Peptidic exenatide and herbal catalpol mediate neuroprotection via the hippocampal GLP-1 receptor/β-endorphin pathway

Pharmacological Research

Volumn 102, Issue , 2015, Pages 276-285

  Jia, Yu ^a   Gong, Nian ^a   Li, Teng Fei ^a   Zhu, Bin ^a   Wang, Yong Xiang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Catalpola; Exenatide; Glucagon like peptide 1 receptor (GLP 1R); Microglia; Neuroprotection; endorphin

Indexed keywords

BETA ENDORPHIN; CATALPOL; EXENDIN 4; EXENDIN[9-39]; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; HORMONE RECEPTOR BLOCKING AGENT; INSULIN; NALOXONE; UNCLASSIFIED DRUG; GLUCAGON LIKE PEPTIDE 1; IRIDOID; NEUROPROTECTIVE AGENT; OPIATE RECEPTOR; PEPTIDE; VENOM;

ADULT; ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BEHAVIOR DISORDER; BRAIN INFARCTION SIZE; BRAIN NERVE CELL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG EFFICACY; DRUG RECEPTOR BINDING; GLYCEMIC CONTROL; HIPPOCAMPUS; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; INSULIN RELEASE; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NEWBORN; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TRANSIENT ISCHEMIC ATTACK; ANIMAL; CELL CULTURE; DRUG EFFECTS; METABOLISM; NERVE CELL; WISTAR RAT;

ANIMALS; BETA-ENDORPHIN; CELLS, CULTURED; GLUCAGON-LIKE PEPTIDE 1; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; HIPPOCAMPUS; INSULIN; IRIDOID GLUCOSIDES; MALE; MICROGLIA; NEURONS; NEUROPROTECTION; NEUROPROTECTIVE AGENTS; PEPTIDES; RATS; RATS, WISTAR; RECEPTORS, OPIOID; VENOMS;

EID: 84947060444     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2015.10.008     Document Type: Article

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