Reduced ciliary polycystin-2 in induced pluripotent stem cells from polycystic kidney disease patients with PKD1 mutations

Journal of the American Society of Nephrology

Volumn 24, Issue 10, 2013, Pages 1571-1586

  Freedman, Benjamin S ^a   Lam, Albert Q ^a,b   Sundsbak, Jamie L ^c   Iatrino, Rossella ^a,d   Su, Xuefeng ^a   Koon, Sarah J ^c   Wu, Maoqing ^a   Daheron, Laurence ^b   Harris, Peter C ^c   Zhou, Jing ^a,b   Bonventre, Joseph V ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

^c MAYO CLINIC   (United States)

^d UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; FIBROCYSTIN; HISTONE H3; POLYCYSTIN 1; POLYCYSTIN 2; CELL SURFACE RECEPTOR; PKHD1 PROTEIN, HUMAN; POLYCYSTIC KIDNEY DISEASE 1 PROTEIN; POLYCYSTIC KIDNEY DISEASE 2 PROTEIN; POLYCYSTIN;

ADULT; APOPTOSIS; ARTICLE; AUTOSOMAL DOMINANT DISORDER; AUTOSOMAL RECESSIVE DISORDER; BILE DUCT CYST; CASE REPORT; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; EUKARYOTIC FLAGELLUM; FAMILY HISTORY; FEMALE; FIBROBLAST; GENE MUTATION; GENE SEQUENCE; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HYDRONEPHROSIS; KIDNEY POLYCYSTIC DISEASE; LIVER CYST; LIVER DEVELOPMENT; MALE; MISSENSE MUTATION; NEWBORN; NONSENSE MUTATION; OLIGOHYDRAMNIOS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; CASE CONTROL STUDY; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY;

ADULT; CASE-CONTROL STUDIES; CELL LINE; FEMALE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INFANT, NEWBORN; MALE; MIDDLE AGED; POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT; POLYCYSTIC KIDNEY, AUTOSOMAL RECESSIVE; RECEPTORS, CELL SURFACE; TRPP CATION CHANNELS;

EID: 84885041970     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2012111089     Document Type: Article

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