-
1
-
-
77958478674
-
Rational, biologically based treatment of EGFRmutant non-small cell lung cancer
-
Pao W, Chmielecki J. Rational, biologically based treatment of EGFRmutant non-small cell lung cancer. Nat Rev Cancer. 2010;10(11):760-774.
-
(2010)
Nat Rev Cancer.
, vol.10
, Issue.11
, pp. 760-774
-
-
Pao, W.1
Chmielecki, J.2
-
2
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
DOI 10.1038/nature05945, PII NATURE05945
-
Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small cell lung cancer. Nature. 2007;448(7153): 561-566. (Pubitemid 47206930)
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
Takada, S.4
Yamashita, Y.5
Ishikawa, S.6
Fujiwara, S.-I.7
Watanabe, H.8
Kurashina, K.9
Hatanaka, H.10
Bando, M.11
Ohno, S.12
Ishikawa, Y.13
Aburatani, H.14
Niki, T.15
Sohara, Y.16
Sugiyama, Y.17
Mano, H.18
-
3
-
-
48549098388
-
Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer
-
Choi YL, Takeuchi K, Soda M, et al. Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer. Cancer Res. 2008; 68(13):4971-4976.
-
(2008)
Cancer Res.
, vol.68
, Issue.13
, pp. 4971-4976
-
-
Choi, Y.L.1
Takeuchi, K.2
Soda, M.3
-
4
-
-
57349113565
-
Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts
-
Takeuchi K, Choi YL, Soda M, et al. Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts. Clin Cancer Res. 2008;14(20):6618- 6624.
-
(2008)
Clin Cancer Res.
, vol.14
, Issue.20
, pp. 6618-6624
-
-
Takeuchi, K.1
Choi, Y.L.2
Soda, M.3
-
5
-
-
63949086127
-
KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer
-
Takeuchi K, Choi YL, Togashi Y, et al. KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res. 2009;15(9):3143-3149.
-
(2009)
Clin Cancer Res.
, vol.15
, Issue.9
, pp. 3143-3149
-
-
Takeuchi, K.1
Choi, Y.L.2
Togashi, Y.3
-
6
-
-
48249114422
-
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
-
Koivunen JP, Mermel C, Zejnullahu K, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res. 2008;14(13): 4275-4283.
-
(2008)
Clin Cancer Res.
, vol.14
, Issue.13
, pp. 4275-4283
-
-
Koivunen, J.P.1
Mermel, C.2
Zejnullahu, K.3
-
7
-
-
65249095599
-
The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
-
Wong DW, Leung EL, So KK, et al. The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer. 2009;115(8):1723-1733.
-
(2009)
Cancer.
, vol.115
, Issue.8
, pp. 1723-1733
-
-
Wong, D.W.1
Leung, E.L.2
So, K.K.3
-
8
-
-
79955656623
-
Exon scanning by reverse transcriptasepolymerase chain reaction for detection of known and novel EML4-ALK fusion variants in non-small cell lung cancer
-
Sanders HR, Li HR, Bruey JM, et al. Exon scanning by reverse transcriptasepolymerase chain reaction for detection of known and novel EML4-ALK fusion variants in non-small cell lung cancer. Cancer Genet. 2011;204(1):45-52.
-
(2011)
Cancer Genet.
, vol.204
, Issue.1
, pp. 45-52
-
-
Sanders, H.R.1
Li, H.R.2
Bruey, J.M.3
-
9
-
-
58149382583
-
A mouse model for EML4-ALK- positive lung cancer
-
Soda M, Takada S, Takeuchi K, et al. A mouse model for EML4-ALK- positive lung cancer. Proc Natl Acad Sci U S A. 2008;105(50):19893-19897.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, Issue.50
, pp. 19893-19897
-
-
Soda, M.1
Takada, S.2
Takeuchi, K.3
-
10
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small cell lung cancer. N Engl J Med. 2010;363(18):1693-1703.
-
(2010)
N Engl J Med.
, vol.363
, Issue.18
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
-
11
-
-
70349336416
-
Clinical features and outcome of patients with non-small cell lung cancer who harbor EML4-ALK
-
Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non-small cell lung cancer who harbor EML4-ALK. J Clin Oncol. 2009;27(26):4247-4253.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.26
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
-
12
-
-
78349237453
-
Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment
-
Camidge DR, Kono SA, Flacco A, et al. Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment. Clin Cancer Res. 2010; 16(22):5581-5590.
-
(2010)
Clin Cancer Res.
, vol.16
, Issue.22
, pp. 5581-5590
-
-
Camidge, D.R.1
Kono, S.A.2
Flacco, A.3
-
13
-
-
77954399760
-
Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression
-
Zhang X, Zhang S, Yang X, et al. Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression. Mol Cancer. 2010;9:188.
-
(2010)
Mol Cancer.
, vol.9
, pp. 188
-
-
Zhang, X.1
Zhang, S.2
Yang, X.3
-
14
-
-
69349083935
-
Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
-
Rodig SJ, Mino-Kenudson M, Dacic S, et al. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res. 2009;15(16):5216-5223.
-
(2009)
Clin Cancer Res.
, vol.15
, Issue.16
, pp. 5216-5223
-
-
Rodig, S.J.1
Mino-Kenudson, M.2
Dacic, S.3
-
15
-
-
84864185669
-
Most ALK-positive lung adenocarcinomas exhibit characteristic histology [abstract]
-
Yoshida A, Tsuta K, Kohno T, et al. Most ALK-positive lung adenocarcinomas exhibit characteristic histology [abstract]. Mod Pathol. 2011;24(suppl 1s): 429A.
-
(2011)
Mod Pathol.
, vol.24
, Issue.SUPPL. 1S
-
-
Yoshida, A.1
Tsuta, K.2
Kohno, T.3
-
16
-
-
37549060017
-
EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
-
Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol. 2008;3(1): 13-17.
-
(2008)
J Thorac Oncol.
, vol.3
, Issue.1
, pp. 13-17
-
-
Inamura, K.1
Takeuchi, K.2
Togashi, Y.3
-
17
-
-
74249123333
-
ALK gene rearrangements: A new therapeutic target in a molecularly defined subset of non-small cell lung cancer
-
Solomon B, Varella-Garcia M, Camidge DR. ALK gene rearrangements: a new therapeutic target in a molecularly defined subset of non-small cell lung cancer. J Thorac Oncol. 2009;4(12):1450-1454.
-
(2009)
J Thorac Oncol.
, vol.4
, Issue.12
, pp. 1450-1454
-
-
Solomon, B.1
Varella-Garcia, M.2
Camidge, D.R.3
-
18
-
-
70349342712
-
EML4-ALK: Honing in on a new target in non-small cell lung cancer
-
Horn L, Pao W. EML4-ALK: honing in on a new target in non-small cell lung cancer. J Clin Oncol. 2009;27(26):4232-4235.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.26
, pp. 4232-4235
-
-
Horn, L.1
Pao, W.2
-
19
-
-
44849126091
-
Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors
-
McDermott U, Iafrate AJ, Gray NS, et al. Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors. Cancer Res. 2008;68(9):3389-3395.
-
(2008)
Cancer Res.
, vol.68
, Issue.9
, pp. 3389-3395
-
-
McDermott, U.1
Iafrate, A.J.2
Gray, N.S.3
-
20
-
-
33645164077
-
Epidermal growth factor receptor gene amplification and protein expression in glioblastoma multiforme: Prognostic significance and relationship to other prognostic factors
-
Layfield LJ, Willmore C, Tripp S, Jones C, Jensen RL. Epidermal growth factor receptor gene amplification and protein expression in glioblastoma multiforme: prognostic significance and relationship to other prognostic factors. Appl Immunohistochem Mol Morphol. 2006;14(1):91-96.
-
(2006)
Appl Immunohistochem Mol Morphol.
, vol.14
, Issue.1
, pp. 91-96
-
-
Layfield, L.J.1
Willmore, C.2
Tripp, S.3
Jones, C.4
Jensen, R.L.5
-
21
-
-
59649127007
-
EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues
-
Martelli MP, Sozzi G, Hernandez L, et al. EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues. Am J Pathol. 2009; 174(2):661-670.
-
(2009)
Am J Pathol.
, vol.174
, Issue.2
, pp. 661-670
-
-
Martelli, M.P.1
Sozzi, G.2
Hernandez, L.3
-
22
-
-
67650441507
-
Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas
-
Boland JM, Erdogan S, Vasmatzis G, et al. Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas. Hum Pathol. 2009;40(8):1152-1158.
-
(2009)
Hum Pathol.
, vol.40
, Issue.8
, pp. 1152-1158
-
-
Boland, J.M.1
Erdogan, S.2
Vasmatzis, G.3
-
23
-
-
77149130499
-
Clinicopathologic features of non-small cell lung cancer with EML4-ALK fusion gene
-
Takahashi T, Sonobe M, Kobayashi M, et al. Clinicopathologic features of non-small cell lung cancer with EML4-ALK fusion gene. Ann Surg Oncol. 2010; 17(3):889-897.
-
(2010)
Ann Surg Oncol.
, vol.17
, Issue.3
, pp. 889-897
-
-
Takahashi, T.1
Sonobe, M.2
Kobayashi, M.3
-
24
-
-
77649091118
-
A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry
-
Mino-Kenudson M, Chirieac LR, Law K, et al. A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry. Clin Cancer Res. 2010;16(5):1561-1571.
-
(2010)
Clin Cancer Res.
, vol.16
, Issue.5
, pp. 1561-1571
-
-
Mino-Kenudson, M.1
Chirieac, L.R.2
Law, K.3
-
25
-
-
84864201424
-
Immunohistochemical analysis of ALK fusioen-positive lung cancers: Correlation with FISH, molecular findings and morphology [abstract 1799]
-
Saab ST LC, Hollis CJ, Ashwini Y, Ji H, Pao W, Gonzalez A. Immunohistochemical analysis of ALK fusion-positive lung cancers: correlation with FISH, molecular findings and morphology [abstract 1799]. Mod Pathol. 2011;24(suppl 1s):423A.
-
(2011)
Mod Pathol.
, vol.24
, Issue.SUPPL. 1S
-
-
Saab, S.T.L.C.1
Hollis, C.J.2
Ashwini, Y.3
Ji, H.4
Pao, W.5
Gonzalez, A.6
-
26
-
-
40149109522
-
EML4-ALK fusion lung cancer: A rare acquired event
-
DOI 10.1593/NEO.07878
-
Perner S, Wagner PL, Demichelis F, et al. EML4-ALK fusion lung cancer: a rare acquired event. Neoplasia. 2008;10(3):298-302. (Pubitemid 351328588)
-
(2008)
Neoplasia
, vol.10
, Issue.3
, pp. 298-302
-
-
Perner, S.1
Wagner, P.L.2
Demichelis, F.3
Mehra, R.4
LaFargue, C.J.5
Moss, B.J.6
Arbogast, S.7
Soltermann, A.8
Weder, W.9
Giordano, T.J.10
Beer, D.G.11
Rickman, D.S.12
Chinnaiyan, A.M.13
Moch, H.14
Rubin, M.A.15
-
27
-
-
70349510460
-
Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers
-
Lin E, Li L, Guan Y, et al. Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers. Mol Cancer Res. 2009;7(9): 1466-1476.
-
(2009)
Mol Cancer Res.
, vol.7
, Issue.9
, pp. 1466-1476
-
-
Lin, E.1
Li, L.2
Guan, Y.3
|