-
1
-
-
84864568543
-
Proteasome inhibitors in multiple myeloma: 10 years later
-
Moreau, P., Richardson, P. G., Cavo, M., Orlowski, R. Z., San Miguel, J. F., Palumbo, A., and Harousseau, J. L. (2012) Proteasome inhibitors in multiple myeloma: 10 years later Blood 120, 947-959 10.1182/blood-2012-04-403733
-
(2012)
Blood
, vol.120
, pp. 947-959
-
-
Moreau, P.1
Richardson, P.G.2
Cavo, M.3
Orlowski, R.Z.4
San Miguel, J.F.5
Palumbo, A.6
Harousseau, J.L.7
-
2
-
-
84927176668
-
SCF ubiquitin ligase-targeted therapies
-
Skaar, J. R., Pagan, J. K., and Pagano, M. (2014) SCF ubiquitin ligase-targeted therapies Nat. Rev. Drug Discovery 13, 889-903 10.1038/nrd4432
-
(2014)
Nat. Rev. Drug Discovery
, vol.13
, pp. 889-903
-
-
Skaar, J.R.1
Pagan, J.K.2
Pagano, M.3
-
3
-
-
84938912227
-
An inhibitor of ubiquitin conjugation and aggresome formation
-
An, H. and Statsyuk, A. V. (2015) An inhibitor of ubiquitin conjugation and aggresome formation Chem. Sci. 6, 5235 10.1039/C5SC01351H
-
(2015)
Chem. Sci.
, vol.6
, pp. 5235
-
-
An, H.1
Statsyuk, A.V.2
-
4
-
-
4344559454
-
An unstructured initiation site is required for efficient proteasome-mediated degradation
-
Prakash, S., Tian, L., Ratliff, K. S., Lehotzky, R. E., and Matouschek, A. (2004) An unstructured initiation site is required for efficient proteasome-mediated degradation Nat. Struct. Mol. Biol. 11, 830-837 10.1038/nsmb814
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 830-837
-
-
Prakash, S.1
Tian, L.2
Ratliff, K.S.3
Lehotzky, R.E.4
Matouschek, A.5
-
5
-
-
84896032345
-
Paradigms of protein degradation by the proteasome
-
Inobe, T. and Matouschek, A. (2014) Paradigms of protein degradation by the proteasome Curr. Opin. Struct. Biol. 24, 156-164 10.1016/j.sbi.2014.02.002
-
(2014)
Curr. Opin. Struct. Biol.
, vol.24
, pp. 156-164
-
-
Inobe, T.1
Matouschek, A.2
-
6
-
-
0035266072
-
ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal
-
Lee, C., Schwartz, M. P., Prakash, S., Iwakura, M., and Matouschek, A. (2001) ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal Mol. Cell 7, 627-637 10.1016/S1097-2765(01)00209-X
-
(2001)
Mol. Cell
, vol.7
, pp. 627-637
-
-
Lee, C.1
Schwartz, M.P.2
Prakash, S.3
Iwakura, M.4
Matouschek, A.5
-
7
-
-
79951850741
-
Defining the geometry of the two-component proteasome degron
-
Inobe, T., Fishbain, S., Prakash, S., and Matouschek, A. (2011) Defining the geometry of the two-component proteasome degron Nat. Chem. Biol. 7, 161-167 10.1038/nchembio.521
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 161-167
-
-
Inobe, T.1
Fishbain, S.2
Prakash, S.3
Matouschek, A.4
-
8
-
-
84924125611
-
Sequence composition of disordered regions fine-tunes protein half-life
-
Fishbain, S., Inobe, T., Israeli, E., Chavali, S., Yu, H., Kago, G., Babu, M. M., and Matouschek, A. (2015) Sequence composition of disordered regions fine-tunes protein half-life Nat. Struct. Mol. Biol. 22, 214 10.1038/nsmb.2958
-
(2015)
Nat. Struct. Mol. Biol.
, vol.22
, pp. 214
-
-
Fishbain, S.1
Inobe, T.2
Israeli, E.3
Chavali, S.4
Yu, H.5
Kago, G.6
Babu, M.M.7
Matouschek, A.8
-
9
-
-
0032503999
-
Specific covalent labeling of recombinant protein molecules inside live cells
-
Griffin, B. A., Adams, S. R., and Tsien, R. Y. (1998) Specific covalent labeling of recombinant protein molecules inside live cells Science 281, 269-272 10.1126/science.281.5374.269
-
(1998)
Science
, vol.281
, pp. 269-272
-
-
Griffin, B.A.1
Adams, S.R.2
Tsien, R.Y.3
-
10
-
-
27144448780
-
Mammalian cell-based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity
-
Martin, B. R., Giepmans, B. N., Adams, S. R., and Tsien, R. Y. (2005) Mammalian cell-based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity Nat. Biotechnol. 23, 1308-1314 10.1038/nbt1136
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1308-1314
-
-
Martin, B.R.1
Giepmans, B.N.2
Adams, S.R.3
Tsien, R.Y.4
-
11
-
-
0037140742
-
New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: Synthesis and biological applications
-
Adams, S. R., Campbell, R. E., Gross, L. A., Martin, B. R., Walkup, G. K., Yao, Y., Llopis, J., and Tsien, R. Y. (2002) New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications J. Am. Chem. Soc. 124, 6063-6076 10.1021/ja017687n
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 6063-6076
-
-
Adams, S.R.1
Campbell, R.E.2
Gross, L.A.3
Martin, B.R.4
Walkup, G.K.5
Yao, Y.6
Llopis, J.7
Tsien, R.Y.8
-
12
-
-
0037144567
-
Concurrent translocation of multiple polypeptide chains through the proteasomal degradation channel
-
Lee, C., Prakash, S., and Matouschek, A. (2002) Concurrent translocation of multiple polypeptide chains through the proteasomal degradation channel J. Biol. Chem. 277, 34760-34765 10.1074/jbc.M204750200
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34760-34765
-
-
Lee, C.1
Prakash, S.2
Matouschek, A.3
-
13
-
-
47349126421
-
Mechanism of induced folding: Both folding before binding and binding before folding can be realized in staphylococcal nuclease mutants
-
Onitsuka, M., Kamikubo, H., Yamazaki, Y., and Kataoka, M. (2008) Mechanism of induced folding: Both folding before binding and binding before folding can be realized in staphylococcal nuclease mutants Proteins: Struct., Funct., Genet. 72, 837-847 10.1002/prot.21978
-
(2008)
Proteins: Struct., Funct., Genet.
, vol.72
, pp. 837-847
-
-
Onitsuka, M.1
Kamikubo, H.2
Yamazaki, Y.3
Kataoka, M.4
-
14
-
-
84866717363
-
Rapid production of antigen-specific monoclonal antibodies from a variety of animals
-
Kurosawa, N., Yoshioka, M., Fujimoto, R., Yamagishi, F., and Isobe, M. (2012) Rapid production of antigen-specific monoclonal antibodies from a variety of animals BMC Biol. 10, 80 10.1186/1741-7007-10-80
-
(2012)
BMC Biol.
, vol.10
, pp. 80
-
-
Kurosawa, N.1
Yoshioka, M.2
Fujimoto, R.3
Yamagishi, F.4
Isobe, M.5
-
15
-
-
0033674452
-
A ubiquitin-based tagging system for controlled modulation of protein stability
-
Stack, J. H., Whitney, M., Rodems, S. M., and Pollok, B. A. (2000) A ubiquitin-based tagging system for controlled modulation of protein stability Nat. Biotechnol. 18, 1298-1302 10.1038/82422
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 1298-1302
-
-
Stack, J.H.1
Whitney, M.2
Rodems, S.M.3
Pollok, B.A.4
-
16
-
-
59649115172
-
Proteasomes Can Degrade a Significant Proportion of Cellular Proteins Independent of Ubiquitination
-
Baugh, J. M., Viktorova, E. G., and Pilipenko, E. V. (2009) Proteasomes Can Degrade a Significant Proportion of Cellular Proteins Independent of Ubiquitination J. Mol. Biol. 386, 814-827 10.1016/j.jmb.2008.12.081
-
(2009)
J. Mol. Biol.
, vol.386
, pp. 814-827
-
-
Baugh, J.M.1
Viktorova, E.G.2
Pilipenko, E.V.3
-
17
-
-
0033453239
-
Attenuation of green fluorescent protein half-life in mammalian cells
-
Corish, P. and Tyler-Smith, C. (1999) Attenuation of green fluorescent protein half-life in mammalian cells Protein Eng., Des. Sel. 12, 1035-1040 10.1093/protein/12.12.1035
-
(1999)
Protein Eng., Des. Sel.
, vol.12
, pp. 1035-1040
-
-
Corish, P.1
Tyler-Smith, C.2
-
18
-
-
0345701307
-
Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate
-
Zhang, M., Pickart, C. M., and Coffino, P. (2003) Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate EMBO J. 22, 1488-1496 10.1093/emboj/cdg158
-
(2003)
EMBO J.
, vol.22
, pp. 1488-1496
-
-
Zhang, M.1
Pickart, C.M.2
Coffino, P.3
-
19
-
-
84880917833
-
The role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: Friend or foe?
-
Vervoort, S. J., van Boxtel, R., and Coffer, P. J. (2013) The role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: friend or foe? Oncogene 32, 3397-3409 10.1038/onc.2012.506
-
(2013)
Oncogene
, vol.32
, pp. 3397-3409
-
-
Vervoort, S.J.1
Van Boxtel, R.2
Coffer, P.J.3
-
20
-
-
84861526038
-
Syntenin-mediated regulation of Sox4 proteasomal degradation modulates transcriptional output
-
Beekman, J. M., Vervoort, S. J., Dekkers, F., van Vessem, M. E., Vendelbosch, S., Brugulat-Panès, A., van Loosdregt, J., Braat, A. K., and Coffer, P. J. (2012) Syntenin-mediated regulation of Sox4 proteasomal degradation modulates transcriptional output Oncogene 31, 2668 10.1038/onc.2011.445
-
(2012)
Oncogene
, vol.31
, pp. 2668
-
-
Beekman, J.M.1
Vervoort, S.J.2
Dekkers, F.3
Van Vessem, M.E.4
Vendelbosch, S.5
Brugulat-Panès, A.6
Van Loosdregt, J.7
Braat, A.K.8
Coffer, P.J.9
-
21
-
-
84863816082
-
A Mutually Inhibitory Feedback Loop between the 20S Proteasome and Its Regulator, NQO1
-
Moscovitz, O., Tsvetkov, P., Hazan, N., Michaelevski, I., Keisar, H., Ben-Nissan, G., Shaul, Y., and Sharon, M. (2012) A Mutually Inhibitory Feedback Loop between the 20S Proteasome and Its Regulator, NQO1 Mol. Cell 47, 76-86 10.1016/j.molcel.2012.05.049
-
(2012)
Mol. Cell
, vol.47
, pp. 76-86
-
-
Moscovitz, O.1
Tsvetkov, P.2
Hazan, N.3
Michaelevski, I.4
Keisar, H.5
Ben-Nissan, G.6
Shaul, Y.7
Sharon, M.8
-
22
-
-
84876524220
-
D(2)P(2): Database of disordered protein predictions
-
Oates, M. E., Romero, P., Ishida, T., Ghalwash, M., Mizianty, M. J., Xue, B., Dosztanyi, Z., Uversky, V. N., Obradovic, Z., Kurgan, L., Dunker, A. K., and Gough, J. (2013) D(2)P(2): database of disordered protein predictions Nucleic Acids Res. 41, D508-516 10.1093/nar/gks1226
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D508-516
-
-
Oates, M.E.1
Romero, P.2
Ishida, T.3
Ghalwash, M.4
Mizianty, M.J.5
Xue, B.6
Dosztanyi, Z.7
Uversky, V.N.8
Obradovic, Z.9
Kurgan, L.10
Dunker, A.K.11
Gough, J.12
-
23
-
-
84903975582
-
Disordered Proteinaceous Machines
-
Fuxreiter, M., Toth-Petroczy, A., Kraut, D. A., Matouschek, A. T., Lim, R. Y., Xue, B., Kurgan, L., and Uversky, V. N. (2014) Disordered Proteinaceous Machines Chem. Rev. 114, 6806 10.1021/cr4007329
-
(2014)
Chem. Rev.
, vol.114
, pp. 6806
-
-
Fuxreiter, M.1
Toth-Petroczy, A.2
Kraut, D.A.3
Matouschek, A.T.4
Lim, R.Y.5
Xue, B.6
Kurgan, L.7
Uversky, V.N.8
-
24
-
-
57149116929
-
Tight regulation of unstructured proteins: From transcript synthesis to protein degradation
-
Gsponer, J., Futschik, M. E., Teichmann, S. A., and Babu, M. M. (2008) Tight regulation of unstructured proteins: from transcript synthesis to protein degradation Science (Washington, DC, U. S.) 322, 1365-1368 10.1126/science.1163581
-
(2008)
Science (Washington, DC, U. S.)
, vol.322
, pp. 1365-1368
-
-
Gsponer, J.1
Futschik, M.E.2
Teichmann, S.A.3
Babu, M.M.4
-
25
-
-
84907406045
-
Intrinsically disordered segments affect protein half-life in the cell and during evolution
-
van der Lee, R., Lang, B., Kruse, K., Gsponer, J., Sanchez de Groot, N., Huynen, M. A., Matouschek, A., Fuxreiter, M., and Babu, M. M. (2014) Intrinsically disordered segments affect protein half-life in the cell and during evolution Cell Rep. 8, 1832-1844 10.1016/j.celrep.2014.07.055
-
(2014)
Cell Rep.
, vol.8
, pp. 1832-1844
-
-
Van Der Lee, R.1
Lang, B.2
Kruse, K.3
Gsponer, J.4
Sanchez De Groot, N.5
Huynen, M.A.6
Matouschek, A.7
Fuxreiter, M.8
Babu, M.M.9
-
26
-
-
84856373151
-
Proteasome inhibitors: An expanding army attacking a unique target
-
Kisselev, A. F., van der Linden, W. A., and Overkleeft, H. S. (2012) Proteasome inhibitors: an expanding army attacking a unique target Chem. Biol. 19, 99-115 10.1016/j.chembiol.2012.01.003
-
(2012)
Chem. Biol.
, vol.19
, pp. 99-115
-
-
Kisselev, A.F.1
Van Der Linden, W.A.2
Overkleeft, H.S.3
-
27
-
-
79952399087
-
Beyond natural antibodies: The power of in vitro display technologies
-
Bradbury, A. R., Sidhu, S., Dubel, S., and McCafferty, J. (2011) Beyond natural antibodies: the power of in vitro display technologies Nat. Biotechnol. 29, 245-254 10.1038/nbt.1791
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 245-254
-
-
Bradbury, A.R.1
Sidhu, S.2
Dubel, S.3
McCafferty, J.4
-
28
-
-
84907931054
-
Recent progress in generating intracellular functional antibody fragments to target and trace cellular components in living cells
-
Kaiser, P. D., Maier, J., Traenkle, B., Emele, F., and Rothbauer, U. (2014) Recent progress in generating intracellular functional antibody fragments to target and trace cellular components in living cells Biochim. Biophys. Acta, Proteins Proteomics 1844, 1933-1942 10.1016/j.bbapap.2014.04.019
-
(2014)
Biochim. Biophys. Acta, Proteins Proteomics
, vol.1844
, pp. 1933-1942
-
-
Kaiser, P.D.1
Maier, J.2
Traenkle, B.3
Emele, F.4
Rothbauer, U.5
-
29
-
-
0032509129
-
The fibronectin type III domain as a scaffold for novel binding proteins
-
Koide, A., Bailey, C. W., Huang, X., and Koide, S. (1998) The fibronectin type III domain as a scaffold for novel binding proteins J. Mol. Biol. 284, 1141-1151 10.1006/jmbi.1998.2238
-
(1998)
J. Mol. Biol.
, vol.284
, pp. 1141-1151
-
-
Koide, A.1
Bailey, C.W.2
Huang, X.3
Koide, S.4
-
30
-
-
0036240701
-
The proteasome: A novel target for cancer chemotherapy
-
Almond, J. B. and Cohen, G. M. (2002) The proteasome: a novel target for cancer chemotherapy Leukemia 16, 433-443 10.1038/sj.leu.2402417
-
(2002)
Leukemia
, vol.16
, pp. 433-443
-
-
Almond, J.B.1
Cohen, G.M.2
-
31
-
-
0033596124
-
Aberrant rel/nfkb genes and activity in human cancer
-
Rayet, B. and Gelinas, C. (1999) Aberrant rel/nfkb genes and activity in human cancer Oncogene 18, 6938-6947 10.1038/sj.onc.1203221
-
(1999)
Oncogene
, vol.18
, pp. 6938-6947
-
-
Rayet, B.1
Gelinas, C.2
|