DZNep inhibits the proliferation of colon cancer HCT116 cells by inducing senescence and apoptosis

Acta Pharmaceutica Sinica B

Volumn 5, Issue 3, 2015, Pages 188-193

  Sha, Mingquan ^a   Mao, Genxiang ^b   Wang, Guofu ^b   Chen, Yufeng ^c   Wu, Xiaojian ^c   Wang, Zhen ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^b ZHEJIANG HOSPITAL   (China)

^c THE SIXTH AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

Author keywords

Anti cancer mechanisms; DZNep; EZH2; Human colon cancer HCT116 cells

Indexed keywords

3 DEAZANEPLANOCIN A; CYCLIN DEPENDENT KINASE 1; EMBRYONIC ECTODERM DEVELOPMENT PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN P21; PROTEIN P27; RETINOBLASTOMA PROTEIN; SUZ12 PROTEIN; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL AGING; CELL CYCLE REGULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; G1 PHASE CELL CYCLE CHECKPOINT; HCT116 CELL LINE; HUMAN; HUMAN CELL; PROTEIN EXPRESSION;

EID: 84947202101     PISSN: 22113835     EISSN: 22113843     Source Type: Journal    
DOI: 10.1016/j.apsb.2015.01.011     Document Type: Article

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