Differentiation of human pluripotent stem cells into nephron progenitor cells in a serum and feeder free system

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Kang, Minyong ^a   Han, Yong Mahn ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; TRANSCRIPTION FACTOR PAX2; WT1 PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CITED1 GENE; CONTROLLED STUDY; EYA1 GENE; GDNF GENE; GENE; GENE EXPRESSION; GLOMERULUS; HOXD11 GENE; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY TUBULE EPITHELIUM; MESODERM; NEPHRON PROGENITOR CELL; OSR1 GENE; PAX2 GENE; PLURIPOTENT STEM CELL; PODOCYTE; SALL1 GENE; SIX2 GENE; STEM CELL; STEM CELL CULTURE; WT1 GENE; CELL LINE; CULTURE TECHNIQUE; CYTOLOGY; EMBRYONIC STEM CELL; EPITHELIUM CELL; KIDNEY TUBULE; NEPHRON; PRIMITIVE STREAK;

CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE; EMBRYONIC STEM CELLS; EPITHELIAL CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; KIDNEY TUBULES; MESODERM; NEPHRONS; PLURIPOTENT STEM CELLS; PODOCYTES; PRIMITIVE STREAK; STEM CELLS;

EID: 84899635769     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094888     Document Type: Article

References (47)

1. Hopkins C, Li J, Rae F, Little MH (2009) Stem cell options for kidney disease. J Pathol 217: 265-281.
2. Brodie JC, Humes HD (2005) Stem cell approaches for the treatment of renal failure. Pharmacol Rev 57: 299-313. (Pubitemid 41196952)
3. Stenvinkel P (2010) Chronic kidney disease: a public health priority and harbinger of premature cardiovascular disease. J Intern Med 268: 456-467.
4. Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, et al. (2007) Prevalence of chronic kidney disease in the United States. JAMA 298: 2038-2047. (Pubitemid 350074801)
5. Keith DS, Nichols GA, Gullion CM, Brown JB, Smith DH (2004) Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization. Arch Intern Med 164: 659-663. (Pubitemid 38392981)
6. Grassmann A, Gioberge S, Moeller S, Brown G (2005) ESRD patients in 2004: global overview of patient numbers, treatment modalities and associated trends. Nephrol Dial Transplant 20: 2587-2593. (Pubitemid 41672250)
7. Benigni A, Morigi M, Remuzzi G (2010) Kidney regeneration. Lancet 375: 1310-1317.
8. Yokoo T, Kawamura T, Kobayashi E (2008) Kidney organogenesis and regeneration: a new era in the treatment of chronic renal failure? Clin Exp Nephrol 12: 326-331.
9. Yokoo T, Fukui A, Matsumoto K, Okabe M (2008) Stem cells and kidney organogenesis. Front Biosci 13: 2814-2832. (Pubitemid 351606107)
10. Harari-Steinberg O, Pleniceanu O, Dekel B (2011) Selecting the optimal cell for kidney regeneration: fetal, adult or reprogrammed stem cells. Organogenesis 7: 123-134.
11. Yokote S, Yokoo T (2013) Organogenesis for kidney regeneration. Curr Opin Organ Transplant 18: 186-190.
12. Davies JA (2002) Morphogenesis of the metanephric kidney. ScientificWorld-Journal 2: 1937-1950.
13. Faa G, Gerosa C, Fanni D, Monga G, Zaffanello M, et al. (2012) Morphogenesis and molecular mechanisms involved in human kidney development. Journal of Cellular Physiology 227: 1257-1268.
14. Little MH, McMahon AP (2012) Mammalian kidney development: principles, progress, and projections. Cold Spring Harb Perspect Biol 4.
15. Dressler GR (2006) The cellular basis of kidney development. Annu Rev Cell Dev Biol 22: 509-529.
16. Michos O (2009) Kidney development: from ureteric bud formation to branching morphogenesis. Curr Opin Genet Dev 19: 484-490.
17. Bussolati B, Bruno S, Grange C, Buttiglieri S, Deregibus MC, et al. (2005) Isolation of renal progenitor cells from adult human kidney. Am J Pathol 166: 545-555. (Pubitemid 40189050)
18. Sagrinati C, Netti GS, Mazzinghi B, Lazzeri E, Liotta F, et al. (2006) Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. J Am Soc Nephrol 17: 2443-2456. (Pubitemid 44300960)
19. Ronconi E, Sagrinati C, Angelotti ML, Lazzeri E, Mazzinghi B, et al. (2009) Regeneration of glomerular podocytes by human renal progenitors. J Am Soc Nephrol 20: 322-332.
20. Lindgren D, Bostrom AK, Nilsson K, Hansson J, Sjolund J, et al. (2011) Isolation and characterization of progenitor-like cells from human renal proximal tubules. Am J Pathol 178: 828-837.
21. Romagnani P, Lasagni L, Remuzzi G (2013) Renal progenitors: an evolutionary conserved strategy for kidney regeneration. Nat Rev Nephrol 9: 137-146.
22. Harari-Steinberg O, Metsuyanim S, Omer D, Gnatek Y, Gershon R, et al. (2013) Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease. EMBO Mol Med 5: 1556-1568.
23. Lazzeri E, Crescioli C, Ronconi E, Mazzinghi B, Sagrinati C, et al. (2007) Regenerative potential of embryonic renal multipotent progenitors in acute renal failure. J Am Soc Nephrol 18: 3128-3138. (Pubitemid 350223972)
24. Pleniceanu O, Harari-Steinberg O, Dekel B (2010) Concise review: Kidney stem/progenitor cells: differentiate, sort out, or reprogram? Stem Cells 28: 1649-1660.
25. Kim D, Dressler GR (2005) Nephrogenic factors promote differentiation of mouse embryonic stem cells into renal epithelia. J Am Soc Nephrol 16: 3527-3534. (Pubitemid 46211273)
26. Morizane R, Monkawa T, Itoh H (2009) Differentiation of murine embryonic stem and induced pluripotent stem cells to renal lineage in vitro. Biochem Biophys Res Commun 390: 1334-1339.
27. Bruce SJ, Rea RW, Steptoe AL, Busslinger M, Bertram JF, et al. (2007) In vitro differentiation of murine embryonic stem cells toward a renal lineage. Differentiation 75: 337-349. (Pubitemid 46802153)
28. Ren X, Zhang J, Gong X, Niu X, Zhang X, et al. (2010) Differentiation of murine embryonic stem cells toward renal lineages by conditioned medium from ureteric bud cells in vitro. Acta Biochim Biophys Sin (Shanghai) 42: 464-471.
29. Nishikawa M, Yanagawa N, Kojima N, Yuri S, Hauser PV, et al. (2012) Stepwise renal lineage differentiation of mouse embryonic stem cells tracing in vivo development. Biochem Biophys Res Commun 417: 897-902.
30. Batchelder CA, Lee CC, Matsell DG, Yoder MC, Tarantal AF (2009) Renal ontogeny in the rhesus monkey (Macaca mulatta) and directed differentiation of human embryonic stem cells towards kidney precursors. Differentiation 78: 45-56.
31. Narayanan K, Schumacher KM, Tasnim F, Kandasamy K, Schumacher A, et al. (2013) Human embryonic stem cells differentiate into functional renal proximal tubular-like cells. Kidney Int 83: 593-603.
32. Mae S, Shono A, Shiota F, Yasuno T, Kajiwara M, et al. (2013) Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat Commun 4: 1367.
33. Xia Y, Nivet E, Sancho-Martinez I, Gallegos T, Suzuki K, et al. (2013) Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells. Nat Cell Biol 15: 1507-1515.
34. Park SW, Jun Koh Y, Jeon J, Cho YH, Jang MJ, et al. (2010) Efficient differentiation of human pluripotent stem cells into functional CD34+ progenitor cells by combined modulation of the MEK/ERK and BMP4 signaling pathways. Blood 116: 5762-5772.
35. Paige SL, Osugi T, Afanasiev OK, Pabon L, Reinecke H, et al. (2010) Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells. PLoS One 5: e11134.
36. Yokote S, Yamanaka S, Yokoo T (2012) De novo kidney regeneration with stem cells. J Biomed Biotechnol 2012: 453519.
37. Reidy KJ, Rosenblum ND (2009) Cell and molecular biology of kidney development. Semin Nephrol 29: 321-337.
38. Dressler GR (1995) Transcription factors in renal development: the WT1 and Pax-2 story. Semin Nephrol 15: 263-271.
39. Sanyanusin P, Schimmenti LA, McNoe LA, Ward TA, Pierpont ME, et al. (1995) Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux. Nat Genet 9: 358-364.
40. Sanchez MP, Silos-Santiago I, Frisen J, He B, Lira SA, et al. (1996) Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382: 70-73. (Pubitemid 26243359)
41. Xu PX, Adams J, Peters H, Brown MC, Heaney S, et al. (1999) Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nat Genet 23: 113-117. (Pubitemid 29418800)
42. Susa K, Kita S, Iwamoto T, Yang SS, Lin SH, et al. (2012) Effect of heterozygous deletion of WNK1 on the WNK-OSR1/SPAK-NCC/NKCC1/ NKCC2 signal cascade in the kidney and blood vessels. Clin Exp Nephrol 16: 530-538.
43. Hsu HJ, Lin G, Chung BC (2004) Parallel early development of zebrafish interrenal glands and pronephros: differential control by wt1 and ff1b. Endocr Res 30: 803. (Pubitemid 40070171)
44. Kreidberg JA (2010) WT1 and kidney progenitor cells. Organogenesis 6: 61-70.
45. Dressler G (2002) Tubulogenesis in the developing mammalian kidney. Trends Cell Biol 12: 390-395. (Pubitemid 35015149)
46. Bollig F, Perner B, Besenbeck B, Kothe S, Ebert C, et al. (2009) A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros. Development 136: 2883-2892.
47. Bilic J, Izpisua Belmonte JC (2012) Concise review: Induced pluripotent stem cells versus embryonic stem cells: close enough or yet too far apart? Stem Cells 30: 33-41.