메뉴 건너뛰기




Volumn 14, Issue 21, 2008, Pages 6790-6796

Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; DOXORUBICIN; ENHANCER OF ZESTE HOMOLOGUE 2; GEMCITABINE; HISTONE METHYLTRANSFERASE; UNCLASSIFIED DRUG; CDKN1B PROTEIN, HUMAN; DNA BINDING PROTEIN; EZH2 PROTEIN, HUMAN; PROTEIN METHYLTRANSFERASE; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR;

EID: 58149214373     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-08-1013     Document Type: Article
Times cited : (165)

References (31)
  • 2
    • 27544505676 scopus 로고    scopus 로고
    • Chromatin modifier enzymes, the histone code and cancer
    • Santos-Rosa H, Caldas C. Chromatin modifier enzymes, the histone code and cancer. Eur J Cancer 2005;41:2381-402.
    • (2005) Eur J Cancer , vol.41 , pp. 2381-2402
    • Santos-Rosa, H.1    Caldas, C.2
  • 3
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in Polycomb-group silencing
    • Cao R, Wang L, Wang H, et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 2002;298:1039-43.
    • (2002) Science , vol.298 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3
  • 4
    • 32844459336 scopus 로고    scopus 로고
    • The Polycomb group protein EZH2 directly controls DNA methylation
    • Viré E, Brenner C, Deplus R, et al. The Polycomb group protein EZH2 directly controls DNA methylation. Nature 2006;439:871-4.
    • (2006) Nature , vol.439 , pp. 871-874
    • Viré, E.1    Brenner, C.2    Deplus, R.3
  • 5
    • 0034070298 scopus 로고    scopus 로고
    • The human EZH2 gene: Genomic organisation and revised mapping in 7q35 within the critical region for malignant myeloid disorders
    • Cardoso C, Mignon C, Hetet G, Grandchamps B, Fontes M, Colleaux L. The human EZH2 gene: genomic organisation and revised mapping in 7q35 within the critical region for malignant myeloid disorders. Eur J Hum Genet 2000;8:174-80.
    • (2000) Eur J Hum Genet , vol.8 , pp. 174-180
    • Cardoso, C.1    Mignon, C.2    Hetet, G.3    Grandchamps, B.4    Fontes, M.5    Colleaux, L.6
  • 6
    • 0035050744 scopus 로고    scopus 로고
    • The Polycomb group protein EZH2 is up-regulated in proliferating, cultured human mantle cell lymphoma
    • Visser HP, Gunster MJ, Kluin-Nelemans HC, et al. The Polycomb group protein EZH2 is up-regulated in proliferating, cultured human mantle cell lymphoma. Br J Haematol 2001;112:950-8.
    • (2001) Br J Haematol , vol.112 , pp. 950-958
    • Visser, H.P.1    Gunster, M.J.2    Kluin-Nelemans, H.C.3
  • 7
    • 33745228778 scopus 로고    scopus 로고
    • Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells
    • Abbosh PH, Montgomery JS, Starkey JA, et al. Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells. Cancer Res 2006;66:5582-91.
    • (2006) Cancer Res , vol.66 , pp. 5582-5591
    • Abbosh, P.H.1    Montgomery, J.S.2    Starkey, J.A.3
  • 8
    • 41349104897 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 down-regulates E-cadherin by mediating histone H3 methylation in gastric cancer cells
    • Fujii S, Ochiai A. Enhancer of zeste homolog 2 down-regulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. Cancer Sci 2008;99:738-46.
    • (2008) Cancer Sci , vol.99 , pp. 738-746
    • Fujii, S.1    Ochiai, A.2
  • 9
    • 18644382388 scopus 로고    scopus 로고
    • The polycomb group protein EZH2 is involved in progression of prostate cancer
    • Varambally S, Dhanasekaran SM, Zhou M, et al. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 2002;419:624-9.
    • (2002) Nature , vol.419 , pp. 624-629
    • Varambally, S.1    Dhanasekaran, S.M.2    Zhou, M.3
  • 10
    • 0141816752 scopus 로고    scopus 로고
    • EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
    • Kleer CG, Cao Q, Varambally S, et al. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc Natl Acad Sci U S A 2003;100:11606-11.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11606-11611
    • Kleer, C.G.1    Cao, Q.2    Varambally, S.3
  • 11
    • 1342342913 scopus 로고    scopus 로고
    • Differential regulation of TCR-mediated gene transcription by Vav family members
    • Zakaria S, Gomes TS, Savoy DN, et al. Differential regulation of TCR-mediated gene transcription by Vav family members. J Exp Med 2004;199:429-34.
    • (2004) J Exp Med , vol.199 , pp. 429-434
    • Zakaria, S.1    Gomes, T.S.2    Savoy, D.N.3
  • 12
    • 3543078617 scopus 로고    scopus 로고
    • Associations among β-TrCP, an E3 ubiquitin ligase receptor, β-catenin, and NF-κB in colorectal cancer
    • Ougolkov A, Zhang B, Yamashita K, et al. Associations among β-TrCP, an E3 ubiquitin ligase receptor, β-catenin, and NF-κB in colorectal cancer. J Natl Cancer Inst 2004;96:1161-70.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1161-1170
    • Ougolkov, A.1    Zhang, B.2    Yamashita, K.3
  • 13
    • 16844374033 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β participates in nuclear factor-κB- mediated gene transcription and cell survival in pancreatic cancer cells
    • Ougolkov AV, Fernandez-Zapico ME, Savoy DN, Urrutia RA, and Billadeau DD. Glycogen synthase kinase-3β participates in nuclear factor-κB- mediated gene transcription and cell survival in pancreatic cancer cells. Cancer Res 2005;65:2076-81.
    • (2005) Cancer Res , vol.65 , pp. 2076-2081
    • Ougolkov, A.V.1    Fernandez-Zapico, M.E.2    Savoy, D.N.3    Urrutia, R.A.4    Billadeau, D.D.5
  • 14
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, and Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983;11:1475-89.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 15
    • 0031048236 scopus 로고    scopus 로고
    • Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
    • Loda M, Cukor B, Tam S, et al. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med 1997;3:231-4.
    • (1997) Nat Med , vol.3 , pp. 231-234
    • Loda, M.1    Cukor, B.2    Tam, S.3
  • 16
    • 0029024015 scopus 로고
    • Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
    • Pagano M, Tam SW, Theodoras AM, et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 1995;269:682-5.
    • (1995) Science , vol.269 , pp. 682-685
    • Pagano, M.1    Tam, S.W.2    Theodoras, A.M.3
  • 17
    • 0032751323 scopus 로고    scopus 로고
    • Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation
    • van der Vlag J, Otte AP. Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation. Nat Genet 1999;23:474-8.
    • (1999) Nat Genet , vol.23 , pp. 474-478
    • van der Vlag, J.1    Otte, A.P.2
  • 18
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • Sparmann A, van Lohuizen M. Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 2006;6:846-56.
    • (2006) Nat Rev Cancer , vol.6 , pp. 846-856
    • Sparmann, A.1    van Lohuizen, M.2
  • 20
    • 0013482014 scopus 로고    scopus 로고
    • Adenocarcinoma of the pancreas: Overview of workup and management
    • Casper ES, Kelsen DP. Adenocarcinoma of the pancreas: overview of workup and management. Adv Oncol 1996;11:17-22.
    • (1996) Adv Oncol , vol.11 , pp. 17-22
    • Casper, E.S.1    Kelsen, D.P.2
  • 21
    • 33744519651 scopus 로고    scopus 로고
    • Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer
    • Matsukawa Y, Semba S, Kato H, Ito A, Yanagihara K, Yokozaki H. Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer. Cancer Sci 2006;97:484-91.
    • (2006) Cancer Sci , vol.97 , pp. 484-491
    • Matsukawa, Y.1    Semba, S.2    Kato, H.3    Ito, A.4    Yanagihara, K.5    Yokozaki, H.6
  • 22
    • 29344445843 scopus 로고    scopus 로고
    • Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder
    • Raman JD, Mongan NP, Tickoo SK, Boorjian SA, Scherr DS, Gudas LJ. Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder. Clin Cancer Res 2005;11:8570-6.
    • (2005) Clin Cancer Res , vol.11 , pp. 8570-8576
    • Raman, J.D.1    Mongan, N.P.2    Tickoo, S.K.3    Boorjian, S.A.4    Scherr, D.S.5    Gudas, L.J.6
  • 23
    • 9144226103 scopus 로고    scopus 로고
    • Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene
    • Raaphorst FM, Meijer CJ, Fieret E, et al. Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene. Neoplasia 2003;5:481-8.
    • (2003) Neoplasia , vol.5 , pp. 481-488
    • Raaphorst, F.M.1    Meijer, C.J.2    Fieret, E.3
  • 25
    • 41149150219 scopus 로고    scopus 로고
    • The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
    • Chu IM, Hengst L, Slingerland JM. The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 2008;8:253-67.
    • (2008) Nat Rev Cancer , vol.8 , pp. 253-267
    • Chu, I.M.1    Hengst, L.2    Slingerland, J.M.3
  • 26
    • 0033798404 scopus 로고    scopus 로고
    • An immunohistochemical analysis of p27 expression in human pancreatic carcinomas
    • Hu YX, Watanabe H, Li P, et al. An immunohistochemical analysis of p27 expression in human pancreatic carcinomas. Pancreas 2000;21:226-30.
    • (2000) Pancreas , vol.21 , pp. 226-230
    • Hu, Y.X.1    Watanabe, H.2    Li, P.3
  • 27
    • 50249175130 scopus 로고    scopus 로고
    • Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers
    • Wei Y, Xia W, Zhang Z, et al. Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers. Mol Carcinog 2008;47:701-6.
    • (2008) Mol Carcinog , vol.47 , pp. 701-706
    • Wei, Y.1    Xia, W.2    Zhang, Z.3
  • 28
    • 0034182738 scopus 로고    scopus 로고
    • Increased expression levels of cyclin-dependent kinase inhibitor p27 correlate with good responses to platinum-based chemotherapy in non-small cell lung cancer
    • Oshita F, Kameda Y, Nishio K, et al. Increased expression levels of cyclin-dependent kinase inhibitor p27 correlate with good responses to platinum-based chemotherapy in non-small cell lung cancer. Oncol Rep 2000;7:491-5.
    • (2000) Oncol Rep , vol.7 , pp. 491-495
    • Oshita, F.1    Kameda, Y.2    Nishio, K.3
  • 29
    • 0034351879 scopus 로고    scopus 로고
    • p27Kip1 expression is associated with clinical outcome in advanced epithelial ovarian cancer: Multivariate analysis
    • Masciullo V, Ferrandina G, Pucci B, et al. p27Kip1 expression is associated with clinical outcome in advanced epithelial ovarian cancer: multivariate analysis. Clin Cancer Res 2000;6:4816-22.
    • (2000) Clin Cancer Res , vol.6 , pp. 4816-4822
    • Masciullo, V.1    Ferrandina, G.2    Pucci, B.3
  • 30
    • 19544381048 scopus 로고    scopus 로고
    • Growth of LNCaP cells in monoculture and coculture with osteoblasts and response to tNOX inhibitors
    • Axanova L, Morré DJ, Morré DM. Growth of LNCaP cells in monoculture and coculture with osteoblasts and response to tNOX inhibitors. Cancer Lett 2005;225:35.
    • (2005) Cancer Lett , vol.225 , pp. 35
    • Axanova, L.1    Morré, D.J.2    Morré, D.M.3
  • 31
    • 0027986676 scopus 로고
    • Epidermal growth factor-mediated apoptosis of MDA-MB-468 human breast cancer cells
    • Armstrong DK, Kaufmann SH, Ottaviano YL, et al. Epidermal growth factor-mediated apoptosis of MDA-MB-468 human breast cancer cells. Cancer Res 1994;54:5280-3.
    • (1994) Cancer Res , vol.54 , pp. 5280-5283
    • Armstrong, D.K.1    Kaufmann, S.H.2    Ottaviano, Y.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.