Trypsin Potentiates Human Fibrocyte Differentiation

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  White, Michael J V ^a   Glenn, Melissa ^a   Gomer, Richard H ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; CHYMOTRYPSIN; COLLAGEN; ENDOPROTEASE GLU C; HUMAN ALBUMIN; INSULIN; PEPSIN A; PROTEINASE; TRANSFERRIN; TRYPSIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL ADHESION; CELL COUNT; CELL DIFFERENTIATION; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; FIBROCYTE; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN DEGRADATION; WOUND HEALING;

ANIMALS; CATTLE; CELL DIFFERENTIATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FIBROBLASTS; HUMANS; MONOCYTES; SERUM ALBUMIN; SERUM ALBUMIN, BOVINE; TRYPSIN; WOUND HEALING;

EID: 84881350462     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070795     Document Type: Article

References (73)

1. Drew P, Posnett J, Rusling L, (2007) The cost of wound care for a local population in England. Int Wound J 4: 149-155.
2. Hurd T, Posnett J, (2009) Point prevalence of wounds in a sample of acute hospitals in Canada. Int Wound J 6: 287-293.
3. Vowden KR, Vowden P, (2009) The prevalence, management and outcome for acute wounds identified in a wound care survey within one English health care district. J Tissue Viability 18: 7-12.
4. Vowden KR, Vowden P, (2009) A survey of wound care provision within one English health care district. J Tissue Viability 18: 2-6.
5. Srinivasaiah N, Dugdall H, Barrett S, Drew PJ (2007) A point prevalence survey of wounds in north-east England. J Wound Care 16: 413-416, 418-419.
6. Sen CK, Gordillo GM, Roy S, Kirsner R, Lambert L, et al. (2009) Human skin wounds: a major and snowballing threat to public health and the economy. Wound Repair Regen 17: 763-771.
7. Guo S, Dipietro LA, (2010) Factors affecting wound healing. J Dent Res 89: 219-229.
8. Hamilton JA, (2008) Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol 8: 533-544.
9. Murray PJ, Wynn TA, (2011) Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol 11: 723-737.
10. Abe R, Donnelly SC, Peng T, Bucala R, Metz CN, (2001) Peripheral blood fibrocytes: differentiation pathway and migration to wound sites. J Immunol 166: 7556-7562.
11. Bucala R, Spiegel LA, Chesney J, Hogan M, Cerami A, (1994) Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol Med 1: 71-81.
12. Reilkoff RA, Bucala R, Herzog EL, (2011) Fibrocytes: emerging effector cells in chronic inflammation. Nat Rev Immunol 11: 427-435.
13. Moeller A, Gilpin SE, Ask K, Cox G, Cook D, et al. (2009) Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 179: 588-594.
14. Quan TE, Cowper SE, Bucala R, (2006) The role of circulating fibrocytes in fibrosis. Curr Rheumatol Rep 8: 145-150.
15. Bellini A, Mattoli S, (2007) The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses. Lab Invest 87: 858-870.
16. Naik-Mathuria B, Pilling D, Crawford JR, Gay AN, Smith CW, et al. (2008) Serum amyloid P inhibits dermal wound healing. Wound Repair Regen 16: 266-273.
17. Pilling D, Vakil V, Gomer RH, (2009) Improved serum-free culture conditions for the differentiation of human and murine fibrocytes. J Immunol Methods 351: 62-70.
18. Cox N, Pilling D, Gomer RH, (2012) NaCl Potentiates Human Fibrocyte Differentiation. PLoS One 7: e45674.
19. Maharjan AS, Pilling D, Gomer RH, (2011) High and low molecular weight hyaluronic acid differentially regulate human fibrocyte differentiation. PLoS One 6: e26078.
20. Pilling D, Buckley CD, Salmon M, Gomer RH, (2003) Inhibition of fibrocyte differentiation by serum amyloid P. J Immunol. 171: 5537-5546.
21. Shao DD, Suresh R, Vakil V, Gomer RH, Pilling D, (2008) Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation. J Leukoc Biol 83: 1323-1333.
22. Pilling D, Roife D, Wang M, Ronkainen SD, Crawford JR, et al. (2007) Reduction of bleomycin-induced pulmonary fibrosis by serum amyloid P. J Immunol. 179: 4035-4044.
23. Collins N, (2001) The difference between albumin and prealbumin. Adv Skin Wound Care 14: 235-236.
24. Iizaka S, Sanada H, Matsui Y, Furue M, Tachibana T, et al. (2011) Serum albumin level is a limited nutritional marker for predicting wound healing in patients with pressure ulcer: two multicenter prospective cohort studies. Clin Nutr 30: 738-745.
25. Anthony D, Rafter L, Reynolds T, Aljezawi M, (2011) An evaluation of serum albumin and the sub-scores of the Waterlow score in pressure ulcer risk assessment. J Tissue Viability 20: 89-99.
26. Williams DF, Stotts NA, Nelson K, (2000) Patients with existing pressure ulcers admitted to acute care. J Wound Ostomy Continence Nurs 27: 216-226.
27. James TJ, Hughes MA, Cherry GW, Taylor RP, (2000) Simple biochemical markers to assess chronic wounds. Wound Repair Regen 8: 264-269.
28. Rodriguez J, Gupta N, Smith RD, Pevzner PA, (2008) Does trypsin cut before proline? J Proteome Res 7: 300-305.
29. Appel W, (1986) Chymotrypsin: molecular and catalytic properties. Clin Biochem 19: 317-322.
30. Dunn BM (2001) Overview of pepsin-like aspartic peptidases. Curr Protoc Protein Sci Chapter 21: Unit 21 23.
31. Drapeau GR, (1976) Protease from Staphyloccus aureus. Methods Enzymol 45: 469-475.
32. Drapeau GR, (1977) Cleavage at glutamic acid with staphylococcal protease. Methods Enzymol 47: 189-191.
33. Elzer KL, Heitzman DA, Chernin MI, Novak JF, (2008) Differential effects of serine proteases on the migration of normal and tumor cells: implications for tumor microenvironment. Integr Cancer Ther 7: 282-294.
34. Hirahara F, Miyagi Y, Miyagi E, Yasumitsu H, Koshikawa N, et al. (1995) Trypsinogen expression in human ovarian carcinomas. Int J Cancer 63: 176-181.
35. Koivunen E, Saksela O, Itkonen O, Osman S, Huhtala ML, et al. (1991) Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen. Int J Cancer 47: 592-596.
36. Miyata S, Koshikawa N, Higashi S, Miyagi Y, Nagashima Y, et al. (1999) Expression of trypsin in human cancer cell lines and cancer tissues and its tight binding to soluble form of Alzheimer amyloid precursor protein in culture. J Biochem 125: 1067-1076.
37. Ohta T, Terada T, Nagakawa T, Tajima H, Itoh H, et al. (1994) Pancreatic trypsinogen and cathepsin B in human pancreatic carcinomas and associated metastatic lesions. Br J Cancer 69: 152-156.
38. Soreide K, Janssen EA, Korner H, Baak JP, (2006) Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis. J Pathol 209: 147-156.
39. Fields RC, Schoenecker JG, Hart JP, Hoffman MR, Pizzo SV, et al. (2003) Protease-activated receptor-2 signaling triggers dendritic cell development. Am J Pathol 162: 1817-1822.
40. Toth J, Siklodi E, Medveczky P, Gallatz K, Nemeth P, et al. (2007) Regional distribution of human trypsinogen 4 in human brain at mRNA and protein level. Neurochem Res 32: 1423-1433.
41. Wang Y, Luo W, Reiser G, (2008) Trypsin and trypsin-like proteases in the brain: proteolysis and cellular functions. Cell Mol Life Sci 65: 237-252.
42. Paju A, Stenman UH, (2006) Biochemistry and clinical role of trypsinogens and pancreatic secretory trypsin inhibitor. Crit Rev Clin Lab Sci 43: 103-142.
43. Cocks TM, Fong B, Chow JM, Anderson GP, Frauman AG, et al. (1999) A protective role for protease-activated receptors in the airways. Nature 398: 156-160.
44. Fujimoto D, Hirono Y, Goi T, Katayama K, Hirose K, et al. (2006) Expression of protease activated receptor-2 (PAR-2) in gastric cancer. J Surg Oncol 93: 139-144.
45. Vu TK, Hung DT, Wheaton VI, Coughlin SR, (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64: 1057-1068.
46. Hansen KK, Oikonomopoulou K, Li Y, Hollenberg MD, (2008) Proteinases, proteinase-activated receptors (PARs) and the pathophysiology of cancer and diseases of the cardiovascular, musculoskeletal, nervous and gastrointestinal systems. Naunyn Schmiedebergs Arch Pharmacol 377: 377-392.
47. Suen JY, Gardiner B, Grimmond S, Fairlie DP, (2010) Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cells. PLoS One 5: e13809.
48. Martin GJ (1961) Wound healing composition. United States Patent Office. United States: The National Drug Company.
49. Anigstein L (1959) Wound healing agent obtained from blood and method of preparation. United States Patent Office. United States.
50. Fortney DZ (1996) Compositions containing protease produced by vibrio and method of use in debridement and wound healing. United States Patent Office. United States: W.R. Grace and Company.
51. Pritchard DI (2011) Treatment of wounds. United States Patent Office. United States.
52. Cetrulo GI, (1953) Use of trypsin intravenously in a gunshot wound. J Am Med Assoc 152: 605-606.
53. Carson SN, Wiggins C, Overall K, Herbert J, (2003) Using a castor oil-balsam of Peru-trypsin ointment to assist in healing skin graft donor sites. Ostomy Wound Manage 49: 60-64.
54. Beitz JM (2005) Heparin-induced thrombocytopenia syndrome bullous lesions treated with trypsin-balsam of peru-castor oil ointment: a case study. Ostomy Wound Manage 51: 52-54, 56-58.
55. Russell TM, Herzog EL, Bucala R, (2012) Flow cytometric identification of fibrocytes in scleroderma lung disease. Methods Mol Biol 900: 327-346.
56. Pilling D, Tucker NM, Gomer RH, (2006) Aggregated IgG inhibits the differentiation of human fibrocytes. J Leukoc Biol 79: 1242-1251.
57. Rothmeier AS, Ruf W, (2012) Protease-activated receptor 2 signaling in inflammation. Semin Immunopathol 34: 133-149.
58. Hortin GL, Sviridov D, Anderson NL, (2008) High-abundance polypeptides of the human plasma proteome comprising the top 4 logs of polypeptide abundance. Clin Chem 54: 1608-1616.
59. Green NM, (1953) Competition among trypsin inhibitors. J Biol Chem 205: 535-551.
60. Bundy HF, Mehl JW, (1958) Trypsin inhibitors of human serum. I. Standardization, mechanism of reaction, and normal values. J Clin Invest 37: 947-955.
61. Bundy HF, Mehl JW, (1959) Trypsin inhibitors of human serum. II. Isolation of the alpha 1-inhibitor and its partial characterization. J Biol Chem 234: 1124-1128.
62. Moore BB, Murray L, Das A, Wilke CA, Herrygers AB, et al. (2006) The role of CCL12 in the recruitment of fibrocytes and lung fibrosis. Am J Respir Cell Mol Biol 35: 175-181.
63. MacNaughton WK, (2005) Epithelial effects of proteinase-activated receptors in the gastrointestinal tract. Mem Inst Oswaldo Cruz 100Suppl 1: 211-215.
64. Mall M, Gonska T, Thomas J, Hirtz S, Schreiber R, et al. (2002) Activation of ion secretion via proteinase-activated receptor-2 in human colon. Am J Physiol Gastrointest Liver Physiol 282: G200-210.
65. Ramachandran R, Hollenberg MD, (2008) Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more. Br J Pharmacol 153Suppl 1: S263-282.
66. Vergnolle N, (2004) Modulation of visceral pain and inflammation by protease-activated receptors. Br J Pharmacol 141: 1264-1274.
67. Coulson-Thomas VJ, Coulson-Thomas YM, Gesteira TF, de Paula CA, Mader AM, et al. (2011) Colorectal cancer desmoplastic reaction up-regulates collagen synthesis and restricts cancer cell invasion. Cell Tissue Res 346: 223-236.
68. Shao ZM, Nguyen M, Barsky SH, (2000) Human breast carcinoma desmoplasia is PDGF initiated. Oncogene 19: 4337-4345.
69. Walker RA, (2001) The complexities of breast cancer desmoplasia. Breast Cancer Res 3: 143-145.
70. Li W, Danilenko DM, Bunting S, Ganesan R, Sa S, et al. (2009) The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyperproliferative epidermis of psoriasis and regenerating wounds. J Biol Chem 284: 218-228.
71. Borgono CA, Michael IP, Diamandis EP, (2004) Human tissue kallikreins: physiologic roles and applications in cancer. Mol Cancer Res 2: 257-280.
72. Yamamoto H, Iku S, Adachi Y, Imsumran A, Taniguchi H, et al. (2003) Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer. J Pathol 199: 176-184.
73. Nakamura K, Hongo A, Kodama J, Abarzua F, Nasu Y, et al. (2009) Expression of matriptase and clinical outcome of human endometrial cancer. Anticancer Res 29: 1685-1690.