PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Yu, Guanzhen ^a,d   Yu, Wenlong ^b   Jin, Guangzhi ^b   Xu, Dongyun ^a   Chen, Ying ^c   Xia, Tian ^c,d   Yu, Allan ^d   Fang, Wenzheng ^a   Zhang, Xiaoli ^e   Li, Zhaosheng ^c   Xie, Keping ^d  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Eastern Hepatobiliary Hospital   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e No 411 Hospital of PLA   (China)

Author keywords

Biomarkers; Hilar cholangiocarcinoma; Metabolism; PKM2; Prognosis

Indexed keywords

HEXOKINASE 1; METFORMIN; PKM2 PROTEIN; PYRUVATE KINASE; SYNDECAN 2; UNCLASSIFIED DRUG; CARRIER PROTEIN; HEXOKINASE; HK1 PROTEIN, HUMAN; ISOPROTEIN; MEMBRANE PROTEIN; SDC2 PROTEIN, HUMAN; THYROID HORMONE; THYROID HORMONE-BINDING PROTEINS;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BILE DUCT CARCINOMA; CANCER PROGNOSIS; CHOLANGITIS; CONTROLLED STUDY; DISEASE FREE SURVIVAL; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; OVERALL SURVIVAL; PERINEURAL INVASION; PROTEIN EXPRESSION; TUMOR GROWTH; TUMOR RECURRENCE; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; KLATSKIN TUMOR; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; PROGNOSIS; TUMOR CELL LINE;

ADULT; AGED; ANIMALS; CARRIER PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEXOKINASE; HUMANS; KLATSKIN TUMOR; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; PROTEIN ISOFORMS; SYNDECAN-2; THYROID HORMONES;

EID: 84946925542     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0462-6     Document Type: Article

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