Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells

Experimental Cell Research

Volumn 319, Issue 10, 2013, Pages 1463-1470

  Benoit, Yannick D ^a,c   Witherspoon, Mavee S ^a   Laursen, Kristian B ^a   Guezguez, Amel ^b   Beauséjour, Marco ^b   Beaulieu, Jean Francois ^b   Lipkin, Steven M ^a   Gudas, Lorraine J ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITÉ DE SHERBROOKE   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Apoptosis; Colon cancer; DZNep; Polycomb; PTEN; Stem cells

Indexed keywords

3 DEAZANEPLANOCIN A; HISTONE METHYLTRANSFERASE; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN; SUZ12 PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER STEM CELL; CELL ISOLATION; CELL SURVIVAL; COLON CANCER STEM CELL; COLORECTAL TUMOR; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; PHOSPHORYLATION; PRIORITY JOURNAL;

EID: 84877927474     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.04.006     Document Type: Article

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