcher I, Adhihetty PJ, Sheehan T, Joseph AM and Hood DA. PPARgamma coactivator-1alpha expression during thyroid hormone-and contractile activity-induced mitochondrial adaptations. Am J Physiol Cell Physiol 2003; 284: C1669-C1677.
-
(2003)
Am J Physiol Cell Physiol
, vol.284
, pp. C1669-C1677
-
-
Irrcher, I.1
Adhihetty, P.J.2
Sheehan, T.3
Joseph, A.M.4
Hood, D.A.5
-
20
-
-
84895878715
-
Activation of AMP-activated protein kinase by metformin protects against global cerebral ischemia in male rats: Interference of AMPK/PGC-1alpha pathway
-
Ashabi G, Khodagholi F, Khalaj L, Goudarzvand M and Nasiri M. Activation of AMP-activated protein kinase by metformin protects against global cerebral ischemia in male rats: interference of AMPK/PGC-1alpha pathway. Metab Brain Dis 2014; 29: 47-58.
-
(2014)
Metab Brain Dis
, vol.29
, pp. 47-58
-
-
Ashabi, G.1
Khodagholi, F.2
Khalaj, L.3
Goudarzvand, M.4
Nasiri, M.5
-
21
-
-
33646828975
-
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alphasubunits in heart via hierarchical phosphorylation of Ser485/491
-
Horman S, Vertommen D, Heath R, Neumann D, Mouton V, Woods A, Schlattner U, Wallimann T, Carling D, Hue L and Rider MH. Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alphasubunits in heart via hierarchical phosphorylation of Ser485/491. J Biol Chem 2006; 281: 5335-5340.
-
(2006)
J Biol Chem
, vol.281
, pp. 5335-5340
-
-
Horman, S.1
Vertommen, D.2
Heath, R.3
Neumann, D.4
Mouton, V.5
Woods, A.6
Schlattner, U.7
Wallimann, T.8
Carling, D.9
Hue, L.10
Rider, M.H.11
-
22
-
-
84893064752
-
Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling
-
Zhang Y, Li R, Meng Y, Li S, Donelan W, Zhao Y, Qi L, Zhang M, Wang X, Cui T, Yang LJ and Tang D. Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling. Diabetes 2014; 63: 514-525.
-
(2014)
Diabetes
, vol.63
, pp. 514-525
-
-
Zhang, Y.1
Li, R.2
Meng, Y.3
Li, S.4
Donelan, W.5
Zhao, Y.6
Qi, L.7
Zhang, M.8
Wang, X.9
Cui, T.10
Yang, L.J.11
Tang, D.12
|