메뉴 건너뛰기




Volumn 83, Issue 4, 2008, Pages 531-541

Clinical pharmacology of nicotine: Implications for understanding, preventing, and treating tobacco addiction

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2A6; NICOTINE; NICOTINIC RECEPTOR;

EID: 40949084426     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2008.3     Document Type: Review
Times cited : (419)

References (51)
  • 1
    • 7544249739 scopus 로고    scopus 로고
    • Cigarette smoking and infection
    • Arcavi, L. & Benowitz, N.L. Cigarette smoking and infection. Arch. Intern. Med. 164, 2206-2216 (2004).
    • (2004) Arch. Intern. Med , vol.164 , pp. 2206-2216
    • Arcavi, L.1    Benowitz, N.L.2
  • 2
    • 33646238486 scopus 로고    scopus 로고
    • Effects of smoking on the pharmacokinetics of erlotinib
    • Hamilton, M. et al. Effects of smoking on the pharmacokinetics of erlotinib. Clin. Cancer Res. 12, 2166-2171 (2006).
    • (2006) Clin. Cancer Res , vol.12 , pp. 2166-2171
    • Hamilton, M.1
  • 3
    • 34447551611 scopus 로고    scopus 로고
    • Cigarette smoking and irinotecan treatment: Pharmacokinetic interaction and effects on neutropenia
    • van der Bol, J.M. et al. Cigarette smoking and irinotecan treatment: pharmacokinetic interaction and effects on neutropenia. J. Clin. Oncol. 25, 2719-2726 (2007).
    • (2007) J. Clin. Oncol , vol.25 , pp. 2719-2726
    • van der Bol, J.M.1
  • 5
    • 0041967223 scopus 로고    scopus 로고
    • Cigarette smoking and cardiovascular disease: Pathophysiology and implications for treatment
    • Benowitz, N.L. Cigarette smoking and cardiovascular disease: pathophysiology and implications for treatment. Prog. Cardiovasc. Dis. 46, 91-111 (2003).
    • (2003) Prog. Cardiovasc. Dis , vol.46 , pp. 91-111
    • Benowitz, N.L.1
  • 6
    • 36849058086 scopus 로고    scopus 로고
    • Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction
    • Mineur, Y.S. & Picciotto, M.R. Genetics of nicotinic acetylcholine receptors: relevance to nicotine addiction. Biochem. Pharmacol. 75, 323-333 (2008).
    • (2008) Biochem. Pharmacol , vol.75 , pp. 323-333
    • Mineur, Y.S.1    Picciotto, M.R.2
  • 7
    • 35548930211 scopus 로고    scopus 로고
    • Synaptic plasticity and addiction
    • Kauer, J.A. & Malenka, R.C. Synaptic plasticity and addiction. Nat. Rev. Neurosci. 8, 844-858 (2007).
    • (2007) Nat. Rev. Neurosci , vol.8 , pp. 844-858
    • Kauer, J.A.1    Malenka, R.C.2
  • 8
    • 33846614921 scopus 로고    scopus 로고
    • Damage to the insula disrupts addiction to cigarette smoking
    • Naqvi, N.H., Rudrauf, D., Damasio, H. & Bechara, A. Damage to the insula disrupts addiction to cigarette smoking. Science 315, 531-534 (2007).
    • (2007) Science , vol.315 , pp. 531-534
    • Naqvi, N.H.1    Rudrauf, D.2    Damasio, H.3    Bechara, A.4
  • 9
    • 33646436206 scopus 로고    scopus 로고
    • Clinical significance of tobacco withdrawal
    • Hughes, J.R. Clinical significance of tobacco withdrawal. Nicotine Tob. Res. 8, 153-156 (2006).
    • (2006) Nicotine Tob. Res , vol.8 , pp. 153-156
    • Hughes, J.R.1
  • 10
    • 14144253640 scopus 로고    scopus 로고
    • Metabolism and disposition kinetics of nicotine
    • Hukkanen, J., Jacob, P. III, & Benowitz, N.L. Metabolism and disposition kinetics of nicotine. Pharmacol. Rev. 57, 79-115 (2005).
    • (2005) Pharmacol. Rev , vol.57 , pp. 79-115
    • Hukkanen, J.1    Jacob III, P.2    Benowitz, N.L.3
  • 11
    • 3042563552 scopus 로고    scopus 로고
    • Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity
    • Dempsey, D. et al. Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity. Clin. Pharmacol. Ther. 76, 64-72 (2004).
    • (2004) Clin. Pharmacol. Ther , vol.76 , pp. 64-72
    • Dempsey, D.1
  • 13
    • 13944284575 scopus 로고    scopus 로고
    • Implications of CYP2A6 genetic variation for smoking behaviors and nicotine dependence
    • Malaiyandi, V., Sellers, E.M. & Tyndale, R.F. Implications of CYP2A6 genetic variation for smoking behaviors and nicotine dependence. Clin. Pharmacol. Ther. 77, 145-158 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.77 , pp. 145-158
    • Malaiyandi, V.1    Sellers, E.M.2    Tyndale, R.F.3
  • 15
    • 0345165510 scopus 로고
    • The nature of nicotine addiction
    • Institute of Medicine, eds. Lynch, B.S, Bonnie, R.J, National Academy Press, Washington DC
    • Institute of Medicine. The nature of nicotine addiction. In Growing Up Tobacco Free - Preventing Nicotine Addiction in Children and Youths (eds. Lynch, B.S., Bonnie, R.J.) 28-68 (National Academy Press, Washington DC, 1994).
    • (1994) Growing Up Tobacco Free - Preventing Nicotine Addiction in Children and Youths , pp. 28-68
  • 16
    • 34249314770 scopus 로고    scopus 로고
    • Adolescent vs. adult-onset nicotine self-administration in male rats: Duration of effect and differential nicotinic receptor correlates
    • Levin, E.D. et al. Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates. Neurotoxicol. Teratol. 29, 458-465 (2007).
    • (2007) Neurotoxicol. Teratol , vol.29 , pp. 458-465
    • Levin, E.D.1
  • 17
    • 40949158795 scopus 로고    scopus 로고
    • Department of Health and Human Services PHS. Tobacco use among U.S. racial/ethnic minority groups - African Americans, American Indians and Alaska Natives, Asian Americans and Pacific Islanders, and Hispanics: a report of the surgeon general: USDHHS, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Promotion, Office of Smoking and Health. Government Printing Office, Washington DC, 1998.
    • Department of Health and Human Services PHS. Tobacco use among U.S. racial/ethnic minority groups - African Americans, American Indians and Alaska Natives, Asian Americans and Pacific Islanders, and Hispanics: a report of the surgeon general: USDHHS, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Promotion, Office of Smoking and Health. Government Printing Office, Washington DC, 1998.
  • 18
    • 31344479326 scopus 로고    scopus 로고
    • Ethnic and racial differences in the smoking-related risk of lung cancer
    • Haiman, C.A. et al. Ethnic and racial differences in the smoking-related risk of lung cancer. N. Engl. J. Med. 354, 333-342 (2006).
    • (2006) N. Engl. J. Med , vol.354 , pp. 333-342
    • Haiman, C.A.1
  • 19
    • 0032496880 scopus 로고    scopus 로고
    • Nicotine metabolism and intake in black and white smokers
    • Perez-Stable, E.J., Herrera, B., Jacob, P. III & Benowitz, N.L. Nicotine metabolism and intake in black and white smokers. JAMA 280, 152-156 (1998).
    • (1998) JAMA , vol.280 , pp. 152-156
    • Perez-Stable, E.J.1    Herrera, B.2    Jacob III, P.3    Benowitz, N.L.4
  • 20
    • 33749022524 scopus 로고    scopus 로고
    • Menthol cigarettes, smoking cessation, atherosclerosis, and pulmonary function: The Coronary Artery Risk Development in Young Adults (CARDIA) Study
    • Pletcher, M.J., Hulley, B.J., Houston, T., Kiefe, C.I., Benowitz, N. & Sidney, S. Menthol cigarettes, smoking cessation, atherosclerosis, and pulmonary function: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Arch. Intern. Med. 166, 1915-1922 (2006).
    • (2006) Arch. Intern. Med , vol.166 , pp. 1915-1922
    • Pletcher, M.J.1    Hulley, B.J.2    Houston, T.3    Kiefe, C.I.4    Benowitz, N.5    Sidney, S.6
  • 21
    • 4243146212 scopus 로고    scopus 로고
    • Mentholated cigarette smoking inhibits nicotine metabolism
    • Benowitz, N.L., Herrera, B. & Jacob, P. III. Mentholated cigarette smoking inhibits nicotine metabolism. J. Pharmacol. Exp. Ther. 310, 1208-1215 (2004).
    • (2004) J. Pharmacol. Exp. Ther , vol.310 , pp. 1208-1215
    • Benowitz, N.L.1    Herrera, B.2    Jacob III, P.3
  • 22
    • 0037116614 scopus 로고    scopus 로고
    • Slower metabolism and reduced intake of nicotine from cigarette smoking in Chinese-Americans
    • Benowitz, N.L., Perez-Stable, E.J., Herrera, B. & Jacob, P. III. Slower metabolism and reduced intake of nicotine from cigarette smoking in Chinese-Americans. J. Natl. Cancer Inst. 94, 108-115 (2002).
    • (2002) J. Natl. Cancer Inst , vol.94 , pp. 108-115
    • Benowitz, N.L.1    Perez-Stable, E.J.2    Herrera, B.3    Jacob III, P.4
  • 23
    • 7744235961 scopus 로고    scopus 로고
    • Nicotine dependence and psychiatric disorders in the United States: Results from the national epidemiologic survey on alcohol and related conditions
    • Grant, B.F., Hasin, D.S., Chou, S.P., Stinson, F.S. & Dawson, D.A. Nicotine dependence and psychiatric disorders in the United States: results from the national epidemiologic survey on alcohol and related conditions. Arch. Gen. Psychiatry 61, 1107-1115 (2004).
    • (2004) Arch. Gen. Psychiatry , vol.61 , pp. 1107-1115
    • Grant, B.F.1    Hasin, D.S.2    Chou, S.P.3    Stinson, F.S.4    Dawson, D.A.5
  • 24
    • 33846616762 scopus 로고    scopus 로고
    • Monoamine oxidase and tobacco dependence
    • Lewis, A., Miller, J.H. & Lea, R.A. Monoamine oxidase and tobacco dependence. Neurotoxicology 28, 182-195 (2007).
    • (2007) Neurotoxicology , vol.28 , pp. 182-195
    • Lewis, A.1    Miller, J.H.2    Lea, R.A.3
  • 25
    • 10344238546 scopus 로고    scopus 로고
    • Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers
    • Fujieda, M. et al. Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers. Carcinogenesis 25, 2451-2458 (2004).
    • (2004) Carcinogenesis , vol.25 , pp. 2451-2458
    • Fujieda, M.1
  • 27
    • 34147195806 scopus 로고    scopus 로고
    • Overview of the pharmacogenomics of cigarette smoking
    • Ho, M.K. & Tyndale, R.F. Overview of the pharmacogenomics of cigarette smoking. Pharmacogenomics J. 7, 81-98 (2007).
    • (2007) Pharmacogenomics J , vol.7 , pp. 81-98
    • Ho, M.K.1    Tyndale, R.F.2
  • 28
    • 33846536406 scopus 로고    scopus 로고
    • Novel genes identified in a high-density genome wide association study for nicotine dependence
    • Bierut, L.J. et al. Novel genes identified in a high-density genome wide association study for nicotine dependence. Hum. Mol. Genet. 16, 24-35 (2007).
    • (2007) Hum. Mol. Genet , vol.16 , pp. 24-35
    • Bierut, L.J.1
  • 29
    • 33846510020 scopus 로고    scopus 로고
    • Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs
    • Saccone, S.F. et al. Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum. Mol. Genet. 16, 36-49 (2007).
    • (2007) Hum. Mol. Genet , vol.16 , pp. 36-49
    • Saccone, S.F.1
  • 30
    • 34247327670 scopus 로고    scopus 로고
    • Molecular genetics of nicotine dependence and abstinence: Whole genome association using 520,000 SNPs
    • Uhl, G.R., Liu, Q.R., Drgon, T., Johnson, C., Walther, D. & Rose, J.E. Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs. BMC Genet. 8, 10 (2007).
    • (2007) BMC Genet , vol.8 , pp. 10
    • Uhl, G.R.1    Liu, Q.R.2    Drgon, T.3    Johnson, C.4    Walther, D.5    Rose, J.E.6
  • 33
    • 85136430854 scopus 로고    scopus 로고
    • A clinical practice guideline for treating tobacco use and dependence: A US Public Health Service report. The Tobacco Use and Dependence Clinical Practice Guideline Panel, Staff, and Consortium Representatives. JAMA 283, 3244-3254 (2000).
    • A clinical practice guideline for treating tobacco use and dependence: A US Public Health Service report. The Tobacco Use and Dependence Clinical Practice Guideline Panel, Staff, and Consortium Representatives. JAMA 283, 3244-3254 (2000).
  • 34
    • 34347344890 scopus 로고    scopus 로고
    • Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation
    • Rollema, H., Coe, J.W., Chambers, L.K., Hurst, R.S., Stahl, S.M. & Williams, K.E. Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation. Trends Pharmacol. Sci. 28, 316-325 (2007).
    • (2007) Trends Pharmacol. Sci , vol.28 , pp. 316-325
    • Rollema, H.1    Coe, J.W.2    Chambers, L.K.3    Hurst, R.S.4    Stahl, S.M.5    Williams, K.E.6
  • 35
    • 33847047118 scopus 로고    scopus 로고
    • Non-nicotinic therapies for smoking cessation
    • Siu, E.C. & Tyndale, R.F. Non-nicotinic therapies for smoking cessation. Annu. Rev. Pharmacol. Toxicol. 47, 541-564 (2007).
    • (2007) Annu. Rev. Pharmacol. Toxicol , vol.47 , pp. 541-564
    • Siu, E.C.1    Tyndale, R.F.2
  • 36
    • 1542298180 scopus 로고    scopus 로고
    • Individualizing nicotine replacement therapy for the treatment of tobacco dependence: A randomized trial
    • Lerman, C. et al. Individualizing nicotine replacement therapy for the treatment of tobacco dependence: a randomized trial. Ann. Intern. Med. 140, 426-433 (2004).
    • (2004) Ann. Intern. Med , vol.140 , pp. 426-433
    • Lerman, C.1
  • 37
    • 33847708868 scopus 로고    scopus 로고
    • CYP2B6 genotype alters abstinence rates in a bupropion smoking cessation trial
    • Lee, A.M. et al. CYP2B6 genotype alters abstinence rates in a bupropion smoking cessation trial. Biol. Psychiatry 62, 635-641 (2007).
    • (2007) Biol. Psychiatry , vol.62 , pp. 635-641
    • Lee, A.M.1
  • 38
    • 33744519035 scopus 로고    scopus 로고
    • Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation
    • Lerman, C. et al. Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation. Clin. Pharmacol. Ther. 79, 600-608 (2006).
    • (2006) Clin. Pharmacol. Ther , vol.79 , pp. 600-608
    • Lerman, C.1
  • 39
    • 40949114996 scopus 로고    scopus 로고
    • Patterson, F. et al. Toward personalized therapy for tobacco dependence: use of the nicotine metabolite ratio 2007. Clin. Pharmacol. Ther., this issue.
    • Patterson, F. et al. Toward personalized therapy for tobacco dependence: use of the nicotine metabolite ratio 2007. Clin. Pharmacol. Ther., this issue.
  • 40
    • 34250222462 scopus 로고    scopus 로고
    • Oral use of Swedish moist snuff (snus) and risk for cancer of the mouth, lung, and pancreas in male construction workers: A retrospective cohort study
    • Luo, J. et al. Oral use of Swedish moist snuff (snus) and risk for cancer of the mouth, lung, and pancreas in male construction workers: a retrospective cohort study. Lancet 369, 2015-2020 (2007).
    • (2007) Lancet , vol.369 , pp. 2015-2020
    • Luo, J.1
  • 42
    • 33847608658 scopus 로고    scopus 로고
    • Tobacco-related disease mortality among men who switched from cigarettes to spit tobacco
    • Henley, S.J. et al. Tobacco-related disease mortality among men who switched from cigarettes to spit tobacco. Tob. Control 16, 22-28 (2007).
    • (2007) Tob. Control , vol.16 , pp. 22-28
    • Henley, S.J.1
  • 43
    • 28844477948 scopus 로고    scopus 로고
    • Smoking reduction treatment with 4-mg nicotine gum: A double-blind, randomized, placebo-controlled study
    • Batra, A., Klingler, K., Landfeldt, B., Friederich, H.M., Westin, A. & Danielsson, T. Smoking reduction treatment with 4-mg nicotine gum: a double-blind, randomized, placebo-controlled study. Clin. Pharmacol. Ther. 78, 689-696 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.78 , pp. 689-696
    • Batra, A.1    Klingler, K.2    Landfeldt, B.3    Friederich, H.M.4    Westin, A.5    Danielsson, T.6
  • 45
    • 1242314859 scopus 로고    scopus 로고
    • Nicotine and angiogenesis: A new paradigm for tobacco-related diseases
    • Cooke, J.P. & Bitterman, H. Nicotine and angiogenesis: a new paradigm for tobacco-related diseases. Ann. Med. 36, 33-40 (2004).
    • (2004) Ann. Med , vol.36 , pp. 33-40
    • Cooke, J.P.1    Bitterman, H.2
  • 47
    • 0028232207 scopus 로고
    • Establishing a nicotine threshold for addiction
    • Benowitz, N.L. & Henningfield, J.E. Establishing a nicotine threshold for addiction. N. Engl. J. Med. 331, 123-125 (1994).
    • (1994) N. Engl. J. Med , vol.331 , pp. 123-125
    • Benowitz, N.L.1    Henningfield, J.E.2
  • 49
    • 20444389783 scopus 로고    scopus 로고
    • Carcinogen exposure during short-term switching from regular to "light" cigarettes
    • Benowitz, N.L. et al. Carcinogen exposure during short-term switching from regular to "light" cigarettes. Cancer Epidemiol. Biomarkers Prev. 14, 1376-1383 (2005).
    • (2005) Cancer Epidemiol. Biomarkers Prev , vol.14 , pp. 1376-1383
    • Benowitz, N.L.1
  • 50
    • 38849169707 scopus 로고    scopus 로고
    • Benowitz, N.L., Hall, S.M., Stewart, S., Wilson, M., Dempsey, D. & Jacob, P. III Nicotine and carcinogen exposure with smoking of progressively reduced nicotine content cigarette. Cancer Epidemiol. Biomarkers Prev. 16, 2479-2485 (2007).
    • Benowitz, N.L., Hall, S.M., Stewart, S., Wilson, M., Dempsey, D. & Jacob, P. III Nicotine and carcinogen exposure with smoking of progressively reduced nicotine content cigarette. Cancer Epidemiol. Biomarkers Prev. 16, 2479-2485 (2007).
  • 51
    • 7944222898 scopus 로고    scopus 로고
    • The AMA proposal to mandate nicotine reduction in cigarettes: A simulation of the population health impacts
    • Tengs, T.O., Ahmad, S., Savage, J.M., Moore, R. & Gage, E. The AMA proposal to mandate nicotine reduction in cigarettes: a simulation of the population health impacts. Prev. Med. 40, 170-180 (2005).
    • (2005) Prev. Med , vol.40 , pp. 170-180
    • Tengs, T.O.1    Ahmad, S.2    Savage, J.M.3    Moore, R.4    Gage, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.