메뉴 건너뛰기




Volumn 99, Issue 12, 2008, Pages 2349-2355

Non-solid oncogenes in solid tumors: EML4-ALK fusion genes in lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; ECHINODERM MICROTUBULE ASSOCIATED PROTEIN LIKE 4 ANAPLASTIC LYMPHOMA KINASE; HYBRID PROTEIN; ISOPROTEIN; MESSENGER RNA; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

EID: 57349100409     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.00972.x     Document Type: Review
Times cited : (204)

References (71)
  • 2
    • 14644425319 scopus 로고    scopus 로고
    • Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia
    • Ren R. Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia. Nat Rev Cancer 2005; 5: 172-83.
    • (2005) Nat Rev Cancer , vol.5 , pp. 172-183
    • Ren, R.1
  • 3
    • 0033519238 scopus 로고    scopus 로고
    • The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity
    • Li S, Ilaria RL Jr, Million RP, Daley GQ, Van Etten RA. The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity. J Exp Med 1999; 189: 1399-412.
    • (1999) J Exp Med , vol.189 , pp. 1399-1412
    • Li, S.1    Ilaria Jr., R.L.2    Million, R.P.3    Daley, G.Q.4    Van Etten, R.A.5
  • 4
    • 0032533257 scopus 로고    scopus 로고
    • Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow
    • Pear WS, Miller JP, Xu L et al. Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow. Blood 1998; 92: 3780-92.
    • (1998) Blood , vol.92 , pp. 3780-3792
    • Pear, W.S.1    Miller, J.P.2    Xu, L.3
  • 5
    • 2142802114 scopus 로고    scopus 로고
    • Monitoring bcr-abl by polymerase chain reaction in the treatment of chronic myeloid leukemia
    • Oehler VG, Radich JP. Monitoring bcr-abl by polymerase chain reaction in the treatment of chronic myeloid leukemia. Curr Oncol Rep 2003; 5: 426-35.
    • (2003) Curr Oncol Rep , vol.5 , pp. 426-435
    • Oehler, V.G.1    Radich, J.P.2
  • 6
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001;344: 1031-7.
    • (2001) N Engl J Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3
  • 7
    • 33845444046 scopus 로고    scopus 로고
    • Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
    • Druker BJ, Guilhot F, O'Brien SG et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 2006; 355: 2408-17.
    • (2006) N Engl J Med , vol.355 , pp. 2408-2417
    • Druker, B.J.1    Guilhot, F.2    O'Brien, S.G.3
  • 8
    • 0034125650 scopus 로고    scopus 로고
    • Recurrent chromosome aberrations in cancer
    • Mitelman F. Recurrent chromosome aberrations in cancer. Mutat Res 2000; 462: 247-53.
    • (2000) Mutat Res , vol.462 , pp. 247-253
    • Mitelman, F.1
  • 10
    • 21744437101 scopus 로고    scopus 로고
    • Prevalence estimates of recurrent balanced cytogenetic aberrations and gene fusions in unselected patients with neoplastic disorders
    • Mitelman F, Mertens F, Johansson B. Prevalence estimates of recurrent balanced cytogenetic aberrations and gene fusions in unselected patients with neoplastic disorders. Genes Chromosomes Cancer 2005; 43: 350-66.
    • (2005) Genes Chromosomes Cancer , vol.43 , pp. 350-366
    • Mitelman, F.1    Mertens, F.2    Johansson, B.3
  • 11
    • 1842535882 scopus 로고    scopus 로고
    • Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer
    • Mitelman F, Johansson B, Mertens F. Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer. Nat Genet 2004; 36: 331-4.
    • (2004) Nat Genet , vol.36 , pp. 331-334
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 12
    • 33947581390 scopus 로고    scopus 로고
    • The impact of translocations and gene fusions on cancer causation
    • Mitelman F, Johansson B, Mertens F. The impact of translocations and gene fusions on cancer causation. Nat Rev Cancer 2007; 7: 233-45.
    • (2007) Nat Rev Cancer , vol.7 , pp. 233-245
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 13
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • Soda M, Choi YL, Enomoto M et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007; 448: 561-6.
    • (2007) Nature , vol.448 , pp. 561-566
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3
  • 14
    • 48549098388 scopus 로고    scopus 로고
    • Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer
    • Choi YL, Takeuchi K, Soda M et al. Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer. Cancer Res 2008; 68: 4971-6.
    • (2008) Cancer Res , vol.68 , pp. 4971-4976
    • Choi, Y.L.1    Takeuchi, K.2    Soda, M.3
  • 15
    • 37549060017 scopus 로고    scopus 로고
    • EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
    • Inamura K, Takeuchi K, Togashi Y et al. EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol 2008; 3: 13-17.
    • (2008) J Thorac Oncol , vol.3 , pp. 13-17
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3
  • 16
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, Rhodes DR, Perner S et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005; 310: 644-8.
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1    Rhodes, D.R.2    Perner, S.3
  • 17
    • 34547642493 scopus 로고    scopus 로고
    • Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
    • Tomlins SA, Laxman B, Dhanasekaran SM et al. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 2007; 448: 595-9.
    • (2007) Nature , vol.448 , pp. 595-599
    • Tomlins, S.A.1    Laxman, B.2    Dhanasekaran, S.M.3
  • 19
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-39.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 20
  • 21
    • 37249003928 scopus 로고    scopus 로고
    • Oncogene addiction: Setting the stage for molecularly targeted cancer therapy
    • Sharma SV, Settleman J. Oncogene addiction: Setting the stage for molecularly targeted cancer therapy. Genes Dev 2007; 21: 3214-31.
    • (2007) Genes Dev , vol.21 , pp. 3214-3231
    • Sharma, S.V.1    Settleman, J.2
  • 22
    • 0020046441 scopus 로고
    • Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells
    • Goldfarb M, Shimizu K, Perucho M, Wigler M. Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells. Nature 1982; 296: 404-9.
    • (1982) Nature , vol.296 , pp. 404-409
    • Goldfarb, M.1    Shimizu, K.2    Perucho, M.3    Wigler, M.4
  • 23
    • 0026316096 scopus 로고
    • Growth factors and cancer
    • Aaronson SA. Growth factors and cancer. Science 1991; 254: 1146-53.
    • (1991) Science , vol.254 , pp. 1146-1153
    • Aaronson, S.A.1
  • 24
    • 20544447126 scopus 로고    scopus 로고
    • Retroviral expression screening of oncogenes in natural killer cell leukemia
    • Choi YL, Moriuchi R, Osawa M et al. Retroviral expression screening of oncogenes in natural killer cell leukemia. Leuk Res 2005; 29: 943-9.
    • (2005) Leuk Res , vol.29 , pp. 943-949
    • Choi, Y.L.1    Moriuchi, R.2    Osawa, M.3
  • 25
    • 27744570032 scopus 로고    scopus 로고
    • Transforming activity of the lymphotoxin-β receptor revealed by expression screening
    • Fujiwara S, Yamashita Y, Choi YL et al. Transforming activity of the lymphotoxin-β receptor revealed by expression screening. Biochem Biophys Res Commun 2005; 338: 1256-62.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 1256-1262
    • Fujiwara, S.1    Yamashita, Y.2    Choi, Y.L.3
  • 26
    • 25144464369 scopus 로고    scopus 로고
    • Retroviral expression screening of oncogenes in pancreatic ductal carcinoma
    • Kisanuki H, Choi YL, Wada T et al. Retroviral expression screening of oncogenes in pancreatic ductal carcinoma. Eur J Cancer 2005; 41: 2170-5.
    • (2005) Eur J Cancer , vol.41 , pp. 2170-2175
    • Kisanuki, H.1    Choi, Y.L.2    Wada, T.3
  • 27
    • 33845208243 scopus 로고    scopus 로고
    • Identification of a constitutively active mutant of JAK3 by retroviral expression screening
    • Choi YL, Kaneda R, Wada T et al. Identification of a constitutively active mutant of JAK3 by retroviral expression screening. Leuk Res 2007; 31: 203-9.
    • (2007) Leuk Res , vol.31 , pp. 203-209
    • Choi, Y.L.1    Kaneda, R.2    Wada, T.3
  • 28
    • 34547440147 scopus 로고    scopus 로고
    • Transforming activity of purinergic receptor P2Y, G protein coupled, 8 revealed by retroviral expression screening
    • Fujiwara S, Yamashita Y, Choi YL et al. Transforming activity of purinergic receptor P2Y, G protein coupled, 8 revealed by retroviral expression screening. Leuk Lymphoma 2007; 48: 978-86.
    • (2007) Leuk Lymphoma , vol.48 , pp. 978-986
    • Fujiwara, S.1    Yamashita, Y.2    Choi, Y.L.3
  • 29
    • 33947663549 scopus 로고    scopus 로고
    • Transforming activity of purinergic receptor P2Y, G-protein coupled, 2 revealed by retroviral expression screening
    • Hatanaka H, Takada S, Choi YL et al. Transforming activity of purinergic receptor P2Y, G-protein coupled, 2 revealed by retroviral expression screening. Biochem Biophys Res Commun 2007; 356: 723-6.
    • (2007) Biochem Biophys Res Commun , vol.356 , pp. 723-726
    • Hatanaka, H.1    Takada, S.2    Choi, Y.L.3
  • 31
    • 6344262173 scopus 로고    scopus 로고
    • An alternative transcript derived from the trio locus encodes a guanosine nucleotide exchange factor with mouse cell-transforming potential
    • Yoshizuka N, Moriuchi R, Mori T et al. An alternative transcript derived from the trio locus encodes a guanosine nucleotide exchange factor with mouse cell-transforming potential. J Biol Chem 2004; 279: 43 998-4004.
    • (2004) J Biol Chem , vol.279 , pp. 43998-44004
    • Yoshizuka, N.1    Moriuchi, R.2    Mori, T.3
  • 32
    • 42949171158 scopus 로고    scopus 로고
    • American Cancer Society. [Cited 18 October, 2008.]Available from URL
    • American Cancer Society. Global Cancer Facts and Figures 2007. [Cited 18 October, 2008.]Available from URL: http://www.cancer.org/downloads/STT/ Global_Facts_and_Figures_2007_rev2.pdf.
    • (2007) Global Cancer Facts and Figures
  • 33
    • 20044364940 scopus 로고    scopus 로고
    • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
    • Shigematsu H, Lin L, Takahashi T et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005; 97: 339-46.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 339-346
    • Shigematsu, H.1    Lin, L.2    Takahashi, T.3
  • 34
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
    • Schiller JH, Harrington D, Belani CP et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med 2002; 346: 92-8.
    • (2002) N Engl J Med , vol.346 , pp. 92-98
    • Schiller, J.H.1    Harrington, D.2    Belani, C.P.3
  • 36
    • 0031008896 scopus 로고    scopus 로고
    • ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)
    • Morris SW, Naeve C, Mathew P et al. ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK). Oncogene 1997; 14: 2175-88.
    • (1997) Oncogene , vol.14 , pp. 2175-2188
    • Morris, S.W.1    Naeve, C.2    Mathew, P.3
  • 37
    • 0028198206 scopus 로고
    • Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
    • Morris SW, Kirstein MN, Valentine MB et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 1994; 263: 1281-4.
    • (1994) Science , vol.263 , pp. 1281-1284
    • Morris, S.W.1    Kirstein, M.N.2    Valentine, M.B.3
  • 38
    • 0028275645 scopus 로고
    • Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3
    • Shiota M, Fujimoto J, Semba T, Satoh H, Yamamoto T, Mori S. Hyperphosphorylation of a novel 80.kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3. Oncogene 1994; 9: 1567-74.
    • (1994) Oncogene , vol.9 , pp. 1567-1574
    • Shiota, M.1    Fujimoto, J.2    Semba, T.3    Satoh, H.4    Yamamoto, T.5    Mori, S.6
  • 39
    • 32644442671 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cells
    • Wan W, Albom MS, Lu L et al. Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cells. Blood 2006; 107: 1617-23.
    • (2006) Blood , vol.107 , pp. 1617-1623
    • Wan, W.1    Albom, M.S.2    Lu, L.3
  • 40
    • 33846110366 scopus 로고    scopus 로고
    • Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK
    • Galkin AV, Melnick JS, Kim S et al. Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK. Proc Natl Acad Sci USA 2007; 104: 270-5.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 270-275
    • Galkin, A.V.1    Melnick, J.S.2    Kim, S.3
  • 41
    • 2342635959 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase proteins in growth control and cancer
    • Pulford K, Morris SW, Turturro F. Anaplastic lymphoma kinase proteins in growth control and cancer. J Cell Physiol 2004; 199: 330-58.
    • (2004) J Cell Physiol , vol.199 , pp. 330-358
    • Pulford, K.1    Morris, S.W.2    Turturro, F.3
  • 42
    • 15444339209 scopus 로고    scopus 로고
    • A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia
    • Lacronique V, Boureux A, Valle VD et al. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science 1997; 278: 1309-12.
    • (1997) Science , vol.278 , pp. 1309-1312
    • Lacronique, V.1    Boureux, A.2    Valle, V.D.3
  • 43
    • 47649105190 scopus 로고    scopus 로고
    • EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas
    • Shinmura K, Kageyama S, Tao H et al. EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas. Lung Cancer 2008; 61: 163-9.
    • (2008) Lung Cancer , vol.61 , pp. 163-169
    • Shinmura, K.1    Kageyama, S.2    Tao, H.3
  • 44
    • 57349114544 scopus 로고    scopus 로고
    • EML4-ALK is a new oncogene in non-small cell lung carcinoma showing wild-type EGFR and K-RAS from non-smokers
    • 12-16 April San Diego, AACR (Philadelphia): (poster #LB-62)
    • Wong DD-S, So KK-T, Leung EL-H et al. EML4-ALK is a new oncogene in non-small cell lung carcinoma showing wild-type EGFR and K-RAS from non-smokers. American Association of Cancer Research Annual Meeting 12-16 April, 2008, San Diego, AACR (Philadelphia): (poster #LB-62).
    • (2008) American Association of Cancer Research Annual Meeting
    • Wong, D.D.-S.1    So, K.K.-T.2    Leung, E.L.-H.3
  • 45
    • 48249114422 scopus 로고    scopus 로고
    • EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
    • Koivunen JP, Mermel C, Zejnullahu K et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008; 14: 4275-83.
    • (2008) Clin Cancer Res , vol.14 , pp. 4275-4283
    • Koivunen, J.P.1    Mermel, C.2    Zejnullahu, K.3
  • 46
    • 57349113565 scopus 로고    scopus 로고
    • Multiplex RT-PCR screening for EML4-ALK fusion transcripts
    • Takeuchi K, Choi YL, Soda M et al. Multiplex RT-PCR screening for EML4-ALK fusion transcripts. Clin Cancer Res 2008; 14: 6618-24.
    • (2008) Clin Cancer Res , vol.14 , pp. 6618-6624
    • Takeuchi, K.1    Choi, Y.L.2    Soda, M.3
  • 47
    • 40149109522 scopus 로고    scopus 로고
    • EML4-ALK fusion lung cancer: A rare acquired event
    • Perner S, Wagner PL, Demichelis F et al. EML4-ALK fusion lung cancer: A rare acquired event. Neoplasia 2008; 10: 298-302.
    • (2008) Neoplasia , vol.10 , pp. 298-302
    • Perner, S.1    Wagner, P.L.2    Demichelis, F.3
  • 48
    • 0032752921 scopus 로고    scopus 로고
    • Detection of t(2;5) in anaplastic large cell lymphoma: Comparison of immunohistochemical studies, FISH, and RT-PCR in paraffin-embedded tissue
    • Cataldo KA, Jalal SM, Law ME et al. Detection of t(2;5) in anaplastic large cell lymphoma: Comparison of immunohistochemical studies, FISH, and RT-PCR in paraffin-embedded tissue. Am J Surg Pathol 1999; 23: 1386-92.
    • (1999) Am J Surg Pathol , vol.23 , pp. 1386-1392
    • Cataldo, K.A.1    Jalal, S.M.2    Law, M.E.3
  • 49
    • 33646481086 scopus 로고    scopus 로고
    • Fusion tyrosine kinase mediated signalling pathways in the transformation of haematopoietic cells
    • Turner SD, Alexander DR. Fusion tyrosine kinase mediated signalling pathways in the transformation of haematopoietic cells. Leukemia 2006; 20: 572-82.
    • (2006) Leukemia , vol.20 , pp. 572-582
    • Turner, S.D.1    Alexander, D.R.2
  • 50
    • 38949110654 scopus 로고    scopus 로고
    • Roles for deregulated receptor tyrosine kinases and their downstream signaling molecules in hematologic malignancies
    • Matsumura I, Mizuki M, Kanakura Y. Roles for deregulated receptor tyrosine kinases and their downstream signaling molecules in hematologic malignancies. Cancer Sci 2008; 99: 479-85.
    • (2008) Cancer Sci , vol.99 , pp. 479-485
    • Matsumura, I.1    Mizuki, M.2    Kanakura, Y.3
  • 51
    • 0030934862 scopus 로고    scopus 로고
    • Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis
    • Bischof D, Pulford K, Mason DY, Morris SW. Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis. Mol Cell Biol 1997; 17: 2312-25.
    • (1997) Mol Cell Biol , vol.17 , pp. 2312-2325
    • Bischof, D.1    Pulford, K.2    Mason, D.Y.3    Morris, S.W.4
  • 52
    • 0141998608 scopus 로고    scopus 로고
    • Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers
    • Lee HH, Norris A, Weiss JB, Frasch M. Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers. Nature 2003; 425: 507-12.
    • (2003) Nature , vol.425 , pp. 507-512
    • Lee, H.H.1    Norris, A.2    Weiss, J.B.3    Frasch, M.4
  • 53
    • 0035907231 scopus 로고    scopus 로고
    • Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin
    • Stoica GE, Kuo A, Aigner A et al. Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin. J Biol Chem 2001; 276: 16 772-9.
    • (2001) J Biol Chem , vol.276 , pp. 16772-16779
    • Stoica, G.E.1    Kuo, A.2    Aigner, A.3
  • 54
    • 0037184128 scopus 로고    scopus 로고
    • Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types
    • Stoica GE, Kuo A, Powers C et al. Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types. J Biol Chem 2002; 277: 35 990-8.
    • (2002) J Biol Chem , vol.277 , pp. 35990-35998
    • Stoica, G.E.1    Kuo, A.2    Powers, C.3
  • 55
    • 0031055562 scopus 로고    scopus 로고
    • Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1
    • Pulford K, Lamant L, Morris SW et al. Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1. Blood 1997; 89: 1394-404.
    • (1997) Blood , vol.89 , pp. 1394-1404
    • Pulford, K.1    Lamant, L.2    Morris, S.W.3
  • 56
    • 0031035052 scopus 로고    scopus 로고
    • Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system
    • Iwahara T, Fujimoto J, Wen D et al. Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system. Oncogene 1997; 14: 439-49.
    • (1997) Oncogene , vol.14 , pp. 439-449
    • Iwahara, T.1    Fujimoto, J.2    Wen, D.3
  • 57
    • 0029834975 scopus 로고    scopus 로고
    • 6B4 proteoglycan/phosphacan, an extracellular variant of receptor-like protein-tyrosine phosphatase zeta/RPTPbeta, binds pleiotrophin/ heparin-binding growth-associated molecule (HB-GAM)
    • Maeda N, Nishiwaki T, Shintani T, Hamanaka H, Noda M. 6B4 proteoglycan/ phosphacan, an extracellular variant of receptor-like protein-tyrosine phosphatase zeta/RPTPbeta, binds pleiotrophin/heparin-binding growth-associated molecule (HB-GAM). J Biol Chem 1996; 271: 21 446-52.
    • (1996) J Biol Chem , vol.271 , pp. 21446-21452
    • Maeda, N.1    Nishiwaki, T.2    Shintani, T.3    Hamanaka, H.4    Noda, M.5
  • 58
    • 0028216755 scopus 로고
    • Isolation of a neuronal cell surface receptor of heparin binding growth-associated molecule (HB-GAM). Identification as N-syndecan (syndecan-3)
    • Raulo E, Chernousov MA, Carey DJ, Nolo R, Rauvala H. Isolation of a neuronal cell surface receptor of heparin binding growth-associated molecule (HB-GAM). Identification as N-syndecan (syndecan-3). J Biol Chem 1994; 269: 12 999-3004.
    • (1994) J Biol Chem , vol.269 , pp. 12999-13004
    • Raulo, E.1    Chernousov, M.A.2    Carey, D.J.3    Nolo, R.4    Rauvala, H.5
  • 59
    • 0030809095 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer of NPM-ALK causes lymphoid malignancy in mice
    • Kuefer MU, Look AT, Pulford K et al. Retrovirus-mediated gene transfer of NPM-ALK causes lymphoid malignancy in mice. Blood 1997; 90: 2901-10.
    • (1997) Blood , vol.90 , pp. 2901-2910
    • Kuefer, M.U.1    Look, A.T.2    Pulford, K.3
  • 60
    • 0043091984 scopus 로고    scopus 로고
    • The oncogenic fusion protein nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) induces two distinct malignant phenotypes in a murine retroviral transplantation model
    • Miething C, Grundler R, Fend F et al. The oncogenic fusion protein nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) induces two distinct malignant phenotypes in a murine retroviral transplantation model. Oncogene 2003; 22: 4642-7.
    • (2003) Oncogene , vol.22 , pp. 4642-4647
    • Miething, C.1    Grundler, R.2    Fend, F.3
  • 61
    • 0344441893 scopus 로고    scopus 로고
    • Vav-promoter regulated oncogenic fusion protein NPM-ALK in transgenic mice causes B-cell lymphomas with hyperactive Jun kinase
    • Turner SD, Tooze R, Maclennan K, Alexander DR. Vav-promoter regulated oncogenic fusion protein NPM-ALK in transgenic mice causes B-cell lymphomas with hyperactive Jun kinase. Oncogene 2003; 22: 7750-61.
    • (2003) Oncogene , vol.22 , pp. 7750-7761
    • Turner, S.D.1    Tooze, R.2    Maclennan, K.3    Alexander, D.R.4
  • 62
    • 44849126091 scopus 로고    scopus 로고
    • Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors
    • McDermott U, Iafrate AJ, Gray NS et al. Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors. Cancer Res 2008; 68: 3389-95.
    • (2008) Cancer Res , vol.68 , pp. 3389-3395
    • McDermott, U.1    Iafrate, A.J.2    Gray, N.S.3
  • 63
    • 0034523519 scopus 로고    scopus 로고
    • Transgenic mouse models for lung cancer
    • Zhao B, Magdaleno S, Chua S et al. Transgenic mouse models for lung cancer. Exp Lung Res 2000; 26: 567-79.
    • (2000) Exp Lung Res , vol.26 , pp. 567-579
    • Zhao, B.1    Magdaleno, S.2    Chua, S.3
  • 64
    • 38049097938 scopus 로고    scopus 로고
    • Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling
    • McDermott U, Sharma SV, Dowell L et al. Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. Proc Natl Acad Sci USA 2007; 104: 19 936-41.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 19936-19941
    • McDermott, U.1    Sharma, S.V.2    Dowell, L.3
  • 65
    • 0036860307 scopus 로고    scopus 로고
    • + anaplastic large cell lymphoma ('ALKoma'): The first case with a combination of 'not common' variants
    • + anaplastic large cell lymphoma ('ALKoma'): The first case with a combination of 'not common'variants. Ann Oncol 2002; 13: 1827-32.
    • (2002) Ann Oncol , vol.13 , pp. 1827-1832
    • Ponzoni, M.1    Terreni, M.R.2    Ciceri, F.3
  • 68
    • 0027359443 scopus 로고
    • Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product
    • Furitsu T, Tsujimura T, Tono T et al. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest 1993; 92: 1736-44.
    • (1993) J Clin Invest , vol.92 , pp. 1736-1744
    • Furitsu, T.1    Tsujimura, T.2    Tono, T.3
  • 70
    • 4444319567 scopus 로고    scopus 로고
    • Differential effects of X-ALK fusion proteins on proliferation, transformation, and invasion properties of NIH3T3 cells
    • Armstrong F, Duplantier MM, Trempat P et al. Differential effects of X-ALK fusion proteins on proliferation, transformation, and invasion properties of NIH3T3 cells. Oncogene 2004; 23: 6071-82.
    • (2004) Oncogene , vol.23 , pp. 6071-6082
    • Armstrong, F.1    Duplantier, M.M.2    Trempat, P.3
  • 71
    • 36849065315 scopus 로고    scopus 로고
    • Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
    • Rikova K, Guo A, Zeng Q et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007; 131: 1190-203.
    • (2007) Cell , vol.131 , pp. 1190-1203
    • Rikova, K.1    Guo, A.2    Zeng, Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.