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Volumn 8, Issue 11, 2012, Pages 643-657

Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3; ECULIZUMAB;

EID: 84867993256     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2012.214     Document Type: Review
Times cited : (421)

References (124)
  • 2
    • 70350279315 scopus 로고    scopus 로고
    • Atypical hemolytic-uremic syndrome
    • Noris, M. & Remuzzi, G. Atypical hemolytic-uremic syndrome. N. Engl. J. Med. 361, 1676-1687 (2009
    • (2009) N. Engl. J. Med , vol.361 , pp. 1676-1687
    • Noris, M.1    Remuzzi, G.2
  • 3
    • 79551595553 scopus 로고    scopus 로고
    • Alternative complement pathway assessment in patients with atypical HUS
    • Roumenina, L. T. et al. Alternative complement pathway assessment in patients with atypical HUS. J. Immunol. Methods 365, 8-26 (2011
    • (2011) J. Immunol. Methods , vol.365 , pp. 8-26
    • Roumenina, L.T.1
  • 4
    • 36849084660 scopus 로고    scopus 로고
    • Translational mini-review series on complement factor H: Genetics and disease associations of human complement factor H
    • de Cordoba, S. R. & de Jorge, E. G. Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H. Clin. Exp. Immunol. 151, 1-13 (2008
    • (2008) Clin. Exp. Immunol , vol.151 , pp. 1-13
    • De Cordoba, S.R.1    De Jorge, E.G.2
  • 5
    • 84864554927 scopus 로고    scopus 로고
    • Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies
    • Servais, A. et al. Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies. Kidney Int. 82, 454-464 (2012
    • (2012) Kidney Int , vol.82 , pp. 454-464
    • Servais, A.1
  • 6
    • 84858668780 scopus 로고    scopus 로고
    • Membranoproliferative glomerulonephritis-A new look at an old entity
    • Sethi, S. & Fervenza, F. C. Membranoproliferative glomerulonephritis - A new look at an old entity. N. Engl. J. Med. 366, 1119-1131 (2012
    • (2012) N. Engl. J. Med , vol.366 , pp. 1119-1131
    • Sethi, S.1    Fervenza, F.C.2
  • 7
    • 38849102544 scopus 로고    scopus 로고
    • Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice
    • Rose, K. L. et al. Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. J. Clin. Invest. 118, 608-618 (2008
    • (2008) J. Clin. Invest , vol.118 , pp. 608-618
    • Rose, K.L.1
  • 8
    • 59449088846 scopus 로고    scopus 로고
    • Eculizumab for congenital atypical hemolytic-uremic syndrome
    • Gruppo, R. A. & Rother, R. P. Eculizumab for congenital atypical hemolytic-uremic syndrome. N. Engl. J. Med. 360, 544-546 (2009
    • (2009) N. Engl. J. Med , vol.360 , pp. 544-546
    • Gruppo, R.A.1    Rother, R.P.2
  • 9
    • 59449107473 scopus 로고    scopus 로고
    • Eculizumab for atypical hemolytic-uremic syndrome
    • Nürnberger, J. et al. Eculizumab for atypical hemolytic-uremic syndrome. N. Engl. J. Med. 360, 542-544 (2009
    • (2009) N. Engl. J. Med , vol.360 , pp. 542-544
    • Nürnberger, J.1
  • 11
    • 33748904355 scopus 로고    scopus 로고
    • The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria
    • Hillmen, P. et al. The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria. N. Engl. J. Med. 355, 1233-1243 (2006
    • (2006) N. Engl. J. Med , vol.355 , pp. 1233-1243
    • Hillmen, P.1
  • 12
    • 79958849218 scopus 로고    scopus 로고
    • Long-Term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: Sustained efficacy and improved survival
    • Kelly, R. J. et al. Long-Term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: Sustained efficacy and improved survival. Blood 117, 6786-6792 (2011
    • (2011) Blood , vol.117 , pp. 6786-6792
    • Kelly, R.J.1
  • 13
    • 35948959015 scopus 로고    scopus 로고
    • Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria
    • Rother, R. P., Rollins, S. A., Mojcik, C. F., Brodsky R. A. & Bell, L. Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria. Nat. Biotechnol. 25, 1256-1264 (2007
    • (2007) Nat. Biotechnol , vol.25 , pp. 1256-1264
    • Rother, R.P.1    Rollins, S.A.2    Mojcik, C.F.3    Brodsky, R.A.4    Bell, L.5
  • 14
    • 84876080083 scopus 로고    scopus 로고
    • Electronic Medicines Compendium
    • Electronic Medicines Compendium. Soliris - Summary of Product Characteristics [online], http://www.medicines.org.uk/emc/medicine/19966/SPC/ soliris/ (2012
    • (2012) Soliris-Summary of Product Characteristics [Online
  • 15
    • 79960720836 scopus 로고    scopus 로고
    • U. S. Food. Drug Administration
    • U. S. Food and Drug Administration. Highlights of Prescribing Information: Soliris [online], http://www.accessdata.fda.gov/drugsatfda-docs/ label/2011/125166s172lbl.pdf (2011
    • (2011) Highlights of Prescribing Information: Soliris [Online
  • 16
    • 0038384134 scopus 로고    scopus 로고
    • Placental transport of immunoglobulin G
    • Simister, N. E. Placental transport of immunoglobulin G. Vaccine 21, 3365-3369 (2003
    • (2003) Vaccine , vol.21 , pp. 3365-3369
    • Simister, N.E.1
  • 17
    • 77950857026 scopus 로고    scopus 로고
    • The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab
    • Kelly, R. et al. The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab. Br. J. Haematol. 149, 446-450 (2010
    • (2010) Br. J. Haematol , vol.149 , pp. 446-450
    • Kelly, R.1
  • 18
    • 79957546158 scopus 로고    scopus 로고
    • Management of paroxysmal nocturnal haemoglobinuria: A personal view
    • Luzzatto, L., Gianfaldoni, G. & Notaro, R. Management of paroxysmal nocturnal haemoglobinuria: A personal view. Br. J. Haematol. 153, 709-720 (2011
    • (2011) Br. J. Haematol , vol.153 , pp. 709-720
    • Luzzatto, L.1    Gianfaldoni, G.2    Notaro, R.3
  • 19
    • 78650638514 scopus 로고    scopus 로고
    • Structures of C3b in complex with factors B and D give insight into complement convertase formation
    • Forneris, F. et al. Structures of C3b in complex with factors B and D give insight into complement convertase formation. Science 330, 1816-1820 (2010
    • (2010) Science , vol.330 , pp. 1816-1820
    • Forneris, F.1
  • 20
    • 67649221223 scopus 로고    scopus 로고
    • Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor
    • Rooijakkers, S. H. et al. Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor. Nat. Immunol. 10, 721-727 (2009
    • (2009) Nat. Immunol , vol.10 , pp. 721-727
    • Rooijakkers, S.H.1
  • 21
    • 79551581253 scopus 로고    scopus 로고
    • Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex
    • Laursen, N. S. et al. Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex. EMBO J. 30, 606-616 (2011
    • (2011) EMBO J. , vol.30 , pp. 606-616
    • Laursen, N.S.1
  • 22
    • 0037439378 scopus 로고    scopus 로고
    • Indications for the immunological evaluation of patients with meningitis
    • Overturf, G. D. Indications for the immunological evaluation of patients with meningitis. Clin. Infect. Dis. 36, 189-194 (2003
    • (2003) Clin. Infect. Dis , vol.36 , pp. 189-194
    • Overturf, G.D.1
  • 23
    • 78049408075 scopus 로고    scopus 로고
    • Infections of people with complement deficiencies and patients who have undergone splenectomy
    • Ram, S., Lewis, L. A. & Rice, P. A. Infections of people with complement deficiencies and patients who have undergone splenectomy. Clin. Microbiol. Rev. 23, 740-780 (2010
    • (2010) Clin. Microbiol. Rev , vol.23 , pp. 740-780
    • Ram, S.1    Lewis, L.A.2    Rice, P.A.3
  • 24
    • 84857828998 scopus 로고    scopus 로고
    • Long term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal hemoglobinuria (PNH
    • Brodsky, R. A. et al. Long term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal hemoglobinuria (PNH). Presented at the 52nd American Society of Hematology Annual Meeting (2010
    • (2010) Presented at the 52nd American Society of Hematology Annual Meeting
    • Brodsky, R.A.1
  • 25
    • 78651410434 scopus 로고    scopus 로고
    • The development of atypical hemolytic uremic syndrome depends on complement C5
    • de Jorge, E. G. et al. The development of atypical hemolytic uremic syndrome depends on complement C5. J. Am. Soc. Nephrol. 22, 137-145 (2011
    • (2011) J. Am. Soc. Nephrol , vol.22 , pp. 137-145
    • De Jorge, E.G.1
  • 26
    • 34250329129 scopus 로고    scopus 로고
    • Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains
    • Pickering, M. C. et al. Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains. J. Exp. Med. 204, 1249-1256 (2007
    • (2007) J. Exp. Med , vol.204 , pp. 1249-1256
    • Pickering, M.C.1
  • 27
    • 79954443076 scopus 로고    scopus 로고
    • Eculizumab induces long-Term remission in recurrent post-Transplant HUS associated with C3 gene mutation
    • Al-Akash, S. I., Almond, P. S., Savell, V. H. Jr, Gharaybeh S. I. & Hogue, C. Eculizumab induces long-Term remission in recurrent post-Transplant HUS associated with C3 gene mutation. Pediatr. Nephrol. 26, 613-619 (2011
    • (2011) Pediatr. Nephrol , vol.26 , pp. 613-619
    • Al-Akash, S.I.1    Almond, P.S.2    Savell Jr., V.H.3    Gharaybeh, S.I.4    Hogue, C.5
  • 30
    • 70350130833 scopus 로고    scopus 로고
    • Safety and long-Term efficacy of eculizumab in a renal transplant patient with recurrent atypical hemolytic-uremic syndrome
    • Chatelet, V., Fremeaux-Bacchi, V., Lobbedez, T., Ficheux, M. & de Ligny B. H. Safety and long-Term efficacy of eculizumab in a renal transplant patient with recurrent atypical hemolytic-uremic syndrome. Am. J. Transplant. 9, 2644-2645 (2009
    • (2009) Am. J. Transplant , vol.9 , pp. 2644-2645
    • Chatelet, V.1    Fremeaux-Bacchi, V.2    Lobbedez, T.3    Ficheux, M.4    De Ligny, B.H.5
  • 31
    • 78650507665 scopus 로고    scopus 로고
    • Eculizumab: Safety and efficacy after 17 months of treatment in a renal transplant patient with recurrent atypical hemolytic-uremic syndrome: Case report
    • Chatelet, V. et al. Eculizumab: Safety and efficacy after 17 months of treatment in a renal transplant patient with recurrent atypical hemolytic-uremic syndrome: Case report. Transplant. Proc. 42, 4353-4355 (2010
    • (2010) Transplant. Proc , vol.42 , pp. 4353-4355
    • Chatelet, V.1
  • 32
    • 84863981911 scopus 로고    scopus 로고
    • Eculizumab as rescue therapy for atypical hemolytic uremic syndrome with normal platelet count
    • Dorresteijn, E. M., van de Kar, N. C. & Cransberg, K. Eculizumab as rescue therapy for atypical hemolytic uremic syndrome with normal platelet count. Pediatr. Nephrol. 27, 1193-1195 (2012
    • (2012) Pediatr. Nephrol , vol.27 , pp. 1193-1195
    • Dorresteijn, E.M.1    Van De Kar, N.C.2    Cransberg, K.3
  • 33
    • 84868003869 scopus 로고    scopus 로고
    • Rescue therapy with eculizumab in a transient recipient with atypical haematologic-uraemic syndrome
    • Durán, C. E., Blasco, M., Maduell, F. & Campistol, J. M. Rescue therapy with eculizumab in a transient recipient with atypical haematologic-uraemic syndrome. Clin. Kidney J. 5, 28-30 (2012
    • (2012) Clin. Kidney J. , vol.5 , pp. 28-30
    • Durán, C.E.1    Blasco, M.2    Maduell, F.3    Campistol, J.M.4
  • 34
    • 84898865896 scopus 로고    scopus 로고
    • Eculizumab in atypical haemolytic-uraemic syndrome allows cessation of plasma exchange and dialysis
    • Kim, J. J., Waller S. C. & Reid, C. J. Eculizumab in atypical haemolytic-uraemic syndrome allows cessation of plasma exchange and dialysis. Clin. Kidney J. 5, 34-36 (2012
    • (2012) Clin. Kidney J. , vol.5 , pp. 34-36
    • Kim, J.J.1    Waller, S.C.2    Reid, C.J.3
  • 35
    • 79954433046 scopus 로고    scopus 로고
    • Efficacy of eculizumab in a patient with factor-H-associated atypical hemolytic uremic syndrome
    • Lapeyraque, A. L., Frémeaux-Bacchi, V. & Robitaille, P. Efficacy of eculizumab in a patient with factor-H-associated atypical hemolytic uremic syndrome. Pediatr. Nephrol. 26, 621-624 (2011
    • (2011) Pediatr. Nephrol , vol.26 , pp. 621-624
    • Lapeyraque, A.L.1    Frémeaux-Bacchi, V.2    Robitaille, P.3
  • 36
    • 77950955452 scopus 로고    scopus 로고
    • Efficacy of eculizumab in the treatment of recurrent atypical hemolytic-uremic syndrome after renal transplantation
    • Larrea, C. F. et al. Efficacy of eculizumab in the treatment of recurrent atypical hemolytic-uremic syndrome after renal transplantation. Transplantation 89, 903-904 (2010
    • (2010) Transplantation , vol.89 , pp. 903-904
    • Larrea, C.F.1
  • 38
    • 79958202220 scopus 로고    scopus 로고
    • Pre-emptive eculizumab and plasmapheresis for renal transplant in atypical hemolytic uremic syndrome
    • Nester, C. et al. Pre-emptive eculizumab and plasmapheresis for renal transplant in atypical hemolytic uremic syndrome. Clin. J. Am. Soc. Nephrol. 6, 1488-1494 (2011
    • (2011) Clin. J. Am. Soc. Nephrol , vol.6 , pp. 1488-1494
    • Nester, C.1
  • 39
    • 81255130615 scopus 로고    scopus 로고
    • Eculizumab safely reverses neurologic impairment and eliminates need for dialysis in severe atypical hemolytic uremic syndrome
    • Ohanian, M., Cable, C. & Halka, K. Eculizumab safely reverses neurologic impairment and eliminates need for dialysis in severe atypical hemolytic uremic syndrome. Clin. Pharmacol. 3, 5-12 (2011
    • (2011) Clin. Pharmacol , vol.3 , pp. 5-12
    • Ohanian, M.1    Cable, C.2    Halka, K.3
  • 40
    • 78649513705 scopus 로고    scopus 로고
    • Eculizumab therapy in an adult with plasma exchange-refractory atypical hemolytic uremic syndrome
    • Prescott, H. C., Wu, H. M., Cataland, S. R. & Baiocchi, R. A. Eculizumab therapy in an adult with plasma exchange-refractory atypical hemolytic uremic syndrome. Am. J. Hematol. 85, 976-977 (2010
    • (2010) Am. J. Hematol , vol.85 , pp. 976-977
    • Prescott, H.C.1    Wu, H.M.2    Cataland, S.R.3    Baiocchi, R.A.4
  • 41
    • 83155172386 scopus 로고    scopus 로고
    • Eculizumab in atypical hemolytic uremic syndrome: Long-Term clinical course and histological findings
    • Tschumi, S., Gugger, M., Bucher, B. S., Riedl, M. & Simonetti, G. D. Eculizumab in atypical hemolytic uremic syndrome: Long-Term clinical course and histological findings. Pediatr. Nephrol. 26, 2085-2088 (2011
    • (2011) Pediatr. Nephrol , vol.26 , pp. 2085-2088
    • Tschumi, S.1    Gugger, M.2    Bucher, B.S.3    Riedl, M.4    Simonetti, G.D.5
  • 42
    • 80052473232 scopus 로고    scopus 로고
    • Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome
    • Weitz, M., Amon, O., Bassler, D., Koenigsrainer, A. & Nadalin, S. Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome. Pediatr. Nephrol. 26, 1325-1329 (2011
    • (2011) Pediatr. Nephrol , vol.26 , pp. 1325-1329
    • Weitz, M.1    Amon, O.2    Bassler, D.3    Koenigsrainer, A.4    Nadalin, S.5
  • 43
    • 77951876953 scopus 로고    scopus 로고
    • Prophylactic eculizumab after renal transplantation in atypical hemolytic-uremic syndrome
    • Zimmerhackl, L. B. et al. Prophylactic eculizumab after renal transplantation in atypical hemolytic-uremic syndrome. N. Engl. J. Med. 362, 1746-1748 (2010
    • (2010) N. Engl. J. Med , vol.362 , pp. 1746-1748
    • Zimmerhackl, L.B.1
  • 45
    • 84867980876 scopus 로고    scopus 로고
    • Early treatment with eculizumab may be beneficial in atypical haemolytic uraemic syndrome
    • Garjau, M. et al. Early treatment with eculizumab may be beneficial in atypical haemolytic uraemic syndrome. Clin. Kidney J. 5, 31-33 (2012
    • (2012) Clin. Kidney J. , vol.5 , pp. 31-33
    • Garjau, M.1
  • 47
    • 77957602105 scopus 로고    scopus 로고
    • New treatment options for atypical hemolytic uremic syndrome with the complement inhibitor eculizumab
    • Kose, O., Zimmerhackl, L. B., Jungraithmayr, T., Mache C. & Nurnberger, J. New treatment options for atypical hemolytic uremic syndrome with the complement inhibitor eculizumab. Semin. Thromb. Hemost. 36, 669-672 (2010
    • (2010) Semin. Thromb. Hemost , vol.36 , pp. 669-672
    • Kose, O.1    Zimmerhackl, L.B.2    Jungraithmayr, T.3    Mache, C.4    Nurnberger, J.5
  • 48
    • 70349907791 scopus 로고    scopus 로고
    • Complement inhibitor eculizumab in atypical hemolytic uremic syndrome
    • Mache, C. J. et al. Complement inhibitor eculizumab in atypical hemolytic uremic syndrome. Clin. J. Am. Soc. Nephrol. 4, 1312-1316 (2009
    • (2009) Clin. J. Am. Soc. Nephrol , vol.4 , pp. 1312-1316
    • Mache, C.J.1
  • 49
    • 77949570344 scopus 로고    scopus 로고
    • Maintenance of kidney function following treatment with eculizumab and discontinuation of plasma exchange after a third kidney transplant for atypical hemolytic uremic syndrome associated with a CFH mutation
    • Davin, J. C. et al. Maintenance of kidney function following treatment with eculizumab and discontinuation of plasma exchange after a third kidney transplant for atypical hemolytic uremic syndrome associated with a CFH mutation. Am. J. Kidney Dis. 55, 708-711 (2010
    • (2010) Am. J. Kidney Dis , vol.55 , pp. 708-711
    • Davin, J.C.1
  • 50
    • 84867988065 scopus 로고    scopus 로고
    • Terminal complement blockade by eculizumab effectively reverses recurrent atypical hemolytic uremic syndrome after kidney transplantation
    • Heyne, N. Terminal complement blockade by eculizumab effectively reverses recurrent atypical hemolytic uremic syndrome after kidney transplantation. Presented at the 44th Annual Meeting of the American Society of Nephrology (2011
    • (2011) Presented at the 44th Annual Meeting of the American Society of Nephrology
    • Heyne, N.1
  • 51
    • 84885848118 scopus 로고    scopus 로고
    • Successful treatment of aHUS recurrence and arrest of plasma exchange resistant TMA post-renal transplantation with the terminal complement inhibitor eculizumab
    • Legault, D. & Boelkins, M. Successful treatment of aHUS recurrence and arrest of plasma exchange resistant TMA post-renal transplantation with the terminal complement inhibitor eculizumab. Presented at the 51st Annual Meeting of the American Society of Hematology (2009
    • (2009) Presented at the 51st Annual Meeting of the American Society of Hematology
    • Legault, D.1    Boelkins, M.2
  • 52
    • 78650517945 scopus 로고    scopus 로고
    • New insights into postrenal transplant hemolytic uremic syndrome
    • Zuber, J. et al. New insights into postrenal transplant hemolytic uremic syndrome. Nat. Rev. Nephrol. 7, 23-35 (2011
    • (2011) Nat. Rev. Nephrol , vol.7 , pp. 23-35
    • Zuber, J.1
  • 53
    • 62949147825 scopus 로고    scopus 로고
    • Soliris [online]
    • European Medicines Agency. Soliris [online], http://www.ema.europa.eu/ ema/index.jsp?curl=pages/medicines/human/medicines/000791/human-med-001055. jsp&mid=WC0b01ac058001d124 (2012
    • (2012) European Medicines Agency
  • 55
    • 84863208524 scopus 로고    scopus 로고
    • Renal transplantation under prophylactic eculizumab in atypical hemolytic uremic syndrome with CFH/CFHR1 hybrid protein
    • Krid, S. et al. Renal transplantation under prophylactic eculizumab in atypical hemolytic uremic syndrome with CFH/CFHR1 hybrid protein. Am. J. Transplant. 12, 1938-1944 (2012
    • (2012) Am. J. Transplant , vol.12 , pp. 1938-1944
    • Krid, S.1
  • 56
    • 80052268538 scopus 로고    scopus 로고
    • Complement activation during liver transplantation-special emphasis on patients with atypical hemolytic uremic syndrome
    • Koskinen, A. R. et al. Complement activation during liver transplantation-special emphasis on patients with atypical hemolytic uremic syndrome. Am. J. Transplant. 11, 1885-1895 (2011
    • (2011) Am. J. Transplant , vol.11 , pp. 1885-1895
    • Koskinen, A.R.1
  • 57
    • 77951853702 scopus 로고    scopus 로고
    • Eculizumab and renal transplantation in a patient with CAPS
    • Lonze, B. E., Singer, A. L. & Montgomery, R. A. Eculizumab and renal transplantation in a patient with CAPS. N. Engl. J. Med. 362, 1744-1745 (2010
    • (2010) N. Engl. J. Med , vol.362 , pp. 1744-1745
    • Lonze, B.E.1    Singer, A.L.2    Montgomery, R.A.3
  • 58
    • 84876086360 scopus 로고    scopus 로고
    • US National Library Of Medicine
    • US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT01029587 (2011
    • (2011) ClinicalTrials.gov [Online
  • 59
    • 84555210096 scopus 로고    scopus 로고
    • Terminal complement inhibition decreases antibody-mediated rejection in sensitized renal transplant recipients
    • Stegall, M. D. et al. Terminal complement inhibition decreases antibody-mediated rejection in sensitized renal transplant recipients. Am. J. Transplant. 11, 2405-2413 (2011
    • (2011) Am. J. Transplant , vol.11 , pp. 2405-2413
    • Stegall, M.D.1
  • 60
    • 84867985179 scopus 로고    scopus 로고
    • US National Library Of Medicine
    • US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT01399593 (2012
    • (2012) ClinicalTrials.gov [Online
  • 61
    • 84876086360 scopus 로고    scopus 로고
    • US National Library Of Medicine
    • US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT00844545 (2011
    • (2011) ClinicalTrials.gov [Online
  • 62
    • 84876086360 scopus 로고    scopus 로고
    • US National Library Of Medicine
    • US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT00838513 (2011
    • (2011) ClinicalTrials.gov [Online
  • 63
    • 84876086360 scopus 로고    scopus 로고
    • US National Library Of Medicine
    • US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT00844844 (2011
    • (2011) ClinicalTrials.gov [Online
  • 64
    • 84876086360 scopus 로고    scopus 로고
    • US National Library Of Medicine
    • US National Library of Medicine. ClinicalTrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT00844428 (2011
    • (2011) ClinicalTrials.gov [Online
  • 66
    • 84870540991 scopus 로고    scopus 로고
    • Continued improvement in renal function with sustained eculizumab in patients with atypical HUS resistant to plasma exchange/infusion
    • Greenbaum, L. A. et al. Continued improvement in renal function with sustained eculizumab in patients with atypical HUS resistant to plasma exchange/infusion. Presented at the 44th Annual Meeting of the American Society of Nephrology (2011
    • (2011) Presented at the 44th Annual Meeting of the American Society of Nephrology
    • Greenbaum, L.A.1
  • 67
    • 84870494580 scopus 로고    scopus 로고
    • Eculizumab is an effective long-Term treatment in patients with atypical hemolytic uremic syndrome resistant to plasma exchange/infusion: Results of an extension study
    • Greenbaum, L. A. et al. Eculizumab is an effective long-Term treatment in patients with atypical hemolytic uremic syndrome resistant to plasma exchange/infusion: Results of an extension study. Presented at the 53th Annual Meeting of the American Society of Hematology (2011
    • (2011) Presented at the 53th Annual Meeting of the American Society of Hematology
    • Greenbaum, L.A.1
  • 68
    • 84876076309 scopus 로고    scopus 로고
    • Eculizumab is an effective long-Term treatment in patients with atypical haemolytic uremic syndrome previously receiving chronic plasma exchange/infusion: Extension study results
    • Licht, C. et al. Eculizumab is an effective long-Term treatment in patients with atypical haemolytic uremic syndrome previously receiving chronic plasma exchange/infusion: Extension study results. Presented at the 53th Annual Meeting of the American Society of Hematology (2011
    • (2011) Presented at the 53th Annual Meeting of the American Society of Hematology
    • Licht, C.1
  • 71
    • 84857442742 scopus 로고    scopus 로고
    • Management of hemolytic uremic syndrome
    • Loirat, C., Saland, J. & Bitzan, M. Management of hemolytic uremic syndrome. Presse Med. 41, e115-e135 (2012
    • (2012) Presse Med , vol.41
    • Loirat, C.1    Saland, J.2    Bitzan, M.3
  • 72
    • 77954086014 scopus 로고    scopus 로고
    • Thrombotic microangiopathies: New insights and new challenges
    • Zipfel, P. F., Heinen, S. & Skerka, C. Thrombotic microangiopathies: New insights and new challenges. Curr. Opin. Nephrol. Hypertens. 19, 372-378 (2010
    • (2010) Curr. Opin. Nephrol. Hypertens , vol.19 , pp. 372-378
    • Zipfel, P.F.1    Heinen, S.2    Skerka, C.3
  • 73
    • 77956532403 scopus 로고    scopus 로고
    • Predictive features of severe acquired ADAMTS13 deficiency in idiopathic thrombotic microangiopathies: The French TMA reference center experience
    • Coppo, P. et al. Predictive features of severe acquired ADAMTS13 deficiency in idiopathic thrombotic microangiopathies: The French TMA reference center experience. Plos ONE 5, e10208 (2010
    • (2010) Plos One , vol.5
    • Coppo, P.1
  • 74
    • 33947594746 scopus 로고    scopus 로고
    • Prognostic value of anti-ADAMTS 13 antibody features (Ig isotype, titer, and inhibitory effect) in a cohort of 35 adult French patients undergoing a first episode of thrombotic microangiopathy with undetectable ADAMTS 13 activity
    • Ferrari, S. et al. Prognostic value of anti-ADAMTS 13 antibody features (Ig isotype, titer, and inhibitory effect) in a cohort of 35 adult French patients undergoing a first episode of thrombotic microangiopathy with undetectable ADAMTS 13 activity. Blood 109, 2815-2822 (2007
    • (2007) Blood , vol.109 , pp. 2815-2822
    • Ferrari, S.1
  • 75
    • 78549253211 scopus 로고    scopus 로고
    • How I treat patients with thrombotic thrombocytopenic purpura: 2010
    • George, J. N. How I treat patients with thrombotic thrombocytopenic purpura: 2010. Blood 116, 4060-4069 (2010
    • (2010) Blood , vol.116 , pp. 4060-4069
    • George, J.N.1
  • 76
    • 80051866867 scopus 로고    scopus 로고
    • A phase 2 study of the safety and efficacy of rituximab with plasma exchange in acute acquired thrombotic thrombocytopenic purpura
    • Scully, M. et al. A phase 2 study of the safety and efficacy of rituximab with plasma exchange in acute acquired thrombotic thrombocytopenic purpura. Blood 118, 1746-1753 (2011
    • (2011) Blood , vol.118 , pp. 1746-1753
    • Scully, M.1
  • 77
    • 77958587405 scopus 로고    scopus 로고
    • Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype
    • Noris, M. et al. Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype. Clin. J. Am. Soc. Nephrol. 5, 1844-1859 (2010
    • (2010) Clin. J. Am. Soc. Nephrol , vol.5 , pp. 1844-1859
    • Noris, M.1
  • 78
    • 34547633064 scopus 로고    scopus 로고
    • Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome
    • Sellier-Leclerc, A. L. et al. Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome. J. Am. Soc. Nephrol. 18, 2392-2400 (2007
    • (2007) J. Am. Soc. Nephrol , vol.18 , pp. 2392-2400
    • Sellier-Leclerc, A.L.1
  • 79
    • 79959776422 scopus 로고    scopus 로고
    • Eculizumab in severe Shiga-toxin-associated HUS
    • Lapeyraque, A. L. et al. Eculizumab in severe Shiga-toxin-associated HUS. N. Engl. J. Med. 364, 2561-2563 (2011
    • (2011) N. Engl. J. Med , vol.364 , pp. 2561-2563
    • Lapeyraque, A.L.1
  • 80
    • 84857190406 scopus 로고    scopus 로고
    • Eculizumab in acute recurrence of thrombotic microangiopathy after renal transplantation
    • Hadaya, K. et al. Eculizumab in acute recurrence of thrombotic microangiopathy after renal transplantation. Am. J. Transplant. 11, 2523-2527 (2011
    • (2011) Am. J. Transplant , vol.11 , pp. 2523-2527
    • Hadaya, K.1
  • 81
    • 84864485595 scopus 로고    scopus 로고
    • Induction of durable remission in recurrent catastrophic antiphospholipid syndrome via inhibition of terminal complement with eculizumab
    • Shapira, I., Andrade, D., Allen, S. L. & Salmon, J. E. Induction of durable remission in recurrent catastrophic antiphospholipid syndrome via inhibition of terminal complement with eculizumab. Arthritis Rheum. 64, 2719-2723 (2012
    • (2012) Arthritis Rheum , vol.64 , pp. 2719-2723
    • Shapira, I.1    Andrade, D.2    Allen, S.L.3    Salmon, J.E.4
  • 82
    • 84861526957 scopus 로고    scopus 로고
    • Eculizumab in the treatment of refractory idiopathic thrombotic thrombocytopenic purpura
    • Chapin, J., Weksler, B., Magro, C. & Laurence, J. Eculizumab in the treatment of refractory idiopathic thrombotic thrombocytopenic purpura. Br. J. Haematol. 157, 772-774 (2012
    • (2012) Br. J. Haematol , vol.157 , pp. 772-774
    • Chapin, J.1    Weksler, B.2    Magro, C.3    Laurence, J.4
  • 83
    • 84860474599 scopus 로고    scopus 로고
    • Complement activation in thrombotic thrombocytopenic purpura
    • Réti, M. et al. Complement activation in thrombotic thrombocytopenic purpura. J. Thromb. Haemost. 10, 791-798 (2012
    • (2012) J. Thromb. Haemost , vol.10 , pp. 791-798
    • Réti, M.1
  • 85
    • 77952556624 scopus 로고    scopus 로고
    • Pregnancy-Associated hemolytic uremic syndrome revisited in the era of complement gene mutations
    • Fakhouri, F. et al. Pregnancy-Associated hemolytic uremic syndrome revisited in the era of complement gene mutations. J. Am. Soc. Nephrol. 21, 859-867 (2010
    • (2010) J. Am. Soc. Nephrol , vol.21 , pp. 859-867
    • Fakhouri, F.1
  • 86
    • 48349086641 scopus 로고    scopus 로고
    • Complement mutation-Associated de novo thrombotic microangiopathy following kidney transplantation
    • Le Quintrec, M. et al. Complement mutation-Associated de novo thrombotic microangiopathy following kidney transplantation. Am. J. Transplant. 8, 1694-1701 (2008
    • (2008) Am. J. Transplant , vol.8 , pp. 1694-1701
    • Le Quintrec, M.1
  • 87
    • 79959390955 scopus 로고    scopus 로고
    • Eculizumab for the treatment of de novo thrombotic microangiopathy post simultaneous pancreas-kidney transplantation-A case report
    • Chandran, S., Baxter-Lowe, L., Olson, J. L., Tomlanovich, S. J. & Webber, A. Eculizumab for the treatment of de novo thrombotic microangiopathy post simultaneous pancreas-kidney transplantation - A case report. Transplant. Proc. 43, 2097-2101 (2011
    • (2011) Transplant. Proc , vol.43 , pp. 2097-2101
    • Chandran, S.1    Baxter-Lowe, L.2    Olson, J.L.3    Tomlanovich, S.J.4    Webber, A.5
  • 88
    • 80054767700 scopus 로고    scopus 로고
    • Successful treatment of de novo posttransplant thrombotic microangiopathy with eculizumab
    • Wilson, C. H. et al. Successful treatment of de novo posttransplant thrombotic microangiopathy with eculizumab. Transplantation 92, e42-e43 (2011
    • (2011) Transplantation , vol.92
    • Wilson, C.H.1
  • 89
    • 57649241639 scopus 로고    scopus 로고
    • Factor H, membrane cofactor protein, and factor I mutations in patients with hemolysis, elevated liver enzymes, and low platelet count syndrome
    • Fakhouri, F. et al. Factor H, membrane cofactor protein, and factor I mutations in patients with hemolysis, elevated liver enzymes, and low platelet count syndrome. Blood 112, 4542-4545 (2008
    • (2008) Blood , vol.112 , pp. 4542-4545
    • Fakhouri, F.1
  • 91
    • 79953691827 scopus 로고    scopus 로고
    • Mutations in complement regulatory proteins predispose to preeclampsia: A genetic analysis of the PROMISSE cohort
    • Salmon, J. E. et al. Mutations in complement regulatory proteins predispose to preeclampsia: A genetic analysis of the PROMISSE cohort. Plos Med. 8, e1001013 (2011
    • (2011) Plos Med , vol.8
    • Salmon, J.E.1
  • 92
    • 77951621575 scopus 로고    scopus 로고
    • Pulse cyclophosphamide therapy and clinical remission in atypical hemolytic uremic syndrome with anti-complement factor H autoantibodies
    • Boyer, O. et al. Pulse cyclophosphamide therapy and clinical remission in atypical hemolytic uremic syndrome with anti-complement factor H autoantibodies. Am. J. Kidney Dis. 55, 923-927 (2010
    • (2010) Am. J. Kidney Dis , vol.55 , pp. 923-927
    • Boyer, O.1
  • 93
    • 78649863686 scopus 로고    scopus 로고
    • Clinical features of anti-factor H autoantibody-Associated hemolytic uremic syndrome
    • Dragon-Durey, M. A. et al. Clinical features of anti-factor H autoantibody-Associated hemolytic uremic syndrome. J. Am. Soc. Nephrol. 21, 2180-2187 (2010
    • (2010) J. Am. Soc. Nephrol , vol.21 , pp. 2180-2187
    • Dragon-Durey, M.A.1
  • 94
    • 44449165673 scopus 로고    scopus 로고
    • Successful pre-Transplant management of a patient with anti-factor H autoantibodies-Associated haemolytic uraemic syndrome
    • Kwon, T. et al. Successful pre-Transplant management of a patient with anti-factor H autoantibodies-Associated haemolytic uraemic syndrome. Nephrol. Dial. Transplant. 23, 2088-2090 (2008
    • (2008) Nephrol. Dial. Transplant , vol.23 , pp. 2088-2090
    • Kwon, T.1
  • 95
    • 65249156546 scopus 로고    scopus 로고
    • Anti-factor H autoantibodies in a fifth renal transplant recipient with atypical hemolytic and uremic syndrome
    • Le Quintrec, M. et al. Anti-factor H autoantibodies in a fifth renal transplant recipient with atypical hemolytic and uremic syndrome. Am. J. Transplant. 9, 1223-1229 (2009
    • (2009) Am. J. Transplant , vol.9 , pp. 1223-1229
    • Le Quintrec, M.1
  • 96
    • 75649133611 scopus 로고    scopus 로고
    • Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome
    • Moore, I. et al. Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome. Blood 115, 379-387 (2010
    • (2010) Blood , vol.115 , pp. 379-387
    • Moore, I.1
  • 97
    • 61549117207 scopus 로고    scopus 로고
    • Guideline for the investigation and initial therapy of diarrhea-negative hemolytic uremic syndrome
    • Ariceta, G. et al. Guideline for the investigation and initial therapy of diarrhea-negative hemolytic uremic syndrome. Pediatr. Nephrol. 24, 687-696 (2009
    • (2009) Pediatr. Nephrol , vol.24 , pp. 687-696
    • Ariceta, G.1
  • 98
    • 72249097911 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom
    • Taylor, C. M., Machin, S., Wigmore, S. J. & Goodship, T. H. Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom. Br. J. Haematol. 148, 37-47 (2010
    • (2010) Br. J. Haematol , vol.148 , pp. 37-47
    • Taylor, C.M.1    Machin, S.2    Wigmore, S.J.3    Goodship, T.H.4
  • 99
    • 34548799240 scopus 로고    scopus 로고
    • Complications of apheresis in children
    • Michon, B. et al. Complications of apheresis in children. Transfusion 47, 1837-1842 (2007
    • (2007) Transfusion , vol.47 , pp. 1837-1842
    • Michon, B.1
  • 100
    • 56449089731 scopus 로고    scopus 로고
    • World apheresis registry data from 2003 to 2007, the pediatric and adolescent side of the registry
    • Witt, V. et al. World apheresis registry data from 2003 to 2007, the pediatric and adolescent side of the registry. Transfus. Apher. Sci. 39, 255-260 (2008
    • (2008) Transfus. Apher. Sci , vol.39 , pp. 255-260
    • Witt, V.1
  • 101
    • 84871026804 scopus 로고    scopus 로고
    • Decreasing frequency of plasma exchange complications in patients treated for thrombotic thrombocytopenic purpura-hemolytic uremic syndrome 1996 to 2011
    • Som, S. et al. Decreasing frequency of plasma exchange complications in patients treated for thrombotic thrombocytopenic purpura-hemolytic uremic syndrome, 1996 to 2011. Transfusion http://dx.doi.org/10.1111/j.1537-29952012. 03646.x.
    • Transfusion
    • Som, S.1
  • 102
    • 84860711841 scopus 로고    scopus 로고
    • A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain-of-function
    • Roumenina, L. T. et al. A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain-of-function. Blood 119, 4182-4191 (2012
    • (2012) Blood , vol.119 , pp. 4182-4191
    • Roumenina, L.T.1
  • 103
    • 77953008442 scopus 로고    scopus 로고
    • Myocardial infarction is a complication of factor H-associated atypical HUS
    • Sallee, M. et al. Myocardial infarction is a complication of factor H-associated atypical HUS. Nephrol. Dial. Transplant. 25, 2028-2032 (2010
    • (2010) Nephrol. Dial. Transplant , vol.25 , pp. 2028-2032
    • Sallee, M.1
  • 104
    • 77957221636 scopus 로고    scopus 로고
    • Non-Atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation
    • Loirat, C. et al. Non-Atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation. Nephrol. Dial. Transplant. 10, 3421-3425 (2010
    • (2010) Nephrol. Dial. Transplant , vol.10 , pp. 3421-3425
    • Loirat, C.1
  • 106
    • 75749153964 scopus 로고    scopus 로고
    • Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome
    • Bienaime, F. et al. Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome. Kidney Int. 77, 339-349 (2010
    • (2010) Kidney Int , vol.77 , pp. 339-349
    • Bienaime, F.1
  • 108
    • 82255195370 scopus 로고    scopus 로고
    • Molecular mechanisms of inflammation and tissue injury after major trauma-Is complement the "bad guy"?
    • Neher, M. D., Weckbach, S., Flierl, M. A., Huber-Lang, M. S. & Stahel, P. F. Molecular mechanisms of inflammation and tissue injury after major trauma - is complement the "bad guy"? J. Biomed. Sci. 18, 90 (2011
    • (2011) J. Biomed. Sci , vol.18 , pp. 90
    • Neher, M.D.1    Weckbach, S.2    Flierl, M.A.3    Huber-Lang, M.S.4    Stahel, P.F.5
  • 109
    • 77956320935 scopus 로고    scopus 로고
    • Pregnancy in PNH: Another eculizumab baby
    • Marasca, R. et al. Pregnancy in PNH: Another eculizumab baby. Br. J. Haematol. 150, 707-708 (2010
    • (2010) Br. J. Haematol , vol.150 , pp. 707-708
    • Marasca, R.1
  • 110
    • 49349112382 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome recurrence after renal transplantation
    • Loirat, C. & Fremeaux-Bacchi, V. Hemolytic uremic syndrome recurrence after renal transplantation. Pediatr. Transplant. 12, 619-629 (2008
    • (2008) Pediatr. Transplant , vol.12 , pp. 619-629
    • Loirat, C.1    Fremeaux-Bacchi, V.2
  • 111
    • 84870534251 scopus 로고    scopus 로고
    • Eculizumab for atypical hemolytic uremic syndrome recurrence in renal transplantation
    • Zuber, J. et al. Eculizumab for atypical hemolytic uremic syndrome recurrence in renal transplantation. Am. J. Transplant. http://dx.doi.org/10. 1111/j.1600-6143.2012.04252.x.
    • Am. J. Transplant
    • Zuber, J.1
  • 112
    • 65649106258 scopus 로고    scopus 로고
    • Liver-kidney transplantation to cure atypical hemolytic uremic syndrome
    • Saland, J. M., Ruggenenti P. & Remuzzi, G. Liver-kidney transplantation to cure atypical hemolytic uremic syndrome. J. Am. Soc. Nephrol. 20, 940-949 (2009
    • (2009) J. Am. Soc. Nephrol , vol.20 , pp. 940-949
    • Saland, J.M.1    Ruggenenti, P.2    Remuzzi, G.3
  • 113
    • 0036900126 scopus 로고    scopus 로고
    • The molecular basis for hereditary porcine membranoproliferative glomerulonephritis type II: Point mutations in the factor H coding sequence block protein secretion
    • Hegasy, G. A., Manuelian, T., Hogasen, K., Jansen, J. H. & Zipfel, P. F. The molecular basis for hereditary porcine membranoproliferative glomerulonephritis type II: Point mutations in the factor H coding sequence block protein secretion. Am. J. Pathol. 161, 2027-2034 (2002
    • (2002) Am. J. Pathol , vol.161 , pp. 2027-2034
    • Hegasy, G.A.1    Manuelian, T.2    Hogasen, K.3    Jansen, J.H.4    Zipfel, P.F.5
  • 114
    • 0036699540 scopus 로고    scopus 로고
    • Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H
    • Pickering, M. C. et al. Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Nat. Genet. 31, 424-428 (2002
    • (2002) Nat. Genet , vol.31 , pp. 424-428
    • Pickering, M.C.1
  • 115
    • 31544450767 scopus 로고    scopus 로고
    • Severity of primary MPGN, rather than MPGN type, determines renal survival and post-Transplantation recurrence risk
    • Little, M. A., Dupont, P., Campbell, E., Dorman, A. & Walshe, J. J. Severity of primary MPGN, rather than MPGN type, determines renal survival and post-Transplantation recurrence risk. Kidney Int. 69, 504-511 (2006
    • (2006) Kidney Int , vol.69 , pp. 504-511
    • Little, M.A.1    Dupont, P.2    Campbell, E.3    Dorman, A.4    Walshe, J.J.5
  • 116
    • 77954761090 scopus 로고    scopus 로고
    • Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice
    • Fakhouri, F. et al. Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice. Kidney Int. 78, 279-286 (2010
    • (2010) Kidney Int , vol.78 , pp. 279-286
    • Fakhouri, F.1
  • 117
    • 33745441327 scopus 로고    scopus 로고
    • Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice
    • Pickering, M. C. et al. Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice. Proc. Natl Acad. Sci. USA 103, 9649-9654 (2006
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 9649-9654
    • Pickering, M.C.1
  • 118
    • 84860779074 scopus 로고    scopus 로고
    • Eculizumab for dense deposit disease and C3 glomerulonephritis
    • Bomback, A. S. et al. Eculizumab for dense deposit disease and C3 glomerulonephritis. Clin. J. Am. Soc. Nephrol. 7, 748-756 (2012
    • (2012) Clin. J. Am. Soc. Nephrol , vol.7 , pp. 748-756
    • Bomback, A.S.1
  • 119
    • 84858671433 scopus 로고    scopus 로고
    • Eculizumab in a patient with dense-deposit disease
    • Daina, E., Noris, M. & Remuzzi, G. Eculizumab in a patient with dense-deposit disease. N. Engl. J. Med. 366, 1161-1163 (2012
    • (2012) N. Engl. J. Med , vol.366 , pp. 1161-1163
    • Daina, E.1    Noris, M.2    Remuzzi, G.3
  • 120
    • 84858633062 scopus 로고    scopus 로고
    • Eculizumab and refractory membranoproliferative glomerulonephritis
    • Radhakrishnan, S. et al. Eculizumab and refractory membranoproliferative glomerulonephritis. N. Engl. J. Med. 366, 1165-1166 (2012
    • (2012) N. Engl. J. Med , vol.366 , pp. 1165-1166
    • Radhakrishnan, S.1
  • 121
    • 84858661698 scopus 로고    scopus 로고
    • Eculizumab for the treatment of dense-deposit disease
    • Vivarelli, M., Pasini, A. & Emma, F. Eculizumab for the treatment of dense-deposit disease. N. Engl. J. Med. 366, 1163-1165 (2012
    • (2012) N. Engl. J. Med , vol.366 , pp. 1163-1165
    • Vivarelli, M.1    Pasini, A.2    Emma, F.3
  • 122
    • 84859421387 scopus 로고    scopus 로고
    • Recurrent dense deposit disease after renal transplantation: An emerging role for complementary therapies
    • McCaughan, J. A., O'Rourke D. M. & Courtney, A. E. Recurrent dense deposit disease after renal transplantation: An emerging role for complementary therapies. Am. J. Transplant. 12, 1046-1051 (2012
    • (2012) Am. J. Transplant , vol.12 , pp. 1046-1051
    • McCaughan, J.A.1    O'Rourke, D.M.2    Courtney, A.E.3
  • 123
    • 84863512960 scopus 로고    scopus 로고
    • Pathology after eculizumab in dense deposit disease and C3 GN
    • Herlitz, L. C. et al. Pathology after eculizumab in dense deposit disease and C3 GN. J. Am. Soc. Nephrol. 23, 1229-1237 (2012
    • (2012) J. Am. Soc. Nephrol , vol.23 , pp. 1229-1237
    • Herlitz, L.C.1
  • 124
    • 80052290190 scopus 로고    scopus 로고
    • Insufficient protection by Neisseria meningitidis vaccination alone during eculizumab therapy
    • Bouts, A., Monnens, L., Davin, J. C., Struijk, G. & Spanjaard, L. Insufficient protection by Neisseria meningitidis vaccination alone during eculizumab therapy. Pediatr. Nephrol. 26, 1919-1920 (2011
    • (2011) Pediatr. Nephrol , vol.26 , pp. 1919-1920
    • Bouts, A.1    Monnens, L.2    Davin, J.C.3    Struijk, G.4    Spanjaard, L.5


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