메뉴 건너뛰기




Volumn 13, Issue 3, 2013, Pages 663-675

Complement genes strongly predict recurrence and graft outcome in adult renal transplant recipients with atypical hemolytic and uremic syndrome

(15)  Le Quintrec, M a,b   Zuber, J c   Moulin, B d   Kamar, N e,f   Jablonski, M c   Lionet, A g   Chatelet, V h   Mousson, C i   Mourad, G j   Bridoux, F k   Cassuto, E l   Loirat, C m   Rondeau, E n   Delahousse, M a   Fremeaux Bacchi V o  

b INSERM   (France)

Author keywords

Acute rejection; atypical hemolytic and uremic syndrome; endothelial cell damage; mutations and polymorphisms in complement alternative pathway; renal transplantation; thrombotic microangiopathy

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; CALCINEURIN INHIBITOR; COMPLEMENT COMPONENT C3; COMPLEMENT FACTOR H; CYCLOSPORIN; ECULIZUMAB; FIBRINOGEN; HLA DR ANTIGEN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MEMBRANE COFACTOR PROTEIN; TACROLIMUS; THYMOCYTE ANTIBODY;

EID: 84874417661     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12077     Document Type: Article
Times cited : (217)

References (58)
  • 1
    • 0035722282 scopus 로고    scopus 로고
    • Thrombotic microangiopathy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura
    • Ruggenenti P, Noris M, Remuzzi G,. Thrombotic microangiopathy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. Kidney Int 2001; 60: 831-846.
    • (2001) Kidney Int , vol.60 , pp. 831-846
    • Ruggenenti, P.1    Noris, M.2    Remuzzi, G.3
  • 2
    • 34548400755 scopus 로고    scopus 로고
    • Outcome of renal transplantation in patients with non-Shiga toxin-associated hemolytic uremic syndrome: Prognostic significance of genetic background
    • Bresin E, Daina E, Noris M, et al. Outcome of renal transplantation in patients with non-Shiga toxin-associated hemolytic uremic syndrome: Prognostic significance of genetic background. Clin J Am Soc Nephrol 2006; 1: 88-99.
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 88-99
    • Bresin, E.1    Daina, E.2    Noris, M.3
  • 3
    • 77958587405 scopus 로고    scopus 로고
    • Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype
    • Noris M, Caprioli J, Bresin E, et al. Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype. Clin J Am Soc Nephrol 2010; 5: 1844-1859.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 1844-1859
    • Noris, M.1    Caprioli, J.2    Bresin, E.3
  • 4
    • 78650517945 scopus 로고    scopus 로고
    • New insights into postrenal transplant hemolytic uremic syndrome
    • Zuber J, Le Quintrec M, Sberro-Soussan R, et al. New insights into postrenal transplant hemolytic uremic syndrome. Nat Rev Nephrol 2011; 7: 23-35.
    • (2011) Nat Rev Nephrol , vol.7 , pp. 23-35
    • Zuber, J.1    Le Quintrec, M.2    Sberro-Soussan, R.3
  • 5
    • 70350279315 scopus 로고    scopus 로고
    • Atypical hemolytic-uremic syndrome
    • Noris M, Remuzzi G,. Atypical hemolytic-uremic syndrome. N Engl J Med 2009; 361: 1676-1687.
    • (2009) N Engl J Med , vol.361 , pp. 1676-1687
    • Noris, M.1    Remuzzi, G.2
  • 6
    • 77957577058 scopus 로고    scopus 로고
    • Atypical hemolytic uremic syndrome associated with mutations in complement regulator genes
    • Le Quintrec M, Roumenina L, Noris M, Fremeaux-Bacchi V,. Atypical hemolytic uremic syndrome associated with mutations in complement regulator genes. Semin Thromb Hemost 2010; 36: 641-652.
    • (2010) Semin Thromb Hemost , vol.36 , pp. 641-652
    • Le Quintrec, M.1    Roumenina, L.2    Noris, M.3    Fremeaux-Bacchi, V.4
  • 7
    • 75749153964 scopus 로고    scopus 로고
    • Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome
    • Bienaime F, Dragon-Durey MA, Regnier, CH, Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome. Kidney Int 2010; 77: 339-349.
    • (2010) Kidney Int , vol.77 , pp. 339-349
    • Bienaime, F.1    Dragon-Durey, M.A.2    Regnier, C.H.3
  • 8
    • 0242601270 scopus 로고    scopus 로고
    • Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: The C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease
    • Caprioli J, Castelletti F, Bucchioni S, et al. Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: The C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease. Hum Mol Genet 2003; 12: 3385-3395.
    • (2003) Hum Mol Genet , vol.12 , pp. 3385-3395
    • Caprioli, J.1    Castelletti, F.2    Bucchioni, S.3
  • 9
    • 33747159590 scopus 로고    scopus 로고
    • Genetics of HUS: The impact of MCP, CFH, and if mutations on clinical presentation, response to treatment, and outcome
    • Caprioli J, Noris M, Brioschi S, et al. Genetics of HUS: The impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome. Blood 2006; 108: 1267-1279.
    • (2006) Blood , vol.108 , pp. 1267-1279
    • Caprioli, J.1    Noris, M.2    Brioschi, S.3
  • 10
    • 34447127478 scopus 로고    scopus 로고
    • Recurrence of HUS due to CD46/MCP mutation after renal transplantation: A role for endothelial microchimerism
    • Fremeaux-Bacchi V, Arzouk N, Ferlicot S, Charpentier B, Snanoudj R, Durrbach A,. Recurrence of HUS due to CD46/MCP mutation after renal transplantation: A role for endothelial microchimerism. Am J Transplant 2007; 7: 2047-2051.
    • (2007) Am J Transplant , vol.7 , pp. 2047-2051
    • Fremeaux-Bacchi, V.1    Arzouk, N.2    Ferlicot, S.3    Charpentier, B.4    Snanoudj, R.5    Durrbach, A.6
  • 11
    • 19444369542 scopus 로고    scopus 로고
    • Complement factor I: A susceptibility gene for atypical haemolytic uraemic syndrome
    • Fremeaux-Bacchi V, Dragon-Durey MA, Blouin J, et al. Complement factor I: A susceptibility gene for atypical haemolytic uraemic syndrome. J Med Genet 2004; 41: e84.
    • (2004) J Med Genet , vol.41
    • Fremeaux-Bacchi, V.1    Dragon-Durey, M.A.2    Blouin, J.3
  • 12
    • 26944480588 scopus 로고    scopus 로고
    • The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: Evidence from two independent cohorts
    • Fremeaux-Bacchi V, Kemp EJ, Goodship JA, et al. The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: Evidence from two independent cohorts. J Med Genet 2005; 42: 852-856.
    • (2005) J Med Genet , vol.42 , pp. 852-856
    • Fremeaux-Bacchi, V.1    Kemp, E.J.2    Goodship, J.A.3
  • 13
    • 54049137505 scopus 로고    scopus 로고
    • Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome
    • Fremeaux-Bacchi V, Miller EC, Liszewski MK, et al. Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome. Blood 2008; 112: 4948-4952.
    • (2008) Blood , vol.112 , pp. 4948-4952
    • Fremeaux-Bacchi, V.1    Miller, E.C.2    Liszewski, M.K.3
  • 14
    • 33846094404 scopus 로고    scopus 로고
    • Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome
    • Goicoechea de Jorge E, Harris CL, Esparza-Gordillo J, et al. Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome. Proc Natl Acad Sci U S A 2007; 104: 240-245.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 240-245
    • Goicoechea De Jorge, E.1    Harris, C.L.2    Esparza-Gordillo, J.3
  • 15
    • 27744452766 scopus 로고    scopus 로고
    • Mutations in complement factor i predispose to development of atypical hemolytic uremic syndrome
    • Kavanagh D, Kemp EJ, Mayland E, et al. Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome. J Am Soc Nephrol 2005; 16: 2150-2155.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2150-2155
    • Kavanagh, D.1    Kemp, E.J.2    Mayland, E.3
  • 16
    • 70350475255 scopus 로고    scopus 로고
    • Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome
    • Roumenina LT, Jablonski M, Hue C, et al. Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome. Blood 2009; 114: 2837-2845.
    • (2009) Blood , vol.114 , pp. 2837-2845
    • Roumenina, L.T.1    Jablonski, M.2    Hue, C.3
  • 17
    • 20544437666 scopus 로고    scopus 로고
    • Anti-Factor H autoantibodies associated with atypical hemolytic uremic syndrome
    • Dragon-Durey MA, Loirat C, Cloarec S, et al. Anti-Factor H autoantibodies associated with atypical hemolytic uremic syndrome. J Am Soc Nephrol 2005; 16: 555-563.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 555-563
    • Dragon-Durey, M.A.1    Loirat, C.2    Cloarec, S.3
  • 18
    • 78649863686 scopus 로고    scopus 로고
    • Clinical features of anti-factor H autoantibody-associated hemolytic uremic syndrome
    • Dragon-Durey MA, Sethi SK, Bagga A, et al. Clinical features of anti-factor H autoantibody-associated hemolytic uremic syndrome. J Am Soc Nephrol 2010; 21: 2180-2187.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 2180-2187
    • Dragon-Durey, M.A.1    Sethi, S.K.2    Bagga, A.3
  • 19
    • 38949155911 scopus 로고    scopus 로고
    • Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency
    • Jozsi M, Licht C, Strobel S, et al. Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency. Blood 2008; 111: 1512-1514.
    • (2008) Blood , vol.111 , pp. 1512-1514
    • Jozsi, M.1    Licht, C.2    Strobel, S.3
  • 20
    • 84655168091 scopus 로고    scopus 로고
    • Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS
    • Ermini L, Goodship TH, Strain L, et al. Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS. Mol Immunol 2012; 49: 640-648.
    • (2012) Mol Immunol , vol.49 , pp. 640-648
    • Ermini, L.1    Goodship, T.H.2    Strain, L.3
  • 21
    • 79957691055 scopus 로고    scopus 로고
    • Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk
    • Heurich M, Martinez-Barricarte R, Francis NJ, et al. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proc Natl Acad Sci U S A 2011; 108: 8761-8766.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 8761-8766
    • Heurich, M.1    Martinez-Barricarte, R.2    Francis, N.J.3
  • 22
    • 34250329129 scopus 로고    scopus 로고
    • Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains
    • Pickering MC, de Jorge EG, Martinez-Barricarte R, et al. Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains. J Exp Med 2007; 204: 1249-1256.
    • (2007) J Exp Med , vol.204 , pp. 1249-1256
    • Pickering, M.C.1    De Jorge, E.G.2    Martinez-Barricarte, R.3
  • 23
    • 0030903510 scopus 로고    scopus 로고
    • Delayed graft function: Risk factors and implications for renal allograft survival
    • Ojo AO, Wolfe RA, Held PJ, Port FK, Schmouder RL,. Delayed graft function: Risk factors and implications for renal allograft survival. Transplantation 1997; 63: 968-974.
    • (1997) Transplantation , vol.63 , pp. 968-974
    • Ojo, A.O.1    Wolfe, R.A.2    Held, P.J.3    Port, F.K.4    Schmouder, R.L.5
  • 24
    • 0033820323 scopus 로고    scopus 로고
    • Cyclosporine and tacrolimus-associated thrombotic microangiopathy
    • Pham PT, Peng A, Wilkinson AH, et al. Cyclosporine and tacrolimus-associated thrombotic microangiopathy. Am J Kidney Dis 2000; 36: 844-850.
    • (2000) Am J Kidney Dis , vol.36 , pp. 844-850
    • Pham, P.T.1    Peng, A.2    Wilkinson, A.H.3
  • 25
    • 33644685230 scopus 로고    scopus 로고
    • Sirolimus-induced thrombotic microangiopathy is associated with decreased expression of vascular endothelial growth factor in kidneys
    • Sartelet H, Toupance O, Lorenzato M, et al. Sirolimus-induced thrombotic microangiopathy is associated with decreased expression of vascular endothelial growth factor in kidneys. Am J Transplant 2005; 5: 2441-2447.
    • (2005) Am J Transplant , vol.5 , pp. 2441-2447
    • Sartelet, H.1    Toupance, O.2    Lorenzato, M.3
  • 26
    • 33751164665 scopus 로고    scopus 로고
    • From humoral rejection to generalized thrombotic microangiopathy - Role of acquired ADAMTS13 deficiency in a renal allograft recipient
    • Ulinski T, Charpentier A, Colombat M, et al. From humoral rejection to generalized thrombotic microangiopathy-role of acquired ADAMTS13 deficiency in a renal allograft recipient. Am J Transplant 2006; 6: 3030-3036.
    • (2006) Am J Transplant , vol.6 , pp. 3030-3036
    • Ulinski, T.1    Charpentier, A.2    Colombat, M.3
  • 28
    • 33750855444 scopus 로고    scopus 로고
    • Atypical haemolytic uraemic syndrome associated with a hybrid complement gene
    • Venables JP, Strain L, Routledge D, et al. Atypical haemolytic uraemic syndrome associated with a hybrid complement gene. PLoS Med 2006; 3: e431.
    • (2006) PLoS Med , vol.3
    • Venables, J.P.1    Strain, L.2    Routledge, D.3
  • 29
    • 79957991917 scopus 로고    scopus 로고
    • Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility
    • Zhao J, Wu H, Khosravi M, et al. Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. PLoS Genet 2011; 7: e1002079.
    • (2011) PLoS Genet , vol.7
    • Zhao, J.1    Wu, H.2    Khosravi, M.3
  • 30
    • 0037158606 scopus 로고    scopus 로고
    • Thrombotic microangiopathies
    • Moake, JL,. Thrombotic microangiopathies. N Engl J Med 2002; 347: 589-600.
    • (2002) N Engl J Med , vol.347 , pp. 589-600
    • Moake, J.L.1
  • 31
    • 79953010396 scopus 로고    scopus 로고
    • Prevention of large-vessel stenoses in atypical hemolytic uremic syndrome associated with complement dysregulation
    • Davin JC, Majoie C, Groothoff J, et al. Prevention of large-vessel stenoses in atypical hemolytic uremic syndrome associated with complement dysregulation. Pediatr Nephrol 2011; 26: 155-157.
    • (2011) Pediatr Nephrol , vol.26 , pp. 155-157
    • Davin, J.C.1    Majoie, C.2    Groothoff, J.3
  • 32
    • 77957221636 scopus 로고    scopus 로고
    • Non-atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation
    • Loirat C, Macher MA, Elmaleh-Berges M, et al. Non-atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation. Nephrol Dial Transplant 2010; 25: 3421-3425.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 3421-3425
    • Loirat, C.1    MacHer, M.A.2    Elmaleh-Berges, M.3
  • 33
    • 77953008442 scopus 로고    scopus 로고
    • Myocardial infarction is a complication of factor H-associated atypical HUS
    • Sallee M, Daniel L, Piercecchi MD, et al. Myocardial infarction is a complication of factor H-associated atypical HUS. Nephrol Dial Transplant 2010; 25: 2028-2032.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 2028-2032
    • Sallee, M.1    Daniel, L.2    Piercecchi, M.D.3
  • 34
    • 0034034718 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome. Recurrence after renal transplantation. Groupe Cooperatif de l'Ile-de-France (GCIF)
    • Lahlou A, Lang P, Charpentier B, et al. Hemolytic uremic syndrome. Recurrence after renal transplantation. Groupe Cooperatif de l'Ile-de-France (GCIF). Medicine 2000; 79: 90-102.
    • (2000) Medicine , vol.79 , pp. 90-102
    • Lahlou, A.1    Lang, P.2    Charpentier, B.3
  • 35
    • 34547633064 scopus 로고    scopus 로고
    • Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome
    • Sellier-Leclerc AL, Fremeaux-Bacchi V, Dragon-Durey MA, et al. Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome. J Am Soc Nephrol 2007; 18: 2392-2400.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2392-2400
    • Sellier-Leclerc, A.L.1    Fremeaux-Bacchi, V.2    Dragon-Durey, M.A.3
  • 36
    • 65649106258 scopus 로고    scopus 로고
    • Liver-kidney transplantation to cure atypical hemolytic uremic syndrome
    • Saland JM, Ruggenenti P, Remuzzi G,. Liver-kidney transplantation to cure atypical hemolytic uremic syndrome. J Am Soc Nephrol 2009; 20: 940-949.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 940-949
    • Saland, J.M.1    Ruggenenti, P.2    Remuzzi, G.3
  • 37
    • 77954048044 scopus 로고    scopus 로고
    • Thrombotic microangiopathy after kidney transplantation
    • Noris M, Remuzzi G,. Thrombotic microangiopathy after kidney transplantation. Am J Transplant 2010; 10: 1517-1523.
    • (2010) Am J Transplant , vol.10 , pp. 1517-1523
    • Noris, M.1    Remuzzi, G.2
  • 38
    • 58249107188 scopus 로고    scopus 로고
    • Recurrent atypical hemolytic uremic syndrome associated with factor i mutation in a living related renal transplant recipient
    • Chan MR, Thomas CP, Torrealba JR, et al. Recurrent atypical hemolytic uremic syndrome associated with factor I mutation in a living related renal transplant recipient. Am J Kidney Dis 2009; 53: 321-326.
    • (2009) Am J Kidney Dis , vol.53 , pp. 321-326
    • Chan, M.R.1    Thomas, C.P.2    Torrealba, J.R.3
  • 39
    • 34248664063 scopus 로고    scopus 로고
    • A missense mutation in factor i (IF) predisposes to atypical haemolytic uraemic syndrome
    • Geelen, J, van den Dries, K, Roos, A, et al. A missense mutation in factor I (IF) predisposes to atypical haemolytic uraemic syndrome. Pediatr Nephrol 2007; 22: 371-375.
    • (2007) Pediatr Nephrol , vol.22 , pp. 371-375
    • Geelen, J.1    Van Den Dries, K.2    Roos, A.3
  • 40
    • 33745812440 scopus 로고    scopus 로고
    • Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome
    • Fremeaux-Bacchi V, Moulton EA, Kavanagh D, et al. Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome. J Am Soc Nephrol 2006; 17: 2017-2025.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2017-2025
    • Fremeaux-Bacchi, V.1    Moulton, E.A.2    Kavanagh, D.3
  • 41
    • 0242331610 scopus 로고    scopus 로고
    • Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome
    • Richards A, Kemp EJ, Liszewski MK, et al. Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome. Proc Natl Acad Sci U S A 2003; 100: 12966-12971.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12966-12971
    • Richards, A.1    Kemp, E.J.2    Liszewski, M.K.3
  • 42
    • 33751035523 scopus 로고    scopus 로고
    • Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome
    • Richards A, Kathryn Liszewski M, Kavanagh D, et al. Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome. Mol Immunol 2007; 44: 111-122.
    • (2007) Mol Immunol , vol.44 , pp. 111-122
    • Richards, A.1    Kathryn Liszewski, M.2    Kavanagh, D.3
  • 43
  • 45
    • 79958202220 scopus 로고    scopus 로고
    • Pre-emptive eculizumab and plasmapheresis for renal transplant in atypical hemolytic uremic syndrome
    • Nester C, Stewart Z, Myers D, et al. Pre-emptive eculizumab and plasmapheresis for renal transplant in atypical hemolytic uremic syndrome. Clin J Am Soc Nephrol 2011; 6: 1488-1494.
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 1488-1494
    • Nester, C.1    Stewart, Z.2    Myers, D.3
  • 46
    • 80052473232 scopus 로고    scopus 로고
    • Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome
    • Weitz M, Amon O, Bassler D, Koenigsrainer A, Nadalin S,. Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome. Pediatr Nephrol 2011; 26: 1325-1329.
    • (2011) Pediatr Nephrol , vol.26 , pp. 1325-1329
    • Weitz, M.1    Amon, O.2    Bassler, D.3    Koenigsrainer, A.4    Nadalin, S.5
  • 47
    • 77951876953 scopus 로고    scopus 로고
    • Prophylactic eculizumab after renal transplantation in atypical hemolytic-uremic syndrome
    • Zimmerhackl LB, Hofer J, Cortina G, et al. Prophylactic eculizumab after renal transplantation in atypical hemolytic-uremic syndrome. N Engl J Med 2010; 362: 1746-1748.
    • (2010) N Engl J Med , vol.362 , pp. 1746-1748
    • Zimmerhackl, L.B.1    Hofer, J.2    Cortina, G.3
  • 48
    • 84867993256 scopus 로고    scopus 로고
    • Eculizumab for atypical hemolytic uremic syndrome recurrence in renal transplantation
    • the French Study Group for atypical HUS
    • Zuber J, Le Quintrec M, Bertoye C, et al. the French Study Group for atypical HUS. Eculizumab for atypical hemolytic uremic syndrome recurrence in renal transplantation. Am J Transplant 2012; 8: 643-657.
    • (2012) Am J Transplant , vol.8 , pp. 643-657
    • Zuber, J.1    Le Quintrec, M.2    Bertoye, C.3
  • 49
    • 79954443076 scopus 로고    scopus 로고
    • Eculizumab induces long-term remission in recurrent post-transplant HUS associated with C3 gene mutation
    • Al-Akash SI, Almond PS, Savell VH, Jr., Gharaybeh SI, Hogue C,. Eculizumab induces long-term remission in recurrent post-transplant HUS associated with C3 gene mutation. Pediatr Nephrol 2011; 26: 613-619.
    • (2011) Pediatr Nephrol , vol.26 , pp. 613-619
    • Al-Akash, S.I.1    Almond, P.S.2    Savell, Jr.V.H.3    Gharaybeh, S.I.4    Hogue, C.5
  • 50
    • 77952558567 scopus 로고    scopus 로고
    • A favorable 3-year outcome of kidney transplantation in atypical hemolytic uremic syndrome associated with a factor H mutation: Case report
    • Albertazzi V, Bonucchi D, De Amicis S, Americo C, Ghiandai G, Cappelli G,. A favorable 3-year outcome of kidney transplantation in atypical hemolytic uremic syndrome associated with a factor H mutation: Case report. Transplant Proc 2010; 42: 1352-1354.
    • (2010) Transplant Proc , vol.42 , pp. 1352-1354
    • Albertazzi, V.1    Bonucchi, D.2    De Amicis, S.3    Americo, C.4    Ghiandai, G.5    Cappelli, G.6
  • 51
    • 80052304237 scopus 로고    scopus 로고
    • Long-term renal function under plasma exchange in atypical hemolytic uremic syndrome
    • Davin JC, Groothoff J, Gracchi V, Bouts A,. Long-term renal function under plasma exchange in atypical hemolytic uremic syndrome. Pediatr Nephrol 2011; 26: 1915-1916.
    • (2011) Pediatr Nephrol , vol.26 , pp. 1915-1916
    • Davin, J.C.1    Groothoff, J.2    Gracchi, V.3    Bouts, A.4
  • 53
    • 0142250921 scopus 로고    scopus 로고
    • Thrombotic microangiopathy after renal transplantation in the United States
    • Reynolds JC, Agodoa LY, Yuan CM, Abbott KC,. Thrombotic microangiopathy after renal transplantation in the United States. Am J Kidney Dis 2003; 42: 1058-1068.
    • (2003) Am J Kidney Dis , vol.42 , pp. 1058-1068
    • Reynolds, J.C.1    Agodoa, L.Y.2    Yuan, C.M.3    Abbott, K.C.4
  • 54
    • 0035959420 scopus 로고    scopus 로고
    • Recurrence of hemolytic uremic syndrome after renal transplantation in children: A report of the North American Pediatric Renal Transplant Cooperative Study
    • Quan A, Sullivan EK, Alexander SR,. Recurrence of hemolytic uremic syndrome after renal transplantation in children: A report of the North American Pediatric Renal Transplant Cooperative Study. Transplantation 2001; 72: 742-745.
    • (2001) Transplantation , vol.72 , pp. 742-745
    • Quan, A.1    Sullivan, E.K.2    Alexander, S.R.3
  • 55
    • 48349086641 scopus 로고    scopus 로고
    • Complement mutation-associated de novo thrombotic microangiopathy following kidney transplantation
    • Le Quintrec M, Lionet A, Kamar N, et al. Complement mutation-associated de novo thrombotic microangiopathy following kidney transplantation. Am J Transplant 2008; 8: 1694-1701.
    • (2008) Am J Transplant , vol.8 , pp. 1694-1701
    • Le Quintrec, M.1    Lionet, A.2    Kamar, N.3
  • 56
    • 0141590417 scopus 로고    scopus 로고
    • Renal transplantation in patients with hemolytic uremic syndrome: High rate of recurrence and increased incidence of acute rejections
    • Artz MA, Steenbergen EJ, Hoitsma AJ, Monnens LA, Wetzels JF,. Renal transplantation in patients with hemolytic uremic syndrome: High rate of recurrence and increased incidence of acute rejections. Transplantation 2003 76: 821-826.
    • (2003) Transplantation , vol.76 , pp. 821-826
    • Artz, M.A.1    Steenbergen, E.J.2    Hoitsma, A.J.3    Monnens, L.A.4    Wetzels, J.F.5
  • 57
    • 33644914494 scopus 로고    scopus 로고
    • Calcineurin inhibitor-free immunosuppression in renal allograft recipients with thrombotic microangiopathy/hemolytic uremic syndrome
    • Oyen O, Strom EH, Midtvedt K, et al. Calcineurin inhibitor-free immunosuppression in renal allograft recipients with thrombotic microangiopathy/hemolytic uremic syndrome. Am J Transplant 2006; 6: 412-418.
    • (2006) Am J Transplant , vol.6 , pp. 412-418
    • Oyen, O.1    Strom, E.H.2    Midtvedt, K.3
  • 58
    • 34648831382 scopus 로고    scopus 로고
    • Graft-derived complement as a mediator of transplant injury
    • Zhou W, Medof ME, Heeger PS, Sacks S,. Graft-derived complement as a mediator of transplant injury. Curr Opin Immunol 2007; 19: 569-576.
    • (2007) Curr Opin Immunol , vol.19 , pp. 569-576
    • Zhou, W.1    Medof, M.E.2    Heeger, P.S.3    Sacks, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.