-
1
-
-
65649115267
-
Recognition and processing of ubiquitin-protein conjugates by the proteasome
-
Finley D. Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu Rev Biochem 2009, 78:477-513.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 477-513
-
-
Finley, D.1
-
2
-
-
84878942836
-
Molecular architecture and assembly of the eukaryotic proteasome
-
Tomko R.J., Hochstrasser M. Molecular architecture and assembly of the eukaryotic proteasome. Annu Rev Biochem 2013, 82:415-445.
-
(2013)
Annu Rev Biochem
, vol.82
, pp. 415-445
-
-
Tomko, R.J.1
Hochstrasser, M.2
-
3
-
-
78650450552
-
Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution
-
Bohn S., Beck F., Sakata E., Walzthoeni T., Beck M., Aebersold R., Förster F., Baumeister W., Nickell S. Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Proc Natl Acad Sci U S A 2010, 107:20992-20997.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 20992-20997
-
-
Bohn, S.1
Beck, F.2
Sakata, E.3
Walzthoeni, T.4
Beck, M.5
Aebersold, R.6
Förster, F.7
Baumeister, W.8
Nickell, S.9
-
4
-
-
84863115607
-
Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy
-
Sakata E., Bohn S., Mihalache O., Kiss P., Beck F., Nagy I., Nickell S., Tanaka K., Saeki Y., Förster F., et al. Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy. Proc Natl Acad Sci U S A 2012, 109:1479-1484.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 1479-1484
-
-
Sakata, E.1
Bohn, S.2
Mihalache, O.3
Kiss, P.4
Beck, F.5
Nagy, I.6
Nickell, S.7
Tanaka, K.8
Saeki, Y.9
Förster, F.10
-
5
-
-
84856976866
-
Complete subunit architecture of the proteasome regulatory particle
-
Lander G.C., Estrin E., Matyskiela M.E., Bashore C., Nogales E., Martin A. Complete subunit architecture of the proteasome regulatory particle. Nature 2012, 482:186-191.
-
(2012)
Nature
, vol.482
, pp. 186-191
-
-
Lander, G.C.1
Estrin, E.2
Matyskiela, M.E.3
Bashore, C.4
Nogales, E.5
Martin, A.6
-
6
-
-
84857134729
-
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach
-
Lasker K., Förster F., Bohn S., Walzthoeni T., Villa E., Unverdorben P., Beck F., Aebersold R., Sali A., Baumeister W. Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc Natl Acad Sci U S A 2012, 109:1380-1387.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 1380-1387
-
-
Lasker, K.1
Förster, F.2
Bohn, S.3
Walzthoeni, T.4
Villa, E.5
Unverdorben, P.6
Beck, F.7
Aebersold, R.8
Sali, A.9
Baumeister, W.10
-
7
-
-
84866269021
-
Near-atomic resolution structural model of the yeast 26S proteasome
-
Beck F., Unverdorben P., Bohn S., Schweitzer A., Pfeifer G., Sakata E., Nickell S., Plitzko J.M., Villa E., Baumeister W., et al. Near-atomic resolution structural model of the yeast 26S proteasome. Proc Natl Acad Sci U S A 2012, 109:14870-14875.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 14870-14875
-
-
Beck, F.1
Unverdorben, P.2
Bohn, S.3
Schweitzer, A.4
Pfeifer, G.5
Sakata, E.6
Nickell, S.7
Plitzko, J.M.8
Villa, E.9
Baumeister, W.10
-
8
-
-
84859702750
-
Molecular model of the human 26S proteasome
-
da Fonseca P.C.A., He J., Morris E.P. Molecular model of the human 26S proteasome. Mol Cell 2012, 46:54-66.
-
(2012)
Mol Cell
, vol.46
, pp. 54-66
-
-
da Fonseca, P.C.A.1
He, J.2
Morris, E.P.3
-
9
-
-
84880157841
-
Conformational switching of the 26S proteasome enables substrate degradation
-
Matyskiela M.E., Lander G.C., Martin A. Conformational switching of the 26S proteasome enables substrate degradation. Nat Struct Mol Biol 2013, 20:781-788.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 781-788
-
-
Matyskiela, M.E.1
Lander, G.C.2
Martin, A.3
-
10
-
-
84876909425
-
Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation
-
Śledź P., Unverdorben P., Beck F., Pfeifer G., Schweitzer A., Förster F., Baumeister W. Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation. Proc Natl Acad Sci U S A 2013, 110:7264-7269.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 7264-7269
-
-
Śledź, P.1
Unverdorben, P.2
Beck, F.3
Pfeifer, G.4
Schweitzer, A.5
Förster, F.6
Baumeister, W.7
-
11
-
-
44349116590
-
Proteasome subunit Rpn13 is a novel ubiquitin receptor
-
Husnjak K., Elsasser S., Zhang N., Chen X., Randles L., Shi Y., Hofmann K., Walters K.J., Finley D., Dikic I. Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature 2008, 453:481-488.
-
(2008)
Nature
, vol.453
, pp. 481-488
-
-
Husnjak, K.1
Elsasser, S.2
Zhang, N.3
Chen, X.4
Randles, L.5
Shi, Y.6
Hofmann, K.7
Walters, K.J.8
Finley, D.9
Dikic, I.10
-
12
-
-
59649104242
-
Polyubiquitin substrates allosterically activate their own degradation by the 26S proteasome
-
Bech-Otschir D., Helfrich A., Enenkel C., Consiglieri G., Seeger M., Holzhütter H.-G., Dahlmann B., Kloetzel P.-M. Polyubiquitin substrates allosterically activate their own degradation by the 26S proteasome. Nat Struct Mol Biol 2009, 16:219-225.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 219-225
-
-
Bech-Otschir, D.1
Helfrich, A.2
Enenkel, C.3
Consiglieri, G.4
Seeger, M.5
Holzhütter, H.-G.6
Dahlmann, B.7
Kloetzel, P.-M.8
-
13
-
-
71149107057
-
Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening
-
Peth A., Besche H.C., Goldberg A.L. Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening. Mol Cell 2009, 36:794-804.
-
(2009)
Mol Cell
, vol.36
, pp. 794-804
-
-
Peth, A.1
Besche, H.C.2
Goldberg, A.L.3
-
14
-
-
69249241853
-
Variably modulated gating of the 26S proteasome by ATP and polyubiquitin
-
Li X., Demartino G.N. Variably modulated gating of the 26S proteasome by ATP and polyubiquitin. Biochem J 2009, 421:397-404.
-
(2009)
Biochem J
, vol.421
, pp. 397-404
-
-
Li, X.1
Demartino, G.N.2
-
15
-
-
84865094127
-
Identification of the Cdc48·20S proteasome as an ancient AAA+ proteolytic machine
-
Barthelme D., Sauer R.T. Identification of the Cdc48·20S proteasome as an ancient AAA+ proteolytic machine. Science 2012, 337:843-846.
-
(2012)
Science
, vol.337
, pp. 843-846
-
-
Barthelme, D.1
Sauer, R.T.2
-
16
-
-
84874452437
-
Bipartite determinants mediate an evolutionarily conserved interaction between Cdc48 and the 20S peptidase
-
Barthelme D., Sauer R.T. Bipartite determinants mediate an evolutionarily conserved interaction between Cdc48 and the 20S peptidase. Proc Natl Acad Sci U S A 2013, 110:3327-3332.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 3327-3332
-
-
Barthelme, D.1
Sauer, R.T.2
-
17
-
-
84870907436
-
Cleaning up: ER-associated degradation to the rescue
-
Brodsky J.L. Cleaning up: ER-associated degradation to the rescue. Cell 2012, 151:1163-1167.
-
(2012)
Cell
, vol.151
, pp. 1163-1167
-
-
Brodsky, J.L.1
-
18
-
-
79959389010
-
AAA+ proteases: ATP-fueled machines of protein destruction
-
Sauer R.T., Baker T.A. AAA+ proteases: ATP-fueled machines of protein destruction. Annu Rev Biochem 2011, 80:587-612.
-
(2011)
Annu Rev Biochem
, vol.80
, pp. 587-612
-
-
Sauer, R.T.1
Baker, T.A.2
-
21
-
-
50149086108
-
Diversity of degradation signals in the ubiquitin-proteasome system
-
Ravid T., Hochstrasser M. Diversity of degradation signals in the ubiquitin-proteasome system. Nat Rev Mol Cell Biol 2008, 9:679-690.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 679-690
-
-
Ravid, T.1
Hochstrasser, M.2
-
23
-
-
68049084674
-
Breaking the chains: structure and function of the deubiquitinases
-
Komander D., Clague M.J., Urbé S. Breaking the chains: structure and function of the deubiquitinases. Nat Rev Mol Cell Biol 2009, 10:550-563.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbé, S.3
-
24
-
-
82455179484
-
Systematic and quantitative assessment of the ubiquitin-modified proteome
-
Kim W., Bennett E.J., Huttlin E.L., Guo A., Li J., Possemato A., Sowa M.E., Rad R., Rush J., Comb M.J., et al. Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell 2011, 44:325-340.
-
(2011)
Mol Cell
, vol.44
, pp. 325-340
-
-
Kim, W.1
Bennett, E.J.2
Huttlin, E.L.3
Guo, A.4
Li, J.5
Possemato, A.6
Sowa, M.E.7
Rad, R.8
Rush, J.9
Comb, M.J.10
-
25
-
-
0034602845
-
Recognition of the polyubiquitin proteolytic signal
-
Thrower J.S., Hoffman L., Rechsteiner M., Pickart C.M. Recognition of the polyubiquitin proteolytic signal. EMBO J 2000, 19:94-102.
-
(2000)
EMBO J
, vol.19
, pp. 94-102
-
-
Thrower, J.S.1
Hoffman, L.2
Rechsteiner, M.3
Pickart, C.M.4
-
26
-
-
60549107173
-
Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome
-
Saeki Y., Kudo T., Sone T., Kikuchi Y., Yokosawa H., Toh-E A., Tanaka K. Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome. EMBO J 2009, 28:359-371.
-
(2009)
EMBO J
, vol.28
, pp. 359-371
-
-
Saeki, Y.1
Kudo, T.2
Sone, T.3
Kikuchi, Y.4
Yokosawa, H.5
Toh-E, A.6
Tanaka, K.7
-
27
-
-
63049125531
-
Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation
-
Xu P., Duong D.M., Seyfried N.T., Cheng D., Xie Y., Robert J., Rush J., Hochstrasser M., Finley D., Peng J. Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell 2009, 137:133-145.
-
(2009)
Cell
, vol.137
, pp. 133-145
-
-
Xu, P.1
Duong, D.M.2
Seyfried, N.T.3
Cheng, D.4
Xie, Y.5
Robert, J.6
Rush, J.7
Hochstrasser, M.8
Finley, D.9
Peng, J.10
-
28
-
-
34447523329
-
Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors
-
Boutet S.C., Disatnik M.-H., Chan L.S., Iori K., Rando T.A. Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors. Cell 2007, 130:349-362.
-
(2007)
Cell
, vol.130
, pp. 349-362
-
-
Boutet, S.C.1
Disatnik, M.-H.2
Chan, L.S.3
Iori, K.4
Rando, T.A.5
-
29
-
-
84867398821
-
The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation
-
Shabek N., Herman-Bachinsky Y., Buchsbaum S., Lewinson O., Haj-Yahya M., Hejjaoui M., Lashuel H.A., Sommer T., Brik A., Ciechanover A. The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation. Mol Cell 2012, 48:87-97.
-
(2012)
Mol Cell
, vol.48
, pp. 87-97
-
-
Shabek, N.1
Herman-Bachinsky, Y.2
Buchsbaum, S.3
Lewinson, O.4
Haj-Yahya, M.5
Hejjaoui, M.6
Lashuel, H.A.7
Sommer, T.8
Brik, A.9
Ciechanover, A.10
-
30
-
-
84862776836
-
APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1
-
Dimova N.V., Hathaway N.A., Lee B.-H., Kirkpatrick D.S., Berkowitz M.L., Gygi S.P., Finley D., King R.W. APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1. Nat Cell Biol 2012, 14:168-176.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 168-176
-
-
Dimova, N.V.1
Hathaway, N.A.2
Lee, B.-H.3
Kirkpatrick, D.S.4
Berkowitz, M.L.5
Gygi, S.P.6
Finley, D.7
King, R.W.8
-
31
-
-
84875231510
-
Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?
-
Nathan J.A., Kim H.T., Ting L., Gygi S.P., Goldberg A.L. Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?. EMBO J 2013, 32:552-565.
-
(2013)
EMBO J
, vol.32
, pp. 552-565
-
-
Nathan, J.A.1
Kim, H.T.2
Ting, L.3
Gygi, S.P.4
Goldberg, A.L.5
-
32
-
-
0035266072
-
ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal
-
Lee C., Schwartz M.P., Prakash S., Iwakura M., Matouschek A. ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal. Mol Cell 2001, 7:627-637.
-
(2001)
Mol Cell
, vol.7
, pp. 627-637
-
-
Lee, C.1
Schwartz, M.P.2
Prakash, S.3
Iwakura, M.4
Matouschek, A.5
-
33
-
-
4344559454
-
An unstructured initiation site is required for efficient proteasome-mediated degradation
-
Prakash S., Tian L., Ratliff K.S., Lehotzky R.E., Matouschek A. An unstructured initiation site is required for efficient proteasome-mediated degradation. Nat Struct Mol Biol 2004, 11:830-837.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 830-837
-
-
Prakash, S.1
Tian, L.2
Ratliff, K.S.3
Lehotzky, R.E.4
Matouschek, A.5
-
34
-
-
57749102552
-
Substrate selection by the proteasome during degradation of protein complexes
-
Prakash S., Inobe T., Hatch A.J., Matouschek A. Substrate selection by the proteasome during degradation of protein complexes. Nat Chem Biol 2009, 5:29-36.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 29-36
-
-
Prakash, S.1
Inobe, T.2
Hatch, A.J.3
Matouschek, A.4
-
35
-
-
30344466977
-
The processivity of multiubiquitination by the APC determines the order of substrate degradation
-
Rape M., Reddy S.K., Kirschner M.W. The processivity of multiubiquitination by the APC determines the order of substrate degradation. Cell 2006, 124:89-103.
-
(2006)
Cell
, vol.124
, pp. 89-103
-
-
Rape, M.1
Reddy, S.K.2
Kirschner, M.W.3
-
36
-
-
34247355517
-
Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation
-
Reddy S.K., Rape M., Margansky W.A., Kirschner M.W. Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation. Nature 2007, 446:921-925.
-
(2007)
Nature
, vol.446
, pp. 921-925
-
-
Reddy, S.K.1
Rape, M.2
Margansky, W.A.3
Kirschner, M.W.4
-
37
-
-
0031038169
-
Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome
-
Lam Y.A., Xu W., DeMartino G.N., Cohen R.E. Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome. Nature 1997, 385:737-740.
-
(1997)
Nature
, vol.385
, pp. 737-740
-
-
Lam, Y.A.1
Xu, W.2
DeMartino, G.N.3
Cohen, R.E.4
-
38
-
-
77956527159
-
Enhancement of proteasome activity by a small-molecule inhibitor of USP14
-
Lee B.-H., Lee M.J., Park S., Oh D.-C., Elsasser S., Chen P.-C., Gartner C., Dimova N., Hanna J., Gygi S.P., et al. Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature 2010, 467:179-184.
-
(2010)
Nature
, vol.467
, pp. 179-184
-
-
Lee, B.-H.1
Lee, M.J.2
Park, S.3
Oh, D.-C.4
Elsasser, S.5
Chen, P.-C.6
Gartner, C.7
Dimova, N.8
Hanna, J.9
Gygi, S.P.10
-
39
-
-
84856085129
-
Inhibition of proteasome deubiquitinating activity as a new cancer therapy
-
D'Arcy P., Brnjic S., Olofsson M.H., Fryknäs M., Lindsten K., De Cesare M., Perego P., Sadeghi B., Hassan M., Larsson R., et al. Inhibition of proteasome deubiquitinating activity as a new cancer therapy. Nat Med 2011, 17:1636-1640.
-
(2011)
Nat Med
, vol.17
, pp. 1636-1640
-
-
D'Arcy, P.1
Brnjic, S.2
Olofsson, M.H.3
Fryknäs, M.4
Lindsten, K.5
De Cesare, M.6
Perego, P.7
Sadeghi, B.8
Hassan, M.9
Larsson, R.10
-
40
-
-
84856373151
-
Proteasome inhibitors: an expanding army attacking a unique target
-
Kisselev A.F., van der Linden W.A., Overkleeft H.S. Proteasome inhibitors: an expanding army attacking a unique target. Chem Biol 2012, 19:99-115.
-
(2012)
Chem Biol
, vol.19
, pp. 99-115
-
-
Kisselev, A.F.1
van der Linden, W.A.2
Overkleeft, H.S.3
-
41
-
-
84861881296
-
The ubiquitin system, an immense realm
-
Varshavsky A. The ubiquitin system, an immense realm. Annu Rev Biochem 2012, 81:167-176.
-
(2012)
Annu Rev Biochem
, vol.81
, pp. 167-176
-
-
Varshavsky, A.1
-
42
-
-
33845600006
-
Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities
-
Crosas B., Hanna J., Kirkpatrick D.S., Zhang D.P., Tone Y., Hathaway N.A., Buecker C., Leggett D.S., Schmidt M., King R.W., et al. Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities. Cell 2006, 127:1401-1413.
-
(2006)
Cell
, vol.127
, pp. 1401-1413
-
-
Crosas, B.1
Hanna, J.2
Kirkpatrick, D.S.3
Zhang, D.P.4
Tone, Y.5
Hathaway, N.A.6
Buecker, C.7
Leggett, D.S.8
Schmidt, M.9
King, R.W.10
-
43
-
-
28544434064
-
A conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-kappaB
-
Tian L., Holmgren R.A., Matouschek A. A conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-kappaB. Nat Struct Mol Biol 2005, 12:1045-1053.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 1045-1053
-
-
Tian, L.1
Holmgren, R.A.2
Matouschek, A.3
-
44
-
-
75749101797
-
The ubiquitin ligase Hul5 promotes proteasomal processivity
-
Aviram S., Kornitzer D. The ubiquitin ligase Hul5 promotes proteasomal processivity. Mol Cell Biol 2010, 30:985-994.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 985-994
-
-
Aviram, S.1
Kornitzer, D.2
-
45
-
-
33846216003
-
Proteasome substrate degradation requires association plus extended peptide
-
Takeuchi J., Chen H., Coffino P. Proteasome substrate degradation requires association plus extended peptide. EMBO J 2007, 26:123-131.
-
(2007)
EMBO J
, vol.26
, pp. 123-131
-
-
Takeuchi, J.1
Chen, H.2
Coffino, P.3
-
46
-
-
84885428073
-
Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldase
-
Beckwith R., Estrin E., Worden E.J., Martin A. Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldase. Nat Struct Mol Biol 2013, 20:1164-1172.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 1164-1172
-
-
Beckwith, R.1
Estrin, E.2
Worden, E.J.3
Martin, A.4
-
47
-
-
79951850741
-
Defining the geometry of the two-component proteasome degron
-
Inobe T., Fishbain S., Prakash S., Matouschek A. Defining the geometry of the two-component proteasome degron. Nat Chem Biol 2011, 7:161-167.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 161-167
-
-
Inobe, T.1
Fishbain, S.2
Prakash, S.3
Matouschek, A.4
-
48
-
-
1542358787
-
Prediction and functional analysis of native disorder in proteins from the three kingdoms of life
-
Ward J.J., Sodhi J.S., McGuffin L.J., Buxton B.F., Jones D.T. Prediction and functional analysis of native disorder in proteins from the three kingdoms of life. J Mol Biol 2004, 337:635-645.
-
(2004)
J Mol Biol
, vol.337
, pp. 635-645
-
-
Ward, J.J.1
Sodhi, J.S.2
McGuffin, L.J.3
Buxton, B.F.4
Jones, D.T.5
-
49
-
-
79958072421
-
Intrinsically disordered proteins: regulation and disease
-
Babu M.M., van der Lee R., de Groot N.S., Gsponer J. Intrinsically disordered proteins: regulation and disease. Curr Opin Struct Biol 2011, 21:432-440.
-
(2011)
Curr Opin Struct Biol
, vol.21
, pp. 432-440
-
-
Babu, M.M.1
van der Lee, R.2
de Groot, N.S.3
Gsponer, J.4
-
50
-
-
57149116929
-
Tight regulation of unstructured proteins: from transcript synthesis to protein degradation
-
Gsponer J., Futschik M.E., Teichmann S.A., Babu M.M. Tight regulation of unstructured proteins: from transcript synthesis to protein degradation. Science 2008, 322:1365-1368.
-
(2008)
Science
, vol.322
, pp. 1365-1368
-
-
Gsponer, J.1
Futschik, M.E.2
Teichmann, S.A.3
Babu, M.M.4
-
51
-
-
41149125082
-
Structural disorder serves as a weak signal for intracellular protein degradation
-
Tompa P., Prilusky J., Silman I., Sussman J.L. Structural disorder serves as a weak signal for intracellular protein degradation. Proteins 2008, 71:903-909.
-
(2008)
Proteins
, vol.71
, pp. 903-909
-
-
Tompa, P.1
Prilusky, J.2
Silman, I.3
Sussman, J.L.4
-
52
-
-
55849136903
-
Global protein stability profiling in mammalian cells
-
Yen H.-C.S., Xu Q., Chou D.M., Zhao Z., Elledge S.J. Global protein stability profiling in mammalian cells. Science 2008, 322:918-923.
-
(2008)
Science
, vol.322
, pp. 918-923
-
-
Yen, H.-C.S.1
Xu, Q.2
Chou, D.M.3
Zhao, Z.4
Elledge, S.J.5
-
53
-
-
55849133733
-
Identification of SCF ubiquitin ligase substrates by global protein stability profiling
-
Yen H.-C.S., Elledge S.J. Identification of SCF ubiquitin ligase substrates by global protein stability profiling. Science 2008, 322:923-929.
-
(2008)
Science
, vol.322
, pp. 923-929
-
-
Yen, H.-C.S.1
Elledge, S.J.2
-
54
-
-
79960659875
-
Context-dependent resistance to proteolysis of intrinsically disordered proteins
-
Suskiewicz M.J., Sussman J.L., Silman I., Shaul Y. Context-dependent resistance to proteolysis of intrinsically disordered proteins. Protein Sci 2011, 20:1285-1297.
-
(2011)
Protein Sci
, vol.20
, pp. 1285-1297
-
-
Suskiewicz, M.J.1
Sussman, J.L.2
Silman, I.3
Shaul, Y.4
-
55
-
-
77449103113
-
Identification, analysis, and prediction of protein ubiquitination sites
-
Radivojac P., Vacic V., Haynes C., Cocklin R.R., Mohan A., Heyen J.W., Goebl M.G., Iakoucheva L.M. Identification, analysis, and prediction of protein ubiquitination sites. Proteins 2010, 78:365-380.
-
(2010)
Proteins
, vol.78
, pp. 365-380
-
-
Radivojac, P.1
Vacic, V.2
Haynes, C.3
Cocklin, R.R.4
Mohan, A.5
Heyen, J.W.6
Goebl, M.G.7
Iakoucheva, L.M.8
-
56
-
-
80052349174
-
Intrinsic disorder in ubiquitination substrates
-
Hagai T., Azia A., Tóth-Petróczy Á., Levy Y. Intrinsic disorder in ubiquitination substrates. J Mol Biol 2011, 412:319-324.
-
(2011)
J Mol Biol
, vol.412
, pp. 319-324
-
-
Hagai, T.1
Azia, A.2
Tóth-Petróczy, Á.3
Levy, Y.4
-
57
-
-
76649123968
-
Ubiquitin not only serves as a tag but also assists degradation by inducing protein unfolding
-
Hagai T., Levy Y. Ubiquitin not only serves as a tag but also assists degradation by inducing protein unfolding. Proc Natl Acad Sci U S A 2010, 107:2001-2006.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2001-2006
-
-
Hagai, T.1
Levy, Y.2
-
58
-
-
23144449583
-
Delivery of ubiquitinated substrates to protein-unfolding machines
-
Elsasser S., Finley D. Delivery of ubiquitinated substrates to protein-unfolding machines. Nat Cell Biol 2005, 7:742-749.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 742-749
-
-
Elsasser, S.1
Finley, D.2
-
59
-
-
17044368771
-
The UBA2 domain functions as an intrinsic stabilization signal that protects Rad23 from proteasomal degradation
-
Heessen S., Masucci M., Dantuma N. The UBA2 domain functions as an intrinsic stabilization signal that protects Rad23 from proteasomal degradation. Mol Cell 2005, 18:225-235.
-
(2005)
Mol Cell
, vol.18
, pp. 225-235
-
-
Heessen, S.1
Masucci, M.2
Dantuma, N.3
-
60
-
-
84878270699
-
Rad23 escapes degradation because it lacks a proteasome initiation region
-
Fishbain S., Prakash S., Herrig A., Elsasser S., Matouschek A. Rad23 escapes degradation because it lacks a proteasome initiation region. Nat Commun 2011, 2:192.
-
(2011)
Nat Commun
, vol.2
, pp. 192
-
-
Fishbain, S.1
Prakash, S.2
Herrig, A.3
Elsasser, S.4
Matouschek, A.5
-
61
-
-
84867582157
-
C-terminal UBA domains protect ubiquitin receptors by preventing initiation of protein degradation
-
Heinen C., Acs K., Hoogstraten D., Dantuma N.P. C-terminal UBA domains protect ubiquitin receptors by preventing initiation of protein degradation. Nat Commun 2011, 2:191.
-
(2011)
Nat Commun
, vol.2
, pp. 191
-
-
Heinen, C.1
Acs, K.2
Hoogstraten, D.3
Dantuma, N.P.4
-
62
-
-
0025345753
-
Cis-trans recognition and subunit-specific degradation of short-lived proteins
-
Johnson E., Gonda D., Varshavsky A. cis-trans recognition and subunit-specific degradation of short-lived proteins. Nature 1990, 346:287-291.
-
(1990)
Nature
, vol.346
, pp. 287-291
-
-
Johnson, E.1
Gonda, D.2
Varshavsky, A.3
-
63
-
-
0025331090
-
In vivo degradation of a transcriptional regulator: the yeast alpha 2 repressor
-
Hochstrasser M., Varshavsky A. In vivo degradation of a transcriptional regulator: the yeast alpha 2 repressor. Cell 1990, 61:697-708.
-
(1990)
Cell
, vol.61
, pp. 697-708
-
-
Hochstrasser, M.1
Varshavsky, A.2
-
64
-
-
0034845197
-
Selective degradation of ubiquitinated Sic1 by purified 26S proteasome yields active S phase cyclin-Cdk
-
Verma R., McDonald H., Yates J.R., Deshaies R.J. Selective degradation of ubiquitinated Sic1 by purified 26S proteasome yields active S phase cyclin-Cdk. Mol Cell 2001, 8:439-448.
-
(2001)
Mol Cell
, vol.8
, pp. 439-448
-
-
Verma, R.1
McDonald, H.2
Yates, J.R.3
Deshaies, R.J.4
-
65
-
-
0344578064
-
APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5
-
Nasmyth K., Shirayama M., Tóth A., Gálová M. APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5. Nature 1999, 402:203-207.
-
(1999)
Nature
, vol.402
, pp. 203-207
-
-
Nasmyth, K.1
Shirayama, M.2
Tóth, A.3
Gálová, M.4
-
66
-
-
59649115172
-
Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination
-
Baugh J.M., Viktorova E.G., Pilipenko E.V. Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination. J Mol Biol 2009, 386:814-827.
-
(2009)
J Mol Biol
, vol.386
, pp. 814-827
-
-
Baugh, J.M.1
Viktorova, E.G.2
Pilipenko, E.V.3
-
67
-
-
0026714435
-
Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination
-
Murakami Y., Matsufuji S., Kameji T., Hayashi S., Igarashi K., Tamura T., Tanaka K., Ichihara A. Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination. Nature 1992, 360:597-599.
-
(1992)
Nature
, vol.360
, pp. 597-599
-
-
Murakami, Y.1
Matsufuji, S.2
Kameji, T.3
Hayashi, S.4
Igarashi, K.5
Tamura, T.6
Tanaka, K.7
Ichihara, A.8
-
68
-
-
0345701307
-
Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate
-
Zhang M., Pickart C.M., Coffino P. Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate. EMBO J 2003, 22:1488-1496.
-
(2003)
EMBO J
, vol.22
, pp. 1488-1496
-
-
Zhang, M.1
Pickart, C.M.2
Coffino, P.3
-
69
-
-
0034327510
-
Catalytic activities of the 20 S proteasome, a multicatalytic proteinase complex
-
Orlowski M., Wilk S. Catalytic activities of the 20 S proteasome, a multicatalytic proteinase complex. Arch Biochem Biophys 2000, 383:1-16.
-
(2000)
Arch Biochem Biophys
, vol.383
, pp. 1-16
-
-
Orlowski, M.1
Wilk, S.2
-
70
-
-
34250342888
-
Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome
-
Chen X., Barton L.F., Chi Y., Clurman B.E., Roberts J.M. Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome. Mol Cell 2007, 26:843-852.
-
(2007)
Mol Cell
, vol.26
, pp. 843-852
-
-
Chen, X.1
Barton, L.F.2
Chi, Y.3
Clurman, B.E.4
Roberts, J.M.5
-
71
-
-
84890174353
-
Ubiquitin-independent proteasomal degradation
-
Erales J., Coffino P. Ubiquitin-independent proteasomal degradation. Biochim Biophys Acta 2014, 1843:216-221.
-
(2014)
Biochim Biophys Acta
, vol.1843
, pp. 216-221
-
-
Erales, J.1
Coffino, P.2
-
72
-
-
14644446056
-
20S proteasomal degradation of ornithine decarboxylase is regulated by NQO1
-
Asher G., Bercovich Z., Tsvetkov P., Shaul Y., Kahana C. 20S proteasomal degradation of ornithine decarboxylase is regulated by NQO1. Mol Cell 2005, 17:645-655.
-
(2005)
Mol Cell
, vol.17
, pp. 645-655
-
-
Asher, G.1
Bercovich, Z.2
Tsvetkov, P.3
Shaul, Y.4
Kahana, C.5
-
73
-
-
84863816082
-
A mutually inhibitory feedback loop between the 20S proteasome and its regulator, NQO1
-
Moscovitz O., Tsvetkov P., Hazan N., Michaelevski I., Keisar H., Ben-Nissan G., Shaul Y., Sharon M. A mutually inhibitory feedback loop between the 20S proteasome and its regulator, NQO1. Mol Cell 2012, 47:76-86.
-
(2012)
Mol Cell
, vol.47
, pp. 76-86
-
-
Moscovitz, O.1
Tsvetkov, P.2
Hazan, N.3
Michaelevski, I.4
Keisar, H.5
Ben-Nissan, G.6
Shaul, Y.7
Sharon, M.8
-
74
-
-
84875252687
-
Advances in characterizing ubiquitylation sites by mass spectrometry
-
Sylvestersen K.B., Young C., Nielsen M.L. Advances in characterizing ubiquitylation sites by mass spectrometry. Curr Opin Chem Biol 2013, 17:49-58.
-
(2013)
Curr Opin Chem Biol
, vol.17
, pp. 49-58
-
-
Sylvestersen, K.B.1
Young, C.2
Nielsen, M.L.3
-
75
-
-
78651225388
-
Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling
-
Xu G., Paige J.S., Jaffrey S.R. Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. Nat Biotechnol 2010, 28:868-873.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 868-873
-
-
Xu, G.1
Paige, J.S.2
Jaffrey, S.R.3
-
76
-
-
84867103151
-
Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues
-
Wagner S.A., Beli P., Weinert B.T., Schölz C., Kelstrup C.D., Young C., Nielsen M.L., Olsen J.V., Brakebusch C., Choudhary C. Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Mol Cell Proteomics 2012, 11:1578-1585.
-
(2012)
Mol Cell Proteomics
, vol.11
, pp. 1578-1585
-
-
Wagner, S.A.1
Beli, P.2
Weinert, B.T.3
Schölz, C.4
Kelstrup, C.D.5
Young, C.6
Nielsen, M.L.7
Olsen, J.V.8
Brakebusch, C.9
Choudhary, C.10
-
77
-
-
84883229070
-
A cotranslational ubiquitination pathway for quality control of misfolded proteins
-
Wang F., Durfee L.A., Huibregtse J.M. A cotranslational ubiquitination pathway for quality control of misfolded proteins. Mol Cell 2013, 50:368-378.
-
(2013)
Mol Cell
, vol.50
, pp. 368-378
-
-
Wang, F.1
Durfee, L.A.2
Huibregtse, J.M.3
-
78
-
-
84883210213
-
Principles of cotranslational ubiquitination and quality control at the ribosome
-
Duttler S., Pechmann S., Frydman J. Principles of cotranslational ubiquitination and quality control at the ribosome. Mol Cell 2013, 50:379-393.
-
(2013)
Mol Cell
, vol.50
, pp. 379-393
-
-
Duttler, S.1
Pechmann, S.2
Frydman, J.3
-
79
-
-
33748377124
-
Quantification of protein half-lives in the budding yeast proteome
-
Belle A., Tanay A., Bitincka L., Shamir R., O'Shea E.K. Quantification of protein half-lives in the budding yeast proteome. Proc Natl Acad Sci U S A 2006, 103:13004-13009.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 13004-13009
-
-
Belle, A.1
Tanay, A.2
Bitincka, L.3
Shamir, R.4
O'Shea, E.K.5
-
80
-
-
79956322553
-
Global quantification of mammalian gene expression control
-
Schwanhäusser B., Busse D., Li N., Dittmar G., Schuchhardt J., Wolf J., Chen W., Selbach M. Global quantification of mammalian gene expression control. Nature 2011, 473:337-342.
-
(2011)
Nature
, vol.473
, pp. 337-342
-
-
Schwanhäusser, B.1
Busse, D.2
Li, N.3
Dittmar, G.4
Schuchhardt, J.5
Wolf, J.6
Chen, W.7
Selbach, M.8
-
81
-
-
79951472959
-
Proteome half-life dynamics in living human cells
-
Eden E., Geva-Zatorsky N., Issaeva I., Cohen A., Dekel E., Danon T., Cohen L., Mayo A., Alon U. Proteome half-life dynamics in living human cells. Science 2011, 331:764-768.
-
(2011)
Science
, vol.331
, pp. 764-768
-
-
Eden, E.1
Geva-Zatorsky, N.2
Issaeva, I.3
Cohen, A.4
Dekel, E.5
Danon, T.6
Cohen, L.7
Mayo, A.8
Alon, U.9
-
82
-
-
80054694510
-
Global identification of modular cullin-RING ligase substrates
-
Emanuele M.J., Elia A.E.H., Xu Q., Thoma C.R., Izhar L., Leng Y., Guo A., Chen Y.-N., Rush J., Hsu P.W.-C., et al. Global identification of modular cullin-RING ligase substrates. Cell 2011, 147:459-474.
-
(2011)
Cell
, vol.147
, pp. 459-474
-
-
Emanuele, M.J.1
Elia, A.E.H.2
Xu, Q.3
Thoma, C.R.4
Izhar, L.5
Leng, Y.6
Guo, A.7
Chen, Y.-N.8
Rush, J.9
Hsu, P.W.-C.10
|