-
1
-
-
84905029258
-
Comprehensive molecular profiling of lung adenocarcinoma
-
Cancer Genome Atlas Research Network: Comprehensive molecular profiling of lung adenocarcinoma. Nature 511:543-550, 2014
-
(2014)
Nature
, vol.511
, pp. 543-550
-
-
Cancer Genome Atlas Research Network1
-
2
-
-
48549098388
-
Identification of novel isoforms of the EML4-ALK transforming gene in non-small-cell lung cancer
-
Choi YL, Takeuchi K, Soda M, et al: Identification of novel isoforms of the EML4-ALK transforming gene in non-small-cell lung cancer. Cancer Res 68:4971-4976, 2008
-
(2008)
Cancer Res
, vol.68
, pp. 4971-4976
-
-
Choi, Y.L.1
Takeuchi, K.2
Soda, M.3
-
3
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
Soda M, Choi YL, Enomoto M, et al: Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 448:561-566, 2007
-
(2007)
Nature
, vol.448
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
-
4
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, et al: Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 363:1693-1703, 2010
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
-
5
-
-
57349100409
-
Non-solid oncogenes in solid tumors: EML4-ALK fusion genes in lung cancer
-
Mano H: Non-solid oncogenes in solid tumors: EML4-ALK fusion genes in lung cancer. Cancer Sci 99:2349-2355, 2008
-
(2008)
Cancer Sci
, vol.99
, pp. 2349-2355
-
-
Mano, H.1
-
6
-
-
84881256393
-
ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: An analysis of 1, 683 patients with non-small-cell lung cancer
-
Gainor JF, Varghese AM, Ou SH, et al: ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: An analysis of 1, 683 patients with non-small-cell lung cancer. Clin Cancer Res 19:4273-4281, 2013
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4273-4281
-
-
Gainor, J.F.1
Varghese, A.M.2
Ou, S.H.3
-
7
-
-
84879071011
-
Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
-
Shaw AT, Kim DW, Nakagawa K, et al: Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N Engl J Med 368:2385-2394, 2013
-
(2013)
N Engl J Med
, vol.368
, pp. 2385-2394
-
-
Shaw, A.T.1
Kim, D.W.2
Nakagawa, K.3
-
8
-
-
84856990335
-
Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small-cell lung cancer
-
Doebele RC, Pilling AB, Aisner DL, et al: Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small-cell lung cancer. Clin Cancer Res 18:1472-1482, 2012
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1472-1482
-
-
Doebele, R.C.1
Pilling, A.B.2
Aisner, D.L.3
-
9
-
-
84856999699
-
Mechanisms of acquired crizotinib resistance in ALK-rearranged lung cancers
-
Katayama R, Shaw AT, Khan TM, et al: Mechanisms of acquired crizotinib resistance in ALK-rearranged lung cancers. Sci Transl Med 4:120ra17, 2012
-
(2012)
Sci Transl Med
, vol.4
, pp. 120ra17
-
-
Katayama, R.1
Shaw, A.T.2
Khan, T.M.3
-
10
-
-
84903466222
-
The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small-cell lung cancer
-
Friboulet L, Li N, Katayama R, et al: The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small-cell lung cancer. Cancer Discov 4:662-673, 2014
-
(2014)
Cancer Discov
, vol.4
, pp. 662-673
-
-
Friboulet, L.1
Li, N.2
Katayama, R.3
-
11
-
-
84896957081
-
Ceritinib in ALK-rearranged non-smallcell lung cancer
-
Shaw AT, Kim DW, Mehra R, et al: Ceritinib in ALK-rearranged non-smallcell lung cancer. N Engl J Med 370:1189-1197, 2014
-
(2014)
N Engl J Med
, vol.370
, pp. 1189-1197
-
-
Shaw, A.T.1
Kim, D.W.2
Mehra, R.3
-
12
-
-
84964240053
-
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution
-
McGranahan N, Swanton C: Biological and therapeutic impact of intratumor heterogeneity in cancer evolution. Cancer Cell 27:15-26, 2015
-
(2015)
Cancer Cell
, vol.27
, pp. 15-26
-
-
McGranahan, N.1
Swanton, C.2
-
13
-
-
84907855592
-
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
-
de Bruin EC, McGranahan N, Mitter R, et al: Spatial and temporal diversity in genomic instability processes defines lung cancer evolution. Science 346:251-256, 2014
-
(2014)
Science
, vol.346
, pp. 251-256
-
-
De Bruin, E.C.1
McGranahan, N.2
Mitter, R.3
-
14
-
-
84907808265
-
Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing
-
Zhang J, Fujimoto J, Zhang J, et al: Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing. Science 346:256-259, 2014
-
(2014)
Science
, vol.346
, pp. 256-259
-
-
Zhang, J.1
Fujimoto, J.2
Zhang, J.3
-
15
-
-
84938770152
-
Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy
-
epub ahead of print on May 23
-
Murugaesu N, Wilson GA, Birkbak NJ, et al: Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy. Cancer Discov doi: 10.1158/2159-8290. CD-15-0412 [epub ahead of print on May 23, 2015]
-
(2015)
Cancer Discov
-
-
Murugaesu, N.1
Wilson, G.A.2
Birkbak, N.J.3
-
16
-
-
84936890500
-
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
-
Yates LR, Gerstung M, Knappskog S, et al: Subclonal diversification of primary breast cancer revealed by multiregion sequencing. Nat Med 21:751-759, 2015
-
(2015)
Nat Med
, vol.21
, pp. 751-759
-
-
Yates, L.R.1
Gerstung, M.2
Knappskog, S.3
-
17
-
-
84905370049
-
Tracking genomic cancer evolution for precision medicine: The lung TRACERx study
-
Jamal-Hanjani M, Hackshaw A, Ngai Y, et al: Tracking genomic cancer evolution for precision medicine: The lung TRACERx study. PLoS Biol 12:e1001906, 2014
-
(2014)
PLoS Biol
, vol.12
, pp. e1001906
-
-
Jamal-Hanjani, M.1
Hackshaw, A.2
Ngai, Y.3
-
18
-
-
84947461588
-
Intratumoral heterogeneity of ALK-rearranged and ALK/EGFR coaltered lung adenocarcinoma
-
Cai W, Lin D, Wu C, et al: Intratumoral heterogeneity of ALK-rearranged and ALK/EGFR coaltered lung adenocarcinoma. J Clin Oncol 33:3701-3709, 2015
-
(2015)
J Clin Oncol
, vol.33
, pp. 3701-3709
-
-
Cai, W.1
Lin, D.2
Wu, C.3
-
19
-
-
84864231379
-
Comparison of reverse transcription-polymerase chain reaction, immunohistochemistry, and fluorescence in situ hybridization methodologies for detection of echinoderm microtubule-associated proteinlike 4-anaplastic lymphoma kinase fusion-positive non-small-cell lung carcinoma: Implications for optimal clinical testing
-
Wallander ML, Geiersbach KB, Tripp SR, et al: Comparison of reverse transcription-polymerase chain reaction, immunohistochemistry, and fluorescence in situ hybridization methodologies for detection of echinoderm microtubule-associated proteinlike 4-anaplastic lymphoma kinase fusion-positive non-small-cell lung carcinoma: Implications for optimal clinical testing. Arch Pathol Lab Med 136:796-803, 2012
-
(2012)
Arch Pathol Lab Med
, vol.136
, pp. 796-803
-
-
Wallander, M.L.1
Geiersbach, K.B.2
Tripp, S.R.3
-
20
-
-
84874023763
-
Combined use of ALK immunohistochemistry and FISH for optimal detection of ALK-rearranged lung adenocarcinomas
-
Sholl LM, Weremowicz S, Gray SW, et al: Combined use of ALK immunohistochemistry and FISH for optimal detection of ALK-rearranged lung adenocarcinomas. J Thorac Oncol 8:322-328, 2013
-
(2013)
J Thorac Oncol
, vol.8
, pp. 322-328
-
-
Sholl, L.M.1
Weremowicz, S.2
Gray, S.W.3
-
21
-
-
79953118839
-
Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
-
Sequist LV, Waltman BA, Dias-Santagata D, et al: Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med 3:75ra26, 2011
-
(2011)
Sci Transl Med
, vol.3
, pp. 75ra26
-
-
Sequist, L.V.1
Waltman, B.A.2
Dias-Santagata, D.3
-
22
-
-
84928254065
-
Clonal status of actionable driver events and the timing of mutational processes in cancer evolution
-
McGranahan N, Favero F, de Bruin EC, et al: Clonal status of actionable driver events and the timing of mutational processes in cancer evolution. Sci Transl Med 7:283ra54, 2015
-
(2015)
Sci Transl Med
, vol.7
, pp. 283ra54
-
-
McGranahan, N.1
Favero, F.2
De Bruin, E.C.3
-
23
-
-
84863011443
-
Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer
-
Su KY, Chen HY, Li KC, et al: Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer. J Clin Oncol 30:433-440, 2012
-
(2012)
J Clin Oncol
, vol.30
, pp. 433-440
-
-
Su, K.Y.1
Chen, H.Y.2
Li, K.C.3
-
24
-
-
84901636202
-
A comparison of immunohistochemical assays and FISH in detecting the ALK translocation in diagnostic histological and cytological lung tumor material
-
Le Quesne J, Maurya M, Yancheva SG, et al: A comparison of immunohistochemical assays and FISH in detecting the ALK translocation in diagnostic histological and cytological lung tumor material. J Thorac Oncol 9:769-774, 2014
-
(2014)
J Thorac Oncol
, vol.9
, pp. 769-774
-
-
Le Quesne, J.1
Maurya, M.2
Yancheva, S.G.3
-
25
-
-
84862757952
-
Evolutionary dynamics of carcinogenesis and why targeted therapy does not work
-
Gillies RJ, Verduzco D, Gatenby RA: Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. Nat Rev Cancer 12:487-493, 2012
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 487-493
-
-
Gillies, R.J.1
Verduzco, D.2
Gatenby, R.A.3
|