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Volumn 1, Issue DEC, 2014, Pages

Atypical hemolytic uremic syndrome post-kidney transplantation: Two case reports and review of the literature

Author keywords

aHUS; Eculizumab; Genetic mutation; Kidney transplant; Recurrence

Indexed keywords


EID: 84947130293     PISSN: None     EISSN: 2296858X     Source Type: Journal    
DOI: 10.3389/fmed.2014.00052     Document Type: Review
Times cited : (27)

References (112)
  • 1
    • 70350279315 scopus 로고    scopus 로고
    • Atypical hemolytic-uremic syndrome
    • Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med (2009) 361:1676-87. doi: 10.1056/NEJMra0902814
    • (2009) N Engl J Med , vol.361 , pp. 1676-1687
    • Noris, M.1    Remuzzi, G.2
  • 2
    • 84898645797 scopus 로고    scopus 로고
    • Update on hemolytic uremic syndrome: diagnostic and therapeutic recommendations
    • Salvadori M, Bertoni E. Update on hemolytic uremic syndrome: diagnostic and therapeutic recommendations. World J Nephrol (2013) 2:56-76. doi:10.5527/wjn.v2.i3.56
    • (2013) World J Nephrol , vol.2 , pp. 56-76
    • Salvadori, M.1    Bertoni, E.2
  • 3
    • 0020662906 scopus 로고
    • Escherichia coli O157:H7 strains associated with haemorrhagic colitis in the United States produce a Shigella dysenteriae 1 (SHIGA) like cytotoxin
    • O'Brien AO, Lively TA, Chen ME, Rothman SW, Formal SB. Escherichia coli O157:H7 strains associated with haemorrhagic colitis in the United States produce a Shigella dysenteriae 1 (SHIGA) like cytotoxin. Lancet (1983) 1(8326 Pt 1):702. doi:10.1016/S0140-6736(83)91987-6
    • (1983) Lancet , vol.1 , Issue.8326 , pp. 702
    • O'Brien, A.O.1    Lively, T.A.2    Chen, M.E.3    Rothman, S.W.4    Formal, S.B.5
  • 5
    • 84884821706 scopus 로고    scopus 로고
    • Targeted strategies in the prevention and management of atypical HUS recurrence after kidney transplantation
    • Zuber J, Le Quintrec M, Morris H, Frémeaux-Bacchi V, Loirat C, Legendre C. Targeted strategies in the prevention and management of atypical HUS recurrence after kidney transplantation. Transplant Rev (Orlando) (2013) 27:117-25. doi:10.1016/j.trre.2013.07.003
    • (2013) Transplant Rev (Orlando) , vol.27 , pp. 117-125
    • Zuber, J.1    Le Quintrec, M.2    Morris, H.3    Frémeaux-Bacchi, V.4    Loirat, C.5    Legendre, C.6
  • 6
    • 0015937612 scopus 로고
    • Letter: plasma-C3 in haemolytic-uraemic syndrome and thrombotic thrombocytopenic purpura
    • Cameron JS, Vick R. Letter: plasma-C3 in haemolytic-uraemic syndrome and thrombotic thrombocytopenic purpura. Lancet (1973) 2:975. doi:10.1016/S0140-6736(73)92645-7
    • (1973) Lancet , vol.2 , pp. 975
    • Cameron, J.S.1    Vick, R.2
  • 9
    • 84875382274 scopus 로고    scopus 로고
    • Complement disorders and hemolytic uremic syndrome
    • Joseph C, Gattineni J. Complement disorders and hemolytic uremic syndrome. Curr Opin Pediatr (2013) 25:209-15. doi:10.1097/MOP.0b013e32835df48a
    • (2013) Curr Opin Pediatr , vol.25 , pp. 209-215
    • Joseph, C.1    Gattineni, J.2
  • 11
    • 54049137505 scopus 로고    scopus 로고
    • Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome
    • Frémeaux-Bacchi V, Miller EC, Liszewski MK, Strain L, Blouin J, Brown AL, et al. Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome. Blood (2008) 112:4948-52. doi:10.1182/blood-2008-01-133702
    • (2008) Blood , vol.112 , pp. 4948-4952
    • Frémeaux-Bacchi, V.1    Miller, E.C.2    Liszewski, M.K.3    Strain, L.4    Blouin, J.5    Brown, A.L.6
  • 13
    • 17744376183 scopus 로고    scopus 로고
    • Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32
    • Esparza-Gordillo J, Goicoechea de Jorge E, Buil A, Carreras Berges L, López-Trascasa M, Sánchez-Corral P, et al. Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32. Hum Mol Genet (2005) 14:703-12. doi:10.1093/hmg/ddi099
    • (2005) Hum Mol Genet , vol.14 , pp. 703-712
    • Esparza-Gordillo, J.1    Goicoechea de Jorge, E.2    Buil, A.3    Carreras Berges, L.4    López-Trascasa, M.5    Sánchez-Corral, P.6
  • 14
    • 33644964155 scopus 로고    scopus 로고
    • Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree
    • Esparza-Gordillo J, Jorge EG, Garrido CA, Carreras L, López-Trascasa M, Sánchez-Corral P, et al. Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree. Mol Immunol (2006) 43:1769-75. doi:10.1016/j.molimm.2005.11.008
    • (2006) Mol Immunol , vol.43 , pp. 1769-1775
    • Esparza-Gordillo, J.1    Jorge, E.G.2    Garrido, C.A.3    Carreras, L.4    López-Trascasa, M.5    Sánchez-Corral, P.6
  • 15
    • 26944480588 scopus 로고    scopus 로고
    • The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts
    • Fremeaux-Bacchi V, Kemp EJ, Goodship JA, Dragon-Durey MA, Strain L, Loirat C, et al. The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts. J Med Genet (2005) 42:852-6. doi:10.1136/jmg.2005.030783
    • (2005) J Med Genet , vol.42 , pp. 852-856
    • Fremeaux-Bacchi, V.1    Kemp, E.J.2    Goodship, J.A.3    Dragon-Durey, M.A.4    Strain, L.5    Loirat, C.6
  • 16
    • 84949117415 scopus 로고    scopus 로고
    • New functional and structural insights from updated mutational databases for complement factor H, factor I, membrane cofactor protein and C3
    • Rodriguez E, Rallapalli PM, Osborne AJ, Perkins SJ. New functional and structural insights from updated mutational databases for complement factor H, factor I, membrane cofactor protein and C3. Biosci Rep (2014) 34(5):e00146. doi:10.1042/BSR20140117
    • (2014) Biosci Rep , vol.34 , Issue.5
    • Rodriguez, E.1    Rallapalli, P.M.2    Osborne, A.J.3    Perkins, S.J.4
  • 17
    • 33747159590 scopus 로고    scopus 로고
    • Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome
    • Caprioli J, Noris M, Brioschi S, Pianetti G, Castelletti F, Bettinaglio P, et al. Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome. Blood (2006) 108:1267-79. doi:10.1182/blood-2005-10-007252
    • (2006) Blood , vol.108 , pp. 1267-1279
    • Caprioli, J.1    Noris, M.2    Brioschi, S.3    Pianetti, G.4    Castelletti, F.5    Bettinaglio, P.6
  • 18
    • 0035143299 scopus 로고    scopus 로고
    • The molecular basis of familial hemolytic uremic syndrome: mutation analysis of factor H gene reveals a hot spot in short consensus repeat 20
    • Caprioli J, Bettinaglio P, Zipfel PF, Amadei B, Daina E, Gamba S, et al. The molecular basis of familial hemolytic uremic syndrome: mutation analysis of factor H gene reveals a hot spot in short consensus repeat 20. J Am Soc Nephrol (2001) 12:297-307
    • (2001) J Am Soc Nephrol , vol.12 , pp. 297-307
    • Caprioli, J.1    Bettinaglio, P.2    Zipfel, P.F.3    Amadei, B.4    Daina, E.5    Gamba, S.6
  • 19
    • 77958587405 scopus 로고    scopus 로고
    • Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype
    • Noris M, Caprioli J, Bresin E, Mossali C, Pianetti G, Gamba S, et al. Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype. Clin J Am Soc Nephrol (2010) 5:1844-59. doi:10.2215/CJN.02210310
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 1844-1859
    • Noris, M.1    Caprioli, J.2    Bresin, E.3    Mossali, C.4    Pianetti, G.5    Gamba, S.6
  • 20
    • 27744452766 scopus 로고    scopus 로고
    • Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome
    • Kavanagh D, Kemp EJ, Mayland E, Winney RJ, Duffield JS, Warwick G, et al. Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome. J Am Soc Nephrol (2005) 16:2150-5. doi:10.1681/ASN.2005010103
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2150-2155
    • Kavanagh, D.1    Kemp, E.J.2    Mayland, E.3    Winney, R.J.4    Duffield, J.S.5    Warwick, G.6
  • 21
    • 34548309310 scopus 로고    scopus 로고
    • Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome
    • Kavanagh D, Richards A, Noris M, Hauhart R, Liszewski MK, Karpman D, et al. Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome. Mol Immunol (2008) 45:95-105. doi:10.1016/j.molimm.2007.05.004
    • (2008) Mol Immunol , vol.45 , pp. 95-105
    • Kavanagh, D.1    Richards, A.2    Noris, M.3    Hauhart, R.4    Liszewski, M.K.5    Karpman, D.6
  • 22
    • 75649133611 scopus 로고    scopus 로고
    • Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome
    • Moore I, Strain L, Pappworth I, Kavanagh D, Barlow PN, Herbert AP, et al. Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome. Blood (2010) 115:379-87. doi:10.1182/blood-2009-05-221549
    • (2010) Blood , vol.115 , pp. 379-387
    • Moore, I.1    Strain, L.2    Pappworth, I.3    Kavanagh, D.4    Barlow, P.N.5    Herbert, A.P.6
  • 23
    • 84875029270 scopus 로고    scopus 로고
    • Complement factor H-related protein 1 deficiency and factor H antibodies in pediatric patients with atypical hemolytic uremic syndrome
    • Hofer J, Janecke AR, Zimmerhackl LB, Riedl M, Rosales A, Giner T, et al. Complement factor H-related protein 1 deficiency and factor H antibodies in pediatric patients with atypical hemolytic uremic syndrome. Clin J Am Soc Nephrol (2013) 8:407-15. doi:10.2215/CJN.01260212
    • (2013) Clin J Am Soc Nephrol , vol.8 , pp. 407-415
    • Hofer, J.1    Janecke, A.R.2    Zimmerhackl, L.B.3    Riedl, M.4    Rosales, A.5    Giner, T.6
  • 24
    • 34547633064 scopus 로고    scopus 로고
    • Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome
    • Sellier-Leclerc AL, Fremeaux-Bacchi V, Dragon-Durey MA, Macher MA, Niaudet P, Guest G, et al. Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome. J Am Soc Nephrol (2007) 18:2392-400. doi:10.1681/ASN.2006080811
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2392-2400
    • Sellier-Leclerc, A.L.1    Fremeaux-Bacchi, V.2    Dragon-Durey, M.A.3    Macher, M.A.4    Niaudet, P.5    Guest, G.6
  • 25
    • 0242331610 scopus 로고    scopus 로고
    • Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome
    • Richards A, Kemp EJ, Liszewski MK, Goodship JA, Lampe AK, Decorte R, et al. Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome. Proc Natl Acad Sci U S A (2003) 100:12966-71. doi:10.1073/pnas.2135497100
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12966-12971
    • Richards, A.1    Kemp, E.J.2    Liszewski, M.K.3    Goodship, J.A.4    Lampe, A.K.5    Decorte, R.6
  • 26
    • 75749153964 scopus 로고    scopus 로고
    • Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome
    • Bienaime F, Dragon-Durey MA, Regnier CH, Nilsson SC, Kwan WH, Blouin J, et al. Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome. Kidney Int (2010) 77:339-49. doi:10.1038/ki.2009.472
    • (2010) Kidney Int , vol.77 , pp. 339-349
    • Bienaime, F.1    Dragon-Durey, M.A.2    Regnier, C.H.3    Nilsson, S.C.4    Kwan, W.H.5    Blouin, J.6
  • 27
    • 85061974325 scopus 로고    scopus 로고
    • In: Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong C-T, et al. editors. GeneReviews® [Internet]. Seattle, WA: University of Washington; 1993-2014
    • Noris M, Bresin E, Mele C, Remuzzi G. Atypical hemolytic-uremic syndrome. In: Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong C-T, et al. editors. GeneReviews® [Internet]. Seattle, WA: University of Washington; 1993-2014 (2013). p. 9-26
    • (2013) Atypical hemolytic-uremic syndrome , pp. 9-26
    • Noris, M.1    Bresin, E.2    Mele, C.3    Remuzzi, G.4
  • 28
    • 74249114451 scopus 로고    scopus 로고
    • Mutations in complement factor I as found in atypical hemolytic uremic syndrome lead to either altered secretion or altered function of factor I
    • Nilsson SC, Kalchishkova N, Trouw LA, Fremeaux-Bacchi V, Villoutreix BO, Blom AM. Mutations in complement factor I as found in atypical hemolytic uremic syndrome lead to either altered secretion or altered function of factor I. Eur J Immunol (2010) 40:172-85. doi:10.1002/eji.200939280
    • (2010) Eur J Immunol , vol.40 , pp. 172-185
    • Nilsson, S.C.1    Kalchishkova, N.2    Trouw, L.A.3    Fremeaux-Bacchi, V.4    Villoutreix, B.O.5    Blom, A.M.6
  • 29
    • 84886949690 scopus 로고    scopus 로고
    • Post-transplant recurrence of atypical hemolytic uremic syndrome in a patient with thrombomodulin mutation
    • Sinibaldi S, Guzzo I, Piras R, Bresin E, Emma F, Dello Strologo L. Post-transplant recurrence of atypical hemolytic uremic syndrome in a patient with thrombomodulin mutation. Pediatr Transplant (2013) 17:E177-81. doi:10.1111/petr.12151
    • (2013) Pediatr Transplant , vol.17 , pp. E177-E181
    • Sinibaldi, S.1    Guzzo, I.2    Piras, R.3    Bresin, E.4    Emma, F.5    Dello Strologo, L.6
  • 30
    • 77951257162 scopus 로고    scopus 로고
    • A novel mutation in the complement factor B gene (CFB) and atypical hemolytic uremic syndrome
    • Tawadrous H, Maga T, Sharma J, Kupferman J, Smith RJ, Schoeneman M. A novel mutation in the complement factor B gene (CFB) and atypical hemolytic uremic syndrome. Pediatr Nephrol (2010) 25:947-51. doi:10.1007/s00467-009-1415-3
    • (2010) Pediatr Nephrol , vol.25 , pp. 947-951
    • Tawadrous, H.1    Maga, T.2    Sharma, J.3    Kupferman, J.4    Smith, R.J.5    Schoeneman, M.6
  • 31
    • 80052565757 scopus 로고    scopus 로고
    • Atypical hemolytic uremic syndrome
    • Loirat C, Fremeaux-Bacchi V. Atypical hemolytic uremic syndrome. Orphanet J Rare Dis (2011) 6:60. doi:10.1186/1750-1172-6-60
    • (2011) Orphanet J Rare Dis , vol.6 , pp. 60
    • Loirat, C.1    Fremeaux-Bacchi, V.2
  • 32
    • 53749084348 scopus 로고    scopus 로고
    • Complement and the atypical hemolytic uremic syndrome in children
    • Loirat C, Noris M, Fremeaux-Bacchi V. Complement and the atypical hemolytic uremic syndrome in children. Pediatr Nephrol (2008) 23:1957-72. doi:10.1007/s00467-008-0872-4
    • (2008) Pediatr Nephrol , vol.23 , pp. 1957-1972
    • Loirat, C.1    Noris, M.2    Fremeaux-Bacchi, V.3
  • 33
    • 77952682366 scopus 로고    scopus 로고
    • Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome
    • Maga TK, Nishimura CJ, Weaver AE, Frees KL, Smith RJ. Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome. Hum Mutat (2010) 31:E1445-60. doi:10.1002/humu.21256
    • (2010) Hum Mutat , vol.31 , pp. E1445-E1460
    • Maga, T.K.1    Nishimura, C.J.2    Weaver, A.E.3    Frees, K.L.4    Smith, R.J.5
  • 35
    • 76949087440 scopus 로고    scopus 로고
    • Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome
    • Abarrategui-Garrido C, Martínez-Barricarte R, López-Trascasa M, de Córdoba SR, Sánchez-Corral P. Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome. Blood (2009) 114:4261-71. doi:10.1182/blood-2009-05-223834
    • (2009) Blood , vol.114 , pp. 4261-4271
    • Abarrategui-Garrido, C.1    Martínez-Barricarte, R.2    López-Trascasa, M.3    de Córdoba, S.R.4    Sánchez-Corral, P.5
  • 36
    • 57649230771 scopus 로고    scopus 로고
    • Complement factor H related proteins in immune diseases
    • Skerka C, Zipfel PF. Complement factor H related proteins in immune diseases. Vaccine (2008) 26(Suppl 8):I9-14. doi:10.1016/j.vaccine.2008.11.021
    • (2008) Vaccine , vol.26 , pp. I9-I14
    • Skerka, C.1    Zipfel, P.F.2
  • 37
    • 33750855444 scopus 로고    scopus 로고
    • Atypical haemolytic uraemic syndrome associated with a hybrid complement gene
    • Venables JP, Strain L, Routledge D, Bourn D, Powell HM, Warwicker P, et al. Atypical haemolytic uraemic syndrome associated with a hybrid complement gene. PLoS Med (2006) 3:e431. doi:10.1371/journal.pmed.0030431
    • (2006) PLoS Med , vol.3
    • Venables, J.P.1    Strain, L.2    Routledge, D.3    Bourn, D.4    Powell, H.M.5    Warwicker, P.6
  • 38
    • 84855862414 scopus 로고    scopus 로고
    • A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome
    • Francis NJ, McNicholas B, Awan A, Waldron M, Reddan D, Sadlier D, et al. A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome. Blood (2012) 119:591-601. doi:10.1182/blood-2011-03-339903
    • (2012) Blood , vol.119 , pp. 591-601
    • Francis, N.J.1    McNicholas, B.2    Awan, A.3    Waldron, M.4    Reddan, D.5    Sadlier, D.6
  • 39
    • 38949155911 scopus 로고    scopus 로고
    • Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency
    • Józsi M, Licht C, Strobel S, Zipfel SL, Richter H, Heinen S, et al. Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency. Blood (2008) 111:1512-4. doi:10.1182/blood-2007-09-109876
    • (2008) Blood , vol.111 , pp. 1512-1514
    • Józsi, M.1    Licht, C.2    Strobel, S.3    Zipfel, S.L.4    Richter, H.5    Heinen, S.6
  • 40
    • 67650508077 scopus 로고    scopus 로고
    • The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome
    • Dragon-Durey MA, Blanc C, Marliot F, Loirat C, Blouin J, Sautes-Fridman C, et al. The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome. J Med Genet (2009) 46:447-50. doi:10.1136/jmg.2008.064766
    • (2009) J Med Genet , vol.46 , pp. 447-450
    • Dragon-Durey, M.A.1    Blanc, C.2    Marliot, F.3    Loirat, C.4    Blouin, J.5    Sautes-Fridman, C.6
  • 41
    • 77956231486 scopus 로고    scopus 로고
    • DEAP-HUS: deficiency of CFHR plasma proteins and autoantibody-positive form of hemolytic uremic syndrome
    • Zipfel PF, Mache C, Müller D, Licht C, Wigger M, Skerka C, et al. DEAP-HUS: deficiency of CFHR plasma proteins and autoantibody-positive form of hemolytic uremic syndrome. Pediatr Nephrol (2010) 25:2009-19. doi:10.1007/s00467-010-1446-9
    • (2010) Pediatr Nephrol , vol.25 , pp. 2009-2019
    • Zipfel, P.F.1    Mache, C.2    Müller, D.3    Licht, C.4    Wigger, M.5    Skerka, C.6
  • 43
    • 0242694369 scopus 로고    scopus 로고
    • The risk of recurrence of hemolytic uremic syndrome after renal transplantation in children
    • Loirat C, Niaudet P. The risk of recurrence of hemolytic uremic syndrome after renal transplantation in children. Pediatr Nephrol (2003) 18:1095-101. doi:10.1007/s00467-003-1289-8
    • (2003) Pediatr Nephrol , vol.18 , pp. 1095-1101
    • Loirat, C.1    Niaudet, P.2
  • 44
    • 0026073049 scopus 로고
    • Post-transplantation outcome of patients with hemolytic-uremic syndrome: update
    • Hébert D, Kim EM, Sibley RK, Mauer MS. Post-transplantation outcome of patients with hemolytic-uremic syndrome: update. Pediatr Nephrol (1991) 5:162-7. doi:10.1007/BF00852876
    • (1991) Pediatr Nephrol , vol.5 , pp. 162-167
    • Hébert, D.1    Kim, E.M.2    Sibley, R.K.3    Mauer, M.S.4
  • 45
    • 0022621084 scopus 로고
    • Recurrence of hemolytic uremic syndrome in renal transplant recipients
    • Hebert D, Sibley RK, Mauer SM. Recurrence of hemolytic uremic syndrome in renal transplant recipients. Kidney Int Suppl (1986) 19:S51-8
    • (1986) Kidney Int Suppl , vol.19 , pp. S51-S58
    • Hebert, D.1    Sibley, R.K.2    Mauer, S.M.3
  • 46
    • 0141590417 scopus 로고    scopus 로고
    • Renal transplantation in patients with hemolytic uremic syndrome: high rate of recurrence and increased incidence of acute rejections
    • Artz MA, Steenbergen EJ, Hoitsma AJ, Monnens LA, Wetzels JF. Renal transplantation in patients with hemolytic uremic syndrome: high rate of recurrence and increased incidence of acute rejections. Transplantation (2003) 76:821-6. doi:10.1097/01.TP.0000085083.74065.1B
    • (2003) Transplantation , vol.76 , pp. 821-826
    • Artz, M.A.1    Steenbergen, E.J.2    Hoitsma, A.J.3    Monnens, L.A.4    Wetzels, J.F.5
  • 47
    • 0034034718 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome Recurrence after renal transplantation. Groupe Cooperatif de l'Ile-de-France (GCIF)
    • Lahlou A, Lang P, Charpentier B, Barrou B, Glotz D, Baron C, et al. Hemolytic uremic syndrome. Recurrence after renal transplantation. Groupe Cooperatif de l'Ile-de-France (GCIF). Medicine (Baltimore) (2000) 79:90-102. doi:10.1097/00005792-200003000-00003
    • (2000) Medicine (Baltimore) , vol.79 , pp. 90-102
    • Lahlou, A.1    Lang, P.2    Charpentier, B.3    Barrou, B.4    Glotz, D.5    Baron, C.6
  • 48
    • 0035959420 scopus 로고    scopus 로고
    • Recurrence of hemolytic uremic syndrome after renal transplantation in children: a report of the North American Pediatric Renal Transplant Cooperative Study
    • Quan A, Sullivan EK, Alexander SR. Recurrence of hemolytic uremic syndrome after renal transplantation in children: a report of the North American Pediatric Renal Transplant Cooperative Study. Transplantation (2001) 72:742-5. doi:10.1097/00007890-200108270-00033
    • (2001) Transplantation , vol.72 , pp. 742-745
    • Quan, A.1    Sullivan, E.K.2    Alexander, S.R.3
  • 49
    • 34548400755 scopus 로고    scopus 로고
    • Outcome of renal transplantation in patients with non-Shiga toxin-associated hemolytic uremic syndrome: prognostic significance of genetic background
    • Bresin E, Daina E, Noris M, Castelletti F, Stefanov R, Hill P, et al. Outcome of renal transplantation in patients with non-Shiga toxin-associated hemolytic uremic syndrome: prognostic significance of genetic background. Clin J Am Soc Nephrol (2006) 1:88-99. doi:10.2215/CJN.00050505
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 88-99
    • Bresin, E.1    Daina, E.2    Noris, M.3    Castelletti, F.4    Stefanov, R.5    Hill, P.6
  • 50
    • 49349112382 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome recurrence after renal transplantation
    • Loirat C, Fremeaux-Bacchi V. Hemolytic uremic syndrome recurrence after renal transplantation. Pediatr Transplant (2008) 12:619-29. doi:10.1111/j.1399-3046.2008.00910.x
    • (2008) Pediatr Transplant , vol.12 , pp. 619-629
    • Loirat, C.1    Fremeaux-Bacchi, V.2
  • 51
    • 84874417661 scopus 로고    scopus 로고
    • Complement genes strongly predict recurrence and graft outcome in adult renal transplant recipients with atypical hemolytic and uremic syndrome
    • Le Quintrec M, Zuber J, Moulin B, Kamar N, Jablonski M, Lionet A, et al. Complement genes strongly predict recurrence and graft outcome in adult renal transplant recipients with atypical hemolytic and uremic syndrome. Am J Transplant (2013) 13:663-75. doi:10.1111/ajt.12077
    • (2013) Am J Transplant , vol.13 , pp. 663-675
    • Le Quintrec, M.1    Zuber, J.2    Moulin, B.3    Kamar, N.4    Jablonski, M.5    Lionet, A.6
  • 52
    • 44449165673 scopus 로고    scopus 로고
    • Successful pre-transplant management of a patient with anti-factor H autoantibodies-associated haemolytic uraemic syndrome
    • Kwon T, Dragon-Durey MA, Macher MA, Baudouin V, Maisin A, Peuchmaur M, et al. Successful pre-transplant management of a patient with anti-factor H autoantibodies-associated haemolytic uraemic syndrome. Nephrol Dial Transplant (2008) 23:2088-90. doi:10.1093/ndt/gfn063
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 2088-2090
    • Kwon, T.1    Dragon-Durey, M.A.2    Macher, M.A.3    Baudouin, V.4    Maisin, A.5    Peuchmaur, M.6
  • 53
    • 65249156546 scopus 로고    scopus 로고
    • Anti-Factor H autoantibodies in a fifth renal transplant recipient with atypical hemolytic and uremic syndrome
    • Le Quintrec M, Zuber J, Noel LH, Thervet E, Frémeaux-Bacchi V, Niaudet P, et al. Anti-Factor H autoantibodies in a fifth renal transplant recipient with atypical hemolytic and uremic syndrome. Am J Transplant (2009) 9:1223-9. doi:10.1111/j.1600-6143.2009.02586.x
    • (2009) Am J Transplant , vol.9 , pp. 1223-1229
    • Le Quintrec, M.1    Zuber, J.2    Noel, L.H.3    Thervet, E.4    Frémeaux-Bacchi, V.5    Niaudet, P.6
  • 54
    • 72549110489 scopus 로고    scopus 로고
    • Successful renal transplantation in factor H autoantibody associated HUS with CFHR1 and 3 deficiency and CFH variant G2850T
    • Waters AM, Pappworth I, Marchbank K, Bockenhauer D, Tullus K, Pickering MC, et al. Successful renal transplantation in factor H autoantibody associated HUS with CFHR1 and 3 deficiency and CFH variant G2850T. Am J Transplant (2010) 10:168-72. doi:10.1111/j.1600-6143.2009.02870.x
    • (2010) Am J Transplant , vol.10 , pp. 168-172
    • Waters, A.M.1    Pappworth, I.2    Marchbank, K.3    Bockenhauer, D.4    Tullus, K.5    Pickering, M.C.6
  • 56
    • 58249107188 scopus 로고    scopus 로고
    • Recurrent atypical hemolytic uremic syndrome associated with factor I mutation in a living related renal transplant recipient
    • Chan MR, Thomas CP, Torrealba JR, Djamali A, Fernandez LA, Nishimura CJ, et al. Recurrent atypical hemolytic uremic syndrome associated with factor I mutation in a living related renal transplant recipient. Am J Kidney Dis (2009) 53:321-6. doi:10.1053/j.ajkd.2008.06.027
    • (2009) Am J Kidney Dis , vol.53 , pp. 321-326
    • Chan, M.R.1    Thomas, C.P.2    Torrealba, J.R.3    Djamali, A.4    Fernandez, L.A.5    Nishimura, C.J.6
  • 57
    • 34248664063 scopus 로고    scopus 로고
    • A missense mutation in factor I (IF) predisposes to atypical haemolytic uraemic syndrome
    • Geelen J, van den Dries K, Roos A, van de Kar N, de Kat Angelino C, Klasen I, et al. A missense mutation in factor I (IF) predisposes to atypical haemolytic uraemic syndrome. Pediatr Nephrol (2007) 22:371-5. doi:10.1007/s00467-006-0320-2
    • (2007) Pediatr Nephrol , vol.22 , pp. 371-375
    • Geelen, J.1    van den Dries, K.2    Roos, A.3    van de Kar, N.4    de Kat Angelino, C.5    Klasen, I.6
  • 58
    • 33751536085 scopus 로고    scopus 로고
    • A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation
    • Nilsson SC, Karpman D, Vaziri-Sani F, Kristoffersson AC, Salomon R, Provot F, et al. A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation. Mol Immunol (2007) 44:1835-44. doi:10.1016/j.molimm.2006.10.005
    • (2007) Mol Immunol , vol.44 , pp. 1835-1844
    • Nilsson, S.C.1    Karpman, D.2    Vaziri-Sani, F.3    Kristoffersson, A.C.4    Salomon, R.5    Provot, F.6
  • 59
    • 68449088805 scopus 로고    scopus 로고
    • Prophylactic plasma exchange in CD46-associated atypical haemolytic uremic syndrome
    • Davin JC, Buter N, Groothoff J, van Wijk J, Bouts A, Strain L, et al. Prophylactic plasma exchange in CD46-associated atypical haemolytic uremic syndrome. Pediatr Nephrol (2009) 24:1757-60. doi:10.1007/s00467-009-1188-8
    • (2009) Pediatr Nephrol , vol.24 , pp. 1757-1760
    • Davin, J.C.1    Buter, N.2    Groothoff, J.3    van Wijk, J.4    Bouts, A.5    Strain, L.6
  • 60
    • 33745812440 scopus 로고    scopus 로고
    • Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome
    • Fremeaux-Bacchi V, Moulton EA, Kavanagh D, Dragon-Durey MA, Blouin J, Caudy A, et al. Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome. J Am Soc Nephrol (2006) 17:2017-25. doi:10.1681/ASN.2005101051
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2017-2025
    • Fremeaux-Bacchi, V.1    Moulton, E.A.2    Kavanagh, D.3    Dragon-Durey, M.A.4    Blouin, J.5    Caudy, A.6
  • 63
    • 0036284207 scopus 로고    scopus 로고
    • Local synthesis of complement component C3 regulates acute renal transplant rejection
    • Pratt JR, Basheer SA, Sacks SH. Local synthesis of complement component C3 regulates acute renal transplant rejection. Nat Med (2002) 8:582-7. doi:10.1038/nm0602-582
    • (2002) Nat Med , vol.8 , pp. 582-587
    • Pratt, J.R.1    Basheer, S.A.2    Sacks, S.H.3
  • 64
    • 33746897348 scopus 로고    scopus 로고
    • Preventing renal ischemia-reperfusion injury using small interfering RNA by targeting complement 3 gene
    • Zheng X, Feng B, Chen G, Zhang X, Li M, Sun H, et al. Preventing renal ischemia-reperfusion injury using small interfering RNA by targeting complement 3 gene. Am J Transplant (2006) 6:2099-108. doi:10.1111/j.1600-6143.2006.01427.x
    • (2006) Am J Transplant , vol.6 , pp. 2099-2108
    • Zheng, X.1    Feng, B.2    Chen, G.3    Zhang, X.4    Li, M.5    Sun, H.6
  • 65
    • 70350475255 scopus 로고    scopus 로고
    • Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome
    • Roumenina LT, Jablonski M, Hue C, Blouin J, Dimitrov JD, Dragon-Durey MA, et al. Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome. Blood (2009) 114:2837-45. doi:10.1182/blood-2009-01-197640
    • (2009) Blood , vol.114 , pp. 2837-2845
    • Roumenina, L.T.1    Jablonski, M.2    Hue, C.3    Blouin, J.4    Dimitrov, J.D.5    Dragon-Durey, M.A.6
  • 66
    • 84876044818 scopus 로고    scopus 로고
    • Genetics and outcome of atypical hemolytic uremic syndrome: a nationwide French series comparing children and adults
    • Fremeaux-Bacchi V, Fakhouri F, Garnier A, Bienaimé F, Dragon-Durey MA, Ngo S, et al. Genetics and outcome of atypical hemolytic uremic syndrome: a nationwide French series comparing children and adults. Clin J Am Soc Nephrol (2013) 8:554-62. doi:10.2215/CJN.04760512
    • (2013) Clin J Am Soc Nephrol , vol.8 , pp. 554-562
    • Fremeaux-Bacchi, V.1    Fakhouri, F.2    Garnier, A.3    Bienaimé, F.4    Dragon-Durey, M.A.5    Ngo, S.6
  • 68
    • 68049125195 scopus 로고    scopus 로고
    • Expression of complement components differs between kidney allografts from living and deceased donors
    • Naesens M, Li L, Ying L, Sansanwal P, Sigdel TK, Hsieh SC, et al. Expression of complement components differs between kidney allografts from living and deceased donors. J Am Soc Nephrol (2009) 20:1839-51. doi:10.1681/ASN.2008111145
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1839-1851
    • Naesens, M.1    Li, L.2    Ying, L.3    Sansanwal, P.4    Sigdel, T.K.5    Hsieh, S.C.6
  • 69
    • 84875701958 scopus 로고    scopus 로고
    • Complement mediated renal inflammation induced by donor brain death: role of renal C5a-C5aR interaction
    • van Werkhoven MB, Damman J, van Dijk MC, Daha MR, de Jong IJ, Leliveld A, et al. Complement mediated renal inflammation induced by donor brain death: role of renal C5a-C5aR interaction. Am J Transplant (2013) 13:875-82. doi:10.1111/ajt.12130
    • (2013) Am J Transplant , vol.13 , pp. 875-882
    • van Werkhoven, M.B.1    Damman, J.2    van Dijk, M.C.3    Daha, M.R.4    de Jong, I.J.5    Leliveld, A.6
  • 71
    • 11144290605 scopus 로고    scopus 로고
    • Posttransplantation cytomegalovirus-induced recurrence of atypical hemolytic uremic syndrome associated with a factor H mutation: successful treatment with intensive plasma exchanges and ganciclovir
    • Olie KH, Goodship TH, Verlaak R, Florquin S, Groothoff JW, Strain L, et al. Posttransplantation cytomegalovirus-induced recurrence of atypical hemolytic uremic syndrome associated with a factor H mutation: successful treatment with intensive plasma exchanges and ganciclovir. Am J Kidney Dis (2005) 45:e12-5. doi:10.1053/j.ajkd.2004.09.012
    • (2005) Am J Kidney Dis , vol.45 , pp. e12-e15
    • Olie, K.H.1    Goodship, T.H.2    Verlaak, R.3    Florquin, S.4    Groothoff, J.W.5    Strain, L.6
  • 72
    • 79954443076 scopus 로고    scopus 로고
    • Eculizumab induces long-term remission in recurrent post-transplant HUS associated with C3 gene mutation
    • Al-Akash SI, Almond PS, Savell VH Jr, Gharaybeh SI, Hogue C. Eculizumab induces long-term remission in recurrent post-transplant HUS associated with C3 gene mutation. Pediatr Nephrol (2011) 26:613-9. doi:10.1007/s00467-010-1708-6
    • (2011) Pediatr Nephrol , vol.26 , pp. 613-619
    • Al-Akash, S.I.1    Almond, P.S.2    Savell, V.H.3    Gharaybeh, S.I.4    Hogue, C.5
  • 74
    • 79953019720 scopus 로고    scopus 로고
    • Atypical hemolytic uremic syndrome associated with H1N1 influenza A virus infection
    • Trachtman H, Sethna C, Epstein R, D'Souza M, Rubin LG, Ginocchio CC. Atypical hemolytic uremic syndrome associated with H1N1 influenza A virus infection. Pediatr Nephrol (2011) 26:145-6. doi:10.1007/s00467-010-1636-5
    • (2011) Pediatr Nephrol , vol.26 , pp. 145-146
    • Trachtman, H.1    Sethna, C.2    Epstein, R.3    D'Souza, M.4    Rubin, L.G.5    Ginocchio, C.C.6
  • 75
    • 0034130092 scopus 로고    scopus 로고
    • Thrombotic microangiopathy associated with parvovirus B 19 infection after renal transplantation
    • Murer L, Zacchello G, Bianchi D, Dall'Amico R, Montini G, Andreetta B, et al. Thrombotic microangiopathy associated with parvovirus B 19 infection after renal transplantation. J Am Soc Nephrol (2000) 11:1132-7
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1132-1137
    • Murer, L.1    Zacchello, G.2    Bianchi, D.3    Dall'Amico, R.4    Montini, G.5    Andreetta, B.6
  • 77
    • 80052473232 scopus 로고    scopus 로고
    • Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome
    • Weitz M, Amon O, Bassler D, Koenigsrainer A, Nadalin S. Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome. Pediatr Nephrol (2011) 26:1325-9. doi:10.1007/s00467-011-1879-9
    • (2011) Pediatr Nephrol , vol.26 , pp. 1325-1329
    • Weitz, M.1    Amon, O.2    Bassler, D.3    Koenigsrainer, A.4    Nadalin, S.5
  • 78
    • 79958202220 scopus 로고    scopus 로고
    • Pre-emptive eculizumab and plasmapheresis for renal transplant in atypical hemolytic uremic syndrome
    • Nester C, Stewart Z, Myers D, Jetton J, Nair R, Reed A, et al. Pre-emptive eculizumab and plasmapheresis for renal transplant in atypical hemolytic uremic syndrome. Clin J Am Soc Nephrol (2011) 6:1488-94. doi:10.2215/CJN.10181110
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 1488-1494
    • Nester, C.1    Stewart, Z.2    Myers, D.3    Jetton, J.4    Nair, R.5    Reed, A.6
  • 79
    • 53749100296 scopus 로고    scopus 로고
    • Impact of immunosuppressive treatment on endothelial biomarkers after kidney transplantation
    • Al-Massarani G, Vacher-Coponat H, Paul P, Widemann A, Arnaud L, Loundou A, et al. Impact of immunosuppressive treatment on endothelial biomarkers after kidney transplantation. Am J Transplant (2008) 8:2360-7. doi:10.1111/j.1600-6143.2008.02399.x
    • (2008) Am J Transplant , vol.8 , pp. 2360-2367
    • Al-Massarani, G.1    Vacher-Coponat, H.2    Paul, P.3    Widemann, A.4    Arnaud, L.5    Loundou, A.6
  • 81
    • 34250166544 scopus 로고    scopus 로고
    • De novo thrombotic microangiopathy An underrated complication of renal transplantation
    • Ponticelli C. De novo thrombotic microangiopathy. An underrated complication of renal transplantation. Clin Nephrol (2007) 67:335-40. doi:10.5414/CNP67335
    • (2007) Clin Nephrol , vol.67 , pp. 335-340
    • Ponticelli, C.1
  • 82
    • 48349086641 scopus 로고    scopus 로고
    • Complement mutation-associated de novo thrombotic microangiopathy following kidney transplantation
    • Le Quintrec M, Lionet A, Kamar N, Karras A, Barbier S, Buchler M, et al. Complement mutation-associated de novo thrombotic microangiopathy following kidney transplantation. Am J Transplant (2008) 8:1694-701. doi:10.1111/j.1600-6143.2008.02297.x
    • (2008) Am J Transplant , vol.8 , pp. 1694-1701
    • Le Quintrec, M.1    Lionet, A.2    Kamar, N.3    Karras, A.4    Barbier, S.5    Buchler, M.6
  • 83
    • 0037308113 scopus 로고    scopus 로고
    • De novo thrombotic microangiopathy in renal transplant recipients: a comparison of hemolytic uremic syndrome with localized renal thrombotic microangiopathy
    • Schwimmer J, Nadasdy TA, Spitalnik PF, Kaplan KL, Zand MS. De novo thrombotic microangiopathy in renal transplant recipients: a comparison of hemolytic uremic syndrome with localized renal thrombotic microangiopathy. Am J Kidney Dis (2003) 41:471-9. doi:10.1053/ajkd.2003.50058
    • (2003) Am J Kidney Dis , vol.41 , pp. 471-479
    • Schwimmer, J.1    Nadasdy, T.A.2    Spitalnik, P.F.3    Kaplan, K.L.4    Zand, M.S.5
  • 84
    • 80054767700 scopus 로고    scopus 로고
    • Successful treatment of de novo posttransplant thrombotic microangiopathy with eculizumab
    • Wilson CH, Brown AL, White SA, Goodship TH, Sheerin NS, Manas DM. Successful treatment of de novo posttransplant thrombotic microangiopathy with eculizumab. Transplantation (2011) 92:e42-3. doi:10.1097/TP.0b013e318230c0bd
    • (2011) Transplantation , vol.92 , pp. e42-e43
    • Wilson, C.H.1    Brown, A.L.2    White, S.A.3    Goodship, T.H.4    Sheerin, N.S.5    Manas, D.M.6
  • 86
    • 77950805395 scopus 로고    scopus 로고
    • Cardiovascular manifestations in patients with thrombotic thrombocytopenic purpura: a single-center experience
    • Gandhi K, Aronow WS, Desai H, Amin H, Sharma M, Lai HM, et al. Cardiovascular manifestations in patients with thrombotic thrombocytopenic purpura: a single-center experience. Clin Cardiol (2010) 33:213-6. doi:10.1002/clc.20731
    • (2010) Clin Cardiol , vol.33 , pp. 213-216
    • Gandhi, K.1    Aronow, W.S.2    Desai, H.3    Amin, H.4    Sharma, M.5    Lai, H.M.6
  • 88
    • 84921945959 scopus 로고    scopus 로고
    • Atypical HUS associated with severe, unexpected antibody-mediated rejection post kidney transplant
    • Stevenson S, Mallett A, Oliver K, Hyland V, Hawley C, Malmanche T, et al. Atypical HUS associated with severe, unexpected antibody-mediated rejection post kidney transplant. Nephrology (Carlton) (2014) 19(Suppl 1):22-6. doi:10.1111/nep.12195
    • (2014) Nephrology (Carlton) , vol.19 , pp. 22-26
    • Stevenson, S.1    Mallett, A.2    Oliver, K.3    Hyland, V.4    Hawley, C.5    Malmanche, T.6
  • 89
    • 84865611225 scopus 로고    scopus 로고
    • Antibody mediated rejection associated with complement factor h-related protein 3/1 deficiency successfully treated with eculizumab
    • Noone D, Al-Matrafi J, Tinckam K, Zipfel PF, Herzenberg AM, Thorner PS, et al. Antibody mediated rejection associated with complement factor h-related protein 3/1 deficiency successfully treated with eculizumab. Am J Transplant (2012) 12:2546-53. doi:10.1111/j.1600-6143.2012.04124.x
    • (2012) Am J Transplant , vol.12 , pp. 2546-2553
    • Noone, D.1    Al-Matrafi, J.2    Tinckam, K.3    Zipfel, P.F.4    Herzenberg, A.M.5    Thorner, P.S.6
  • 90
    • 84867993256 scopus 로고    scopus 로고
    • Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies
    • Zuber J, Fakhouri F, Roumenina LT, Loirat C, Frémeaux-Bacchi V, French Study Group for aHUS/C3G. Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies. Nat Rev Nephrol (2012) 8:643-57. doi:10.1038/nrneph.2012.214
    • (2012) Nat Rev Nephrol , vol.8 , pp. 643-657
    • Zuber, J.1    Fakhouri, F.2    Roumenina, L.T.3    Loirat, C.4    Frémeaux-Bacchi, V.5
  • 91
    • 47749148096 scopus 로고    scopus 로고
    • Plasma therapy in atypical haemolytic uremic syndrome: lessons from a family with a factor H mutation
    • Davin JC, Strain L, Goodship TH. Plasma therapy in atypical haemolytic uremic syndrome: lessons from a family with a factor H mutation. Pediatr Nephrol (2008) 23:1517-21. doi:10.1007/s00467-008-0833-y
    • (2008) Pediatr Nephrol , vol.23 , pp. 1517-1521
    • Davin, J.C.1    Strain, L.2    Goodship, T.H.3
  • 92
    • 84857442742 scopus 로고    scopus 로고
    • Management of hemolytic uremic syndrome
    • Loirat C, Saland J, Bitzan M. Management of hemolytic uremic syndrome. Presse Med (2012) 41(3 Pt 2):e115-35. doi:10.1016/j.lpm.2011.11.013
    • (2012) Presse Med , vol.41 , Issue.3 , pp. e115-e135
    • Loirat, C.1    Saland, J.2    Bitzan, M.3
  • 93
    • 0037062233 scopus 로고    scopus 로고
    • Combined kidney and liver transplantation for familial haemolytic uraemic syndrome
    • Remuzzi G, Ruggenenti P, Codazzi D, Noris M, Caprioli J, Locatelli G, et al. Combined kidney and liver transplantation for familial haemolytic uraemic syndrome. Lancet (2002) 359:1671-2. doi:10.1016/S0140-6736(02)08560-4
    • (2002) Lancet , vol.359 , pp. 1671-1672
    • Remuzzi, G.1    Ruggenenti, P.2    Codazzi, D.3    Noris, M.4    Caprioli, J.5    Locatelli, G.6
  • 94
    • 20244377213 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome: a fatal outcome after kidney and liver transplantation performed to correct factor h gene mutation
    • Remuzzi G, Ruggenenti P, Colledan M, Gridelli B, Bertani A, Bettinaglio P, et al. Hemolytic uremic syndrome: a fatal outcome after kidney and liver transplantation performed to correct factor h gene mutation. Am J Transplant (2005) 5:1146-50. doi:10.1111/j.1600-6143.2005.00783.x
    • (2005) Am J Transplant , vol.5 , pp. 1146-1150
    • Remuzzi, G.1    Ruggenenti, P.2    Colledan, M.3    Gridelli, B.4    Bertani, A.5    Bettinaglio, P.6
  • 95
    • 84861130721 scopus 로고    scopus 로고
    • Hyaluronan regulation of vascular integrity
    • Lennon FE, Singleton PA. Hyaluronan regulation of vascular integrity. Am J Cardiovasc Dis (2011) 1:200-13
    • (2011) Am J Cardiovasc Dis , vol.1 , pp. 200-213
    • Lennon, F.E.1    Singleton, P.A.2
  • 96
    • 37349124206 scopus 로고    scopus 로고
    • Shedding of the endothelial glycocalyx in patients undergoing major vascular surgery with global and regional ischemia
    • Rehm M, Bruegger D, Christ F, Conzen P, Thiel M, Jacob M, et al. Shedding of the endothelial glycocalyx in patients undergoing major vascular surgery with global and regional ischemia. Circulation (2007) 116:1896-906. doi:10.1161/CIRCULATIONAHA.106.684852
    • (2007) Circulation , vol.116 , pp. 1896-1906
    • Rehm, M.1    Bruegger, D.2    Christ, F.3    Conzen, P.4    Thiel, M.5    Jacob, M.6
  • 97
    • 84894107600 scopus 로고    scopus 로고
    • Liver-kidney transplantation to cure atypical HUS: still an option post-eculizumab?
    • Saland J. Liver-kidney transplantation to cure atypical HUS: still an option post-eculizumab? Pediatr Nephrol (2014) 29:329-32. doi:10.1007/s00467-013-2722-2
    • (2014) Pediatr Nephrol , vol.29 , pp. 329-332
    • Saland, J.1
  • 98
    • 84870534251 scopus 로고    scopus 로고
    • Eculizumab for atypical hemolytic uremic syndrome recurrence in renal transplantation
    • Zuber J, Le Quintrec M, Krid S, Bertoye C, Gueutin V, Lahoche A, et al. Eculizumab for atypical hemolytic uremic syndrome recurrence in renal transplantation. Am J Transplant (2012) 12:3337-54. doi:10.1111/j.1600-6143.2012.04252.x
    • (2012) Am J Transplant , vol.12 , pp. 3337-3354
    • Zuber, J.1    Le Quintrec, M.2    Krid, S.3    Bertoye, C.4    Gueutin, V.5    Lahoche, A.6
  • 99
    • 70350130833 scopus 로고    scopus 로고
    • Safety and long-term efficacy of eculizumab in a renal transplant patient with recurrent atypical hemolytic-uremic syndrome
    • Chatelet V, Frémeaux-Bacchi V, Lobbedez T, Ficheux M, Hurault de Ligny B. Safety and long-term efficacy of eculizumab in a renal transplant patient with recurrent atypical hemolytic-uremic syndrome. Am J Transplant (2009) 9:2644-5. doi:10.1111/j.1600-6143.2009.02817.x
    • (2009) Am J Transplant , vol.9 , pp. 2644-2645
    • Chatelet, V.1    Frémeaux-Bacchi, V.2    Lobbedez, T.3    Ficheux, M.4    Hurault de Ligny, B.5
  • 100
    • 80052268538 scopus 로고    scopus 로고
    • Complement activation during liver transplantation-special emphasis on patients with atypical hemolytic uremic syndrome
    • Koskinen AR, Tukiainen E, Arola J, Nordin A, Höckerstedt HK, Nilsson B, et al. Complement activation during liver transplantation-special emphasis on patients with atypical hemolytic uremic syndrome. Am J Transplant (2011) 11:1885-95. doi:10.1111/j.1600-6143.2011.03612.x
    • (2011) Am J Transplant , vol.11 , pp. 1885-1895
    • Koskinen, A.R.1    Tukiainen, E.2    Arola, J.3    Nordin, A.4    Höckerstedt, H.K.5    Nilsson, B.6
  • 101
    • 84877599866 scopus 로고    scopus 로고
    • Acute but transient release of terminal complement complex after reperfusion in clinical kidney transplantation
    • de Vries DK, van der Pol P, van Anken GE, van Gijlswijk DJ, Damman J, Lindeman JH, et al. Acute but transient release of terminal complement complex after reperfusion in clinical kidney transplantation. Transplantation (2013) 95:816-20. doi:10.1097/TP.0b013e31827e31c9
    • (2013) Transplantation , vol.95 , pp. 816-820
    • de Vries, D.K.1    van der Pol, P.2    van Anken, G.E.3    van Gijlswijk, D.J.4    Damman, J.5    Lindeman, J.H.6
  • 102
    • 79958849218 scopus 로고    scopus 로고
    • Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival
    • Kelly RJ, Hill A, Arnold LM, Brooksbank GL, Richards SJ, Cullen M, et al. Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival. Blood (2011) 117:6786-92. doi:10.1182/blood-2011-02-333997
    • (2011) Blood , vol.117 , pp. 6786-6792
    • Kelly, R.J.1    Hill, A.2    Arnold, L.M.3    Brooksbank, G.L.4    Richards, S.J.5    Cullen, M.6
  • 105
    • 77950955452 scopus 로고    scopus 로고
    • Efficacy of eculizumab in the treatment of recurrent atypical hemolytic-uremic syndrome after renal transplantation
    • Larrea CF, Cofan F, Oppenheimer F, Campistol JM, Escolar G, Lozano M. Efficacy of eculizumab in the treatment of recurrent atypical hemolytic-uremic syndrome after renal transplantation. Transplantation (2010) 89:903-4. doi:10.1097/TP.0b013e3181ccd80d
    • (2010) Transplantation , vol.89 , pp. 903-904
    • Larrea, C.F.1    Cofan, F.2    Oppenheimer, F.3    Campistol, J.M.4    Escolar, G.5    Lozano, M.6
  • 106
    • 84863724130 scopus 로고    scopus 로고
    • Eculizumab for the treatment of two recurrences of atypical hemolytic uremic syndrome in a kidney allograft
    • Alachkar N, Bagnasco SM, Montgomery RA. Eculizumab for the treatment of two recurrences of atypical hemolytic uremic syndrome in a kidney allograft. Transpl Int (2012) 25:e93-5. doi:10.1111/j.1432-2277.2012.01497.x
    • (2012) Transpl Int , vol.25 , pp. e93-e95
    • Alachkar, N.1    Bagnasco, S.M.2    Montgomery, R.A.3
  • 108
    • 77949570344 scopus 로고    scopus 로고
    • Maintenance of kidney function following treatment with eculizumab and discontinuation of plasma exchange after a third kidney transplant for atypical hemolytic uremic syndrome associated with a CFH mutation
    • Davin JC, Gracchi V, Bouts A, Groothoff J, Strain L, Goodship T. Maintenance of kidney function following treatment with eculizumab and discontinuation of plasma exchange after a third kidney transplant for atypical hemolytic uremic syndrome associated with a CFH mutation. Am J Kidney Dis (2010) 55:708-11. doi:10.1053/j.ajkd.2009.08.011
    • (2010) Am J Kidney Dis , vol.55 , pp. 708-711
    • Davin, J.C.1    Gracchi, V.2    Bouts, A.3    Groothoff, J.4    Strain, L.5    Goodship, T.6
  • 110
    • 84870161966 scopus 로고    scopus 로고
    • Tailored eculizumab therapy in the management of complement factor H-mediated atypical hemolytic uremic syndrome in an adult kidney transplant recipient: a case report
    • Xie L, Nester CM, Reed AI, Zhang Y, Smith RJ, Thomas CP. Tailored eculizumab therapy in the management of complement factor H-mediated atypical hemolytic uremic syndrome in an adult kidney transplant recipient: a case report. Transplant Proc (2012) 44:3037-40. doi:10.1016/j.transproceed.2012.07.141
    • (2012) Transplant Proc , vol.44 , pp. 3037-3040
    • Xie, L.1    Nester, C.M.2    Reed, A.I.3    Zhang, Y.4    Smith, R.J.5    Thomas, C.P.6
  • 111
    • 77950628343 scopus 로고    scopus 로고
    • Successful treatment of transplantation-associated thrombotic microangiopathy with recombinant human soluble thrombomodulin
    • Sakai M, Ikezoe T, Bandobashi K, Togitani K, Yokoyama A. Successful treatment of transplantation-associated thrombotic microangiopathy with recombinant human soluble thrombomodulin. Bone Marrow Transplant (2010) 45:803-5. doi:10.1038/bmt.2009.242
    • (2010) Bone Marrow Transplant , vol.45 , pp. 803-805
    • Sakai, M.1    Ikezoe, T.2    Bandobashi, K.3    Togitani, K.4    Yokoyama, A.5
  • 112
    • 74149086780 scopus 로고    scopus 로고
    • Therapeutic potential of complement modulation
    • Wagner E, Frank MM. Therapeutic potential of complement modulation. Nat Rev Drug Discov (2010) 9:43-56. doi:10.1038/nrd3011
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 43-56
    • Wagner, E.1    Frank, M.M.2


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