-
1
-
-
68949094312
-
Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy
-
Kopetz, S.; Chang, G.J.; Overman, M.J.; Eng, C.; Sargent, D.J.; Larson, D.W.; Grothey, A.; Vauthey, J.N.; Nagorney, D.M.; McWilliams, R.R. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J. Clin. Oncol. 2009, 27, 3677-3683.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 3677-3683
-
-
Kopetz, S.1
Chang, G.J.2
Overman, M.J.3
Eng, C.4
Sargent, D.J.5
Larson, D.W.6
Grothey, A.7
Vauthey, J.N.8
Nagorney, D.M.9
McWilliams, R.R.10
-
2
-
-
35348992639
-
The genetics of hereditary colon cancer
-
Rustgi, A.K. The genetics of hereditary colon cancer. Genes Dev. 2007, 21, 2525-2538.
-
(2007)
Genes Dev.
, vol.21
, pp. 2525-2538
-
-
Rustgi, A.K.1
-
3
-
-
54249154703
-
Dietary induction of colonic tumors in a mouse model of sporadic colon cancer
-
Yang, K.; Kurihara, N.; Fan, K.; Newmark, H.; Rigas, B.; Bancroft, L.; Corner, G.; Livote, E.; Lesser, M.; Edelmann, W.; et al. Dietary induction of colonic tumors in a mouse model of sporadic colon cancer. Cancer Res. 2008, 68, 7803-7810.
-
(2008)
Cancer Res.
, vol.68
, pp. 7803-7810
-
-
Yang, K.1
Kurihara, N.2
Fan, K.3
Newmark, H.4
Rigas, B.5
Bancroft, L.6
Corner, G.7
Livote, E.8
Lesser, M.9
Edelmann, W.10
-
4
-
-
77951635438
-
Inflammation and colon cancer
-
Terzic, J.; Grivennikov, S.; Karin, E.; Karin, M. Inflammation and colon cancer. Gastroenterology 2010, 138, 2101-2114. e5.
-
(2010)
Gastroenterology
, vol.138
-
-
Terzic, J.1
Grivennikov, S.2
Karin, E.3
Karin, M.4
-
5
-
-
0038587747
-
The two faces of IKK and NF-kappaB inhibition: Prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion
-
Chen, L.W.; Egan, L.; Li, Z.W.; Greten, F.R.; Kagnoff, M.F.; Karin, M. The two faces of IKK and NF-kappaB inhibition: Prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat. Med. 2003, 9, 575-581.
-
(2003)
Nat. Med.
, vol.9
, pp. 575-581
-
-
Chen, L.W.1
Egan, L.2
Li, Z.W.3
Greten, F.R.4
Kagnoff, M.F.5
Karin, M.6
-
6
-
-
33745025705
-
IFNgamma-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice
-
Hanada, T.; Kobayashi, T.; Chinen, T.; Saeki, K.; Takaki, H.; Koga, K.; Minoda, Y.; Sanada, T.; Yoshioka, T.; Mimata, H.; et al. IFNgamma-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice. J. Exp. Med. 2006, 203, 1391-1397.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1391-1397
-
-
Hanada, T.1
Kobayashi, T.2
Chinen, T.3
Saeki, K.4
Takaki, H.5
Koga, K.6
Minoda, Y.7
Sanada, T.8
Yoshioka, T.9
Mimata, H.10
-
7
-
-
67650330166
-
Carcinogenesis in IBD: Potential targets for the prevention of colorectal cancer
-
Feagins, L.A.; Souza, R.F.; Spechler, S.J. Carcinogenesis in IBD: Potential targets for the prevention of colorectal cancer. Nat. Rev. Gastroenterol. Hepatol. 2009, 6, 297-305.
-
(2009)
Nat. Rev. Gastroenterol. Hepatol.
, vol.6
, pp. 297-305
-
-
Feagins, L.A.1
Souza, R.F.2
Spechler, S.J.3
-
8
-
-
0031972522
-
Cancer cells exhibit a mutator phenotype
-
Loeb, L.A. Cancer cells exhibit a mutator phenotype. Adv. Cancer Res. 1998, 72, 25-56.
-
(1998)
Adv. Cancer Res.
, vol.72
, pp. 25-56
-
-
Loeb, L.A.1
-
9
-
-
0030852491
-
Foulds' dangerous idea revisited: The multistep development of tumors 40 years later
-
Klein, G. Foulds' dangerous idea revisited: The multistep development of tumors 40 years later. Adv. Cancer Res. 1998, 72, 1-23.
-
(1998)
Adv. Cancer Res.
, vol.72
, pp. 1-23
-
-
Klein, G.1
-
10
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E.R.; Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell 1990, 61, 759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
11
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler, K.W.; Vogelstein, B. Lessons from hereditary colorectal cancer. Cell 1996, 87, 159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
12
-
-
30644459835
-
Serrated pathway and APC (conventional)-type colorectal polyps: Molecular-morphologic correlations, genetic pathways, and implications for classification
-
Goldstein, N.S. Serrated pathway and APC (conventional)-type colorectal polyps: Molecular-morphologic correlations, genetic pathways, and implications for classification. Am. J. Clin. Pathol. 2006, 125, 146-153.
-
(2006)
Am. J. Clin. Pathol.
, vol.125
, pp. 146-153
-
-
Goldstein, N.S.1
-
13
-
-
0034626769
-
The age of cancer
-
DePinho, R.A. The age of cancer. Nature 2000, 408, 248-254.
-
(2000)
Nature
, vol.408
, pp. 248-254
-
-
DePinho, R.A.1
-
14
-
-
66149095468
-
Serrated polyps and colorectal cancer: New pathway to malignancy
-
Noffsinger, A.E. Serrated polyps and colorectal cancer: New pathway to malignancy. Annu. Rev. Pathol. 2009, 4, 343-364.
-
(2009)
Annu. Rev. Pathol.
, vol.4
, pp. 343-364
-
-
Noffsinger, A.E.1
-
15
-
-
33645526144
-
Cancer statistics, 2006
-
Jemal, A.; Siegel, R.; Ward, E.; Murray, T.; Xu, J.; Smigal, C.; Thun, M.J. Cancer statistics, 2006. CA Cancer J. Clin. 2006, 56, 106-130.
-
(2006)
CA Cancer J. Clin.
, vol.56
, pp. 106-130
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Smigal, C.6
Thun, M.J.7
-
16
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
Toyota, M.; Ahuja, N.; Ohe-Toyota, M.; Herman, J.G.; Baylin, S.B.; Issa, J.P. CpG island methylator phenotype in colorectal cancer. Proc. Natl. Acad. Sci. USA 1999, 96, 8681-8686.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8681-8686
-
-
Toyota, M.1
Ahuja, N.2
Ohe-Toyota, M.3
Herman, J.G.4
Baylin, S.B.5
Issa, J.P.6
-
17
-
-
33644853907
-
The colorectal microRNAome
-
Cummins, J.M.; He, Y.; Leary, R.J.; Pagliarini, R.; Diaz, L.A., Jr.; Sjoblom, T.; Barad, O.; Bentwich, Z.; Szafranska, A.E.; Labourier, E.; et al. The colorectal microRNAome. Proc. Natl. Acad. Sci. USA 2006, 103, 3687-3692.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 3687-3692
-
-
Cummins, J.M.1
He, Y.2
Leary, R.J.3
Pagliarini, R.4
Diaz Jr., L.A.5
Sjoblom, T.6
Barad, O.7
Bentwich, Z.8
Szafranska, A.E.9
Labourier, E.10
-
18
-
-
79954435158
-
Colorectal cancer epigenetics: Complex simplicity
-
Van Engeland, M.; Derks, S.; Smits, K.M.; Meijer, G.A.; Herman, J.G. Colorectal cancer epigenetics: Complex simplicity. J. Clin. Oncol. 2011, 29, 1382-1391.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 1382-1391
-
-
van Engeland, M.1
Derks, S.2
Smits, K.M.3
Meijer, G.A.4
Herman, J.G.5
-
19
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjoblom, T.; Jones, S.; Wood, L.D.; Parsons, D.W.; Lin, J.; Barber, T.D.; Mandelker, D.; Leary, R.J.; Ptak, J.; Silliman, N.; et al. The consensus coding sequences of human breast and colorectal cancers. Science 2006, 314, 268-274.
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
Parsons, D.W.4
Lin, J.5
Barber, T.D.6
Mandelker, D.7
Leary, R.J.8
Ptak, J.9
Silliman, N.10
-
20
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
Wood, L.D.; Parsons, D.W.; Jones, S.; Lin, J.; Sjoblom, T.; Leary, R.J.; Shen, D.; Boca, S.M.; Barber, T.; Ptak, J.; et al. The genomic landscapes of human breast and colorectal cancers. Science 2007, 318, 1108-1113.
-
(2007)
Science
, vol.318
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
Lin, J.4
Sjoblom, T.5
Leary, R.J.6
Shen, D.7
Boca, S.M.8
Barber, T.9
Ptak, J.10
-
21
-
-
36649005377
-
Molecular heterogeneity of colorectal cancer: Implications for cancer control
-
Jass, J.R. Molecular heterogeneity of colorectal cancer: Implications for cancer control. Surg. Oncol. 2007, 16, S7-S9.
-
(2007)
Surg. Oncol.
, vol.16
-
-
Jass, J.R.1
-
22
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein, B.; Fearon, E.R.; Hamilton, S.R.; Kern, S.E.; Preisinger, A.C.; Leppert, M.; Nakamura, Y.; White, R.; Smits, A.M.; Bos, J.L. Genetic alterations during colorectal-tumor development. N. Engl. J. Med. 1988, 319, 525-532.
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
Kern, S.E.4
Preisinger, A.C.5
Leppert, M.6
Nakamura, Y.7
White, R.8
Smits, A.M.9
Bos, J.L.10
-
23
-
-
57049114832
-
The genetics of the p53 pathway, apoptosis and cancer therapy
-
Vazquez, A.; Bond, E.E.; Levine, A.J.; Bond, G.L. The genetics of the p53 pathway, apoptosis and cancer therapy. Nat. Rev. Drug Discov. 2008, 7, 979-987.
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 979-987
-
-
Vazquez, A.1
Bond, E.E.2
Levine, A.J.3
Bond, G.L.4
-
24
-
-
0034785348
-
TGF-beta signaling in tumor suppression and cancer progression
-
Derynck, R.; Akhurst, R.J.; Balmain, A. TGF-beta signaling in tumor suppression and cancer progression. Nat. Genet. 2001, 29, 117-129.
-
(2001)
Nat. Genet.
, vol.29
, pp. 117-129
-
-
Derynck, R.1
Akhurst, R.J.2
Balmain, A.3
-
25
-
-
16044369574
-
MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
-
Eppert, K.; Scherer, S.W.; Ozcelik, H.; Pirone, R.; Hoodless, P.; Kim, H.; Tsui, L.C.; Bapat, B.; Gallinger, S.; Andrulis, I.L.; et al. MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 1996, 86, 543-552.
-
(1996)
Cell
, vol.86
, pp. 543-552
-
-
Eppert, K.1
Scherer, S.W.2
Ozcelik, H.3
Pirone, R.4
Hoodless, P.5
Kim, H.6
Tsui, L.C.7
Bapat, B.8
Gallinger, S.9
Andrulis, I.L.10
-
26
-
-
0032489508
-
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
-
Takaku, K.; Oshima, M.; Miyoshi, H.; Matsui, M.; Seldin, M.F.; Taketo, M.M. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 1998, 92, 645-656.
-
(1998)
Cell
, vol.92
, pp. 645-656
-
-
Takaku, K.1
Oshima, M.2
Miyoshi, H.3
Matsui, M.4
Seldin, M.F.5
Taketo, M.M.6
-
27
-
-
79751489596
-
Molecular genetics of colorectal cancer
-
Fearon, E.R. Molecular genetics of colorectal cancer. Annu. Rev. Pathol. 2011, 6, 479-507.
-
(2011)
Annu. Rev. Pathol.
, vol.6
, pp. 479-507
-
-
Fearon, E.R.1
-
28
-
-
24144449572
-
Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer
-
Samowitz, W.S.; Albertsen, H.; Herrick, J.; Levin, T.R.; Sweeney, C.; Murtaugh, M.A.; Wolff, R.K.; Slattery, M.L. Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer. Gastroenterology 2005, 129, 837-845.
-
(2005)
Gastroenterology
, vol.129
, pp. 837-845
-
-
Samowitz, W.S.1
Albertsen, H.2
Herrick, J.3
Levin, T.R.4
Sweeney, C.5
Murtaugh, M.A.6
Wolff, R.K.7
Slattery, M.L.8
-
29
-
-
56649084987
-
Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample
-
Nosho, K.; Irahara, N.; Shima, K.; Kure, S.; Kirkner, G.J.; Schernhammer, E.S.; Hazra, A.; Hunter, D.J.; Quackenbush, J.; Spiegelman, D.; et al. Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample. PLoS One 2008, 3, e3698.
-
(2008)
PLoS One
, vol.3
-
-
Nosho, K.1
Irahara, N.2
Shima, K.3
Kure, S.4
Kirkner, G.J.5
Schernhammer, E.S.6
Hazra, A.7
Hunter, D.J.8
Quackenbush, J.9
Spiegelman, D.10
-
30
-
-
33645672858
-
Microsatellite instability in colorectal cancer
-
Soreide, K.; Janssen, E.A.; Soiland, H.; Korner, H.; Baak, J.P. Microsatellite instability in colorectal cancer. Br. J. Surg. 2006, 93, 395-406.
-
(2006)
Br. J. Surg.
, vol.93
, pp. 395-406
-
-
Soreide, K.1
Janssen, E.A.2
Soiland, H.3
Korner, H.4
Baak, J.P.5
-
31
-
-
0036789184
-
Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability
-
Hermsen, M.; Postma, C.; Baak, J.; Weiss, M.; Rapallo, A.; Sciutto, A.; Roemen, G.; Arends, J.W.; Williams, R.; Giaretti, W.; et al. Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability. Gastroenterology 2002, 123, 1109-1119.
-
(2002)
Gastroenterology
, vol.123
, pp. 1109-1119
-
-
Hermsen, M.1
Postma, C.2
Baak, J.3
Weiss, M.4
Rapallo, A.5
Sciutto, A.6
Roemen, G.7
Arends, J.W.8
Williams, R.9
Giaretti, W.10
-
32
-
-
3142691130
-
Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas
-
Douglas, E.J.; Fiegler, H.; Rowan, A.; Halford, S.; Bicknell, D.C.; Bodmer, W.; Tomlinson, I.P.; Carter, N.P. Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas. Cancer Res. 2004, 64, 4817-4825.
-
(2004)
Cancer Res.
, vol.64
, pp. 4817-4825
-
-
Douglas, E.J.1
Fiegler, H.2
Rowan, A.3
Halford, S.4
Bicknell, D.C.5
Bodmer, W.6
Tomlinson, I.P.7
Carter, N.P.8
-
33
-
-
36348970735
-
Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types
-
Martin, E.S.; Tonon, G.; Sinha, R.; Xiao, Y.; Feng, B.; Kimmelman, A.C.; Protopopov, A.; Ivanova, E.; Brennan, C.; Montgomery, K.; et al. Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types. Cancer Res. 2007, 67, 10736-10743.
-
(2007)
Cancer Res.
, vol.67
, pp. 10736-10743
-
-
Martin, E.S.1
Tonon, G.2
Sinha, R.3
Xiao, Y.4
Feng, B.5
Kimmelman, A.C.6
Protopopov, A.7
Ivanova, E.8
Brennan, C.9
Montgomery, K.10
-
34
-
-
84860599697
-
Colorectal cancer: A tale of two sides or a continuum?
-
Yamauchi, M.; Lochhead, P.; Morikawa, T.; Huttenhower, C.; Chan, A.T.; Giovannucci, E.; Fuchs, C.; Ogino, S. Colorectal cancer: A tale of two sides or a continuum? Gut 2012, 61, 794-797.
-
(2012)
Gut
, vol.61
, pp. 794-797
-
-
Yamauchi, M.1
Lochhead, P.2
Morikawa, T.3
Huttenhower, C.4
Chan, A.T.5
Giovannucci, E.6
Fuchs, C.7
Ogino, S.8
-
35
-
-
72449176846
-
Molecular origins of cancer: Molecular basis of colorectal cancer
-
Markowitz, S.D.; Bertagnolli, M.M. Molecular origins of cancer: Molecular basis of colorectal cancer. N. Engl. J. Med. 2009, 361, 2449-2460.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2449-2460
-
-
Markowitz, S.D.1
Bertagnolli, M.M.2
-
36
-
-
78651241644
-
Colorectal cancer molecular biology moves into clinical practice
-
Pritchard, C.C.; Grady, W.M. Colorectal cancer molecular biology moves into clinical practice. Gut 2011, 60, 116-129.
-
(2011)
Gut
, vol.60
, pp. 116-129
-
-
Pritchard, C.C.1
Grady, W.M.2
-
37
-
-
77449130761
-
Microsatellite instability in colorectal cancer
-
Boland, C.R.; Goel, A. Microsatellite instability in colorectal cancer. Gastroenterology 2010, 138, 2073-2087. e3.
-
(2010)
Gastroenterology
, vol.138
-
-
Boland, C.R.1
Goel, A.2
-
38
-
-
33745541234
-
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
-
Weisenberger, D.J.; Siegmund, K.D.; Campan, M.; Young, J.; Long, T.I.; Faasse, M.A.; Kang, G.H.; Widschwendter, M.; Weener, D.; Buchanan, D.; et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat. Genet. 2006, 38, 787-793.
-
(2006)
Nat. Genet.
, vol.38
, pp. 787-793
-
-
Weisenberger, D.J.1
Siegmund, K.D.2
Campan, M.3
Young, J.4
Long, T.I.5
Faasse, M.A.6
Kang, G.H.7
Widschwendter, M.8
Weener, D.9
Buchanan, D.10
-
39
-
-
78650186379
-
Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer
-
Tanaka, N.; Huttenhower, C.; Nosho, K.; Baba, Y.; Shima, K.; Quackenbush, J.; Haigis, K.M.; Giovannucci, E.; Fuchs, C.S.; Ogino, S. Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer. Am. J. Pathol. 2010, 177, 2731-2740.
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 2731-2740
-
-
Tanaka, N.1
Huttenhower, C.2
Nosho, K.3
Baba, Y.4
Shima, K.5
Quackenbush, J.6
Haigis, K.M.7
Giovannucci, E.8
Fuchs, C.S.9
Ogino, S.10
-
40
-
-
80052926952
-
Comprehensive analysis of CpG island methylator phenotype (CIMP)-high,-low, and-negative colorectal cancers based on protein marker expression and molecular features
-
Zlobec, I.; Bihl, M.; Foerster, A.; Rufle, A.; Lugli, A. Comprehensive analysis of CpG island methylator phenotype (CIMP)-high,-low, and-negative colorectal cancers based on protein marker expression and molecular features. J. Pathol. 2011, 225, 336-343.
-
(2011)
J. Pathol.
, vol.225
, pp. 336-343
-
-
Zlobec, I.1
Bihl, M.2
Foerster, A.3
Rufle, A.4
Lugli, A.5
-
41
-
-
84856512550
-
Predictive and prognostic roles of BRAF mutation in stage III colon cancer: Results from intergroup trial CALGB 89803
-
Ogino, S.; Shima, K.; Meyerhardt, J.A.; McCleary, N.J.; Ng, K.; Hollis, D.; Saltz, L.B.; Mayer, R.J.; Schaefer, P.; Whittom, R.; et al. Predictive and prognostic roles of BRAF mutation in stage III colon cancer: Results from intergroup trial CALGB 89803. Clin. Cancer Res. 2012, 18, 890-900.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 890-900
-
-
Ogino, S.1
Shima, K.2
Meyerhardt, J.A.3
McCleary, N.J.4
Ng, K.5
Hollis, D.6
Saltz, L.B.7
Mayer, R.J.8
Schaefer, P.9
Whittom, R.10
-
42
-
-
41349091456
-
Map of differential transcript expression in the normal human large intestine
-
LaPointe, L.C.; Dunne, R.; Brown, G.S.; Worthley, D.L.; Molloy, P.L.; Wattchow, D.; Young, G.P. Map of differential transcript expression in the normal human large intestine. Physiol. Genomics 2008, 33, 50-64.
-
(2008)
Physiol. Genomics
, vol.33
, pp. 50-64
-
-
LaPointe, L.C.1
Dunne, R.2
Brown, G.S.3
Worthley, D.L.4
Molloy, P.L.5
Wattchow, D.6
Young, G.P.7
-
43
-
-
77949953247
-
Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status
-
Campbell, P.T.; Jacobs, E.T.; Ulrich, C.M.; Figueiredo, J.C.; Poynter, J.N.; McLaughlin, J.R.; Haile, R.W.; Jacobs, E.J.; Newcomb, P.A.; Potter, J.D.; et al. Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status. J. Natl. Cancer Inst. 2010, 102, 391-400.
-
(2010)
J. Natl. Cancer Inst.
, vol.102
, pp. 391-400
-
-
Campbell, P.T.1
Jacobs, E.T.2
Ulrich, C.M.3
Figueiredo, J.C.4
Poynter, J.N.5
McLaughlin, J.R.6
Haile, R.W.7
Jacobs, E.J.8
Newcomb, P.A.9
Potter, J.D.10
-
44
-
-
0034669076
-
Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors
-
Slattery, M.L.; Curtin, K.; Anderson, K.; Ma, K.N.; Ballard, L.; Edwards, S.; Schaffer, D.; Potter, J.; Leppert, M.; Samowitz, W.S. Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors. J. Natl. Cancer Inst. 2000, 92, 1831-1836.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1831-1836
-
-
Slattery, M.L.1
Curtin, K.2
Anderson, K.3
Ma, K.N.4
Ballard, L.5
Edwards, S.6
Schaffer, D.7
Potter, J.8
Leppert, M.9
Samowitz, W.S.10
-
45
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D.; Weinberg, R.A. Hallmarks of cancer: The next generation. Cell 2011, 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
46
-
-
77954960188
-
Pilot study of sentinel-node-based adoptive immunotherapy in advanced colorectal cancer
-
Karlsson, M.; Marits, P.; Dahl, K.; Dagoo, T.; Enerback, S.; Thorn, M.; Winqvist, O. Pilot study of sentinel-node-based adoptive immunotherapy in advanced colorectal cancer. Ann. Surg. Oncol. 2010, 17, 1747-1757.
-
(2010)
Ann. Surg. Oncol.
, vol.17
, pp. 1747-1757
-
-
Karlsson, M.1
Marits, P.2
Dahl, K.3
Dagoo, T.4
Enerback, S.5
Thorn, M.6
Winqvist, O.7
-
47
-
-
84877136981
-
Lymphotoxin beta receptor mediates caspase-dependent tumor cell apoptosis in vitro and tumor suppression in vivo despite induction of NF-kappaB activation
-
PubMed ID:23349015
-
Hu, X.; Zimmerman, A.M.; Bardhan, K.; Yang, D.; Waller, J.L.; Liles, G.B.; Lee, J.R.; Pollock, R.; Lev, D.; Ware, C.F.; et al. Lymphotoxin beta receptor mediates caspase-dependent tumor cell apoptosis in vitro and tumor suppression in vivo despite induction of NF-kappaB activation. Carcinogenesis 2013, PubMed ID:23349015.
-
(2013)
Carcinogenesis
-
-
Hu, X.1
Zimmerman, A.M.2
Bardhan, K.3
Yang, D.4
Waller, J.L.5
Liles, G.B.6
Lee, J.R.7
Pollock, R.8
Lev, D.9
Ware, C.F.10
-
48
-
-
84864087098
-
NF-kappaB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression
-
Liu, F.; Bardhan, K.; Yang, D.; Thangaraju, M.; Ganapathy, V.; Waller, J.L.; Liles, G.B.; Lee, J.R.; Liu, K. NF-kappaB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression. J. Biol. Chem. 2012, 287, 25530-25540.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 25530-25540
-
-
Liu, F.1
Bardhan, K.2
Yang, D.3
Thangaraju, M.4
Ganapathy, V.5
Waller, J.L.6
Liles, G.B.7
Lee, J.R.8
Liu, K.9
-
49
-
-
84866381896
-
Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance
-
Zimmerman, M.A.; Rahman, N.T.; Yang, D.; Lahat, G.; Lazar, A.J.; Pollock, R.E.; Lev, D.; Liu, K. Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance. Cancer Res. 2012, 72, 4724-4732.
-
(2012)
Cancer Res.
, vol.72
, pp. 4724-4732
-
-
Zimmerman, M.A.1
Rahman, N.T.2
Yang, D.3
Lahat, G.4
Lazar, A.J.5
Pollock, R.E.6
Lev, D.7
Liu, K.8
-
50
-
-
84862508128
-
Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells
-
Zimmerman, M.A.; Singh, N.; Martin, P.M.; Thangaraju, M.; Ganapathy, V.; Waller, J.L.; Shi, H.; Robertson, K.D.; Munn, D.H.; Liu, K. Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. Am. J. Physiol. Gastrointest. Liver Physiol. 2012, 302, G1405-1415.
-
(2012)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.302
-
-
Zimmerman, M.A.1
Singh, N.2
Martin, P.M.3
Thangaraju, M.4
Ganapathy, V.5
Waller, J.L.6
Shi, H.7
Robertson, K.D.8
Munn, D.H.9
Liu, K.10
-
51
-
-
33646755569
-
Cancer immunosurveillance and immunoediting: The roles of immunity in suppressing tumor development and shaping tumor immunogenicity
-
Smyth, M.J.; Dunn, G.P.; Schreiber, R.D. Cancer immunosurveillance and immunoediting: The roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv. Immunol. 2006, 90, 1-50.
-
(2006)
Adv. Immunol.
, vol.90
, pp. 1-50
-
-
Smyth, M.J.1
Dunn, G.P.2
Schreiber, R.D.3
-
52
-
-
29144514645
-
Effector memory T cells, early metastasis, and survival in colorectal cancer
-
Pages, F.; Berger, A.; Camus, M.; Sanchez-Cabo, F.; Costes, A.; Molidor, R.; Mlecnik, B.; Kirilovsky, A.; Nilsson, M.; Damotte, D.; et al. Effector memory T cells, early metastasis, and survival in colorectal cancer. N. Engl. J. Med. 2005, 353, 2654-2666.
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 2654-2666
-
-
Pages, F.1
Berger, A.2
Camus, M.3
Sanchez-Cabo, F.4
Costes, A.5
Molidor, R.6
Mlecnik, B.7
Kirilovsky, A.8
Nilsson, M.9
Damotte, D.10
-
53
-
-
0030902366
-
The prognostic significance of intratumoral natural killer cells in patients with colorectal carcinoma
-
Coca, S.; Perez-Piqueras, J.; Martinez, D.; Colmenarejo, A.; Saez, M.A.; Vallejo, C.; Martos, J.A.; Moreno, M. The prognostic significance of intratumoral natural killer cells in patients with colorectal carcinoma. Cancer 1997, 79, 2320-2328.
-
(1997)
Cancer
, vol.79
, pp. 2320-2328
-
-
Coca, S.1
Perez-Piqueras, J.2
Martinez, D.3
Colmenarejo, A.4
Saez, M.A.5
Vallejo, C.6
Martos, J.A.7
Moreno, M.8
-
54
-
-
9144273838
-
+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: Possible association with suppression of micrometastasis
-
+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: Possible association with suppression of micrometastasis. Br. J. Cancer 2004, 91, 1711-1717.
-
(2004)
Br. J. Cancer
, vol.91
, pp. 1711-1717
-
-
Chiba, T.1
Ohtani, H.2
Mizoi, T.3
Naito, Y.4
Sato, E.5
Nagura, H.6
Ohuchi, A.7
Ohuchi, K.8
Shiiba, K.9
Kurokawa, Y.10
-
55
-
-
33749319703
-
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
-
Galon, J.; Costes, A.; Sanchez-Cabo, F.; Kirilovsky, A.; Mlecnik, B.; Lagorce-Pages, C.; Tosolini, M.; Camus, M.; Berger, A.; Wind, P.; et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006, 313, 1960-1964.
-
(2006)
Science
, vol.313
, pp. 1960-1964
-
-
Galon, J.1
Costes, A.2
Sanchez-Cabo, F.3
Kirilovsky, A.4
Mlecnik, B.5
Lagorce-Pages, C.6
Tosolini, M.7
Camus, M.8
Berger, A.9
Wind, P.10
-
57
-
-
58249089749
-
+ T regulatory cells show strong prognostic significance in colorectal cancer
-
+ T regulatory cells show strong prognostic significance in colorectal cancer. J. Clin. Oncol. 2009, 27, 186-192.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 186-192
-
-
Salama, P.1
Phillips, M.2
Grieu, F.3
Morris, M.4
Zeps, N.5
Joseph, D.6
Platell, C.7
Iacopetta, B.8
-
58
-
-
33749347023
-
Will Rogers revisited: Prospective observational study of survival of 3592 patients with colorectal cancer according to number of nodes examined by pathologists
-
George, S.; Primrose, J.; Talbot, R.; Smith, J.; Mullee, M.; Bailey, D.; du Boulay, C.; Jordan, H. Will Rogers revisited: Prospective observational study of survival of 3592 patients with colorectal cancer according to number of nodes examined by pathologists. Br. J. Cancer 2006, 95, 841-847.
-
(2006)
Br. J. Cancer
, vol.95
, pp. 841-847
-
-
George, S.1
Primrose, J.2
Talbot, R.3
Smith, J.4
Mullee, M.5
Bailey, D.6
du Boulay, C.7
Jordan, H.8
-
59
-
-
0036158699
-
Lymph node recoveries from 2427 pT3 colorectal resection specimens spanning 45 years: Recommendations for a minimum number of recovered lymph nodes based on predictive probabilities
-
Goldstein, N.S. Lymph node recoveries from 2427 pT3 colorectal resection specimens spanning 45 years: Recommendations for a minimum number of recovered lymph nodes based on predictive probabilities. Am. J. Surg. Pathol. 2002, 26, 179-189.
-
(2002)
Am. J. Surg. Pathol.
, vol.26
, pp. 179-189
-
-
Goldstein, N.S.1
-
60
-
-
0041885405
-
Colon cancer survival is associated with increasing number of lymph nodes analyzed: A secondary survey of intergroup trial INT-0089
-
Le Voyer, T.E.; Sigurdson, E.R.; Hanlon, A.L.; Mayer, R.J.; Macdonald, J.S.; Catalano, P.J.; Haller, D.G. Colon cancer survival is associated with increasing number of lymph nodes analyzed: A secondary survey of intergroup trial INT-0089. J. Clin. Oncol. 2003, 21, 2912-2919.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2912-2919
-
-
le Voyer, T.E.1
Sigurdson, E.R.2
Hanlon, A.L.3
Mayer, R.J.4
McDonald, J.S.5
Catalano, P.J.6
Haller, D.G.7
-
61
-
-
13744262529
-
Lymph node evaluation in colorectal cancer patients: A population-based study
-
Baxter, N.N.; Virnig, D.J.; Rothenberger, D.A.; Morris, A.M.; Jessurun, J.; Virnig, B.A. Lymph node evaluation in colorectal cancer patients: A population-based study. J. Natl. Cancer Inst. 2005, 97, 219-225.
-
(2005)
J. Natl. Cancer Inst.
, vol.97
, pp. 219-225
-
-
Baxter, N.N.1
Virnig, D.J.2
Rothenberger, D.A.3
Morris, A.M.4
Jessurun, J.5
Virnig, B.A.6
-
62
-
-
33646850390
-
Lymph node counts, rates of positive lymph nodes, and patient survival for colon cancer surgery in Ontario, Canada: A population-based study
-
Bui, L.; Rempel, E.; Reeson, D.; Simunovic, M. Lymph node counts, rates of positive lymph nodes, and patient survival for colon cancer surgery in Ontario, Canada: A population-based study. J. Surg. Oncol. 2006, 93, 439-445.
-
(2006)
J. Surg. Oncol.
, vol.93
, pp. 439-445
-
-
Bui, L.1
Rempel, E.2
Reeson, D.3
Simunovic, M.4
-
63
-
-
34047245618
-
Lymph node evaluation and survival after curative resection of colon cancer: Systematic review
-
Chang, G.J.; Rodriguez-Bigas, M.A.; Skibber, J.M.; Moyer, V.A. Lymph node evaluation and survival after curative resection of colon cancer: Systematic review. J. Natl. Cancer Inst. 2007, 99, 433-441.
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 433-441
-
-
Chang, G.J.1
Rodriguez-Bigas, M.A.2
Skibber, J.M.3
Moyer, V.A.4
-
64
-
-
70350225838
-
Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype
-
Ogino, S.; Nosho, K.; Irahara, N.; Meyerhardt, J.A.; Baba, Y.; Shima, K.; Glickman, J.N.; Ferrone, C.R.; Mino-Kenudson, M.; Tanaka, N.; et al. Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype. Clin. Cancer Res. 2009, 15, 6412-6420.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 6412-6420
-
-
Ogino, S.1
Nosho, K.2
Irahara, N.3
Meyerhardt, J.A.4
Baba, Y.5
Shima, K.6
Glickman, J.N.7
Ferrone, C.R.8
Mino-Kenudson, M.9
Tanaka, N.10
-
65
-
-
78349277576
-
Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: Cohort study and literature review
-
Nosho, K.; Baba, Y.; Tanaka, N.; Shima, K.; Hayashi, M.; Meyerhardt, J.A.; Giovannucci, E.; Dranoff, G.; Fuchs, C.S.; Ogino, S. Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: Cohort study and literature review. J. Pathol. 2010, 222, 350-366.
-
(2010)
J. Pathol.
, vol.222
, pp. 350-366
-
-
Nosho, K.1
Baba, Y.2
Tanaka, N.3
Shima, K.4
Hayashi, M.5
Meyerhardt, J.A.6
Giovannucci, E.7
Dranoff, G.8
Fuchs, C.S.9
Ogino, S.10
-
66
-
-
0035060624
-
Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status
-
Michael-Robinson, J.M.; Biemer-Huttmann, A.; Purdie, D.M.; Walsh, M.D.; Simms, L.A.; Biden, K.G.; Young, J.P.; Leggett, B.A.; Jass, J.R.; Radford-Smith, G.L. Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status. Gut 2001, 48, 360-366.
-
(2001)
Gut
, vol.48
, pp. 360-366
-
-
Michael-Robinson, J.M.1
Biemer-Huttmann, A.2
Purdie, D.M.3
Walsh, M.D.4
Simms, L.A.5
Biden, K.G.6
Young, J.P.7
Leggett, B.A.8
Jass, J.R.9
Radford-Smith, G.L.10
-
67
-
-
5544242524
-
Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis
-
Guidoboni, M.; Gafa, R.; Viel, A.; Doglioni, C.; Russo, A.; Santini, A.; Del Tin, L.; Macri, E.; Lanza, G.; Boiocchi, M.; et al. Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis. Am. J. Pathol. 2001, 159, 297-304.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 297-304
-
-
Guidoboni, M.1
Gafa, R.2
Viel, A.3
Doglioni, C.4
Russo, A.5
Santini, A.6
Del Tin, L.7
Macri, E.8
Lanza, G.9
Boiocchi, M.10
-
68
-
-
2342514891
-
Immune system and prognosis in colorectal cancer: A detailed immunohistochemical analysis
-
Menon, A.G.; Janssen-van Rhijn, C.M.; Morreau, H.; Putter, H.; Tollenaar, R.A.; van de Velde, C.J.; Fleuren, G.J.; Kuppen, P.J. Immune system and prognosis in colorectal cancer: A detailed immunohistochemical analysis. Lab. Invest. 2004, 84, 493-501.
-
(2004)
Lab. Invest.
, vol.84
, pp. 493-501
-
-
Menon, A.G.1
Janssen-van Rhijn, C.M.2
Morreau, H.3
Putter, H.4
Tollenaar, R.A.5
van de Velde, C.J.6
Fleuren, G.J.7
Kuppen, P.J.8
-
69
-
-
33748040054
-
Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma
-
Ogino, S.; Odze, R.D.; Kawasaki, T.; Brahmandam, M.; Kirkner, G.J.; Laird, P.W.; Loda, M.; Fuchs, C.S. Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma. Am. J. Surg. Pathol. 2006, 30, 1175-1183.
-
(2006)
Am. J. Surg. Pathol.
, vol.30
, pp. 1175-1183
-
-
Ogino, S.1
Odze, R.D.2
Kawasaki, T.3
Brahmandam, M.4
Kirkner, G.J.5
Laird, P.W.6
Loda, M.7
Fuchs, C.S.8
-
70
-
-
79955622234
-
Colorectal cancer prognosis depends on T-cell infiltration and molecular characteristics of the tumor
-
Dahlin, A.M.; Henriksson, M.L.; van Guelpen, B.; Stenling, R.; Oberg, A.; Rutegard, J.; Palmqvist, R. Colorectal cancer prognosis depends on T-cell infiltration and molecular characteristics of the tumor. Mod. Pathol. 2011, 24, 671-682.
-
(2011)
Mod. Pathol.
, vol.24
, pp. 671-682
-
-
Dahlin, A.M.1
Henriksson, M.L.2
van Guelpen, B.3
Stenling, R.4
Oberg, A.5
Rutegard, J.6
Palmqvist, R.7
-
71
-
-
82555191051
-
Cancer immunology-Analysis of host and tumor factors for personalized medicine
-
Ogino, S.; Galon, J.; Fuchs, C.S.; Dranoff, G. Cancer immunology-Analysis of host and tumor factors for personalized medicine. Nat. Rev. Clin. Oncol. 2011, 8, 711-719.
-
(2011)
Nat. Rev. Clin. Oncol.
, vol.8
, pp. 711-719
-
-
Ogino, S.1
Galon, J.2
Fuchs, C.S.3
Dranoff, G.4
-
72
-
-
84866852663
-
Cancer classification using the Immunoscore: A worldwide task force
-
Galon, J.; Pages, F.; Marincola, F.M.; Angell, H.K.; Thurin, M.; Lugli, A.; Zlobec, I.; Berger, A.; Bifulco, C.; Botti, G.; et al. Cancer classification using the Immunoscore: A worldwide task force. J. Transl. Med. 2012, 10, 205.
-
(2012)
J. Transl. Med.
, vol.10
, pp. 205
-
-
Galon, J.1
Pages, F.2
Marincola, F.M.3
Angell, H.K.4
Thurin, M.5
Lugli, A.6
Zlobec, I.7
Berger, A.8
Bifulco, C.9
Botti, G.10
-
73
-
-
77951814373
-
Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency
-
Goel, A.; Xicola, R.M.; Nguyen, T.P.; Doyle, B.J.; Sohn, V.R.; Bandipalliam, P.; Rozek, L.S.; Reyes, J.; Cordero, C.; Balaguer, F.; et al. Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency. Gastroenterology 2010, 138, 1854-1862.
-
(2010)
Gastroenterology
, vol.138
, pp. 1854-1862
-
-
Goel, A.1
Xicola, R.M.2
Nguyen, T.P.3
Doyle, B.J.4
Sohn, V.R.5
Bandipalliam, P.6
Rozek, L.S.7
Reyes, J.8
Cordero, C.9
Balaguer, F.10
-
74
-
-
84858276725
-
Epigenetics of colorectal cancer
-
Migheli, F.; Migliore, L. Epigenetics of colorectal cancer. Clin. Genet. 2012, 81, 312-318.
-
(2012)
Clin. Genet.
, vol.81
, pp. 312-318
-
-
Migheli, F.1
Migliore, L.2
-
76
-
-
84860841594
-
Epigenomic enhancer profiling defines a signature of colon cancer
-
Akhtar-Zaidi, B.; Cowper-Sal-lari, R.; Corradin, O.; Saiakhova, A.; Bartels, C.F.; Balasubramanian, D.; Myeroff, L.; Lutterbaugh, J.; Jarrar, A.; Kalady, M.F.; Willis, J.; et al. Epigenomic enhancer profiling defines a signature of colon cancer. Science 2012, 336, 736-739.
-
(2012)
Science
, vol.336
, pp. 736-739
-
-
Akhtar-Zaidi, B.1
Cowper-Sal-lari, R.2
Corradin, O.3
Saiakhova, A.4
Bartels, C.F.5
Balasubramanian, D.6
Myeroff, L.7
Lutterbaugh, J.8
Jarrar, A.9
Kalady, M.F.10
Willis, J.11
-
77
-
-
74049141478
-
Epigenetics in cancer
-
Sharma, S.; Kelly, T.K.; Jones, P.A. Epigenetics in cancer. Carcinogenesis 2010, 31, 27-36.
-
(2010)
Carcinogenesis
, vol.31
, pp. 27-36
-
-
Sharma, S.1
Kelly, T.K.2
Jones, P.A.3
-
78
-
-
0842278570
-
Epigenetic changes in colorectal cancer
-
Kondo, Y.; Issa, J.P. Epigenetic changes in colorectal cancer. Cancer Metastasis Rev. 2004, 23, 29-39.
-
(2004)
Cancer Metastasis Rev.
, vol.23
, pp. 29-39
-
-
Kondo, Y.1
Issa, J.P.2
-
79
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li, E.; Bestor, T.H.; Jaenisch, R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992, 69, 915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
80
-
-
0027348191
-
X chromosome inactivation and DNA methylation
-
Singer-Sam, J.; Riggs, A.D. X chromosome inactivation and DNA methylation. EXS 1993, 64, 358-384.
-
(1993)
EXS
, vol.64
, pp. 358-384
-
-
Singer-Sam, J.1
Riggs, A.D.2
-
81
-
-
0027378582
-
Role for DNA methylation in genomic imprinting
-
Li, E.; Beard, C.; Jaenisch, R. Role for DNA methylation in genomic imprinting. Nature 1993, 366, 362-365.
-
(1993)
Nature
, vol.366
, pp. 362-365
-
-
Li, E.1
Beard, C.2
Jaenisch, R.3
-
82
-
-
0036145156
-
Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours
-
Esteller, M.; Herman, J.G. Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours. J. Pathol. 2002, 196, 1-7.
-
(2002)
J. Pathol.
, vol.196
, pp. 1-7
-
-
Esteller, M.1
Herman, J.G.2
-
83
-
-
84876495060
-
CpG Island Methylation, Microsatellite Instability, and BRAF Mutations and Their Clinical Application in the Treatment of Colon Cancer
-
Wu, C.; Bekaii-Saab, T. CpG Island Methylation, Microsatellite Instability, and BRAF Mutations and Their Clinical Application in the Treatment of Colon Cancer. Chemother. Res. Pract. 2012, 2012, 359041.
-
(2012)
Chemother. Res. Pract.
, vol.2012
, pp. 359041
-
-
Wu, C.1
Bekaii-Saab, T.2
-
84
-
-
33644825262
-
Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage
-
Suzuki, K.; Suzuki, I.; Leodolter, A.; Alonso, S.; Horiuchi, S.; Yamashita, K.; Perucho, M. Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage. Cancer Cell 2006, 9, 199-207.
-
(2006)
Cancer Cell
, vol.9
, pp. 199-207
-
-
Suzuki, K.1
Suzuki, I.2
Leodolter, A.3
Alonso, S.4
Horiuchi, S.5
Yamashita, K.6
Perucho, M.7
-
85
-
-
0032480226
-
DNA hypomethylation leads to elevated mutation rates
-
Chen, R.Z.; Pettersson, U.; Beard, C.; Jackson-Grusby, L.; Jaenisch, R. DNA hypomethylation leads to elevated mutation rates. Nature 1998, 395, 89-93.
-
(1998)
Nature
, vol.395
, pp. 89-93
-
-
Chen, R.Z.1
Pettersson, U.2
Beard, C.3
Jackson-Grusby, L.4
Jaenisch, R.5
-
86
-
-
0030983076
-
DNA methylation and genetic instability in colorectal cancer cells
-
Lengauer, C.; Kinzler, K.W.; Vogelstein, B. DNA methylation and genetic instability in colorectal cancer cells. Proc. Natl. Acad. Sci. USA 1997, 94, 2545-2550.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2545-2550
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
87
-
-
79956304468
-
Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery
-
Ha, K.; Lee, G.E.; Palii, S.S.; Brown, K.D.; Takeda, Y.; Liu, K.; Bhalla, K.N.; Robertson, K.D. Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery. Hum. Mol. Genet. 2011, 20, 126-140.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 126-140
-
-
Ha, K.1
Lee, G.E.2
Palii, S.S.3
Brown, K.D.4
Takeda, Y.5
Liu, K.6
Bhalla, K.N.7
Robertson, K.D.8
-
88
-
-
59149084538
-
The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores
-
Irizarry, R.A.; Ladd-Acosta, C.; Wen, B.; Wu, Z.; Montano, C.; Onyango, P.; Cui, H.; Gabo, K.; Rongione, M.; Webster, M.; et al. The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores. Nat. Genet. 2009, 41, 178-186.
-
(2009)
Nat. Genet.
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
Wu, Z.4
Montano, C.5
Onyango, P.6
Cui, H.7
Gabo, K.8
Rongione, M.9
Webster, M.10
-
89
-
-
84867820420
-
Methylation subtypes and large-scale epigenetic alterations in gastric cancer
-
Milicic, A.; Harrison, L.A.; Goodlad, R.A.; Hardy, R.G.; Nicholson, A.M.; Presz, M.; Sieber, O.; Santander, S.; Pringle, J.H.; Mandir, N.; et al. Methylation subtypes and large-scale epigenetic alterations in gastric cancer. Sci. Transl. Med. 2012, 4, 156ra140.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Milicic, A.1
Harrison, L.A.2
Goodlad, R.A.3
Hardy, R.G.4
Nicholson, A.M.5
Presz, M.6
Sieber, O.7
Santander, S.8
Pringle, J.H.9
Mandir, N.10
-
90
-
-
26444473234
-
Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis
-
Yamada, Y.; Jackson-Grusby, L.; Linhart, H.; Meissner, A.; Eden, A.; Lin, H.; Jaenisch, R. Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. Proc. Natl. Acad. Sci. USA 2005, 102, 13580-13585.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 13580-13585
-
-
Yamada, Y.1
Jackson-Grusby, L.2
Linhart, H.3
Meissner, A.4
Eden, A.5
Lin, H.6
Jaenisch, R.7
-
91
-
-
84155165379
-
A distinct DNA methylation profile associated with microsatellite and chromosomal stable sporadic colorectal cancers
-
Silver, A.; Sengupta, N.; Propper, D.; Wilson, P.; Hagemann, T.; Patel, A.; Parker, A.; Ghosh, A.; Feakins, R.; Dorudi, S.; et al. A distinct DNA methylation profile associated with microsatellite and chromosomal stable sporadic colorectal cancers. Int. J. Cancer 2012, 130, 1082-1092.
-
(2012)
Int. J. Cancer
, vol.130
, pp. 1082-1092
-
-
Silver, A.1
Sengupta, N.2
Propper, D.3
Wilson, P.4
Hagemann, T.5
Patel, A.6
Parker, A.7
Ghosh, A.8
Feakins, R.9
Dorudi, S.10
-
92
-
-
34249789850
-
18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high
-
Ogino, S.; Kawasaki, T.; Kirkner, G.J.; Ohnishi, M.; Fuchs, C.S. 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high. BMC Cancer 2007, 7, 72.
-
(2007)
BMC Cancer
, vol.7
, pp. 72
-
-
Ogino, S.1
Kawasaki, T.2
Kirkner, G.J.3
Ohnishi, M.4
Fuchs, C.S.5
-
93
-
-
43049130760
-
LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer
-
Ogino, S.; Kawasaki, T.; Nosho, K.; Ohnishi, M.; Suemoto, Y.; Kirkner, G.J.; Fuchs, C.S. LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. Int. J. Cancer 2008, 122, 2767-2773.
-
(2008)
Int. J. Cancer
, vol.122
, pp. 2767-2773
-
-
Ogino, S.1
Kawasaki, T.2
Nosho, K.3
Ohnishi, M.4
Suemoto, Y.5
Kirkner, G.J.6
Fuchs, C.S.7
-
94
-
-
0027198976
-
Increased cytosine DNA-methyltransferase activity during colon cancer progression
-
Issa, J.P.; Vertino, P.M.; Wu, J.; Sazawal, S.; Celano, P.; Nelkin, B.D.; Hamilton, S.R.; Baylin, S.B. Increased cytosine DNA-methyltransferase activity during colon cancer progression. J. Natl. Cancer Inst. 1993, 85, 1235-1240.
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 1235-1240
-
-
Issa, J.P.1
Vertino, P.M.2
Wu, J.3
Sazawal, S.4
Celano, P.5
Nelkin, B.D.6
Hamilton, S.R.7
Baylin, S.B.8
-
95
-
-
66649097032
-
DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer
-
Nosho, K.; Shima, K.; Irahara, N.; Kure, S.; Baba, Y.; Kirkner, G.J.; Chen, L.; Gokhale, S.; Hazra, A.; Spiegelman, D.; et al. DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer. Clin. Cancer Res. 2009, 15, 3663-3671.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 3663-3671
-
-
Nosho, K.1
Shima, K.2
Irahara, N.3
Kure, S.4
Baba, Y.5
Kirkner, G.J.6
Chen, L.7
Gokhale, S.8
Hazra, A.9
Spiegelman, D.10
-
96
-
-
34548746357
-
Progressive up-regulation of genes encoding DNA methyltransferases in the colorectal adenoma-carcinoma sequence
-
Schmidt, W.M.; Sedivy, R.; Forstner, B.; Steger, G.G.; Zochbauer-Muller, S.; Mader, R.M. Progressive up-regulation of genes encoding DNA methyltransferases in the colorectal adenoma-carcinoma sequence. Mol. Carcinog. 2007, 46, 766-772.
-
(2007)
Mol. Carcinog.
, vol.46
, pp. 766-772
-
-
Schmidt, W.M.1
Sedivy, R.2
Forstner, B.3
Steger, G.G.4
Zochbauer-Muller, S.5
Mader, R.M.6
-
97
-
-
79952539026
-
Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression
-
Ibrahim, A.E.; Arends, M.J.; Silva, A.L.; Wyllie, A.H.; Greger, L.; Ito, Y.; Vowler, S.L.; Huang, T.H.; Tavare, S.; Murrell, A.; et al. Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression. Gut 2011, 60, 499-508.
-
(2011)
Gut
, vol.60
, pp. 499-508
-
-
Ibrahim, A.E.1
Arends, M.J.2
Silva, A.L.3
Wyllie, A.H.4
Greger, L.5
Ito, Y.6
Vowler, S.L.7
Huang, T.H.8
Tavare, S.9
Murrell, A.10
-
98
-
-
0032890965
-
The DNA methylation paradox
-
Jones, P.A. The DNA methylation paradox. Trends Genet. 1999, 15, 34-37.
-
(1999)
Trends Genet.
, vol.15
, pp. 34-37
-
-
Jones, P.A.1
-
99
-
-
0034929515
-
DNA methylation: An alternative pathway to cancer
-
Wajed, S.A.; Laird, P.W.; DeMeester, T.R. DNA methylation: An alternative pathway to cancer. Ann. Surg. 2001, 234, 10-20.
-
(2001)
Ann. Surg.
, vol.234
, pp. 10-20
-
-
Wajed, S.A.1
Laird, P.W.2
DeMeester, T.R.3
-
100
-
-
57749097557
-
DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells
-
McGough, J.M.; Yang, D.; Huang, S.; Georgi, D.; Hewitt, S.M.; Rocken, C.; Tanzer, M.; Ebert, M.P.; Liu, K. DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells. Mol. Cancer Res. 2008, 6, 1841-1851.
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 1841-1851
-
-
McGough, J.M.1
Yang, D.2
Huang, S.3
Georgi, D.4
Hewitt, S.M.5
Rocken, C.6
Tanzer, M.7
Ebert, M.P.8
Liu, K.9
-
101
-
-
34248230089
-
Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells
-
Yang, D.; Thangaraju, M.; Greeneltch, K.; Browning, D.D.; Schoenlein, P.V.; Tamura, T.; Ozato, K.; Ganapathy, V.; Abrams, S.I.; Liu, K. Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells. Cancer Res. 2007, 67, 3301-3309.
-
(2007)
Cancer Res.
, vol.67
, pp. 3301-3309
-
-
Yang, D.1
Thangaraju, M.2
Greeneltch, K.3
Browning, D.D.4
Schoenlein, P.V.5
Tamura, T.6
Ozato, K.7
Ganapathy, V.8
Abrams, S.I.9
Liu, K.10
-
102
-
-
80054790080
-
DNA methylation: Superior or subordinate in the epigenetic hierarchy?
-
Jin, B.; Li, Y.; Robertson, K.D. DNA methylation: Superior or subordinate in the epigenetic hierarchy? Genes Cancer 2011, 2, 607-617.
-
(2011)
Genes Cancer
, vol.2
, pp. 607-617
-
-
Jin, B.1
Li, Y.2
Robertson, K.D.3
-
103
-
-
0142153892
-
Eukaryotic methyl-CpG-binding domain proteins and chromatin modification
-
Hung, M.S.; Shen, C.K. Eukaryotic methyl-CpG-binding domain proteins and chromatin modification. Eukaryot. Cell 2003, 2, 841-846.
-
(2003)
Eukaryot. Cell
, vol.2
, pp. 841-846
-
-
Hung, M.S.1
Shen, C.K.2
-
104
-
-
80054790280
-
The Roles of the Methyl-CpG Binding Proteins in Cancer
-
Parry, L.; Clarke, A.R. The Roles of the Methyl-CpG Binding Proteins in Cancer. Genes Cancer 2011, 2, 618-630.
-
(2011)
Genes Cancer
, vol.2
, pp. 618-630
-
-
Parry, L.1
Clarke, A.R.2
-
105
-
-
0034807280
-
Methylation and colorectal cancer
-
Jubb, A.M.; Bell, S.M.; Quirke, P. Methylation and colorectal cancer. J. Pathol. 2001, 195, 111-134.
-
(2001)
J. Pathol.
, vol.195
, pp. 111-134
-
-
Jubb, A.M.1
Bell, S.M.2
Quirke, P.3
-
106
-
-
78649953952
-
Epigenetic silencing of peroxisome proliferator-activated receptor gamma is a biomarker for colorectal cancer progression and adverse patients' outcome
-
Pancione, M.; Sabatino, L.; Fucci, A.; Carafa, V.; Nebbioso, A.; Forte, N.; Febbraro, A.; Parente, D.; Ambrosino, C.; Normanno, N.; et al. Epigenetic silencing of peroxisome proliferator-activated receptor gamma is a biomarker for colorectal cancer progression and adverse patients' outcome. PLoS One 2010, 5, e14229.
-
(2010)
PLoS One
, vol.5
-
-
Pancione, M.1
Sabatino, L.2
Fucci, A.3
Carafa, V.4
Nebbioso, A.5
Forte, N.6
Febbraro, A.7
Parente, D.8
Ambrosino, C.9
Normanno, N.10
-
107
-
-
0038118300
-
MBD1, MBD2 and CGBP genes at chromosome 18q21 are infrequently mutated in human colon and lung cancers
-
Bader, S.; Walker, M.; McQueen, H.A.; Sellar, R.; Oei, E.; Wopereis, S.; Zhu, Y.; Peter, A.; Bird, A.P.; Harrison, D.J. MBD1, MBD2 and CGBP genes at chromosome 18q21 are infrequently mutated in human colon and lung cancers. Oncogene 2003, 22, 3506-3510.
-
(2003)
Oncogene
, vol.22
, pp. 3506-3510
-
-
Bader, S.1
Walker, M.2
McQueen, H.A.3
Sellar, R.4
Oei, E.5
Wopereis, S.6
Zhu, Y.7
Peter, A.8
Bird, A.P.9
Harrison, D.J.10
-
108
-
-
58749100088
-
Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer
-
Howard, J.H.; Frolov, A.; Tzeng, C.W.; Stewart, A.; Midzak, A.; Majmundar, A.; Godwin, A.; Heslin, M.; Bellacosa, A.; Arnoletti, J.P. Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer. Cancer Biol. Ther. 2009, 8, 94-100.
-
(2009)
Cancer Biol. Ther.
, vol.8
, pp. 94-100
-
-
Howard, J.H.1
Frolov, A.2
Tzeng, C.W.3
Stewart, A.4
Midzak, A.5
Majmundar, A.6
Godwin, A.7
Heslin, M.8
Bellacosa, A.9
Arnoletti, J.P.10
-
109
-
-
0032743063
-
The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability
-
Riccio, A.; Aaltonen, L.A.; Godwin, A.K.; Loukola, A.; Percesepe, A.; Salovaara, R.; Masciullo, V.; Genuardi, M.; Paravatou-Petsotas, M.; Bassi, D.E.; et al. The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability. Nat. Genet. 1999, 23, 266-268.
-
(1999)
Nat. Genet.
, vol.23
, pp. 266-268
-
-
Riccio, A.1
Aaltonen, L.A.2
Godwin, A.K.3
Loukola, A.4
Percesepe, A.5
Salovaara, R.6
Masciullo, V.7
Genuardi, M.8
Paravatou-Petsotas, M.9
Bassi, D.E.10
-
110
-
-
0033599013
-
Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency
-
Bader, S.; Walker, M.; Hendrich, B.; Bird, A.; Bird, C.; Hooper, M.; Wyllie, A. Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency. Oncogene 1999, 18, 8044-8047.
-
(1999)
Oncogene
, vol.18
, pp. 8044-8047
-
-
Bader, S.1
Walker, M.2
Hendrich, B.3
Bird, A.4
Bird, C.5
Hooper, M.6
Wyllie, A.7
-
111
-
-
0034543135
-
Most microsatellite unstable sporadic colorectal carcinomas carry MBD4 mutations
-
Bader, S.; Walker, M.; Harrison, D. Most microsatellite unstable sporadic colorectal carcinomas carry MBD4 mutations. Br. J. Cancer 2000, 83, 1646-1649.
-
(2000)
Br. J. Cancer
, vol.83
, pp. 1646-1649
-
-
Bader, S.1
Walker, M.2
Harrison, D.3
-
112
-
-
33847233256
-
A human cancer-associated truncation of MBD4 causes dominant negative impairment of DNA repair in colon cancer cells
-
Bader, S.A.; Walker, M.; Harrison, D.J. A human cancer-associated truncation of MBD4 causes dominant negative impairment of DNA repair in colon cancer cells. Br. J. Cancer 2007, 96, 660-666.
-
(2007)
Br. J. Cancer
, vol.96
, pp. 660-666
-
-
Bader, S.A.1
Walker, M.2
Harrison, D.J.3
-
113
-
-
0037135130
-
Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice
-
Millar, C.B.; Guy, J.; Sansom, O.J.; Selfridge, J.; MacDougall, E.; Hendrich, B.; Keightley, P.D.; Bishop, S.M.; Clarke, A.R.; Bird, A. Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice. Science 2002, 297, 403-405.
-
(2002)
Science
, vol.297
, pp. 403-405
-
-
Millar, C.B.1
Guy, J.2
Sansom, O.J.3
Selfridge, J.4
McDougall, E.5
Hendrich, B.6
Keightley, P.D.7
Bishop, S.M.8
Clarke, A.R.9
Bird, A.10
-
114
-
-
70349742486
-
DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer
-
Jin, B.; Yao, B.; Li, J.L.; Fields, C.R.; Delmas, A.L.; Liu, C.; Robertson, K.D. DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer. Cancer Res. 2009, 69, 7412-7421.
-
(2009)
Cancer Res.
, vol.69
, pp. 7412-7421
-
-
Jin, B.1
Yao, B.2
Li, J.L.3
Fields, C.R.4
Delmas, A.L.5
Liu, C.6
Robertson, K.D.7
-
115
-
-
32844459336
-
The Polycomb group protein EZH2 directly controls DNA methylation
-
Vire, E.; Brenner, C.; Deplus, R.; Blanchon, L.; Fraga, M.; Didelot, C.; Morey, L.; van Eynde, A.; Bernard, D.; Vanderwinden, J.M.; et al. The Polycomb group protein EZH2 directly controls DNA methylation. Nature 2006, 439, 871-874.
-
(2006)
Nature
, vol.439
, pp. 871-874
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
Blanchon, L.4
Fraga, M.5
Didelot, C.6
Morey, L.7
van Eynde, A.8
Bernard, D.9
Vanderwinden, J.M.10
-
116
-
-
68049137611
-
Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation
-
Mohammad, H.P.; Cai, Y.; McGarvey, K.M.; Easwaran, H.; van Neste, L.; Ohm, J.E.; O'Hagan, H.M.; Baylin, S.B. Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation. Cancer Res. 2009, 69, 6322-6330.
-
(2009)
Cancer Res.
, vol.69
, pp. 6322-6330
-
-
Mohammad, H.P.1
Cai, Y.2
McGarvey, K.M.3
Easwaran, H.4
van Neste, L.5
Ohm, J.E.6
O'Hagan, H.M.7
Baylin, S.B.8
-
117
-
-
67650088336
-
Clinicopathological implications of EpCAM expression in adenocarcinoma of the lung
-
Kim, Y.; Kim, H.S.; Cui, Z.Y.; Lee, H.S.; Ahn, J.S.; Park, C.K.; Park, K.; Ahn, M.J. Clinicopathological implications of EpCAM expression in adenocarcinoma of the lung. Anticancer Res. 2009, 29, 1817-1822.
-
(2009)
Anticancer Res.
, vol.29
, pp. 1817-1822
-
-
Kim, Y.1
Kim, H.S.2
Cui, Z.Y.3
Lee, H.S.4
Ahn, J.S.5
Park, C.K.6
Park, K.7
Ahn, M.J.8
-
118
-
-
33846569960
-
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
-
Ohm, J.E.; McGarvey, K.M.; Yu, X.; Cheng, L.; Schuebel, K.E.; Cope, L.; Mohammad, H.P.; Chen, W.; Daniel, V.C.; Yu, W.; et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat. Genet. 2007, 39, 237-242.
-
(2007)
Nat. Genet.
, vol.39
, pp. 237-242
-
-
Ohm, J.E.1
McGarvey, K.M.2
Yu, X.3
Cheng, L.4
Schuebel, K.E.5
Cope, L.6
Mohammad, H.P.7
Chen, W.8
Daniel, V.C.9
Yu, W.10
-
119
-
-
79960266611
-
EZH2 depletion blocks the proliferation of colon cancer cells
-
Fussbroich, B.; Wagener, N.; Macher-Goeppinger, S.; Benner, A.; Falth, M.; Sultmann, H.; Holzer, A.; Hoppe-Seyler, K.; Hoppe-Seyler, F. EZH2 depletion blocks the proliferation of colon cancer cells. PLoS One 2011, 6, e21651.
-
(2011)
PLoS One
, vol.6
-
-
Fussbroich, B.1
Wagener, N.2
McHer-Goeppinger, S.3
Benner, A.4
Falth, M.5
Sultmann, H.6
Holzer, A.7
Hoppe-Seyler, K.8
Hoppe-Seyler, F.9
-
120
-
-
0033946039
-
DNA mismatch repair genes and colorectal cancer
-
Wheeler, J.M.; Bodmer, W.F.; Mortensen, N.J. DNA mismatch repair genes and colorectal cancer. Gut 2000, 47, 148-153.
-
(2000)
Gut
, vol.47
, pp. 148-153
-
-
Wheeler, J.M.1
Bodmer, W.F.2
Mortensen, N.J.3
-
121
-
-
33749122904
-
Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer
-
Chan, T.L.; Yuen, S.T.; Kong, C.K.; Chan, Y.W.; Chan, A.S.; Ng, W.F.; Tsui, W.Y.; Lo, M.W.; Tam, W.Y.; Li, V.S.; et al. Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer. Nat. Genet. 2006, 38, 1178-1183.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1178-1183
-
-
Chan, T.L.1
Yuen, S.T.2
Kong, C.K.3
Chan, Y.W.4
Chan, A.S.5
Ng, W.F.6
Tsui, W.Y.7
Lo, M.W.8
Tam, W.Y.9
Li, V.S.10
-
122
-
-
58149144567
-
Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1
-
Ligtenberg, M.J.; Kuiper, R.P.; Chan, T.L.; Goossens, M.; Hebeda, K.M.; Voorendt, M.; Lee, T.Y.; Bodmer, D.; Hoenselaar, E.; Hendriks-Cornelissen, S.J.; et al. Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1. Nat. Genet. 2009, 41, 112-117.
-
(2009)
Nat. Genet.
, vol.41
, pp. 112-117
-
-
Ligtenberg, M.J.1
Kuiper, R.P.2
Chan, T.L.3
Goossens, M.4
Hebeda, K.M.5
Voorendt, M.6
Lee, T.Y.7
Bodmer, D.8
Hoenselaar, E.9
Hendriks-Cornelissen, S.J.10
-
123
-
-
84863011458
-
Unique DNA methylome profiles in CpG island methylator phenotype colon cancers
-
Xu, Y.; Hu, B.; Choi, A.J.; Gopalan, B.; Lee, B.H.; Kalady, M.F.; Church, J.M.; Ting, A.H. Unique DNA methylome profiles in CpG island methylator phenotype colon cancers. Genome Res. 2012, 22, 283-291.
-
(2012)
Genome Res.
, vol.22
, pp. 283-291
-
-
Xu, Y.1
Hu, B.2
Choi, A.J.3
Gopalan, B.4
Lee, B.H.5
Kalady, M.F.6
Church, J.M.7
Ting, A.H.8
-
124
-
-
36749025213
-
Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer
-
Shen, L.; Toyota, M.; Kondo, Y.; Lin, E.; Zhang, L.; Guo, Y.; Hernandez, N.S.; Chen, X.; Ahmed, S.; Konishi, K.; et al. Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. Proc. Natl. Acad. Sci. USA 2007, 104, 18654-18659.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 18654-18659
-
-
Shen, L.1
Toyota, M.2
Kondo, Y.3
Lin, E.4
Zhang, L.5
Guo, Y.6
Hernandez, N.S.7
Chen, X.8
Ahmed, S.9
Konishi, K.10
-
125
-
-
77952449085
-
Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features
-
Ang, P.W.; Loh, M.; Liem, N.; Lim, P.L.; Grieu, F.; Vaithilingam, A.; Platell, C.; Yong, W.P.; Iacopetta, B.; Soong, R. Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features. BMC Cancer 2010, 10, 227.
-
(2010)
BMC Cancer
, vol.10
, pp. 227
-
-
Ang, P.W.1
Loh, M.2
Liem, N.3
Lim, P.L.4
Grieu, F.5
Vaithilingam, A.6
Platell, C.7
Yong, W.P.8
Iacopetta, B.9
Soong, R.10
-
126
-
-
0142087630
-
Adverse prognostic effect of methylation in colorectal cancer is reversed by microsatellite instability
-
Ward, R.L.; Cheong, K.; Ku, S.L.; Meagher, A.; O'Connor, T.; Hawkins, N.J. Adverse prognostic effect of methylation in colorectal cancer is reversed by microsatellite instability. J. Clin. Oncol. 2003, 21, 3729-3736.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 3729-3736
-
-
Ward, R.L.1
Cheong, K.2
Ku, S.L.3
Meagher, A.4
O'Connor, T.5
Hawkins, N.J.6
-
127
-
-
0041524111
-
CpG island methylator phenotype is an independent predictor of survival benefit from 5-fluorouracil in stage III colorectal cancer
-
Van Rijnsoever, M.; Elsaleh, H.; Joseph, D.; McCaul, K.; Iacopetta, B. CpG island methylator phenotype is an independent predictor of survival benefit from 5-fluorouracil in stage III colorectal cancer. Clin. Cancer Res. 2003, 9, 2898-2903.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 2898-2903
-
-
van Rijnsoever, M.1
Elsaleh, H.2
Joseph, D.3
McCaul, K.4
Iacopetta, B.5
-
128
-
-
34247638013
-
CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma
-
Ogino, S.; Meyerhardt, J.A.; Kawasaki, T.; Clark, J.W.; Ryan, D.P.; Kulke, M.H.; Enzinger, P.C.; Wolpin, B.M.; Loda, M.; Fuchs, C.S. CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma. Virchows Arch. 2007, 450, 529-537.
-
(2007)
Virchows Arch.
, vol.450
, pp. 529-537
-
-
Ogino, S.1
Meyerhardt, J.A.2
Kawasaki, T.3
Clark, J.W.4
Ryan, D.P.5
Kulke, M.H.6
Enzinger, P.C.7
Wolpin, B.M.8
Loda, M.9
Fuchs, C.S.10
-
129
-
-
38149135181
-
Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation
-
Lee, S.; Cho, N.Y.; Choi, M.; Yoo, E.J.; Kim, J.H.; Kang, G.H. Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation. Pathol. Int. 2008, 58, 104-113.
-
(2008)
Pathol. Int.
, vol.58
, pp. 104-113
-
-
Lee, S.1
Cho, N.Y.2
Choi, M.3
Yoo, E.J.4
Kim, J.H.5
Kang, G.H.6
-
130
-
-
58249089525
-
CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer
-
Ogino, S.; Nosho, K.; Kirkner, G.J.; Kawasaki, T.; Meyerhardt, J.A.; Loda, M.; Giovannucci, E.L.; Fuchs, C.S. CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut 2009, 58, 90-96.
-
(2009)
Gut
, vol.58
, pp. 90-96
-
-
Ogino, S.1
Nosho, K.2
Kirkner, G.J.3
Kawasaki, T.4
Meyerhardt, J.A.5
Loda, M.6
Giovannucci, E.L.7
Fuchs, C.S.8
-
131
-
-
54249165951
-
Hypermethylator phenotype in sporadic colon cancer: Study on a population-based series of 582 cases
-
Barault, L.; Charon-Barra, C.; Jooste, V.; de la Vega, M.F.; Martin, L.; Roignot, P.; Rat, P.; Bouvier, A.M.; Laurent-Puig, P.; Faivre, J.; et al. Hypermethylator phenotype in sporadic colon cancer: Study on a population-based series of 582 cases. Cancer Res. 2008, 68, 8541-8546.
-
(2008)
Cancer Res.
, vol.68
, pp. 8541-8546
-
-
Barault, L.1
Charon-Barra, C.2
Jooste, V.3
de la Vega, M.F.4
Martin, L.5
Roignot, P.6
Rat, P.7
Bouvier, A.M.8
Laurent-Puig, P.9
Faivre, J.10
-
132
-
-
79953217628
-
5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer
-
Jover, R.; Nguyen, T.P.; Perez-Carbonell, L.; Zapater, P.; Paya, A.; Alenda, C.; Rojas, E.; Cubiella, J.; Balaguer, F.; Morillas, J.D.; et al. 5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer. Gastroenterology 2011, 140, 1174-1181.
-
(2011)
Gastroenterology
, vol.140
, pp. 1174-1181
-
-
Jover, R.1
Nguyen, T.P.2
Perez-Carbonell, L.3
Zapater, P.4
Paya, A.5
Alenda, C.6
Rojas, E.7
Cubiella, J.8
Balaguer, F.9
Morillas, J.D.10
-
133
-
-
0031004175
-
Genetic instability in colorectal cancers
-
Lengauer, C.; Kinzler, K.W.; Vogelstein, B. Genetic instability in colorectal cancers. Nature 1997, 386, 623-627.
-
(1997)
Nature
, vol.386
, pp. 623-627
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
134
-
-
0028830692
-
Genomic imprinting proposed as a surveillance mechanism for chromosome loss
-
Thomas, J.H. Genomic imprinting proposed as a surveillance mechanism for chromosome loss. Proc. Natl. Acad. Sci. USA 1995, 92, 480-482.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 480-482
-
-
Thomas, J.H.1
-
135
-
-
0031018674
-
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
-
Rampino, N.; Yamamoto, H.; Ionov, Y.; Li, Y.; Sawai, H.; Reed, J.C.; Perucho, M. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science 1997, 275, 967-969.
-
(1997)
Science
, vol.275
, pp. 967-969
-
-
Rampino, N.1
Yamamoto, H.2
Ionov, Y.3
Li, Y.4
Sawai, H.5
Reed, J.C.6
Perucho, M.7
-
136
-
-
0033168064
-
Apoptosis induced by overexpression of hMSH2 or hMLH1
-
Zhang, H.; Richards, B.; Wilson, T.; Lloyd, M.; Cranston, A.; Thorburn, A.; Fishel, R.; Meuth, M. Apoptosis induced by overexpression of hMSH2 or hMLH1. Cancer Res. 1999, 59, 3021-3027.
-
(1999)
Cancer Res.
, vol.59
, pp. 3021-3027
-
-
Zhang, H.1
Richards, B.2
Wilson, T.3
Lloyd, M.4
Cranston, A.5
Thorburn, A.6
Fishel, R.7
Meuth, M.8
-
137
-
-
84856549042
-
Genome-scale analysis of aberrant DNA methylation in colorectal cancer
-
Hinoue, T.; Weisenberger, D.J.; Lange, C.P.; Shen, H.; Byun, H.M.; van Den Berg, D.; Malik, S.; Pan, F.; Noushmehr, H.; van Dijk, C.M.; et al. Genome-scale analysis of aberrant DNA methylation in colorectal cancer. Genome Res. 2012, 22, 271-282.
-
(2012)
Genome Res.
, vol.22
, pp. 271-282
-
-
Hinoue, T.1
Weisenberger, D.J.2
Lange, C.P.3
Shen, H.4
Byun, H.M.5
van Den Berg, D.6
Malik, S.7
Pan, F.8
Noushmehr, H.9
van Dijk, C.M.10
-
138
-
-
33749069927
-
CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: Possible associations with male sex and KRAS mutations
-
Ogino, S.; Kawasaki, T.; Kirkner, G.J.; Loda, M.; Fuchs, C.S. CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: Possible associations with male sex and KRAS mutations. J. Mol. Diagn. 2006, 8, 582-588.
-
(2006)
J. Mol. Diagn.
, vol.8
, pp. 582-588
-
-
Ogino, S.1
Kawasaki, T.2
Kirkner, G.J.3
Loda, M.4
Fuchs, C.S.5
-
139
-
-
0035328527
-
Accelerated age-related CpG island methylation in ulcerative colitis
-
Issa, J.P.; Ahuja, N.; Toyota, M.; Bronner, M.P.; Brentnall, T.A. Accelerated age-related CpG island methylation in ulcerative colitis. Cancer Res. 2001, 61, 3573-3577.
-
(2001)
Cancer Res.
, vol.61
, pp. 3573-3577
-
-
Issa, J.P.1
Ahuja, N.2
Toyota, M.3
Bronner, M.P.4
Brentnall, T.A.5
-
140
-
-
80755173982
-
Relative role of methylator and tumor suppressor pathways in ulcerative colitis-associated colon cancer
-
Sanchez, J.A.; Dejulius, K.L.; Bronner, M.; Church, J.M.; Kalady, M.F. Relative role of methylator and tumor suppressor pathways in ulcerative colitis-associated colon cancer. Inflamm. Bowel Dis. 2011, 17, 1966-1970.
-
(2011)
Inflamm. Bowel Dis.
, vol.17
, pp. 1966-1970
-
-
Sanchez, J.A.1
Dejulius, K.L.2
Bronner, M.3
Church, J.M.4
Kalady, M.F.5
-
141
-
-
84858700966
-
Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers
-
Olaru, A.V.; Cheng, Y.; Agarwal, R.; Yang, J.; David, S.; Abraham, J.M.; Yu, W.; Kwon, J.H.; Lazarev, M.; Brant, S.R.; et al. Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers. Inflamm. Bowel Dis. 2012, 18, 641-648.
-
(2012)
Inflamm. Bowel Dis.
, vol.18
, pp. 641-648
-
-
Olaru, A.V.1
Cheng, Y.2
Agarwal, R.3
Yang, J.4
David, S.5
Abraham, J.M.6
Yu, W.7
Kwon, J.H.8
Lazarev, M.9
Brant, S.R.10
-
142
-
-
34247273521
-
Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias
-
Konishi, K.; Shen, L.; Wang, S.; Meltzer, S.J.; Harpaz, N.; Issa, J.P. Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias. Gastroenterology 2007, 132, 1254-1260.
-
(2007)
Gastroenterology
, vol.132
, pp. 1254-1260
-
-
Konishi, K.1
Shen, L.2
Wang, S.3
Meltzer, S.J.4
Harpaz, N.5
Issa, J.P.6
-
143
-
-
0034282793
-
Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1
-
Fleisher, A.S.; Esteller, M.; Harpaz, N.; Leytin, A.; Rashid, A.; Xu, Y.; Liang, J.; Stine, O.C.; Yin, J.; Zou, T.T.; et al. Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1. Cancer Res. 2000, 60, 4864-4868.
-
(2000)
Cancer Res.
, vol.60
, pp. 4864-4868
-
-
Fleisher, A.S.1
Esteller, M.2
Harpaz, N.3
Leytin, A.4
Rashid, A.5
Xu, Y.6
Liang, J.7
Stine, O.C.8
Yin, J.9
Zou, T.T.10
-
144
-
-
84866707635
-
A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer
-
Antelo, M.; Balaguer, F.; Shia, J.; Shen, Y.; Hur, K.; Moreira, L.; Cuatrecasas, M.; Bujanda, L.; Giraldez, M.D.; Takahashi, M.; et al. A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer. PLoS One 2012, 7, e45357.
-
(2012)
PLoS One
, vol.7
-
-
Antelo, M.1
Balaguer, F.2
Shia, J.3
Shen, Y.4
Hur, K.5
Moreira, L.6
Cuatrecasas, M.7
Bujanda, L.8
Giraldez, M.D.9
Takahashi, M.10
-
145
-
-
36849059066
-
LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability
-
Estecio, M.R.; Gharibyan, V.; Shen, L.; Ibrahim, A.E.; Doshi, K.; He, R.; Jelinek, J.; Yang, A.S.; Yan, P.S.; Huang, T.H.; et al. LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability. PLoS One 2007, 2, e399.
-
(2007)
PLoS One
, vol.2
-
-
Estecio, M.R.1
Gharibyan, V.2
Shen, L.3
Ibrahim, A.E.4
Doshi, K.5
He, R.6
Jelinek, J.7
Yang, A.S.8
Yan, P.S.9
Huang, T.H.10
-
146
-
-
57349138824
-
A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer
-
Ogino, S.; Nosho, K.; Kirkner, G.J.; Kawasaki, T.; Chan, A.T.; Schernhammer, E.S.; Giovannucci, E.L.; Fuchs, C.S. A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer. J. Natl. Cancer Inst. 2008, 100, 1734-1738.
-
(2008)
J. Natl. Cancer Inst.
, vol.100
, pp. 1734-1738
-
-
Ogino, S.1
Nosho, K.2
Kirkner, G.J.3
Kawasaki, T.4
Chan, A.T.5
Schernhammer, E.S.6
Giovannucci, E.L.7
Fuchs, C.S.8
-
147
-
-
77952712959
-
Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors
-
Baba, Y.; Huttenhower, C.; Nosho, K.; Tanaka, N.; Shima, K.; Hazra, A.; Schernhammer, E.S.; Hunter, D.J.; Giovannucci, E.L.; Fuchs, C.S.; et al. Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors. Mol. Cancer 2010, 9, 125.
-
(2010)
Mol. Cancer
, vol.9
, pp. 125
-
-
Baba, Y.1
Huttenhower, C.2
Nosho, K.3
Tanaka, N.4
Shima, K.5
Hazra, A.6
Schernhammer, E.S.7
Hunter, D.J.8
Giovannucci, E.L.9
Fuchs, C.S.10
-
148
-
-
79955397102
-
DNA methylation predicts recurrence from resected stage III proximal colon cancer
-
Ahn, J.B.; Chung, W.B.; Maeda, O.; Shin, S.J.; Kim, H.S.; Chung, H.C.; Kim, N.K.; Issa, J.P. DNA methylation predicts recurrence from resected stage III proximal colon cancer. Cancer 2011, 117, 1847-1854.
-
(2011)
Cancer
, vol.117
, pp. 1847-1854
-
-
Ahn, J.B.1
Chung, W.B.2
Maeda, O.3
Shin, S.J.4
Kim, H.S.5
Chung, H.C.6
Kim, N.K.7
Issa, J.P.8
-
149
-
-
84868208197
-
Clinical outcomes of patients with microsatellite-unstable colorectal carcinomas depend on L1 methylation level
-
Rhee, Y.Y.; Kim, M.J.; Bae, J.M.; Koh, J.M.; Cho, N.Y.; Juhnn, Y.S.; Kim, D.; Kang, G.H. Clinical outcomes of patients with microsatellite-unstable colorectal carcinomas depend on L1 methylation level. Ann. Surg. Oncol. 2012, 19, 3441-3448.
-
(2012)
Ann. Surg. Oncol.
, vol.19
, pp. 3441-3448
-
-
Rhee, Y.Y.1
Kim, M.J.2
Bae, J.M.3
Koh, J.M.4
Cho, N.Y.5
Juhnn, Y.S.6
Kim, D.7
Kang, G.H.8
-
150
-
-
84872587403
-
Prospective study of family history and colorectal cancer risk by tumor LINE-1 methylation level
-
Ogino, S.; Nishihara, R.; Lochhead, P.; Imamura, Y.; Kuchiba, A.; Morikawa, T.; Yamauchi, M.; Liao, X.; Qian, Z.R.; Sun, R.; et al. Prospective study of family history and colorectal cancer risk by tumor LINE-1 methylation level. J. Natl. Cancer Inst. 2013, 105, 130-140.
-
(2013)
J. Natl. Cancer Inst.
, vol.105
, pp. 130-140
-
-
Ogino, S.1
Nishihara, R.2
Lochhead, P.3
Imamura, Y.4
Kuchiba, A.5
Morikawa, T.6
Yamauchi, M.7
Liao, X.8
Qian, Z.R.9
Sun, R.10
-
151
-
-
84859893371
-
Histone methylation: A dynamic mark in health, disease and inheritance
-
Greer, E.L.; Shi, Y. Histone methylation: A dynamic mark in health, disease and inheritance. Nat. Rev. Genet. 2012, 13, 343-357.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 343-357
-
-
Greer, E.L.1
Shi, Y.2
-
152
-
-
84861183715
-
Global histone modification of histone H3 in colorectal cancer and its precursor lesions
-
Nakazawa, T.; Kondo, T.; Ma, D.; Niu, D.; Mochizuki, K.; Kawasaki, T.; Yamane, T.; Iino, H.; Fujii, H.; Katoh, R. Global histone modification of histone H3 in colorectal cancer and its precursor lesions. Hum. Pathol. 2012, 43, 834-842.
-
(2012)
Hum. Pathol.
, vol.43
, pp. 834-842
-
-
Nakazawa, T.1
Kondo, T.2
Ma, D.3
Niu, D.4
Mochizuki, K.5
Kawasaki, T.6
Yamane, T.7
Iino, H.8
Fujii, H.9
Katoh, R.10
-
153
-
-
84861937510
-
Silencing of Wnt5a during colon cancer metastasis involves histone modifications
-
Li, Q.; Chen, H. Silencing of Wnt5a during colon cancer metastasis involves histone modifications. Epigenetics 2012, 7, 551-558.
-
(2012)
Epigenetics
, vol.7
, pp. 551-558
-
-
Li, Q.1
Chen, H.2
-
154
-
-
84876207842
-
Transcriptional regulation by histone modifications: Towards a theory of chromatin re-organization during stem cell differentiation
-
Binder, H.; Steiner, L.; Przybilla, J.; Rohlf, T.; Prohaska, S.; Galle, J. Transcriptional regulation by histone modifications: Towards a theory of chromatin re-organization during stem cell differentiation. Phys. Biol. 2013, 10, 026006.
-
(2013)
Phys. Biol.
, vol.10
, pp. 026006
-
-
Binder, H.1
Steiner, L.2
Przybilla, J.3
Rohlf, T.4
Prohaska, S.5
Galle, J.6
-
155
-
-
79952534189
-
Regulation of chromatin by histone modifications
-
Bannister, A.J.; Kouzarides, T. Regulation of chromatin by histone modifications. Cell Res. 2011, 21, 381-395.
-
(2011)
Cell Res.
, vol.21
, pp. 381-395
-
-
Bannister, A.J.1
Kouzarides, T.2
-
156
-
-
0034051227
-
Acetylation of histones and transcription-related factors
-
Sterner, D.E.; Berger, S.L. Acetylation of histones and transcription-related factors. Microbiol. Mol. Biol. Rev. 2000, 64, 435-459.
-
(2000)
Microbiol. Mol. Biol. Rev.
, vol.64
, pp. 435-459
-
-
Sterner, D.E.1
Berger, S.L.2
-
157
-
-
18844413266
-
Acetylation in histone H3 globular domain regulates gene expression in yeast
-
Xu, F.; Zhang, K.; Grunstein, M. Acetylation in histone H3 globular domain regulates gene expression in yeast. Cell 2005, 121, 375-385.
-
(2005)
Cell
, vol.121
, pp. 375-385
-
-
Xu, F.1
Zhang, K.2
Grunstein, M.3
-
158
-
-
33846796258
-
Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication
-
Han, J.; Zhou, H.; Horazdovsky, B.; Zhang, K.; Xu, R.M.; Zhang, Z. Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication. Science 2007, 315, 653-655.
-
(2007)
Science
, vol.315
, pp. 653-655
-
-
Han, J.1
Zhou, H.2
Horazdovsky, B.3
Zhang, K.4
Xu, R.M.5
Zhang, Z.6
-
159
-
-
33846818840
-
Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56
-
Driscoll, R.; Hudson, A.; Jackson, S.P. Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56. Science 2007, 315, 649-652.
-
(2007)
Science
, vol.315
, pp. 649-652
-
-
Driscoll, R.1
Hudson, A.2
Jackson, S.P.3
-
160
-
-
33846023720
-
Rtt109 is required for proper H3K56 acetylation: A chromatin mark associated with the elongating RNA polymerase II
-
Schneider, J.; Bajwa, P.; Johnson, F.C.; Bhaumik, S.R.; Shilatifard, A. Rtt109 is required for proper H3K56 acetylation: A chromatin mark associated with the elongating RNA polymerase II. J. Biol. Chem. 2006, 281, 37270-37274.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 37270-37274
-
-
Schneider, J.1
Bajwa, P.2
Johnson, F.C.3
Bhaumik, S.R.4
Shilatifard, A.5
-
161
-
-
33646550204
-
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
-
Vaquero, A.; Scher, M.B.; Lee, D.H.; Sutton, A.; Cheng, H.L.; Alt, F.W.; Serrano, L.; Sternglanz, R.; Reinberg, D. SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. Genes Dev. 2006, 20, 1256-1261.
-
(2006)
Genes Dev.
, vol.20
, pp. 1256-1261
-
-
Vaquero, A.1
Scher, M.B.2
Lee, D.H.3
Sutton, A.4
Cheng, H.L.5
Alt, F.W.6
Serrano, L.7
Sternglanz, R.8
Reinberg, D.9
-
162
-
-
41549159879
-
Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: Specific role of class I histone deacetylases in vitro and in vivo
-
Weichert, W.; Roske, A.; Niesporek, S.; Noske, A.; Buckendahl, A.C.; Dietel, M.; Gekeler, V.; Boehm, M.; Beckers, T.; Denkert, C. Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: Specific role of class I histone deacetylases in vitro and in vivo. Clin. Cancer Res. 2008, 14, 1669-1677.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 1669-1677
-
-
Weichert, W.1
Roske, A.2
Niesporek, S.3
Noske, A.4
Buckendahl, A.C.5
Dietel, M.6
Gekeler, V.7
Boehm, M.8
Beckers, T.9
Denkert, C.10
-
163
-
-
70149103990
-
Global histone H4 acetylation and HDAC2 expression in colon adenoma and carcinoma
-
Ashktorab, H.; Belgrave, K.; Hosseinkhah, F.; Brim, H.; Nouraie, M.; Takkikto, M.; Hewitt, S.; Lee, E.L.; Dashwood, R.H.; Smoot, D. Global histone H4 acetylation and HDAC2 expression in colon adenoma and carcinoma. Dig. Dis. Sci. 2009, 54, 2109-2117.
-
(2009)
Dig. Dis. Sci.
, vol.54
, pp. 2109-2117
-
-
Ashktorab, H.1
Belgrave, K.2
Hosseinkhah, F.3
Brim, H.4
Nouraie, M.5
Takkikto, M.6
Hewitt, S.7
Lee, E.L.8
Dashwood, R.H.9
Smoot, D.10
-
164
-
-
36049045474
-
Expression of HDAC1 and CBP/p300 in human colorectal carcinomas
-
Ishihama, K.; Yamakawa, M.; Semba, S.; Takeda, H.; Kawata, S.; Kimura, S.; Kimura, W. Expression of HDAC1 and CBP/p300 in human colorectal carcinomas. J. Clin. Pathol. 2007, 60, 1205-1210.
-
(2007)
J. Clin. Pathol.
, vol.60
, pp. 1205-1210
-
-
Ishihama, K.1
Yamakawa, M.2
Semba, S.3
Takeda, H.4
Kawata, S.5
Kimura, S.6
Kimura, W.7
-
165
-
-
67650691722
-
SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer
-
Nosho, K.; Shima, K.; Irahara, N.; Kure, S.; Firestein, R.; Baba, Y.; Toyoda, S.; Chen, L.; Hazra, A.; Giovannucci, E.L.; et al. SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. Mod. Pathol. 2009, 22, 922-932.
-
(2009)
Mod. Pathol.
, vol.22
, pp. 922-932
-
-
Nosho, K.1
Shima, K.2
Irahara, N.3
Kure, S.4
Firestein, R.5
Baba, Y.6
Toyoda, S.7
Chen, L.8
Hazra, A.9
Giovannucci, E.L.10
-
166
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl, B.D.; Allis, C.D. The language of covalent histone modifications. Nature 2000, 403, 41-45.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
167
-
-
33846019277
-
Methylation of lysine 4 on histone H3: Intricacy of writing and reading a single epigenetic mark
-
Ruthenburg, A.J.; Allis, C.D.; Wysocka, J. Methylation of lysine 4 on histone H3: Intricacy of writing and reading a single epigenetic mark. Mol. Cell 2007, 25, 15-30.
-
(2007)
Mol. Cell
, vol.25
, pp. 15-30
-
-
Ruthenburg, A.J.1
Allis, C.D.2
Wysocka, J.3
-
168
-
-
33947513027
-
Regulation of histone methylation by demethylimination and demethylation
-
Klose, R.J.; Zhang, Y. Regulation of histone methylation by demethylimination and demethylation. Nat. Rev. Mol. Cell Biol. 2007, 8, 307-318.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 307-318
-
-
Klose, R.J.1
Zhang, Y.2
-
169
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski, A.; Cuddapah, S.; Cui, K.; Roh, T.Y.; Schones, D.E.; Wang, Z.; Wei, G.; Chepelev, I.; Zhao, K. High-resolution profiling of histone methylations in the human genome. Cell 2007, 129, 823-837.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
170
-
-
79959960773
-
The diverse functions of Dot1 and H3K79 methylation
-
Nguyen, A.T.; Zhang, Y. The diverse functions of Dot1 and H3K79 methylation. Genes Dev. 2011, 25, 1345-1358.
-
(2011)
Genes Dev.
, vol.25
, pp. 1345-1358
-
-
Nguyen, A.T.1
Zhang, Y.2
-
171
-
-
33845451555
-
Profile of histone lysine methylation across transcribed mammalian chromatin
-
Vakoc, C.R.; Sachdeva, M.M.; Wang, H.; Blobel, G.A. Profile of histone lysine methylation across transcribed mammalian chromatin. Mol. Cell Biol. 2006, 26, 9185-9195.
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 9185-9195
-
-
Vakoc, C.R.1
Sachdeva, M.M.2
Wang, H.3
Blobel, G.A.4
-
172
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B.E.; Mikkelsen, T.S.; Xie, X.; Kamal, M.; Huebert, D.J.; Cuff, J.; Fry, B.; Meissner, A.; Wernig, M.; Plath, K.; et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006, 125, 315-326.
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
-
173
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen, T.S.; Ku, M.; Jaffe, D.B.; Issac, B.; Lieberman, E.; Giannoukos, G.; Alvarez, P.; Brockman, W.; Kim, T.K.; Koche, R.P.; et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 2007, 448, 553-560.
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
Issac, B.4
Lieberman, E.5
Giannoukos, G.6
Alvarez, P.7
Brockman, W.8
Kim, T.K.9
Koche, R.P.10
-
174
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides, T. Chromatin modifications and their function. Cell 2007, 128, 693-705.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
175
-
-
78649920369
-
The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasis
-
Mahmoudi, T.; Boj, S.F.; Hatzis, P.; Li, V.S.; Taouatas, N.; Vries, R.G.; Teunissen, H.; Begthel, H.; Korving, J.; Mohammed, S.; et al. The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasis. PLoS Biol. 2010, 8, e1000539.
-
(2010)
PLoS Biol.
, vol.8
-
-
Mahmoudi, T.1
Boj, S.F.2
Hatzis, P.3
Li, V.S.4
Taouatas, N.5
Vries, R.G.6
Teunissen, H.7
Begthel, H.8
Korving, J.9
Mohammed, S.10
-
176
-
-
55949136562
-
Roles of the EZH2 histone methyltransferase in cancer epigenetics
-
Simon, J.A.; Lange, C.A. Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat. Res. 2008, 647, 21-29.
-
(2008)
Mutat. Res.
, vol.647
, pp. 21-29
-
-
Simon, J.A.1
Lange, C.A.2
-
177
-
-
70350500219
-
Polycomb group proteins: Navigators of lineage pathways led astray in cancer
-
Bracken, A.P.; Helin, K. Polycomb group proteins: Navigators of lineage pathways led astray in cancer. Nat. Rev. Cancer 2009, 9, 773-784.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 773-784
-
-
Bracken, A.P.1
Helin, K.2
-
178
-
-
58149214373
-
Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2
-
Ougolkov, A.V.; Bilim, V.N.; Billadeau, D.D. Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2. Clin. Cancer Res. 2008, 14, 6790-6796.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 6790-6796
-
-
Ougolkov, A.V.1
Bilim, V.N.2
Billadeau, D.D.3
-
179
-
-
60149096212
-
Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1
-
Gonzalez, M.E.; Li, X.; Toy, K.; DuPrie, M.; Ventura, A.C.; Banerjee, M.; Ljungman, M.; Merajver, S.D.; Kleer, C.G. Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1. Oncogene 2009, 28, 843-853.
-
(2009)
Oncogene
, vol.28
, pp. 843-853
-
-
Gonzalez, M.E.1
Li, X.2
Toy, K.3
DuPrie, M.4
Ventura, A.C.5
Banerjee, M.6
Ljungman, M.7
Merajver, S.D.8
Kleer, C.G.9
-
180
-
-
35748937338
-
Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer
-
Yu, J.; Cao, Q.; Mehra, R.; Laxman, B.; Yu, J.; Tomlins, S.A.; Creighton, C.J.; Dhanasekaran, S.M.; Shen, R.; Chen, G.; et al. Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer. Cancer Cell 2007, 12, 419-431.
-
(2007)
Cancer Cell
, vol.12
, pp. 419-431
-
-
Yu, J.1
Cao, Q.2
Mehra, R.3
Laxman, B.4
Yu, J.5
Tomlins, S.A.6
Creighton, C.J.7
Dhanasekaran, S.M.8
Shen, R.9
Chen, G.10
-
181
-
-
77951539195
-
Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon
-
Natarajan, T.G.; Kallakury, B.V.; Sheehan, C.E.; Bartlett, M.B.; Ganesan, N.; Preet, A.; Ross, J.S.; Fitzgerald, K.T. Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon. Cancer Cell Int. 2010, 10, 13.
-
(2010)
Cancer Cell Int.
, vol.10
, pp. 13
-
-
Natarajan, T.G.1
Kallakury, B.V.2
Sheehan, C.E.3
Bartlett, M.B.4
Ganesan, N.5
Preet, A.6
Ross, J.S.7
Fitzgerald, K.T.8
-
182
-
-
35348914451
-
Association of the SUV39H1 histone methyltransferase with the DNA methyltransferase 1 at mRNA expression level in primary colorectal cancer
-
Kang, M.Y.; Lee, B.B.; Kim, Y.H.; Chang, D.K.; Kyu Park, S.; Chun, H.K.; Song, S.Y.; Park, J.; Kim, D.H. Association of the SUV39H1 histone methyltransferase with the DNA methyltransferase 1 at mRNA expression level in primary colorectal cancer. Int. J. Cancer 2007, 121, 2192-2197.
-
(2007)
Int. J. Cancer
, vol.121
, pp. 2192-2197
-
-
Kang, M.Y.1
Lee, B.B.2
Kim, Y.H.3
Chang, D.K.4
Kyu Park, S.5
Chun, H.K.6
Song, S.Y.7
Park, J.8
Kim, D.H.9
-
183
-
-
84883798471
-
PcG proteins, DNA methylation, and gene repression by chromatin looping
-
Tiwari, V.K.; McGarvey, K.M.; Licchesi, J.D.; Ohm, J.E.; Herman, J.G.; Schubeler, D.; Baylin, S.B. PcG proteins, DNA methylation, and gene repression by chromatin looping. PLoS Biol. 2008, 6, 2911-2927.
-
(2008)
PLoS Biol.
, vol.6
, pp. 2911-2927
-
-
Tiwari, V.K.1
McGarvey, K.M.2
Licchesi, J.D.3
Ohm, J.E.4
Herman, J.G.5
Schubeler, D.6
Baylin, S.B.7
-
184
-
-
33747628074
-
Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues
-
Bandres, E.; Cubedo, E.; Agirre, X.; Malumbres, R.; Zarate, R.; Ramirez, N.; Abajo, A.; Navarro, A.; Moreno, I.; Monzo, M.; et al. Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol. Cancer 2006, 5, 29.
-
(2006)
Mol. Cancer
, vol.5
, pp. 29
-
-
Bandres, E.1
Cubedo, E.2
Agirre, X.3
Malumbres, R.4
Zarate, R.5
Ramirez, N.6
Abajo, A.7
Navarro, A.8
Moreno, I.9
Monzo, M.10
-
185
-
-
33747628074
-
Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues
-
Bandres, E.; Cubedo, E.; Agirre, X.; Malumbres, R.; Zarate, R.; Ramirez, N.; Abajo, A.; Navarro, A.; Moreno, I.; Monzo, M.; et al. Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol. Cancer 2006, 5, 29.
-
(2006)
Mol. Cancer
, vol.5
, pp. 29
-
-
Bandres, E.1
Cubedo, E.2
Agirre, X.3
Malumbres, R.4
Zarate, R.5
Ramirez, N.6
Abajo, A.7
Navarro, A.8
Moreno, I.9
Monzo, M.10
-
186
-
-
51049119231
-
Diagnostic and prognostic microRNAs in stage II colon cancer
-
Schepeler, T.; Reinert, J.T.; Ostenfeld, M.S.; Christensen, L.L.; Silahtaroglu, A.N.; Dyrskjot, L.; Wiuf, C.; Sorensen, F.J.; Kruhoffer, M.; Laurberg, S.; et al. Diagnostic and prognostic microRNAs in stage II colon cancer. Cancer Res. 2008, 68, 6416-6424.
-
(2008)
Cancer Res.
, vol.68
, pp. 6416-6424
-
-
Schepeler, T.1
Reinert, J.T.2
Ostenfeld, M.S.3
Christensen, L.L.4
Silahtaroglu, A.N.5
Dyrskjot, L.6
Wiuf, C.7
Sorensen, F.J.8
Kruhoffer, M.9
Laurberg, S.10
-
187
-
-
61349141809
-
Clinicopathological significance of microRNA-31,-143 and-145 expression in colorectal cancer
-
Wang, C.J.; Zhou, Z.G.; Wang, L.; Yang, L.; Zhou, B.; Gu, J.; Chen, H.Y.; Sun, X.F. Clinicopathological significance of microRNA-31,-143 and-145 expression in colorectal cancer. Dis. Markers 2009, 26, 27-34.
-
(2009)
Dis. Markers
, vol.26
, pp. 27-34
-
-
Wang, C.J.1
Zhou, Z.G.2
Wang, L.3
Yang, L.4
Zhou, B.5
Gu, J.6
Chen, H.Y.7
Sun, X.F.8
-
188
-
-
79959208404
-
Identification and functional analysis of epigenetically silenced microRNAs in colorectal cancer cells
-
Yan, H.; Choi, A.J.; Lee, B.H.; Ting, A.H. Identification and functional analysis of epigenetically silenced microRNAs in colorectal cancer cells. PLoS One 2011, 6, e20628.
-
(2011)
PLoS One
, vol.6
-
-
Yan, H.1
Choi, A.J.2
Lee, B.H.3
Ting, A.H.4
-
189
-
-
67649425233
-
Over-and under-expressed microRNAs in human colorectal cancer
-
Motoyama, K.; Inoue, H.; Takatsuno, Y.; Tanaka, F.; Mimori, K.; Uetake, H.; Sugihara, K.; Mori, M. Over-and under-expressed microRNAs in human colorectal cancer. Int. J. Oncol. 2009, 34, 1069-1075.
-
(2009)
Int. J. Oncol.
, vol.34
, pp. 1069-1075
-
-
Motoyama, K.1
Inoue, H.2
Takatsuno, Y.3
Tanaka, F.4
Mimori, K.5
Uetake, H.6
Sugihara, K.7
Mori, M.8
-
190
-
-
71549125896
-
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
-
Sarver, A.L.; French, A.J.; Borralho, P.M.; Thayanithy, V.; Oberg, A.L.; Silverstein, K.A.; Morlan, B.W.; Riska, S.M.; Boardman, L.A.; Cunningham, J.M.; et al. Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states. BMC Cancer 2009, 9, 401.
-
(2009)
BMC Cancer
, vol.9
, pp. 401
-
-
Sarver, A.L.1
French, A.J.2
Borralho, P.M.3
Thayanithy, V.4
Oberg, A.L.5
Silverstein, K.A.6
Morlan, B.W.7
Riska, S.M.8
Boardman, L.A.9
Cunningham, J.M.10
-
191
-
-
48649099908
-
Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer
-
Nagel, R.; le Sage, C.; Diosdado, B.; van der Waal, M.; Oude Vrielink, J.A.; Bolijn, A.; Meijer, G.A.; Agami, R. Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. Cancer Res. 2008, 68, 5795-5802.
-
(2008)
Cancer Res.
, vol.68
, pp. 5795-5802
-
-
Nagel, R.1
le Sage, C.2
Diosdado, B.3
van der Waal, M.4
Oude Vrielink, J.A.5
Bolijn, A.6
Meijer, G.A.7
Agami, R.8
-
192
-
-
70450260597
-
Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer
-
Arndt, G.M.; Dossey, L.; Cullen, L.M.; Lai, A.; Druker, R.; Eisbacher, M.; Zhang, C.; Tran, N.; Fan, H.; Retzlaff, K.; et al. Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer. BMC Cancer 2009, 9, 374.
-
(2009)
BMC Cancer
, vol.9
, pp. 374
-
-
Arndt, G.M.1
Dossey, L.2
Cullen, L.M.3
Lai, A.4
Druker, R.5
Eisbacher, M.6
Zhang, C.7
Tran, N.8
Fan, H.9
Retzlaff, K.10
-
193
-
-
49149128798
-
Overlapping expression of microRNAs in human embryonic colon and colorectal cancer
-
Monzo, M.; Navarro, A.; Bandres, E.; Artells, R.; Moreno, I.; Gel, B.; Ibeas, R.; Moreno, J.; Martinez, F.; Diaz, T.; et al. Overlapping expression of microRNAs in human embryonic colon and colorectal cancer. Cell Res. 2008, 18, 823-833.
-
(2008)
Cell Res.
, vol.18
, pp. 823-833
-
-
Monzo, M.1
Navarro, A.2
Bandres, E.3
Artells, R.4
Moreno, I.5
Gel, B.6
Ibeas, R.7
Moreno, J.8
Martinez, F.9
Diaz, T.10
-
194
-
-
79958270237
-
miRNA expression in colon polyps provides evidence for a multihit model of colon cancer
-
Oberg, A.L.; French, A.J.; Sarver, A.L.; Subramanian, S.; Morlan, B.W.; Riska, S.M.; Borralho, P.M.; Cunningham, J.M.; Boardman, L.A.; Wang, L.; et al. miRNA expression in colon polyps provides evidence for a multihit model of colon cancer. PLoS One 2011, 6, e20465.
-
(2011)
PLoS One
, vol.6
-
-
Oberg, A.L.1
French, A.J.2
Sarver, A.L.3
Subramanian, S.4
Morlan, B.W.5
Riska, S.M.6
Borralho, P.M.7
Cunningham, J.M.8
Boardman, L.A.9
Wang, L.10
-
195
-
-
77954368612
-
Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma
-
Earle, J.S.; Luthra, R.; Romans, A.; Abraham, R.; Ensor, J.; Yao, H.; Hamilton, S.R. Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma. J. Mol. Diagn. 2010, 12, 433-440.
-
(2010)
J. Mol. Diagn.
, vol.12
, pp. 433-440
-
-
Earle, J.S.1
Luthra, R.2
Romans, A.3
Abraham, R.4
Ensor, J.5
Yao, H.6
Hamilton, S.R.7
-
196
-
-
79954455860
-
Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas
-
Vogt, M.; Munding, J.; Gruner, M.; Liffers, S.T.; Verdoodt, B.; Hauk, J.; Steinstraesser, L.; Tannapfel, A.; Hermeking, H. Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. Virchows Arch. 2011, 458, 313-322.
-
(2011)
Virchows Arch.
, vol.458
, pp. 313-322
-
-
Vogt, M.1
Munding, J.2
Gruner, M.3
Liffers, S.T.4
Verdoodt, B.5
Hauk, J.6
Steinstraesser, L.7
Tannapfel, A.8
Hermeking, H.9
-
197
-
-
81155158414
-
Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients
-
Stratmann, J.; Wang, C.J.; Gnosa, S.; Wallin, A.; Hinselwood, D.; Sun, X.F.; Zhang, H. Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients. BMC Cancer 2011, 11, 345.
-
(2011)
BMC Cancer
, vol.11
, pp. 345
-
-
Stratmann, J.1
Wang, C.J.2
Gnosa, S.3
Wallin, A.4
Hinselwood, D.5
Sun, X.F.6
Zhang, H.7
-
198
-
-
79952752337
-
Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis
-
Cheng, H.; Zhang, L.; Cogdell, D.E.; Zheng, H.; Schetter, A.J.; Nykter, M.; Harris, C.C.; Chen, K.; Hamilton, S.R.; Zhang, W. Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis. PLoS One 2011, 6, e17745.
-
(2011)
PLoS One
, vol.6
-
-
Cheng, H.1
Zhang, L.2
Cogdell, D.E.3
Zheng, H.4
Schetter, A.J.5
Nykter, M.6
Harris, C.C.7
Chen, K.8
Hamilton, S.R.9
Zhang, W.10
-
199
-
-
0037115392
-
Dependence of histone modifications and gene expression on DNA hypermethylation in cancer
-
Fahrner, J.A.; Eguchi, S.; Herman, J.G.; Baylin, S.B. Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. Cancer Res. 2002, 62, 7213-7218.
-
(2002)
Cancer Res.
, vol.62
, pp. 7213-7218
-
-
Fahrner, J.A.1
Eguchi, S.2
Herman, J.G.3
Baylin, S.B.4
-
200
-
-
71049136170
-
MicroRNAs in colorectal cancer: Translation of molecular biology into clinical application
-
Slaby, O.; Svoboda, M.; Michalek, J.; Vyzula, R. MicroRNAs in colorectal cancer: Translation of molecular biology into clinical application. Mol. Cancer 2009, 8, 102.
-
(2009)
Mol. Cancer
, vol.8
, pp. 102
-
-
Slaby, O.1
Svoboda, M.2
Michalek, J.3
Vyzula, R.4
-
201
-
-
41649093940
-
The methylator phenotype in microsatellite stable colorectal cancers is characterized by a distinct gene expression profile
-
Ferracin, M.; Gafa, R.; Miotto, E.; Veronese, A.; Pultrone, C.; Sabbioni, S.; Lanza, G.; Negrini, M. The methylator phenotype in microsatellite stable colorectal cancers is characterized by a distinct gene expression profile. J. Pathol. 2008, 214, 594-602.
-
(2008)
J. Pathol.
, vol.214
, pp. 594-602
-
-
Ferracin, M.1
Gafa, R.2
Miotto, E.3
Veronese, A.4
Pultrone, C.5
Sabbioni, S.6
Lanza, G.7
Negrini, M.8
-
202
-
-
84868451906
-
SPARC and DNA methylation: Possible diagnostic and therapeutic implications in gastrointestinal cancers
-
Nagaraju, G.P.; El-Rayes, B.F. SPARC and DNA methylation: Possible diagnostic and therapeutic implications in gastrointestinal cancers. Cancer Lett. 2013, 328, 10-17.
-
(2013)
Cancer Lett.
, vol.328
, pp. 10-17
-
-
Nagaraju, G.P.1
El-Rayes, B.F.2
-
203
-
-
20444461133
-
Genome-wide expression analysis of therapy-resistant tumors reveals SPARC as a novel target for cancer therapy
-
Tai, I.T.; Dai, M.; Owen, D.A.; Chen, L.B. Genome-wide expression analysis of therapy-resistant tumors reveals SPARC as a novel target for cancer therapy. J. Clin. Invest. 2005, 115, 1492-1502.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1492-1502
-
-
Tai, I.T.1
Dai, M.2
Owen, D.A.3
Chen, L.B.4
-
204
-
-
55949136282
-
SPARC in cancer biology: Its role in cancer progression and potential for therapy
-
Tai, I.T.; Tang, M.J. SPARC in cancer biology: Its role in cancer progression and potential for therapy. Drug Resist. Updat. 2008, 11, 231-246.
-
(2008)
Drug Resist. Updat.
, vol.11
, pp. 231-246
-
-
Tai, I.T.1
Tang, M.J.2
-
205
-
-
80054084433
-
Epigenetics and chemoresistance in colorectal cancer: An opportunity for treatment tailoring and novel therapeutic strategies
-
Crea, F.; Nobili, S.; Paolicchi, E.; Perrone, G.; Napoli, C.; Landini, I.; Danesi, R.; Mini, E. Epigenetics and chemoresistance in colorectal cancer: An opportunity for treatment tailoring and novel therapeutic strategies. Drug Resist. Updat. 2011, 14, 280-296.
-
(2011)
Drug Resist. Updat.
, vol.14
, pp. 280-296
-
-
Crea, F.1
Nobili, S.2
Paolicchi, E.3
Perrone, G.4
Napoli, C.5
Landini, I.6
Danesi, R.7
Mini, E.8
-
206
-
-
30644474460
-
Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9
-
Greiner, D.; Bonaldi, T.; Eskeland, R.; Roemer, E.; Imhof, A. Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. Nat. Chem. Biol. 2005, 1, 143-145.
-
(2005)
Nat. Chem. Biol.
, vol.1
, pp. 143-145
-
-
Greiner, D.1
Bonaldi, T.2
Eskeland, R.3
Roemer, E.4
Imhof, A.5
-
207
-
-
33846783261
-
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase
-
Kubicek, S.; O'Sullivan, R.J.; August, E.M.; Hickey, E.R.; Zhang, Q.; Teodoro, M.L.; Rea, S.; Mechtler, K.; Kowalski, J.A.; Homon, C.A.; et al. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol. Cell 2007, 25, 473-481.
-
(2007)
Mol. Cell
, vol.25
, pp. 473-481
-
-
Kubicek, S.1
O'Sullivan, R.J.2
August, E.M.3
Hickey, E.R.4
Zhang, Q.5
Teodoro, M.L.6
Rea, S.7
Mechtler, K.8
Kowalski, J.A.9
Homon, C.A.10
-
208
-
-
79960493567
-
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
-
Vedadi, M.; Barsyte-Lovejoy, D.; Liu, F.; Rival-Gervier, S.; Allali-Hassani, A.; Labrie, V.; Wigle, T.J.; Dimaggio, P.A.; Wasney, G.A.; Siarheyeva, A.; Dong, A.; et al. A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat. Chem. Biol. 2011, 7, 566-574.
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 566-574
-
-
Vedadi, M.1
Barsyte-Lovejoy, D.2
Liu, F.3
Rival-Gervier, S.4
Allali-Hassani, A.5
Labrie, V.6
Wigle, T.J.7
Dimaggio, P.A.8
Wasney, G.A.9
Siarheyeva, A.10
Dong, A.11
-
209
-
-
79960058024
-
Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor
-
Daigle, S.R.; Olhava, E.J.; Therkelsen, C.A.; Majer, C.R.; Sneeringer, C.J.; Song, J.; Johnston, L.D.; Scott, M.P.; Smith, J.J.; Xiao, Y.; et al. Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor. Cancer Cell 2011, 20, 53-65.
-
(2011)
Cancer Cell
, vol.20
, pp. 53-65
-
-
Daigle, S.R.1
Olhava, E.J.2
Therkelsen, C.A.3
Majer, C.R.4
Sneeringer, C.J.5
Song, J.6
Johnston, L.D.7
Scott, M.P.8
Smith, J.J.9
Xiao, Y.10
-
210
-
-
80052473151
-
Structural basis of substrate methylation and inhibition of SMYD2
-
Ferguson, A.D.; Larsen, N.A.; Howard, T.; Pollard, H.; Green, I.; Grande, C.; Cheung, T.; Garcia-Arenas, R.; Cowen, S.; Wu, J.; et al. Structural basis of substrate methylation and inhibition of SMYD2. Structure 2011, 19, 1262-1273.
-
(2011)
Structure
, vol.19
, pp. 1262-1273
-
-
Ferguson, A.D.1
Larsen, N.A.2
Howard, T.3
Pollard, H.4
Green, I.5
Grande, C.6
Cheung, T.7
Garcia-Arenas, R.8
Cowen, S.9
Wu, J.10
-
211
-
-
62049083789
-
Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294
-
Chang, Y.; Zhang, X.; Horton, J.R.; Upadhyay, A.K.; Spannhoff, A.; Liu, J.; Snyder, J.P.; Bedford, M.T.; Cheng, X. Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294. Nat. Struct. Mol. Biol. 2009, 16, 312-317.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 312-317
-
-
Chang, Y.1
Zhang, X.2
Horton, J.R.3
Upadhyay, A.K.4
Spannhoff, A.5
Liu, J.6
Snyder, J.P.7
Bedford, M.T.8
Cheng, X.9
-
212
-
-
84862681781
-
Epigenetic drug discovery: Targeting DNA methyltransferases
-
Foulks, J.M.; Parnell, K.M.; Nix, R.N.; Chau, S.; Swierczek, K.; Saunders, M.; Wright, K.; Hendrickson, T.F.; Ho, K.K.; McCullar, M.V.; et al. Epigenetic drug discovery: Targeting DNA methyltransferases. J. Biomol. Screen. 2012, 17, 2-17.
-
(2012)
J. Biomol. Screen.
, vol.17
, pp. 2-17
-
-
Foulks, J.M.1
Parnell, K.M.2
Nix, R.N.3
Chau, S.4
Swierczek, K.5
Saunders, M.6
Wright, K.7
Hendrickson, T.F.8
Ho, K.K.9
McCullar, M.V.10
-
213
-
-
84863497603
-
A dynamic multi-compartmental model of DNA methylation with demonstrable predictive value in hematological malignancies
-
McGovern, A.P.; Powell, B.E.; Chevassut, T.J. A dynamic multi-compartmental model of DNA methylation with demonstrable predictive value in hematological malignancies. J. Theor. Biol. 2012, 310, 14-20.
-
(2012)
J. Theor. Biol.
, vol.310
, pp. 14-20
-
-
McGovern, A.P.1
Powell, B.E.2
Chevassut, T.J.3
-
214
-
-
65249157050
-
Epigenetics, DNA methylation, and chromatin modifying drugs
-
Szyf, M. Epigenetics, DNA methylation, and chromatin modifying drugs. Annu. Rev. Pharmacol. Toxicol. 2009, 49, 243-263.
-
(2009)
Annu. Rev. Pharmacol. Toxicol.
, vol.49
, pp. 243-263
-
-
Szyf, M.1
-
215
-
-
0023375843
-
Azacitidine: 10 years later
-
Glover, A.B.; Leyland-Jones, B.R.; Chun, H.G.; Davies, B.; Hoth, D.F. Azacitidine: 10 years later. Cancer Treat. Rep. 1987, 71, 737-746.
-
(1987)
Cancer Treat. Rep.
, vol.71
, pp. 737-746
-
-
Glover, A.B.1
Leyland-Jones, B.R.2
Chun, H.G.3
Davies, B.4
Hoth, D.F.5
-
216
-
-
84655163371
-
Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer
-
Juergens, R.A.; Wrangle, J.; Vendetti, F.P.; Murphy, S.C.; Zhao, M.; Coleman, B.; Sebree, R.; Rodgers, K.; Hooker, C.M.; Franco, N.; et al. Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. Cancer Discov. 2011, 1, 598-607.
-
(2011)
Cancer Discov.
, vol.1
, pp. 598-607
-
-
Juergens, R.A.1
Wrangle, J.2
Vendetti, F.P.3
Murphy, S.C.4
Zhao, M.5
Coleman, B.6
Sebree, R.7
Rodgers, K.8
Hooker, C.M.9
Franco, N.10
-
217
-
-
66249127951
-
A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation
-
Datta, J.; Ghoshal, K.; Denny, W.A.; Gamage, S.A.; Brooke, D.G.; Phiasivongsa, P.; Redkar, S.; Jacob, S.T. A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation. Cancer Res. 2009, 69, 4277-4285.
-
(2009)
Cancer Res.
, vol.69
, pp. 4277-4285
-
-
Datta, J.1
Ghoshal, K.2
Denny, W.A.3
Gamage, S.A.4
Brooke, D.G.5
Phiasivongsa, P.6
Redkar, S.7
Jacob, S.T.8
-
218
-
-
31544441371
-
Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols
-
Lee, W.J.; Zhu, B.T. Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols. Carcinogenesis 2006, 27, 269-277.
-
(2006)
Carcinogenesis
, vol.27
, pp. 269-277
-
-
Lee, W.J.1
Zhu, B.T.2
-
219
-
-
25144507259
-
Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
-
Lee, W.J.; Shim, J.Y.; Zhu, B.T. Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids. Mol. Pharmacol. 2005, 68, 1018-1030.
-
(2005)
Mol. Pharmacol.
, vol.68
, pp. 1018-1030
-
-
Lee, W.J.1
Shim, J.Y.2
Zhu, B.T.3
-
220
-
-
84874537453
-
Curcumin modulates DNA methylation in colorectal cancer cells
-
Link, A.; Balaguer, F.; Shen, Y.; Lozano, J.J.; Leung, H.C.; Boland, C.R.; Goel, A. Curcumin modulates DNA methylation in colorectal cancer cells. PLoS One 2013, 8, e57709.
-
(2013)
PLoS One
, vol.8
-
-
Link, A.1
Balaguer, F.2
Shen, Y.3
Lozano, J.J.4
Leung, H.C.5
Boland, C.R.6
Goel, A.7
-
221
-
-
33845969839
-
Dietary polyphenols may affect DNA methylation
-
Fang, M.; Chen, D.; Yang, C.S. Dietary polyphenols may affect DNA methylation. J. Nutr. 2007, 137, 223S-228S.
-
(2007)
J. Nutr.
, vol.137
-
-
Fang, M.1
Chen, D.2
Yang, C.S.3
-
222
-
-
79952972082
-
New drug therapies in peripheral T-cell lymphoma
-
Howman, R.A.; Prince, H.M. New drug therapies in peripheral T-cell lymphoma. Expert Rev. Anticancer Ther. 2011, 11, 457-472.
-
(2011)
Expert Rev. Anticancer Ther.
, vol.11
, pp. 457-472
-
-
Howman, R.A.1
Prince, H.M.2
-
223
-
-
77955474688
-
Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells
-
Park, M.A.; Reinehr, R.; Haussinger, D.; Voelkel-Johnson, C.; Ogretmen, B.; Yacoub, A.; Grant, S.; Dent, P. Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells. Mol. Cancer Ther. 2010, 9, 2220-2231.
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 2220-2231
-
-
Park, M.A.1
Reinehr, R.2
Haussinger, D.3
Voelkel-Johnson, C.4
Ogretmen, B.5
Yacoub, A.6
Grant, S.7
Dent, P.8
-
224
-
-
53549119055
-
Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation
-
Park, M.A.; Zhang, G.; Martin, A.P.; Hamed, H.; Mitchell, C.; Hylemon, P.B.; Graf, M.; Rahmani, M.; Ryan, K.; Liu, X.; et al. Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. Cancer Biol. Ther. 2008, 7, 1648-1662.
-
(2008)
Cancer Biol. Ther.
, vol.7
, pp. 1648-1662
-
-
Park, M.A.1
Zhang, G.2
Martin, A.P.3
Hamed, H.4
Mitchell, C.5
Hylemon, P.B.6
Graf, M.7
Rahmani, M.8
Ryan, K.9
Liu, X.10
-
225
-
-
70349780606
-
The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors
-
Spannhoff, A.; Hauser, A.T.; Heinke, R.; Sippl, W.; Jung, M. The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors. Chem. Med. Chem. 2009, 4, 1568-1582.
-
(2009)
Chem. Med. Chem.
, vol.4
, pp. 1568-1582
-
-
Spannhoff, A.1
Hauser, A.T.2
Heinke, R.3
Sippl, W.4
Jung, M.5
-
226
-
-
84871674660
-
Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells
-
Benoit, Y.D.; Laursen, K.B.; Witherspoon, M.S.; Lipkin, S.M.; Gudas, L.J. Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells. J. Cell Physiol. 2013, 228, 764-772.
-
(2013)
J. Cell Physiol.
, vol.228
, pp. 764-772
-
-
Benoit, Y.D.1
Laursen, K.B.2
Witherspoon, M.S.3
Lipkin, S.M.4
Gudas, L.J.5
-
227
-
-
50249095068
-
Early phase II trial of oral vorinostat in relapsed or refractory breast, colorectal, or non-small cell lung cancer
-
Vansteenkiste, J.; van Cutsem, E.; Dumez, H.; Chen, C.; Ricker, J.L.; Randolph, S.S.; Schoffski, P. Early phase II trial of oral vorinostat in relapsed or refractory breast, colorectal, or non-small cell lung cancer. Invest. New Drugs 2008, 26, 483-488.
-
(2008)
Invest. New Drugs
, vol.26
, pp. 483-488
-
-
Vansteenkiste, J.1
van Cutsem, E.2
Dumez, H.3
Chen, C.4
Ricker, J.L.5
Randolph, S.S.6
Schoffski, P.7
-
228
-
-
84860327244
-
Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to fas ligand-induced apoptosis in vitro and tumor suppression in vivo
-
Yang, D.; Torres, C.M.; Bardhan, K.; Zimmerman, M.; McGaha, T.L.; Liu, K. Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to fas ligand-induced apoptosis in vitro and tumor suppression in vivo. J. Immunol. 2012, 188, 4441-4449.
-
(2012)
J. Immunol.
, vol.188
, pp. 4441-4449
-
-
Yang, D.1
Torres, C.M.2
Bardhan, K.3
Zimmerman, M.4
McGaha, T.L.5
Liu, K.6
-
229
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D.; Weinberg, R.A. The hallmarks of cancer. Cell 2000, 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
230
-
-
17644419708
-
Impaired CD95 expression predisposes for recurrence in curatively resected colon carcinoma: Clinical evidence for immunoselection and CD95L mediated control of minimal residual disease
-
Strater, J.; Hinz, U.; Hasel, C.; Bhanot, U.; Mechtersheimer, G.; Lehnert, T.; Moller, P. Impaired CD95 expression predisposes for recurrence in curatively resected colon carcinoma: Clinical evidence for immunoselection and CD95L mediated control of minimal residual disease. Gut 2005, 54, 661-665.
-
(2005)
Gut
, vol.54
, pp. 661-665
-
-
Strater, J.1
Hinz, U.2
Hasel, C.3
Bhanot, U.4
Mechtersheimer, G.5
Lehnert, T.6
Moller, P.7
-
231
-
-
0032476609
-
Fas and Fas ligand interactions suppress melanoma lung metastasis
-
Owen-Schaub, L.B.; van Golen, K.L.; Hill, L.L.; Price, J.E. Fas and Fas ligand interactions suppress melanoma lung metastasis. J. Exp. Med. 1998, 188, 1717-1723.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1717-1723
-
-
Owen-Schaub, L.B.1
van Golen, K.L.2
Hill, L.L.3
Price, J.E.4
-
232
-
-
0028246885
-
Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium
-
Moller, P.; Koretz, K.; Leithauser, F.; Bruderlein, S.; Henne, C.; Quentmeier, A.; Krammer, P.H. Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium. Int. J. Cancer 1994, 57, 371-377.
-
(1994)
Int. J. Cancer
, vol.57
, pp. 371-377
-
-
Moller, P.1
Koretz, K.2
Leithauser, F.3
Bruderlein, S.4
Henne, C.5
Quentmeier, A.6
Krammer, P.H.7
-
233
-
-
34249868241
-
Adoptive T cell therapy for cancer in the clinic
-
June, C.H. Adoptive T cell therapy for cancer in the clinic. J. Clin. Invest. 2007, 117, 1466-1476.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1466-1476
-
-
June, C.H.1
-
234
-
-
84858758766
-
Adoptive immunotherapy for cancer: Harnessing the T cell response
-
Restifo, N.P.; Dudley, M.E.; Rosenberg, S.A. Adoptive immunotherapy for cancer: Harnessing the T cell response. Nat. Rev. Immunol. 2012, 12, 269-281.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 269-281
-
-
Restifo, N.P.1
Dudley, M.E.2
Rosenberg, S.A.3
-
235
-
-
79953059789
-
Natural innate and adaptive immunity to cancer
-
Vesely, M.D.; Kershaw, M.H.; Schreiber, R.D.; Smyth, M.J. Natural innate and adaptive immunity to cancer. Annu. Rev. Immunol. 2011, 29, 235-271.
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 235-271
-
-
Vesely, M.D.1
Kershaw, M.H.2
Schreiber, R.D.3
Smyth, M.J.4
-
236
-
-
59149100185
-
IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression
-
Yang, D.; Wang, S.; Brooks, C.; Dong, Z.; Schoenlein, P.V.; Kumar, V.; Ouyang, X.; Xiong, H.; Lahat, G.; Hayes-Jordan, A.; et al. IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression. Cancer Res. 2009, 69, 1080-1088.
-
(2009)
Cancer Res.
, vol.69
, pp. 1080-1088
-
-
Yang, D.1
Wang, S.2
Brooks, C.3
Dong, Z.4
Schoenlein, P.V.5
Kumar, V.6
Ouyang, X.7
Xiong, H.8
Lahat, G.9
Hayes-Jordan, A.10
-
237
-
-
34548863369
-
Targeting lymphotoxin beta receptor with tumor-specific T lymphocytes for tumor regression
-
Yang, D.; Ud Din, N.; Browning, D.D.; Abrams, S.I.; Liu, K. Targeting lymphotoxin beta receptor with tumor-specific T lymphocytes for tumor regression. Clin. Cancer Res. 2007, 13, 5202-5210.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 5202-5210
-
-
Yang, D.1
Ud Din, N.2
Browning, D.D.3
Abrams, S.I.4
Liu, K.5
-
238
-
-
18744408483
-
The histone-deacetylase inhibitor SAHA potentiates proapoptotic effects of 5-fluorouracil and irinotecan in hepatoma cells
-
Ocker, M.; Alajati, A.; Ganslmayer, M.; Zopf, S.; Luders, M.; Neureiter, D.; Hahn, E.G.; Schuppan, D.; Herold, C. The histone-deacetylase inhibitor SAHA potentiates proapoptotic effects of 5-fluorouracil and irinotecan in hepatoma cells. J. Cancer Res. Clin. Oncol. 2005, 131, 385-394.
-
(2005)
J. Cancer Res. Clin. Oncol.
, vol.131
, pp. 385-394
-
-
Ocker, M.1
Alajati, A.2
Ganslmayer, M.3
Zopf, S.4
Luders, M.5
Neureiter, D.6
Hahn, E.G.7
Schuppan, D.8
Herold, C.9
-
239
-
-
0037869289
-
Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines
-
Arnold, C.N.; Goel, A.; Boland, C.R. Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines. Int. J. Cancer 2003, 106, 66-73.
-
(2003)
Int. J. Cancer
, vol.106
, pp. 66-73
-
-
Arnold, C.N.1
Goel, A.2
Boland, C.R.3
-
240
-
-
0038387494
-
5-fluorouracil: Mechanisms of action and clinical strategies
-
Longley, D.B.; Harkin, D.P.; Johnston, P.G. 5-fluorouracil: Mechanisms of action and clinical strategies. Nat. Rev. Cancer 2003, 3, 330-338.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
241
-
-
0019277437
-
Facilitated transport of uracil and 5-fluorouracil, and permeation of orotic acid into cultured mammalian cells
-
Wohlhueter, R.M.; McIvor, R.S.; Plagemann, P.G. Facilitated transport of uracil and 5-fluorouracil, and permeation of orotic acid into cultured mammalian cells. J. Cell Physiol. 1980, 104, 309-319.
-
(1980)
J. Cell Physiol.
, vol.104
, pp. 309-319
-
-
Wohlhueter, R.M.1
McIvor, R.S.2
Plagemann, P.G.3
-
242
-
-
4143083857
-
5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers
-
Noordhuis, P.; Holwerda, U.; van der Wilt, C.L.; van Groeningen, C.J.; Smid, K.; Meijer, S.; Pinedo, H.M.; Peters, G.J. 5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers. Ann. Oncol. 2004, 15, 1025-1032.
-
(2004)
Ann. Oncol.
, vol.15
, pp. 1025-1032
-
-
Noordhuis, P.1
Holwerda, U.2
van der Wilt, C.L.3
van Groeningen, C.J.4
Smid, K.5
Meijer, S.6
Pinedo, H.M.7
Peters, G.J.8
-
243
-
-
66849132243
-
Decreased levels of UMP kinase as a mechanism of fluoropyrimidine resistance
-
Humeniuk, R.; Menon, L.G.; Mishra, P.J.; Gorlick, R.; Sowers, R.; Rode, W.; Pizzorno, G.; Cheng, Y.C.; Kemeny, N.; Bertino, J.R.; et al. Decreased levels of UMP kinase as a mechanism of fluoropyrimidine resistance. Mol. Cancer Ther. 2009, 8, 1037-1044.
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 1037-1044
-
-
Humeniuk, R.1
Menon, L.G.2
Mishra, P.J.3
Gorlick, R.4
Sowers, R.5
Rode, W.6
Pizzorno, G.7
Cheng, Y.C.8
Kemeny, N.9
Bertino, J.R.10
-
244
-
-
0033783056
-
Mechanism of action of fluoropyrimidines: Relevance to the new developments in colorectal cancer chemotherapy
-
Sobrero, A.; Guglielmi, A.; Grossi, F.; Puglisi, F.; Aschele, C. Mechanism of action of fluoropyrimidines: Relevance to the new developments in colorectal cancer chemotherapy. Semin. Oncol. 2000, 27, 72-77.
-
(2000)
Semin. Oncol.
, vol.27
, pp. 72-77
-
-
Sobrero, A.1
Guglielmi, A.2
Grossi, F.3
Puglisi, F.4
Aschele, C.5
-
245
-
-
0015993325
-
Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides
-
Danenberg, P.V.; Langenbach, R.J.; Heidelberger, C. Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides. Biochemistry 1974, 13, 926-933.
-
(1974)
Biochemistry
, vol.13
, pp. 926-933
-
-
Danenberg, P.V.1
Langenbach, R.J.2
Heidelberger, C.3
-
246
-
-
0015962412
-
Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate
-
Santi, D.V.; McHenry, C.S.; Sommer, H. Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. Biochemistry 1974, 13, 471-481.
-
(1974)
Biochemistry
, vol.13
, pp. 471-481
-
-
Santi, D.V.1
McHenry, C.S.2
Sommer, H.3
-
247
-
-
0022626114
-
Binding of 5-fluorodeoxyuridylate to thymidylate synthase in human colon adenocarcinoma xenografts
-
Houghton, J.A.; Torrance, P.M.; Radparvar, S.; Williams, L.G.; Houghton, P.J. Binding of 5-fluorodeoxyuridylate to thymidylate synthase in human colon adenocarcinoma xenografts. Eur. J. Cancer Clin. Oncol. 1986, 22, 505-510.
-
(1986)
Eur. J. Cancer Clin. Oncol.
, vol.22
, pp. 505-510
-
-
Houghton, J.A.1
Torrance, P.M.2
Radparvar, S.3
Williams, L.G.4
Houghton, P.J.5
-
248
-
-
0028982818
-
Ratio of 2'-deoxyadenosine-5'-triphosphate/thymidine-5'-triphosphate influences the commitment of human colon carcinoma cells to thymineless death
-
Houghton, J.A.; Tillman, D.M.; Harwood, F.G. Ratio of 2'-deoxyadenosine-5'-triphosphate/thymidine-5'-triphosphate influences the commitment of human colon carcinoma cells to thymineless death. Clin. Cancer Res. 1995, 1, 723-730.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 723-730
-
-
Houghton, J.A.1
Tillman, D.M.2
Harwood, F.G.3
-
249
-
-
0023655202
-
Deoxyribonucleoside triphosphate imbalance. 5-Fluorodeoxyuridine-induced DNA double strand breaks in mouse FM3A cells and the mechanism of cell death
-
Yoshioka, A.; Tanaka, S.; Hiraoka, O.; Koyama, Y.; Hirota, Y.; Ayusawa, D.; Seno, T.; Garrett, C.; Wataya, Y. Deoxyribonucleoside triphosphate imbalance. 5-Fluorodeoxyuridine-induced DNA double strand breaks in mouse FM3A cells and the mechanism of cell death. J. Biol. Chem. 1987, 262, 8235-8241.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 8235-8241
-
-
Yoshioka, A.1
Tanaka, S.2
Hiraoka, O.3
Koyama, Y.4
Hirota, Y.5
Ayusawa, D.6
Seno, T.7
Garrett, C.8
Wataya, Y.9
-
250
-
-
12144290775
-
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients
-
Wang, T.L.; Diaz, L.A., Jr.; Romans, K.; Bardelli, A.; Saha, S.; Galizia, G.; Choti, M.; Donehower, R.; Parmigiani, G.; Shih Ie, M.; et al. Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients. Proc. Natl. Acad. Sci. USA 2004, 101, 3089-3094.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3089-3094
-
-
Wang, T.L.1
Diaz Jr., L.A.2
Romans, K.3
Bardelli, A.4
Saha, S.5
Galizia, G.6
Choti, M.7
Donehower, R.8
Parmigiani, G.9
Shih Ie, M.10
-
251
-
-
55449094139
-
Copy-number analysis of topoisomerase and thymidylate synthase genes in frozen and FFPE DNAs of colorectal cancers
-
Yu, J.; Miller, R.; Zhang, W.; Sharma, M.; Holtschlag, V.; Watson, M.A.; McLeod, H.L. Copy-number analysis of topoisomerase and thymidylate synthase genes in frozen and FFPE DNAs of colorectal cancers. Pharmacogenomics 2008, 9, 1459-1466.
-
(2008)
Pharmacogenomics
, vol.9
, pp. 1459-1466
-
-
Yu, J.1
Miller, R.2
Zhang, W.3
Sharma, M.4
Holtschlag, V.5
Watson, M.A.6
McLeod, H.L.7
-
252
-
-
78649591408
-
Amplification of thymidylate synthetase in metastatic colorectal cancer patients pretreated with 5-fluorouracil-based chemotherapy
-
Watson, R.G.; Muhale, F.; Thorne, L.B.; Yu, J.; O'Neil, B.H.; Hoskins, J.M.; Meyers, M.O.; Deal, A.M.; Ibrahim, J.G.; Hudson, M.L.; et al. Amplification of thymidylate synthetase in metastatic colorectal cancer patients pretreated with 5-fluorouracil-based chemotherapy. Eur. J. Cancer 2010, 46, 3358-3364.
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 3358-3364
-
-
Watson, R.G.1
Muhale, F.2
Thorne, L.B.3
Yu, J.4
O'Neil, B.H.5
Hoskins, J.M.6
Meyers, M.O.7
Deal, A.M.8
Ibrahim, J.G.9
Hudson, M.L.10
-
253
-
-
33750317308
-
Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: A model for patient classification to aid fluoropyrimidine therapy
-
Brody, J.R.; Hucl, T.; Gallmeier, E.; Winter, J.M.; Kern, S.E.; Murphy, K.M. Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: A model for patient classification to aid fluoropyrimidine therapy. Cancer Res. 2006, 66, 9369-9373.
-
(2006)
Cancer Res.
, vol.66
, pp. 9369-9373
-
-
Brody, J.R.1
Hucl, T.2
Gallmeier, E.3
Winter, J.M.4
Kern, S.E.5
Murphy, K.M.6
-
254
-
-
33847611097
-
Involvement of gene polymorphisms of thymidylate synthase in gene expression, protein activity and anticancer drug cytotoxicity using the NCI-60 panel
-
Nief, N.; Le Morvan, V.; Robert, J. Involvement of gene polymorphisms of thymidylate synthase in gene expression, protein activity and anticancer drug cytotoxicity using the NCI-60 panel. Eur. J. Cancer 2007, 43, 955-962.
-
(2007)
Eur. J. Cancer
, vol.43
, pp. 955-962
-
-
Nief, N.1
Le Morvan, V.2
Robert, J.3
-
255
-
-
0034192487
-
Levels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylate synthase
-
Banerjee, D.; Gorlick, R.; Liefshitz, A.; Danenberg, K.; Danenberg, P.C.; Danenberg, P.V.; Klimstra, D.; Jhanwar, S.; Cordon-Cardo, C.; Fong, Y.; et al. Levels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylate synthase. Cancer Res. 2000, 60, 2365-2367.
-
(2000)
Cancer Res.
, vol.60
, pp. 2365-2367
-
-
Banerjee, D.1
Gorlick, R.2
Liefshitz, A.3
Danenberg, K.4
Danenberg, P.C.5
Danenberg, P.V.6
Klimstra, D.7
Jhanwar, S.8
Cordon-Cardo, C.9
Fong, Y.10
-
256
-
-
69149099584
-
Identification of genes conferring resistance to 5-fluorouracil
-
Yoo, B.K.; Gredler, R.; Vozhilla, N.; Su, Z.Z.; Chen, D.; Forcier, T.; Shah, K.; Saxena, U.; Hansen, U.; Fisher, P.B.; et al. Identification of genes conferring resistance to 5-fluorouracil. Proc. Natl. Acad. Sci. USA 2009, 106, 12938-12943.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12938-12943
-
-
Yoo, B.K.1
Gredler, R.2
Vozhilla, N.3
Su, Z.Z.4
Chen, D.5
Forcier, T.6
Shah, K.7
Saxena, U.8
Hansen, U.9
Fisher, P.B.10
-
257
-
-
65849197551
-
The chromatin remodeling factor CHD8 interacts with elongating RNA polymerase II and controls expression of the cyclin E2 gene
-
Rodriguez-Paredes, M.; Ceballos-Chavez, M.; Esteller, M.; Garcia-Dominguez, M.; Reyes, J.C. The chromatin remodeling factor CHD8 interacts with elongating RNA polymerase II and controls expression of the cyclin E2 gene. Nucleic Acids Res. 2009, 37, 2449-2460.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 2449-2460
-
-
Rodriguez-Paredes, M.1
Ceballos-Chavez, M.2
Esteller, M.3
Garcia-Dominguez, M.4
Reyes, J.C.5
-
258
-
-
44049101802
-
Identification of predictive biomarkers for the histone deacetylase inhibitor belinostat in a panel of human cancer cell lines
-
Dejligbjerg, M.; Grauslund, M.; Christensen, I.J.; Tjornelund, J.; Buhl Jensen, P.; Sehested, M. Identification of predictive biomarkers for the histone deacetylase inhibitor belinostat in a panel of human cancer cell lines. Cancer Biomark. 2008, 4, 101-109.
-
(2008)
Cancer Biomark.
, vol.4
, pp. 101-109
-
-
Dejligbjerg, M.1
Grauslund, M.2
Christensen, I.J.3
Tjornelund, J.4
Buhl Jensen, P.5
Sehested, M.6
-
259
-
-
66849111560
-
Epigenetic reversal of acquired resistance to 5-fluorouracil treatment
-
Humeniuk, R.; Mishra, P.J.; Bertino, J.R.; Banerjee, D. Epigenetic reversal of acquired resistance to 5-fluorouracil treatment. Mol. Cancer Ther. 2009, 8, 1045-1054.
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 1045-1054
-
-
Humeniuk, R.1
Mishra, P.J.2
Bertino, J.R.3
Banerjee, D.4
-
260
-
-
0038409001
-
Reaction of human UMP-CMP kinase with natural and analog substrates
-
Pasti, C.; Gallois-Montbrun, S.; Munier-Lehmann, H.; Veron, M.; Gilles, A.M.; Deville-Bonne, D. Reaction of human UMP-CMP kinase with natural and analog substrates. Eur. J. Biochem. 2003, 270, 1784-1790.
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 1784-1790
-
-
Pasti, C.1
Gallois-Montbrun, S.2
Munier-Lehmann, H.3
Veron, M.4
Gilles, A.M.5
Deville-Bonne, D.6
-
261
-
-
44349137412
-
SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response
-
Cheetham, S.; Tang, M.J.; Mesak, F.; Kennecke, H.; Owen, D.; Tai, I.T. SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response. Br. J. Cancer 2008, 98, 1810-1819.
-
(2008)
Br. J. Cancer
, vol.98
, pp. 1810-1819
-
-
Cheetham, S.1
Tang, M.J.2
Mesak, F.3
Kennecke, H.4
Owen, D.5
Tai, I.T.6
-
262
-
-
80155131161
-
Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3
-
Liu, F.; Liu, Q.; Yang, D.; Bollag, W.B.; Robertson, K.; Wu, P.; Liu, K. Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3. Cancer Res. 2011, 71, 6807-6816.
-
(2011)
Cancer Res.
, vol.71
, pp. 6807-6816
-
-
Liu, F.1
Liu, Q.2
Yang, D.3
Bollag, W.B.4
Robertson, K.5
Wu, P.6
Liu, K.7
-
263
-
-
78651350836
-
Methylation of BNIP3 and DAPK indicates lower response to chemotherapy and poor prognosis in gastric cancer
-
Sugita, H.; Iida, S.; Inokuchi, M.; Kato, K.; Ishiguro, M.; Ishikawa, T.; Takagi, Y.; Enjoji, M.; Yamada, H.; Uetake, H.; Kojima, K.; Sugihara, K. Methylation of BNIP3 and DAPK indicates lower response to chemotherapy and poor prognosis in gastric cancer. Oncol. Rep. 2011, 25, 513-518.
-
(2011)
Oncol. Rep.
, vol.25
, pp. 513-518
-
-
Sugita, H.1
Iida, S.2
Inokuchi, M.3
Kato, K.4
Ishiguro, M.5
Ishikawa, T.6
Takagi, Y.7
Enjoji, M.8
Yamada, H.9
Uetake, H.10
Kojima, K.11
Sugihara, K.12
-
264
-
-
84873033322
-
Chemotherapy and Radiotherapy Downregulate the Activity and Expression of DNA Methyltransferase and Enhance Bcl-2/E1B-19-kDa Interacting Protein-3-Induced Apoptosis in Human Colorectal Cancer Cells
-
Deng, Q.; Huang, C.M.; Chen, N.; Li, L.; Wang, X.D.; Zhang, W.; Bi, F.; Tang, Q.L.; Li, Z.P.; Wang, W. Chemotherapy and Radiotherapy Downregulate the Activity and Expression of DNA Methyltransferase and Enhance Bcl-2/E1B-19-kDa Interacting Protein-3-Induced Apoptosis in Human Colorectal Cancer Cells. Chemotherapy 2012, 58, 445-453.
-
(2012)
Chemotherapy
, vol.58
, pp. 445-453
-
-
Deng, Q.1
Huang, C.M.2
Chen, N.3
Li, L.4
Wang, X.D.5
Zhang, W.6
Bi, F.7
Tang, Q.L.8
Li, Z.P.9
Wang, W.10
-
265
-
-
68149172699
-
Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed
-
Di Gennaro, E.; Bruzzese, F.; Pepe, S.; Leone, A.; Delrio, P.; Subbarayan, P.R.; Avallone, A.; Budillon, A. Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed. Cancer Biol. Ther. 2009, 8, 782-791.
-
(2009)
Cancer Biol. Ther.
, vol.8
, pp. 782-791
-
-
di Gennaro, E.1
Bruzzese, F.2
Pepe, S.3
Leone, A.4
Delrio, P.5
Subbarayan, P.R.6
Avallone, A.7
Budillon, A.8
-
266
-
-
80052576073
-
Gene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancer
-
Claerhout, S.; Lim, J.Y.; Choi, W.; Park, Y.Y.; Kim, K.; Kim, S.B.; Lee, J.S.; Mills, G.B.; Cho, J.Y. Gene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancer. PLoS One 2011, 6, e24662.
-
(2011)
PLoS One
, vol.6
-
-
Claerhout, S.1
Lim, J.Y.2
Choi, W.3
Park, Y.Y.4
Kim, K.5
Kim, S.B.6
Lee, J.S.7
Mills, G.B.8
Cho, J.Y.9
-
267
-
-
33846257239
-
Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells
-
Lee, J.H.; Park, J.H.; Jung, Y.; Kim, J.H.; Jong, H.S.; Kim, T.Y.; Bang, Y.J. Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells. Mol. Cancer Ther. 2006, 5, 3085-3095.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 3085-3095
-
-
Lee, J.H.1
Park, J.H.2
Jung, Y.3
Kim, J.H.4
Jong, H.S.5
Kim, T.Y.6
Bang, Y.J.7
-
268
-
-
34248399662
-
The histone deacetylase inhibitor PXD101 synergises with 5-fluorouracil to inhibit colon cancer cell growth in vitro and in vivo
-
Tumber, A.; Collins, L.S.; Petersen, K.D.; Thougaard, A.; Christiansen, S.J.; Dejligbjerg, M.; Jensen, P.B.; Sehested, M.; Ritchie, J.W. The histone deacetylase inhibitor PXD101 synergises with 5-fluorouracil to inhibit colon cancer cell growth in vitro and in vivo. Cancer Chemother. Pharmacol. 2007, 60, 275-283.
-
(2007)
Cancer Chemother. Pharmacol.
, vol.60
, pp. 275-283
-
-
Tumber, A.1
Collins, L.S.2
Petersen, K.D.3
Thougaard, A.4
Christiansen, S.J.5
Dejligbjerg, M.6
Jensen, P.B.7
Sehested, M.8
Ritchie, J.W.9
-
269
-
-
67449089565
-
Histone deacetylase inhibitors suppress thymidylate synthase gene expression and synergize with the fluoropyrimidines in colon cancer cells
-
Fazzone, W.; Wilson, P.M.; Labonte, M.J.; Lenz, H.J.; Ladner, R.D. Histone deacetylase inhibitors suppress thymidylate synthase gene expression and synergize with the fluoropyrimidines in colon cancer cells. Int. J. Cancer 2009, 125, 463-473.
-
(2009)
Int. J. Cancer
, vol.125
, pp. 463-473
-
-
Fazzone, W.1
Wilson, P.M.2
Labonte, M.J.3
Lenz, H.J.4
Ladner, R.D.5
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