Trypsin, tryptase, and thrombin polarize macrophages towards a pro-fibrotic M2a phenotype

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  White, Michael J V ^a   Gomer, Richard H ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GALECTIN 3; PROTEINASE ACTIVATED RECEPTOR; THROMBIN; TRYPSIN; TRYPTASE; CARRIER PROTEIN; GLYCOPROTEIN; LGALS3BP PROTEIN, HUMAN; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; TUMOR ANTIGEN; TUMOR MARKER;

ARTICLE; CELL DIFFERENTIATION; CELL POLARITY; CELL POPULATION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; PHENOTYPE; PROTEIN EXPRESSION; SCAR FORMATION; COCULTURE; CYTOLOGY; DRUG EFFECTS; FIBROBLAST; METABOLISM; MONONUCLEAR CELL;

ANTIGENS, NEOPLASM; BIOMARKERS, TUMOR; CARRIER PROTEINS; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; FIBROBLASTS; GALECTIN 3; GLYCOPROTEINS; HUMANS; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MONOCYTES; PHENOTYPE; RECEPTOR, PAR-1; RECEPTOR, PAR-2; THROMBIN; TRYPSIN; TRYPTASES;

EID: 84947239094     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0138748     Document Type: Article

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