Irisin promotes human umbilical vein endothelial cell proliferation through the ERK signaling pathway and partly suppresses high glucose-induced apoptosis

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Song, Haibo ^a,b,d   Wu, Fei ^a,b   Zhang, Yuan ^a,b   Zhang, Yuzhu ^a,b   Wang, Fang ^a   Jiang, Miao ^a   Wang, Zhongde ^d   Zhang, Mingxiang ^b   Li, Shiwu ^a   Yang, Lijun ^a   Wang, Xing Li ^b   Cui, Taixing ^b,c   Tang, Dongqi ^a,b  

^a THE SECOND HOSPITAL OF SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d Zibo Maternal and Child Health Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CYTOKINE; GLUCOSE; IRISIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; UNCLASSIFIED DRUG; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; BAX PROTEIN, HUMAN; BCL2 PROTEIN, HUMAN; FIBRONECTIN; FNDC5 PROTEIN, HUMAN; NITRILE; PROTEIN KINASE INHIBITOR; RECOMBINANT PROTEIN;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EXTRACELLULAR SIGNAL RELATED KINASE SIGNALING PATHWAY; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BUTADIENES; CASPASE 3; CASPASE 9; CELL PROLIFERATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBRONECTINS; GENE EXPRESSION REGULATION; GLUCOSE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; NITRILES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 84908305311     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110273     Document Type: Article

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