Establishment of the MethyLight Assay for Assessing Aging, Cigarette Smoking, and Alcohol Consumption

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Endo, Kosuke ^a   Li, Jiawei ^a   Nakanishi, Michio ^a   Asada, Takashi ^a   Ikesue, Masahiro ^a   Goto, Yoichi ^a   Fukushima, Yasue ^a   Iwai, Naoharu ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BIOLOGICAL MARKER; DNA;

ADULT; AGED; AGING; ALCOHOL CONSUMPTION; ARTICLE; B LYMPHOCYTE; BLOOD SAMPLING; CELL IMMORTALIZATION; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA METHYLATION; DNA METHYLATION ASSAY; DRINKING BEHAVIOR; FEMALE; GROUPS BY AGE; HEART INFARCTION; HUMAN; HUMAN CELL; JAPANESE (PEOPLE); MALE; METHYLIGHT ASSAY; MIDDLE AGED; PERIPHERAL BLOOD MONONUCLEAR CELL; PREDICTIVE VALUE; RISK FACTOR; SMOKING; VERY ELDERLY; YOUNG ADULT; AGE DISTRIBUTION; BLOOD; DNA SEQUENCE; GENETICS; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

AGE DISTRIBUTION; AGED; AGING; ALCOHOL DRINKING; DNA; DNA METHYLATION; FEMALE; HUMANS; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA; SMOKING;

EID: 84947286067     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/451981     Document Type: Article

References (31)

1. A. Bird"DNA methylation patterns and epigenetic memory"Genes &Development, vol. 16, no. 1, pp. 6-21, 2002
2. K. Shiota"DNAmethylation profiles of CpGislands for cellular differentiation and development in mammals"Cytogenetic and Genome Research, vol. 105, no. 2-4, pp. 325-334, 2004
3. J. C. Mathers, G. Strathdee, and C. L. Relton"Induction of epigenetic alterations by dietary and other environmental factors"in Advances in Genetics, vol. 71, chapter 1, pp. 3-39, Elsevier, 2010
4. S. Bocklandt, W. Lin, M. E. Sehl et al. "Epigenetic predictor of age"PLoS ONE, vol. 6, no. 6, Article ID e14821, 2011
5. L. Tserel, M. Limbach, M. Saare et al. "CpG sites associated with NRP1, NRXN2 and miR-29b-2 are hypomethylated in monocytes during ageing"Immunity and Ageing, vol. 11, article 1, 2014
6. K. W. K. Lee and Z. Pausova"Cigarette smoking and DNA methylation"Frontiers in Genetics, vol. 4, article 132, 2013
7. N. S. Shenker, P. M. Ueland, S. Polidoroet al. "DNAmethylation as a long-term biomarker of exposure to tobacco smoke"Epidemiology, vol. 24, no. 5, pp. 712-716, 2013
8. L. G. Tsaprouni, T.-P. Yang, J. Bell et al. "Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation"Epigenetics, vol. 9, no. 10, pp. 1382-1396, 2014
9. R. A. Philibert, B. Penaluna, T. White et al. "Apilot examination of the genome-wide DNA methylation signatures of subjects entering and exiting short-term alcohol dependence treatment programs"Epigenetics, vol. 9, no. 9, pp. 1212-1219, 2014
10. H. Zhang, F. Wang, H. R. Kranzler et al. "Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes"Human Genetics, vol. 133, no. 9, pp. 1093-1104, 2014
11. S. Horvath"DNA methylation age of human tissues and cell types"Genome Biology, vol. 14, no. 10, article R115, 2013
12. T. M. Rickabaugh, R. M. Baxter, M. Sehl et al. "Acceleration of age-Associated methylation patterns in HIV-1-infected adults"PLoS ONE, vol. 10, no. 3, Article IDe0119201, 2015
13. C. I. Weidner, Q. Lin, C. M. Koch et al. "Aging of blood can be tracked by DNA methylation changes at just three CpG sites"Genome Biology, vol. 15, no. 2, article R24, 2014
14. E. Olkhov-Mitsel, D. Zdravic, K. Kron, T. van der Kwast, N. Fleshner, and B. Bapat"Novel multiplex MethyLight protocol for detection of DNA methylation in patient tissues and bodily fluids"Scientific Reports, vol. 4, article 4432, 2014
15. K. Endo, N. Kito, Y. Fukushima, H. Weng, and N. Iwai"A novel biomarker for acute kidney injury using TaqManbased unmethylated DNA-specific polymerase chain reaction"Biomedical Research, vol. 35, no. 3, pp. 207-213, 2014
16. L. L. Lam, E. Emberly, H. B. Fraser et al. "Factors underlying variable DNA methylation in a human community cohort"Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 2, pp. 17253-17260, 2012
17. C. A. Eads, K. D. Danenberg, K. Kawakami et al. "MethyLight: a high-throughput assay tomeasure DNAmethylation"Nucleic Acids Research, vol. 28, no. 8, article E32, 2000
18. K. Hashimoto, S. Kokubun, E. Itoi, and H. I. Roach"Improved quantification of DNA methylation using methylation-sensitive restriction enzymes and real-time PCR"Epigenetics, vol. 2, no. 2, pp. 86-91, 2007
19. N. Redshaw, J. F. Huggett, M. S. Taylor, C. A. Foy, and A. S. Devonshire"Quantification of epigenetic biomarkers: an evaluation of established and emerging methods for DNA methylation analysis"BMC Genomics, vol. 15, article 1174, 2014
20. R. E. Marioni, S. Shah, A. F. McRae et al. "DNA methylation age of blood predicts all-cause mortality in later life"Genome Biology, vol. 30, pp. 16-25, 2015
21. S. Horvath, P. Garagnani, M. G. Bacalini et al. "Accelerated epigenetic aging in Down syndrome"Aging Cell, vol. 14, pp. 491-495, 2015
22. M. Sugimoto, H. Tahara, T. Ide, and Y. Furuichi"Steps involved in immortalization and tumorigenesis in human Blymphoblastoid cell lines transformed by Epstein-Barr virus"Cancer Research, vol. 64, no. 10, pp. 3361-3364, 2004
23. L. Tserel, R. Kolde, M. Limbach et al. "Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes"Scientific Reports, vol. 5, article 13107, 2015
24. R. A. Philibert, N. Terry, C. Erwin, W. J. Philibert, S. R. Beach, and G. H. Brody"Methylation array data can simultaneously identify individuals and convey protected health information: an unrecognized ethical concern"Clinical Epigenetics, vol. 6, article 28, 2014
25. J. Mimura, M. Ema, K. Sogawa, and Y. Fujii-Kuriyama"Identification of a novel mechanism of regulation of Ah (dioxin) receptor function"Genes and Development, vol. 13, no. 1, pp. 20-25, 1999
26. R. A. Philibert, S. R. H. Beach, andG. H. Brody"Demethylation of the aryl hydrocarbon receptor repressor as a biomarker for nascent smokers"Epigenetics, vol. 7, no. 11, pp. 1331-1338, 2012
27. S. Zeilinger, B. Kühnel, N. Klopp et al. "Tobacco smoking leads to extensive genome-wide changes in DNA methylation"PLoS ONE, vol. 8, no. 5, Article ID e63812, 2013
28. N. L. Benowitz"Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction"Clinical Pharmacology andTherapeutics, vol. 83, no. 4, pp. 531-541, 2008
29. K. Mattsson, K. Kälĺen, A. Rignell-Hydbom et al. "Cotinine validation of self-reported smoking during pregnancy in the Swedish Medical Birth Register"Nicotine &Tobacco Research, 2015
30. P. Cabarcos, I. Alvarez, M. J. Tabernero, and A. M. Bermejo"Determination of direct alcohol markers: a review"Analytical and Bioanalytical Chemistry, vol. 407, no. 17, pp. 4907-4925, 2015
31. S. Kechagias, D. N. Dernroth, A. Blomgren et al. "Phosphatidylethanol comparedwithotherbloodtests as a biomarker of moderate alcohol consumption in healthy volunteers: a prospective randomized study"Alcohol and Alcoholism, vol. 50, no. 4, pp. 399-406, 2015.