Altered expression of mast cell chymase and tryptase and of c-Kit in human cutaneous scar tissue

Journal of Investigative Dermatology

Volumn 114, Issue 1, 2000, Pages 51-55

  Hermes, Barbara ^a   Feldmann Böddeker, Ingrid ^c   Welker, Pia ^c   Algermissen, Bernd ^a   Steckelings, Muscha U ^c   Grabbe, Jürgen ^c   Henz, Beate M ^b  

^a VIVANTES KLINIKUM NEUKÖLLN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c NONE

Author keywords

c Kit; Chymase; Mast cells; Tryptase; Wound healing

Indexed keywords

AVIDIN; CHYMASE; STEM CELL FACTOR; TRYPTASE;

ARTICLE; CELL MATURATION; CELL SUBPOPULATION; ENZYME ACTIVITY; ENZYME HISTOCHEMISTRY; FIBROBLAST; HUMAN; HUMAN TISSUE; MAST CELL; MEDIATOR RELEASE; MELANOSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SCAR; WOUND HEALING;

EID: 0034075603     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.00837.x     Document Type: Article

References (47)

1. Algermissen B, Bauer F, Schadendorf D, Kropp JD, Czarnetzki BM: Analysis of mast cell subpopulations (MCT, MCTC) in cutaneous inflammation using novel enzyme-histochemical staining techniques. Exp Dermatol 3:290-297, 1994
2. Artuc M, Hermes B, Steckelings UM, Grützkau A, Henz BM: Mast cells and their mediators in cutaneous wound healing - active participants or innocent bystanders? Exp Dermatol 8:1-16, 1999
3. Atkins FM, Clark RAF: Mast cells and fibrosis. Arch Dermatol 123:191-193, 1987
4. Bergstresser PR, Tigelaar RE, Tharp MD: Conjugated avidin identifies cutaneous rodent and human mast cells. J Invest Dermatol 83:214-218, 1984
5. Blair RJ, Meng H, Marchese MJ, Ren S, Schwartz LB, Tonnesen MG: Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor. J Clin Invest 99:2691-2700, 1997
6. Claman HN: Mast cells and fibrosis. The relevance to scleroderma. Rheum Dis Clin N Am 16:141-151, 1990
7. Czarnetzki BM, Grabbe J, Kolde G, Krüger-Krasagakes S, Zuberbier T: Mast cells in the cytokine network - the what, where from and what for. Exp Dermatol 4:221-226, 1995
8. Dippel E, Haas N, Grabbe J, Schadendorf D, Hamann K, Czarnetzki BM: Expression of the c-kit receptor in hypomelanosis: a comparative study between piebaldism, nevus depigmentosus and vitiligo. Br J Dermatol 132:182-189, 1995
9. Grabbe J, Haas N, Hamann K, Kolde G, Hakimi J, Czarnetzki BM: Demonstration of the high affinity IgE receptor on human Langerhans cells in normal and diseased skin. Br J Dermatol 129:120-123, 1993
10. Grabbe J, Welker P, Rosenbach T, et al: Release of stem cell factor (SCF) from human keratinocytes (HaCaT) is increased in differentiating versus proliferating cells. J Invest Dermatol 107:219-224, 1996
11. Gruber BL, Kew RR, Jelaska A, Marchese MJ, Garlick J, Ren S, Schwartz LB, Korn JH: Human mast cells activate fibroblasts: tryptase is a fibrogenic factor stimulating collagen messenger ribonucleic acid synthesis and fibroblast chemotaxis. J Immunol 158:2310-2317, 1997
12. Haas N, Hamann K, Grabbe J, Algermissen B, Czametzki BM: Phenotypic evaluation of skin lesions in urticaria pigmentosa and mastocytosis. Arch Dermatol Res 286:380-385, 1994
13. Hamann K, Grabbe J, Welker P, Haas N, Algermissen B, Czarnetzki BM: Phenotypic evaluation of cultured human mast and basophilic cells and of normal human skin mast cells. Arch Dermatol Res 286:380-385, 1994
14. Harvima IT, Schlechter NM, Harvima RJ, Fräki JE: Human skin tryptase: purification, partial characterisation and comparison with human lung tryptase. Biochim Biophys Acta 957:71-80, 1988
15. Harvima IT, Naukkarinen A, Harvima RJ, Aalto ML, Horsmanheimo M: Quantitative enzyme-histochemical analysis of tryptase-and chymase-containing mast cells in psoriatic skin. Arch Dermatol Res 282:428-433, 1990
16. Harvima IT, Horsmanheimo L, Naukkarinen A, Horsmanheimo M: Mast cell proteinases and cytokines in skin inflammation. Arch Dermatol Res 287:61-67, 1994
17. Hebda PA, Collins MA, Tharp MD: Mast cell and myofibroblast in wound healing. Dermatol Clin 11:685-696, 1993
18. Irani AA, Schechter NM, Craig SS, DeBlois G, Schwartz LB: Two types of human mast cells that have distinct neutral protease compositions. Proc Natl Acad Sci USA 83:4464-4468, 1986
19. Irani AMA, Schwartz LB: Human mast cell heterogeneity. Clin Exp Allergy 19:143-155, 1989
20. Irani AMA, Gruber BL, Kaufman LD, Kahaleh MB, Schwartz LB: Mast cell changes in scleroderma. Arthritis Rheumatism 35:933-939, 1992
21. Kirshenbaum AS, Worobec AS, Davis TA, Goff JP, Semere T, Metcalfe DD: Inhibition of human mast cell growth and differentation by interferon gamma-1b. Exp Hematol 26:245-251, 1998
22. Lassam V, Bickford S: Loss of c-kit expression in cultured melanoma cells. Oncogene 7:51-56, 1992
23. Lerner NB, Nocka KH, Cole SR, Qui F, Strife A, Ashman LK, Besmer P: Monoclonal antibody YB5.B8 identifies the human c-kit protein product. Blood 77:1876-1883, 1991
24. Levi-Schaffer F, Rubinchik E: Activated mast cells are fibrogenic for 3T3 fibroblasts. J Invest Dermatol 104:999-1003, 1995
25. Li L, Macpherson JJ, Adelstein S, Bunn CL, Atkinson K, Phadke K, Krilis SA: Conditioned media from a cell strain derived from a patient with mastocytosis induces preferential development of cells that possess high affinity IgE receptors and the granule protease phenotype of mature cutaneous mast cells. J Biol Chem 270:2258-2263, 1995
26. Longley BJ Jr, Morganroth GS, Tyrrell L, Ding TG, Anderson DM, Williams DE, Halaban R: Altered metabolism of mast-cell growth factor (c-kit ligand) in cutaneous mastocytosis. N Engl J Med 328:1302-1307, 1993
27. Longley BJ, Tyrrell L, Ma Y, et al: Chymase cleavage of stem cell factor yields a bioactive, soluble product. Proc Natl Acad Sci USA 94:9017-9021, 1997
28. Maurer D, Fiebiger E, Reininger B, et al: Expression of functional high affinity immunoglobulin E receptors (FcεRI) on monocytes of atopic individuals. J Exp Med 179:745-750, 1994
29. Mayrhofer G, Gadd SJ, Spargo LDJ, Ashman LK: Specificity of a mouse monoclonal antibody raised against acute myeloid leukemia cells for mast cells in human mucosal and connective tissues. Immunol Cell Biol 65:241-250, 1987
30. Metcalfe DD, Baram D, Mekori YA: Mast cells. Physiol Rev 77:1033-1079, 1997
31. Natali PG, Nicotra MR, Winkler AB, Cavaliere R, Bigotti A, Ullrich A: Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor. Int J Cancer 52:197-201, 1992
32. Persinger MA, LePage P, Simard JP: Mast cell numbers in incisional wounds in rat skin as a function of distance, time and treatment. Br J Dermatol 108:179-187, 1987
33. Ratajczak MZ, Luger SM, De Riel K, Abrahm J, Calabretta B, Gewirtz AM: Role of the KIT protooncogene in normal and malignant human hematopoiesis. Proc Natl Acad Sci USA 89:1710-1714, 1992
34. Sambrooke J, Fritsch EF, Maniatis T. Analysis of RNA. In: Ford N, Nolan C, Ferguson M eds. Molecular Cloning, 2nd edn. Cold Spring Harbour: Laboratory Press, 1989, p. 7.43
35. Schadendorf D, Tiedemann K-H, Haas N, Czarnetzki BM: Detection of human papilloma viruses in paraffin-embedded condylomata accuminata. Comparison of immunhistochemistry, in situ hybridization, and polymerase chain reaction. J Invest Dermatol 97:549-554, 1991
36. Schwartz LB, Kepley C: Development of markers for human basophils and mast cells. J Allergy Clin Immunol 94:1231-1240, 1994
37. Schwartz LB, Irani AM, Roller K, Castells MC, Schechter NM: Quantitation of histamine, tryptase and chymase in dispersed human T and TC mast cells. J Immunol 138:2611-2615, 1987
38. Seibold JR, Giorno RC, Claman HN: Dermal mast cell degranulation in systemic sclerosis. Arthritis Rheumatism 33:1702-1709, 1990
39. Shimuzu Y, Ashman LK, Du Z, Schwartz LB: Intemalization of kit together with stem cell factor on human fetal liver-derived mast cells. J Immunol 156:3443-3449, 1996
40. Sillaber CH, Bevec D, Ashman LK, et al: II-4 regulates c-kit gene product expression in human mast and myeloid cell progenitors. J Immunol 147:4224-4228, 1991
41. Vijayasaradhi S, Houghton AN: Purification and autoantigenic 75 kDa human melanosomal glycoprotein. Int J Cancer 47:298-303, 1991
42. Wang B, Rieger A, Kilgus O, Maurer D, Födinger D, Kinet J-P, Stingl G: Epidermal Langerhans cells from normal human skin bind monomeric IgE via FcεRI. J Exp Med 175:1353-1365, 1992
43. Weber S, Krüger-Krasagakes S, Grabbe J, Zuberbier T, Czarnetzki BM: Mast cells. Int J Dermatol 34:1-10, 1995
44. Weiss RR, Whitacker-Menezes D, Longley J, Bender J, Murphy GF: Human dermal endothelial cells express membrane-associated mast cell growth factor. J Invest Dermatol 104:101-106, 1995
45. Welker P, Grabbe J, Möller A, Dippel E, Ashmann LK, Czarnetzki BM: Comparative cytokine release from human monocytes, monocyte-derived immature mast cells and a human mast cell line (HMC1). J Invest Dermatol 103:504-508, 1994
46. Welker P, Grabbe J, Grützkau A, Henz BM: Effects of NGF and other fibroblast-derived growth factors on immature human mast cells (HMC-1). Immunology 94:310-317, 1998
47. Wichmann BE: The mast cell count during the process of wound healing: an experimental investigation on rats. Acta Pathol Microbiol Scand 108:1-14, 1955