Tomato (Lycopersicon esculentum) supplementation induces changes in cardiac miRNA expression, reduces oxidative stress and left ventricular mass, and improves diastolic function

Nutrients

Volumn 7, Issue 11, 2015, Pages 9640-9649

  Pereira, Bruna L B ^a   Arruda, Fernanda C O ^a   Reis, Patrícia P ^a   Felix, Tainara F ^a   Santos, Priscila P ^a   Rafacho, Bruna P ^a   Gonçalves, Andrea F ^a   Claro, Renan T ^a   Azevedo, Paula S ^a   Polegato, Bertha F ^a   Okoshi, Katashi ^a   Fernandes, Ana A H ^a   Paiva, Sergio A R ^a   Zornoff, Leonardo A M ^a   Minicucci, Marcos F ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Hypertrophy; MicroRNA; Oxidative stress; Tomato

Indexed keywords

CATALASE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CORN OIL; GLUTATHIONE PEROXIDASE; LIPID HYDROPEROXIDE; MICRORNA; MICRORNA 107; MICRORNA 350; MICRORNA 486; MICRORNA 872; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; MIRN107 MICRORNA, RAT; MIRN350 MICRORNA, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY DIAMETER; ARTICLE; BLOOD FLOW VELOCITY; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; DIET SUPPLEMENTATION; DIETARY INTAKE; DOWN REGULATION; ELECTROCARDIOGRAPHY; GENE EXPRESSION REGULATION; HEART FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART MUSCLE CELL; HEART RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MORPHOMETRICS; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; TOMATO; TRANSTHORACIC ECHOCARDIOGRAPHY; UPREGULATION; ANATOMY AND HISTOLOGY; ANIMAL; CHEMISTRY; DIASTOLE; DIET; GENETICS; HEART; HEART VENTRICLE; METABOLISM; PHYSIOLOGY; WISTAR RAT;

ANIMALS; DIASTOLE; DIET; DOWN-REGULATION; HEART; HEART VENTRICLES; LYCOPERSICON ESCULENTUM; MALE; MICRORNAS; OXIDATIVE STRESS; RATS; RATS, WISTAR; UP-REGULATION;

EID: 84947727132     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu7115493     Document Type: Article

References (40)

1. World Health Organization. Cardiovascular Diseases. Available online: http://www.who.int/mediacentre/factsheets/fs317/en/ (accessed on 14 June 2015).
2. Burton-Freeman, B.M.; Sesso, H.D. Whole food versus supplement: Comparing the clinical evidence of tomato intake and lycopene supplementation on cardiovascular risk factors. Adv. Nutr.2014, 5, 457–485.
3. Arab, L.; Steck, S. Lycopene and cardiovascular disease. Am. J. Clin. Nutr. 2000, 71, 1691S–1695S.
4. Riso, P.; Visioli, F.; Grande, S.; Guarnieri, S.; Gardana, C.; Simonetti, P.; Porrini, M. Effects of a tomato-based drink on markers of inflammation, immunomodulation, and oxidative stress. J. Agric. Food Chem. 2006, 54, 2563–2566.
5. Raiola, A.; Rigano, M.M.; Calafiore, R.; Frusciante, L.; Barone, A. Enhancing the health-promoting effects of tomato fruit for biofortified food. Mediat. Inflamm. 2014, 2014.
6. Hsu, Y.M.; Lai, C.H.; Chang, C.Y.; Fan, C.T.; Chen, C.T.; Wu, C.H. Characterizing the lipid-lowering effects and antioxidant mechanism of tomato paste. Biosci. Biotechnol. Biochem. 2008,72, 677–685.
7. Böhm, V. Lycopene and heart health. Mol. Nutr. Food Res. 2012, 56, 296–303.
8. Ben-Dor, A.; Steiner, M.; Gheber, L.; Danilenko, M.; Dubi, N.; Linnewiel, K.; Zick, A.; Sharoni, Y.; Levy, J. Carotenoids activate the antioxidant response element transcription system. Mol. Cancer Ther. 2005, 4, 177–186.
9. Ghavipour, M.; Saedisomeolia, A.; Djalali, M.; Sotoudeh, G.; Eshraghyan, M.R.; Moghadam, A.M.; Wood, L.G. Tomato juice consumption reduces systemic inflammation in overweight and obese females. Br. J. Nutr. 2013, 109, 2031–2035.
10. McEneny, J.; Wade, L.; Young, I.S.; Masson, L.; Duthie, G.; McGinty, A.; McMaster, C.; Thies, F. Lycopene intervention reduces inflammation and improves HDL functionality in moderately overweight middle-aged individuals. J. Nutr. Biochem. 2013, 24, 163–168.
11. Xaplanteris, P.; Pietri, P.; Terentes-Printzios, D.; Kardara, D.; Alexopoulos, N.; Aznaouridis, K.; Miliou, A.; Stefanadis, C. Tomato paste supplementation improves endotelial dynamics and reduces plasma total oxidative status in healthy subjects. Nutr. Res. 2012, 32, 390–394.
12. Ferreira, A.L.; Salvadori, D.M.; Nascimento, M.C.; Rocha, N.S.; Correa, C.R.; Pereira, E.J.; Matsubara, L.S.; Matsubara, B.B.; Ladeira, M.S. Tomato-oleoresin supplement prevents doxorubicin-induced cardiac myocyte oxidative DNA damage in rats. Mutat. Res. 2007, 631, 26–35.
13. Mohamadin, A.M.; Elberry, A.A.; Mariee, A.D.; Morsy, G.M.; al-Abbasi, F.A. Lycopene attenuates oxidative stress and heart lysosomal damage in isoproterenol induced cardiotoxicity in rats: A biochemical study. Pathophysiology 2012, 19, 121–130.
14. Upaganlawar, A.; Patel, V.; Balaraman, R. Tomato lycopene attenuates myocardil infarction induced by isoproterenol: Electrocardiographic, biochemical and anti-apoptotic study. Asian Pac. J. Trop. Biomed. 2012, 2, 345–351.
15. Luvizotto, R.; Nascimento, A.; Miranda, N.; Wang, X.D.; Ferreira, A. Lycopene-rich tomato oleoresin modulates plasma adiponectin concentration and mRNA levels of adiponectin, SIRT1, and FoxO1 in adipose tissue of obese rats. Hum. Exp. Toxicol. 2015, 34, 612–619.
16. Romaine, S.P.; Tomaszewski, M.; Condorelli, G.; Samani, N.J. MicroRNAs in cardiovascular disease: An introduction for clinicians. Heart 2015, 101, 921–928.
17. Bansal, P.; Kumar, S.; Shreesh, G.; Ojha, K.; Nandave, M.; Mittal, R.; Kumari, S.; Arya, D.S. Cardioprotective effect of lycopene in the experimental model of myocardial ischemia-reperfusion injury. Mol. Cell. Biochem. 2006, 289, 1–9.
18. Breinholt, V.; Sùren, T. Dose-response effects of lycopene on selected drug-metabolizing and antioxidant enzymes in the rat. Cancer Lett. 2000, 154, 201–210.
19. Riso, P.; Porrini, M. Determination of carotenoids in vegetable foods and plasma. Int. J. Vitam. Nutr. Res. 1997, 67, 47–54.
20. Yeum, K.J.; Booth, S.L.; Sadowski, J.A.; Liu, C.; Tang, G.; Krinsky, N.I.; Russell, R.M. Human plasma carotenoid response to the ingestion of controlled diets high in fruits and vegetables. Am. J. Clin. Nutr. 1996, 64, 594–602.
21. Reagan-Shaw, S.; Nihal, M.; Ahmad, N. Dose translation from animal to human studies revisited. FASEB J. 2007, 22, 659–661.
22. Lang, R.M.; Bierig, M.; Devereux, R.B.; Flachskampf, F.A.; Foster, E.; Pellikka, P.A.; Picard, M.H.; Roman, M.J.; Seward, J.; Shanewise, J.S.; et al. Recommendations for chamber quantification: A report from the American Society of Echocardiography’s guidelines and standards committee and the chamber quantification writing group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology.J. Am. Soc. Echocardiogr. 2005, 18, 1440–1463.
23. Minicucci, M.F.; Azevedo, P.S.; Oliveira, S.A., Jr.; Martinez, P.F.; Chiuso-Minicucci, F.; Polegato, B.F.; Justulin, L.A.; Matsubara, L.S.; Matsubara, B.B.; Paiva, S.A.; et al. Tissue vitamin A insufficiency results in adverse ventricular remodeling after experimental myocardial infarction.Cell Physiol. Biochem. 2010, 26, 523–530.
24. Burneiko, R.C.M.; Diniz, Y.S.; Galhardi, C.M.; Rodrigues, H.G.; Ebaid, G.M.X.; Faine, L.A.; Padovani, C.R.; Cicogna, A.C.; Novelli, E.L. Interaction of hypercaloric diet and physical exercise on lipid profile, oxidative stress and antioxidant defenses. Food Chem. Toxicol. 2006, 44, 1167–1172.
25. Nakamura, W.; Hosoda, S.; Hayashi, K. Purification and properties of rat liver glutathione peroxidase. Biochem. Biophys. Acta 1974, 358, 251–261.
26. Ewing, J.F.; Janero, D.R. Microplate superoxide dismutase assay employing a nonenzimatic superoxide generator. Anal. Biochem. 1995, 232, 243–248.
27. Assalin, H.B.; Rafacho, B.P.; dos Santos, P.P.; Ardisson, L.P.; Roscani, M.G.; Chiuso-Minicucci, F.; Barbisan, L.F.; Fernandes, A.A.; Azevedo, P.S.; Minicucci, M.F.; et al. Impact of the length of vitamin D deficiency on cardiac remodeling. Circ. Heart Fail. 2013, 6, 809–816.
28. Cervigne, N.K.; Reis, P.P.; Machado, J.; Sadikovic, B.; Bradley, G.; Galloni, N.N.; Pintilie, M.; Jurisica, I.; Perez-Ordonez, B.; Gilbert, R.; et al. Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma. Hum. Mol. Genet. 2009, 18, 4818–4829.
29. Bustin, S.A.; Benes, V.; Garson, J.A.; Hellemans, J.; Huggett, J.; Kubista, M.; Mueller, R.; Nolan, T.; Pfaffl, M.W.; Shipley, G.L.; et al. The MIQE guidelines: Minimum information for publication of quantitative real-time PCR experiments. Clin. Chem. 2009, 55, 611–622.
30. Eisen, M.B.; Spellman, P.T.; Brown, P.O.; Botstein, D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA 1998, 95, 14863–14868.
31. Turakhia, M.P.; Schiller, N.B.; Whooley, M.A. Prognostic significance of increased left ventricular mass index to mortality and sudden death in patients with stable coronary heart disease (from the Heart and Soul Study). Am. J. Cardiol. 2008, 102, 1131–1135.
32. Bouzas-Mosquera, A.; Broullón, F.J.; Álvarez-García, N.; Peteiro, J.; Mosquera, V.X.; Castro-Beiras, A. Association of left ventricular mass with all-cause mortality, myocardial infarction and stroke. PLoS ONE 2012, 7, e45570.
33. Droge, W. Free radicals in the physiological control of cell function. Physiol. Rev. 2002, 82, 47–95.
34. Rafacho, B.P.; Azevedo, P.S.; Polegato, B.F.; Fernandes, A.A.; Bertoline, M.A.; Fernandes, D.C.; Chiuso-Minicucci, F.; Roscani, M.G.; dos Santos, P.P.; Matsubara, L.S.; et al. Tobacco smoke induces ventricular remodeling associated with an increase in NADPH oxidase activity. Cell Physiol. Biochem. 2011, 27, 305–312.
35. Ahn, J.; Lee, H.; Jung, C.H.; Ha, T. Lycopene inhibits hepatic steatosis via microRNA-21-induced downregulation of fatty acid-binding protein 7 in mice fed a high-fat diet. Mol. Nutr. Food Res.2012, 56, 1665–1674.
36. Topkara, V.K.; Mann, D.L. Role of microRNAs in cardiac remodeling and heart failure.Cardiovac. Drugs Ther. 2011, 25, 171–182.
37. Ge, Y.; Pan, S.; Guan, D.; Yin, H.; Fan, Y.; Liu, J.; Zhang, S.; Zhang, H.; Feng, L.; Wang, Y.; et al. MicroRNA-350 induces pathological heart hypertrophy by repressing both p38 and JNK pathways. Biochim. Biophys. Acta 2013, 1832, 1–10.
38. Hitachi, K.; Nakatani, M.; Tsuchida, K. Myostatin signaling regulates Akt activity via the regulation of miR-486 expression. Int. J. Biochem. Cell Biol. 2014, 47, 93–103.
39. Hulsmans, M.; de Keyzer, D.; Holvoet, P. MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis. FASEB J. 2011, 25, 2515–2527.
40. Meng, S.; Cao, J.T.; Wang, L.S.; Zhou, Q.; Li, Y.; Shen, C.; Zhang, X.; Wang, C. MicroRNA 107 partly inhibits endothelial progenitor cells differentiation via HIF-1β. PLoS ONE 2012, 7, e40323.