-
1
-
-
44449097168
-
AGE-RAGE system and carcinogenesis
-
R. Abe, and S. Yamagishi AGE-RAGE system and carcinogenesis Curr. Pharm. Des. 14 2008 940 945
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 940-945
-
-
Abe, R.1
Yamagishi, S.2
-
2
-
-
84863601677
-
Metformin reduces endogenous reactive oxygen species and associated DNA damage
-
C. Algire, O. Moiseeva, X. Deschenes-Simard, L. Amrein, L. Petruccelli, E. Birman, B. Viollet, G. Ferbeyre, and M.N. Pollak Metformin reduces endogenous reactive oxygen species and associated DNA damage Cancer Prev. Res. (Phila) 5 2012 536 543
-
(2012)
Cancer Prev. Res. (Phila)
, vol.5
, pp. 536-543
-
-
Algire, C.1
Moiseeva, O.2
Deschenes-Simard, X.3
Amrein, L.4
Petruccelli, L.5
Birman, E.6
Viollet, B.7
Ferbeyre, G.8
Pollak, M.N.9
-
3
-
-
84861540166
-
Antiproliferative action of metformin in human lung cancer cell lines
-
H. Ashinuma, Y. Takiguchi, S. Kitazono, M. Kitazono-Saitoh, A. Kitamura, T. Chiba, Y. Tada, K. Kurosu, E. Sakaida, I. Sekine, N. Tanabe, A. Iwama, O. Yokosuka, and K. Tatsumi Antiproliferative action of metformin in human lung cancer cell lines Oncol. Rep. 28 2012 8 14
-
(2012)
Oncol. Rep.
, vol.28
, pp. 8-14
-
-
Ashinuma, H.1
Takiguchi, Y.2
Kitazono, S.3
Kitazono-Saitoh, M.4
Kitamura, A.5
Chiba, T.6
Tada, Y.7
Kurosu, K.8
Sakaida, E.9
Sekine, I.10
Tanabe, N.11
Iwama, A.12
Yokosuka, O.13
Tatsumi, K.14
-
4
-
-
79951592967
-
Metformin and the incidence of prostate cancer in patients with type 2 diabetes
-
L. Azoulay, S. Dell'Aniello, B. Gagnon, M. Pollak, and S. Suissa Metformin and the incidence of prostate cancer in patients with type 2 diabetes Cancer Epidemiol. Biomarkers Prev. 20 2011 337 344
-
(2011)
Cancer Epidemiol. Biomarkers Prev.
, vol.20
, pp. 337-344
-
-
Azoulay, L.1
Dell'Aniello, S.2
Gagnon, B.3
Pollak, M.4
Suissa, S.5
-
5
-
-
58049192725
-
Long-term all-cause mortality in cancer patients with preexisting diabetes mellitus: A systematic review and meta-analysis
-
B.B. Barone, H.C. Yeh, C.F. Snyder, K.S. Peairs, K.B. Stein, R.L. Derr, A.C. Wolff, and F.L. Brancati Long-term all-cause mortality in cancer patients with preexisting diabetes mellitus: a systematic review and meta-analysis JAMA-J. Am. Med. Assoc. 300 2008 2754 2764
-
(2008)
JAMA-J. Am. Med. Assoc.
, vol.300
, pp. 2754-2764
-
-
Barone, B.B.1
Yeh, H.C.2
Snyder, C.F.3
Peairs, K.S.4
Stein, K.B.5
Derr, R.L.6
Wolff, A.C.7
Brancati, F.L.8
-
6
-
-
77951608210
-
Postoperative mortality in cancer patients with preexisting diabetes: Systematic review and meta-analysis
-
B.B. Barone, H.C. Yeh, C.F. Snyder, K.S. Peairs, K.B. Stein, R.L. Derr, A.C. Wolff, and F.L. Brancati Postoperative mortality in cancer patients with preexisting diabetes: systematic review and meta-analysis Diabetes Care 33 2010 931 939
-
(2010)
Diabetes Care
, vol.33
, pp. 931-939
-
-
Barone, B.B.1
Yeh, H.C.2
Snyder, C.F.3
Peairs, K.S.4
Stein, K.B.5
Derr, R.L.6
Wolff, A.C.7
Brancati, F.L.8
-
9
-
-
84864072013
-
Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis
-
K. Bhalla, B.J. Hwang, R.E. Dewi, W. Twaddel, O.G. Goloubeva, K.K. Wong, N.K. Saxena, S. Biswal, and G.D. Girnun Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis Cancer Prev. Res. (Phila) 5 2012 544 552
-
(2012)
Cancer Prev. Res. (Phila)
, vol.5
, pp. 544-552
-
-
Bhalla, K.1
Hwang, B.J.2
Dewi, R.E.3
Twaddel, W.4
Goloubeva, O.G.5
Wong, K.K.6
Saxena, N.K.7
Biswal, S.8
Girnun, G.D.9
-
10
-
-
84867404716
-
Metformin does not alter the risk of lung cancer: A case-control analysis
-
M. Bodmer, C. Becker, S.S. Jick, and C.R. Meier Metformin does not alter the risk of lung cancer: a case-control analysis Lung Cancer 78 2012 133 137
-
(2012)
Lung Cancer
, vol.78
, pp. 133-137
-
-
Bodmer, M.1
Becker, C.2
Jick, S.S.3
Meier, C.R.4
-
11
-
-
80054767295
-
Use of metformin and the risk of ovarian cancer: A case-control analysis
-
M. Bodmer, C. Becker, C. Meier, S.S. Jick, and C.R. Meier Use of metformin and the risk of ovarian cancer: a case-control analysis Gynecol. Oncol. 123 2011 200 204
-
(2011)
Gynecol. Oncol.
, vol.123
, pp. 200-204
-
-
Bodmer, M.1
Becker, C.2
Meier, C.3
Jick, S.S.4
Meier, C.R.5
-
12
-
-
84857073798
-
Use of metformin is not associated with a decreased risk of colorectal cancer: A case-control analysis
-
M. Bodmer, C. Becker, C. Meier, S.S. Jick, and C.R. Meier Use of metformin is not associated with a decreased risk of colorectal cancer: a case-control analysis Cancer Epidemiol. Biomarkers Prev. 21 2012 280 286
-
(2012)
Cancer Epidemiol. Biomarkers Prev.
, vol.21
, pp. 280-286
-
-
Bodmer, M.1
Becker, C.2
Meier, C.3
Jick, S.S.4
Meier, C.R.5
-
13
-
-
77953539812
-
Long-term metformin use is associated with decreased risk of breast cancer
-
M. Bodmer, C. Meier, S. Krahenbuhl, S.S. Jick, and C.R. Meier Long-term metformin use is associated with decreased risk of breast cancer Diabetes Care 33 2010 1304 1308
-
(2010)
Diabetes Care
, vol.33
, pp. 1304-1308
-
-
Bodmer, M.1
Meier, C.2
Krahenbuhl, S.3
Jick, S.S.4
Meier, C.R.5
-
14
-
-
84864075329
-
Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial
-
B. Bonanni, M. Puntoni, M. Cazzaniga, G. Pruneri, D. Serrano, A. Guerrieri-Gonzaga, A. Gennari, M.S. Trabacca, V. Galimberti, P. Veronesi, H. Johansson, V. Aristarco, F. Bassi, A. Luini, M. Lazzeroni, C. Varricchio, G. Viale, P. Bruzzi, and A. Decensi Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial J. Clin. Oncol. 30 2012 2593 2600
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 2593-2600
-
-
Bonanni, B.1
Puntoni, M.2
Cazzaniga, M.3
Pruneri, G.4
Serrano, D.5
Guerrieri-Gonzaga, A.6
Gennari, A.7
Trabacca, M.S.8
Galimberti, V.9
Veronesi, P.10
Johansson, H.11
Aristarco, V.12
Bassi, F.13
Luini, A.14
Lazzeroni, M.15
Varricchio, C.16
Viale, G.17
Bruzzi, P.18
Decensi, A.19
-
15
-
-
33645766204
-
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
-
S.L. Bowker, S.R. Majumdar, P. Veugelers, and J.A. Johnson Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin Diabetes Care 29 2006 254 258
-
(2006)
Diabetes Care
, vol.29
, pp. 254-258
-
-
Bowker, S.L.1
Majumdar, S.R.2
Veugelers, P.3
Johnson, J.A.4
-
16
-
-
84856423533
-
Risk of breast cancer after onset of type 2 diabetes: Evidence of detection bias in postmenopausal women
-
S.L. Bowker, K. Richardson, C.A. Marra, and J.A. Johnson Risk of breast cancer after onset of type 2 diabetes: evidence of detection bias in postmenopausal women Diabetes Care 34 2011 2542 2544
-
(2011)
Diabetes Care
, vol.34
, pp. 2542-2544
-
-
Bowker, S.L.1
Richardson, K.2
Marra, C.A.3
Johnson, J.A.4
-
17
-
-
84867899884
-
Diabetes and breast cancer risk: A meta-analysis
-
P. Boyle, M. Boniol, A. Koechlin, C. Robertson, F. Valentini, K. Coppens, L.L. Fairley, T. Zheng, Y. Zhang, M. Pasterk, M. Smans, M.P. Curado, P. Mullie, S. Gandini, M. Bota, G.B. Bolli, J. Rosenstock, and P. Autier Diabetes and breast cancer risk: a meta-analysis Br. J. Cancer 107 2012 1608 1617
-
(2012)
Br. J. Cancer
, vol.107
, pp. 1608-1617
-
-
Boyle, P.1
Boniol, M.2
Koechlin, A.3
Robertson, C.4
Valentini, F.5
Coppens, K.6
Fairley, L.L.7
Zheng, T.8
Zhang, Y.9
Pasterk, M.10
Smans, M.11
Curado, M.P.12
Mullie, P.13
Gandini, S.14
Bota, M.15
Bolli, G.B.16
Rosenstock, J.17
Autier, P.18
-
18
-
-
84865120793
-
Dorothy Hodgkin Lecture 2012: Non-alcoholic fatty liver disease, insulin resistance and ectopic fat: A new problem in diabetes management
-
C.D. Byrne Dorothy Hodgkin Lecture 2012: non-alcoholic fatty liver disease, insulin resistance and ectopic fat: a new problem in diabetes management Diabetic Med. 29 2012 1098 1107
-
(2012)
Diabetic Med.
, vol.29
, pp. 1098-1107
-
-
Byrne, C.D.1
-
19
-
-
70749106139
-
Metformin is a potent inhibitor of endometrial cancer cell proliferation - Implications for a novel treatment strategy
-
L.A. Cantrell, C. Zhou, A. Mendivil, K.M. Malloy, P.A. Gehrig, and V.L. Bae-Jump Metformin is a potent inhibitor of endometrial cancer cell proliferation - implications for a novel treatment strategy Gynecol. Oncol. 116 2010 92 98
-
(2010)
Gynecol. Oncol.
, vol.116
, pp. 92-98
-
-
Cantrell, L.A.1
Zhou, C.2
Mendivil, A.3
Malloy, K.M.4
Gehrig, P.A.5
Bae-Jump, V.L.6
-
20
-
-
0032835659
-
Further evidence for an association between non-insulin-dependent diabetes mellitus and chronic hepatitis C virus infection
-
S. Caronia, K. Taylor, L. Pagliaro, C. Carr, U. Palazzo, J. Petrik, S. O'Rahilly, S. Shore, B.D. Tom, and G.J. Alexander Further evidence for an association between non-insulin-dependent diabetes mellitus and chronic hepatitis C virus infection Hepatology 30 1999 1059 1063
-
(1999)
Hepatology
, vol.30
, pp. 1059-1063
-
-
Caronia, S.1
Taylor, K.2
Pagliaro, L.3
Carr, C.4
Palazzo, U.5
Petrik, J.6
O'Rahilly, S.7
Shore, S.8
Tom, B.D.9
Alexander, G.J.10
-
21
-
-
84862215222
-
Cancer occurrence in Danish diabetic patients: Duration and insulin effects
-
B. Carstensen, D.R. Witte, and S. Friis Cancer occurrence in Danish diabetic patients: duration and insulin effects Diabetologia 55 2012 948 958
-
(2012)
Diabetologia
, vol.55
, pp. 948-958
-
-
Carstensen, B.1
Witte, D.R.2
Friis, S.3
-
22
-
-
33646253204
-
Seroprevalence of hepatitis B and C in type 2 diabetic patients
-
H.F. Chen, C.Y. Li, P. Chen, T.T. See, and H.Y. Lee Seroprevalence of hepatitis B and C in type 2 diabetic patients J. Chin. Med. Assoc. 69 2006 146 152
-
(2006)
J. Chin. Med. Assoc.
, vol.69
, pp. 146-152
-
-
Chen, H.F.1
Li, C.Y.2
Chen, P.3
See, T.T.4
Lee, H.Y.5
-
23
-
-
84865084381
-
Diabetes, metformin, and breast cancer in postmenopausal women
-
R.T. Chlebowski, A. McTiernan, J. Wactawski-Wende, J.E. Manson, A.K. Aragaki, T. Rohan, E. Ipp, V.G. Kaklamani, M. Vitolins, R. Wallace, M. Gunter, L.S. Phillips, H. Strickler, K. Margolis, and D.M. Euhus Diabetes, metformin, and breast cancer in postmenopausal women J. Clin. Oncol. 30 2012 2844 2852
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 2844-2852
-
-
Chlebowski, R.T.1
McTiernan, A.2
Wactawski-Wende, J.3
Manson, J.E.4
Aragaki, A.K.5
Rohan, T.6
Ipp, E.7
Kaklamani, V.G.8
Vitolins, M.9
Wallace, R.10
Gunter, M.11
Phillips, L.S.12
Strickler, H.13
Margolis, K.14
Euhus, D.M.15
-
24
-
-
78649482632
-
Diabetes and cancer
-
T.A. Chowdhury Diabetes and cancer QJM 103 2010 905 915
-
(2010)
QJM
, vol.103
, pp. 905-915
-
-
Chowdhury, T.A.1
-
25
-
-
43049089327
-
Insulin therapy and colorectal adenoma risk among patients with Type 2 diabetes mellitus: A case-control study in Korea
-
Y.W. Chung, D.S. Han, K.H. Park, C.S. Eun, K.S. Yoo, and C.K. Park Insulin therapy and colorectal adenoma risk among patients with Type 2 diabetes mellitus: a case-control study in Korea Dis. Colon Rectum 51 2008 593 597
-
(2008)
Dis. Colon Rectum
, vol.51
, pp. 593-597
-
-
Chung, Y.W.1
Han, D.S.2
Park, K.H.3
Eun, C.S.4
Yoo, K.S.5
Park, C.K.6
-
26
-
-
84866548333
-
Metformin and breast cancer risk: A meta-analysis and critical literature review
-
N.F. Col, L. Ochs, V. Springmann, A.K. Aragaki, and R.T. Chlebowski Metformin and breast cancer risk: a meta-analysis and critical literature review Breast Cancer Res. Treat. 135 2012 639 646
-
(2012)
Breast Cancer Res. Treat.
, vol.135
, pp. 639-646
-
-
Col, N.F.1
Ochs, L.2
Springmann, V.3
Aragaki, A.K.4
Chlebowski, R.T.5
-
27
-
-
33746461855
-
Prevalence of diabetes and impaired fasting glucose in adults in the U.S. population: National Health and Nutrition Examination Survey 1999-2002
-
C.C. Cowie, K.F. Rust, D.D. Byrd-Holt, M.S. Eberhardt, K.M. Flegal, M.M. Engelgau, S.H. Saydah, D.E. Williams, L.S. Geiss, and E.W. Gregg Prevalence of diabetes and impaired fasting glucose in adults in the U.S. population: National Health and Nutrition Examination Survey 1999-2002 Diabetes Care 29 2006 1263 1268
-
(2006)
Diabetes Care
, vol.29
, pp. 1263-1268
-
-
Cowie, C.C.1
Rust, K.F.2
Byrd-Holt, D.D.3
Eberhardt, M.S.4
Flegal, K.M.5
Engelgau, M.M.6
Saydah, S.H.7
Williams, D.E.8
Geiss, L.S.9
Gregg, E.W.10
-
28
-
-
84864536555
-
Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts
-
S. Cufi, B. Corominas-Faja, A. Vazquez-Martin, C. Oliveras-Ferraros, J. Dorca, J. Bosch-Barrera, B. Martin-Castillo, and J.A. Menendez Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts Oncotarget 3 2012 395 398
-
(2012)
Oncotarget
, vol.3
, pp. 395-398
-
-
Cufi, S.1
Corominas-Faja, B.2
Vazquez-Martin, A.3
Oliveras-Ferraros, C.4
Dorca, J.5
Bosch-Barrera, J.6
Martin-Castillo, B.7
Menendez, J.A.8
-
29
-
-
68449094325
-
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
-
C.J. Currie, C.D. Poole, and E.A. Gale The influence of glucose-lowering therapies on cancer risk in type 2 diabetes Diabetologia 52 2009 1766 1777
-
(2009)
Diabetologia
, vol.52
, pp. 1766-1777
-
-
Currie, C.J.1
Poole, C.D.2
Gale, E.A.3
-
30
-
-
84859029647
-
Mortality after incident cancer in people with and without type 2 diabetes: Impact of metformin on survival
-
C.J. Currie, C.D. Poole, S. Jenkins-Jones, E.A. Gale, J.A. Johnson, and C.L. Morgan Mortality after incident cancer in people with and without type 2 diabetes: impact of metformin on survival Diabetes Care 35 2012 299 304
-
(2012)
Diabetes Care
, vol.35
, pp. 299-304
-
-
Currie, C.J.1
Poole, C.D.2
Jenkins-Jones, S.3
Gale, E.A.4
Johnson, J.A.5
Morgan, C.L.6
-
31
-
-
0029819936
-
Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus
-
K. Cusi, A. Consoli, and R.A. DeFronzo Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus J. Clin. Endocrinol. Metab. 81 1996 4059 4067
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 4059-4067
-
-
Cusi, K.1
Consoli, A.2
Defronzo, R.A.3
-
32
-
-
0033968126
-
Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle
-
K. Cusi, K. Maezono, A. Osman, M. Pendergrass, M.E. Patti, T. Pratipanawatr, R.A. DeFronzo, C.R. Kahn, and L.J. Mandarino Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle J. Clin. Invest. 105 2000 311 320
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 311-320
-
-
Cusi, K.1
Maezono, K.2
Osman, A.3
Pendergrass, M.4
Patti, M.E.5
Pratipanawatr, T.6
Defronzo, R.A.7
Kahn, C.R.8
Mandarino, L.J.9
-
33
-
-
77950516104
-
MTOR signaling and drug development in cancer
-
J. Dancey mTOR signaling and drug development in cancer Nat. Rev. Clin. Oncol. 7 2010 209 219
-
(2010)
Nat. Rev. Clin. Oncol.
, vol.7
, pp. 209-219
-
-
Dancey, J.1
-
34
-
-
0029561919
-
5′-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC
-
S.P. Davies, N.R. Helps, P.T. Cohen, and D.G. Hardie 5′-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC FEBS Lett. 377 1995 421 425
-
(1995)
FEBS Lett.
, vol.377
, pp. 421-425
-
-
Davies, S.P.1
Helps, N.R.2
Cohen, P.T.3
Hardie, D.G.4
-
35
-
-
15544382574
-
Diabetes increases the risk of hepatocellular carcinoma in the United States: A population based case control study
-
J.A. Davila, R.O. Morgan, Y. Shaib, K.A. McGlynn, and H.B. El-Serag Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study Gut 54 2005 533 539
-
(2005)
Gut
, vol.54
, pp. 533-539
-
-
Davila, J.A.1
Morgan, R.O.2
Shaib, Y.3
McGlynn, K.A.4
El-Serag, H.B.5
-
36
-
-
0029099086
-
Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group
-
R.A. DeFronzo, and A.M. Goodman Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group N. Engl. J. Med. 333 1995 541 549
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 541-549
-
-
Defronzo, R.A.1
Goodman, A.M.2
-
37
-
-
84859372038
-
Long-term safety, tolerability, and weight loss associated with metformin in the Diabetes Prevention Program Outcomes Study
-
Prevention Program Research Group D.
-
Diabetes Prevention Program Research Group Long-term safety, tolerability, and weight loss associated with metformin in the Diabetes Prevention Program Outcomes Study Diabetes Care 35 2012 731 737
-
(2012)
Diabetes Care
, vol.35
, pp. 731-737
-
-
-
38
-
-
77954365681
-
Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with chronic liver disease
-
V. Donadon, M. Balbi, M.D. Mas, P. Casarin, and G. Zanette Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with chronic liver disease Liver Int. 30 2010 750 758
-
(2010)
Liver Int.
, vol.30
, pp. 750-758
-
-
Donadon, V.1
Balbi, M.2
Mas, M.D.3
Casarin, P.4
Zanette, G.5
-
39
-
-
84864619407
-
Metformin sensitizes endometrial cancer cells to chemotherapy by repressing glyoxalase i expression
-
L. Dong, Q. Zhou, Z. Zhang, Y. Zhu, T. Duan, and Y. Feng Metformin sensitizes endometrial cancer cells to chemotherapy by repressing glyoxalase I expression J. Obstet. Gynaecol. Res. 38 2012 1077 1085
-
(2012)
J. Obstet. Gynaecol. Res.
, vol.38
, pp. 1077-1085
-
-
Dong, L.1
Zhou, Q.2
Zhang, Z.3
Zhu, Y.4
Duan, T.5
Feng, Y.6
-
41
-
-
36348950449
-
Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells
-
R.J. Dowling, M. Zakikhani, I.G. Fantus, M. Pollak, and N. Sonenberg Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells Cancer Res. 67 2007 10804 10812
-
(2007)
Cancer Res.
, vol.67
, pp. 10804-10812
-
-
Dowling, R.J.1
Zakikhani, M.2
Fantus, I.G.3
Pollak, M.4
Sonenberg, N.5
-
42
-
-
0034614420
-
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex i
-
M.Y. El-Mir, V. Nogueira, E. Fontaine, N. Averet, M. Rigoulet, and X. Leverve Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I J. Biol. Chem. 275 2000 223 228
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 223-228
-
-
El-Mir, M.Y.1
Nogueira, V.2
Fontaine, E.3
Averet, N.4
Rigoulet, M.5
Leverve, X.6
-
43
-
-
33644759114
-
The association between diabetes and hepatocellular carcinoma: A systematic review of epidemiologic evidence
-
H.B. El-Serag, H. Hampel, and F. Javadi The association between diabetes and hepatocellular carcinoma: a systematic review of epidemiologic evidence Clin. Gastroenterol. Hepatol. 4 2006 369 380
-
(2006)
Clin. Gastroenterol. Hepatol.
, vol.4
, pp. 369-380
-
-
El-Serag, H.B.1
Hampel, H.2
Javadi, F.3
-
45
-
-
0029017953
-
Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis
-
J. Everhart, and D. Wright Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis JAMA: J. Am. Med. Assoc. 273 1995 1605 1609
-
(1995)
JAMA: J. Am. Med. Assoc.
, vol.273
, pp. 1605-1609
-
-
Everhart, J.1
Wright, D.2
-
46
-
-
77954933558
-
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
-
M. Foretz, S. Hebrard, J. Leclerc, E. Zarrinpashneh, M. Soty, G. Mithieux, K. Sakamoto, F. Andreelli, and B. Viollet Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state J. Clin. Invest. 120 2010 2355 2369
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2355-2369
-
-
Foretz, M.1
Hebrard, S.2
Leclerc, J.3
Zarrinpashneh, E.4
Soty, M.5
Mithieux, G.6
Sakamoto, K.7
Andreelli, F.8
Viollet, B.9
-
47
-
-
47349101284
-
The role of insulin receptors and IGF-I receptors in cancer and other diseases
-
F. Frasca, G. Pandini, L. Sciacca, V. Pezzino, S. Squatrito, A. Belfiore, and R. Vigneri The role of insulin receptors and IGF-I receptors in cancer and other diseases Arch. Physiol. Biochem. 114 2008 23 37
-
(2008)
Arch. Physiol. Biochem.
, vol.114
, pp. 23-37
-
-
Frasca, F.1
Pandini, G.2
Sciacca, L.3
Pezzino, V.4
Squatrito, S.5
Belfiore, A.6
Vigneri, R.7
-
48
-
-
34249948987
-
Diabetes mellitus and risk of endometrial cancer: A meta-analysis
-
E. Friberg, N. Orsini, C.S. Mantzoros, and A. Wolk Diabetes mellitus and risk of endometrial cancer: a meta-analysis Diabetologia 50 2007 1365 1374
-
(2007)
Diabetologia
, vol.50
, pp. 1365-1374
-
-
Friberg, E.1
Orsini, N.2
Mantzoros, C.S.3
Wolk, A.4
-
49
-
-
84859631091
-
Survival advantage observed with the use of metformin in patients with type II diabetes and colorectal cancer
-
C.R. Garrett, H.M. Hassabo, N.A. Bhadkamkar, S. Wen, V. Baladandayuthapani, B.K. Kee, C. Eng, and M.M. Hassan Survival advantage observed with the use of metformin in patients with type II diabetes and colorectal cancer Br. J. Cancer 106 2012 1374 1378
-
(2012)
Br. J. Cancer
, vol.106
, pp. 1374-1378
-
-
Garrett, C.R.1
Hassabo, H.M.2
Bhadkamkar, N.A.3
Wen, S.4
Baladandayuthapani, V.5
Kee, B.K.6
Eng, C.7
Hassan, M.M.8
-
50
-
-
84865097800
-
Relation between diabetes, metformin treatment and the occurrence of malignancies in a Belgian primary care setting
-
N. Geraldine, A. Marc, T. Carla, M. Chantal, B. Stefaan, W. Welcome, and B. Frank Relation between diabetes, metformin treatment and the occurrence of malignancies in a Belgian primary care setting Diabetes Res. Clin. Pract. 97 2012 331 336
-
(2012)
Diabetes Res. Clin. Pract.
, vol.97
, pp. 331-336
-
-
Geraldine, N.1
Marc, A.2
Carla, T.3
Chantal, M.4
Stefaan, B.5
Welcome, W.6
Frank, B.7
-
51
-
-
77953846828
-
Diabetes and cancer: A consensus report
-
E. Giovannucci, D.M. Harlan, M.C. Archer, R.M. Bergenstal, S.M. Gapstur, L.A. Habel, M. Pollak, J.G. Regensteiner, and D. Yee Diabetes and cancer: a consensus report CA Cancer J. Clin. 60 2010 207 221
-
(2010)
CA Cancer J. Clin.
, vol.60
, pp. 207-221
-
-
Giovannucci, E.1
Harlan, D.M.2
Archer, M.C.3
Bergenstal, R.M.4
Gapstur, S.M.5
Habel, L.A.6
Pollak, M.7
Regensteiner, J.G.8
Yee, D.9
-
52
-
-
77949703788
-
Metformin: A therapeutic opportunity in breast cancer
-
A.M. Gonzalez-Angulo, and F. Meric-Bernstam Metformin: a therapeutic opportunity in breast cancer Clin. Cancer Res. 16 2010 1695 1700
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 1695-1700
-
-
Gonzalez-Angulo, A.M.1
Meric-Bernstam, F.2
-
53
-
-
79151478459
-
Evaluation of metformin in early breast cancer: A modification of the traditional paradigm for clinical testing of anti-cancer agents
-
P.J. Goodwin, V. Stambolic, J. Lemieux, B.E. Chen, W.R. Parulekar, K.A. Gelmon, D.L. Hershman, T.J. Hobday, J.A. Ligibel, I.A. Mayer, K.I. Pritchard, T.J. Whelan, P. Rastogi, and L.E. Shepherd Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents Breast Cancer Res. Treat. 126 2011 215 220
-
(2011)
Breast Cancer Res. Treat.
, vol.126
, pp. 215-220
-
-
Goodwin, P.J.1
Stambolic, V.2
Lemieux, J.3
Chen, B.E.4
Parulekar, W.R.5
Gelmon, K.A.6
Hershman, D.L.7
Hobday, T.J.8
Ligibel, J.A.9
Mayer, I.A.10
Pritchard, K.I.11
Whelan, T.J.12
Rastogi, P.13
Shepherd, L.E.14
-
54
-
-
78549283186
-
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation
-
A.S. Green, N. Chapuis, T.T. Maciel, L. Willems, M. Lambert, C. Arnoult, O. Boyer, V. Bardet, S. Park, M. Foretz, B. Viollet, N. Ifrah, F. Dreyfus, O. Hermine, I.C. Moura, C. Lacombe, P. Mayeux, D. Bouscary, and J. Tamburini The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation Blood 116 2010 4262 4273
-
(2010)
Blood
, vol.116
, pp. 4262-4273
-
-
Green, A.S.1
Chapuis, N.2
Maciel, T.T.3
Willems, L.4
Lambert, M.5
Arnoult, C.6
Boyer, O.7
Bardet, V.8
Park, S.9
Foretz, M.10
Viollet, B.11
Ifrah, N.12
Dreyfus, F.13
Hermine, O.14
Moura, I.C.15
Lacombe, C.16
Mayeux, P.17
Bouscary, D.18
Tamburini, J.19
-
55
-
-
79959455071
-
Anticancer effects of metformin and its potential use as a therapeutic agent for breast cancer
-
A. Guppy, M. Jamal-Hanjani, and L. Pickering Anticancer effects of metformin and its potential use as a therapeutic agent for breast cancer Future Oncol. 7 2011 727 736
-
(2011)
Future Oncol.
, vol.7
, pp. 727-736
-
-
Guppy, A.1
Jamal-Hanjani, M.2
Pickering, L.3
-
56
-
-
79960845901
-
Evidence for biological effects of metformin in operable breast cancer: A pre-operative, window-of-opportunity, randomized trial
-
S. Hadad, T. Iwamoto, L. Jordan, C. Purdie, S. Bray, L. Baker, G. Jellema, S. Deharo, D.G. Hardie, L. Pusztai, S. Moulder-Thompson, J.A. Dewar, and A.M. Thompson Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial Breast Cancer Res. Treat. 128 2011 783 794
-
(2011)
Breast Cancer Res. Treat.
, vol.128
, pp. 783-794
-
-
Hadad, S.1
Iwamoto, T.2
Jordan, L.3
Purdie, C.4
Bray, S.5
Baker, L.6
Jellema, G.7
Deharo, S.8
Hardie, D.G.9
Pusztai, L.10
Moulder-Thompson, S.11
Dewar, J.A.12
Thompson, A.M.13
-
57
-
-
84858745832
-
Metformin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and modulation of the mTOR pathway
-
R.K. Hanna, C. Zhou, K.M. Malloy, L. Sun, Y. Zhong, P.A. Gehrig, and V.L. Bae-Jump Metformin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and modulation of the mTOR pathway Gynecol. Oncol. 125 2012 458 469
-
(2012)
Gynecol. Oncol.
, vol.125
, pp. 458-469
-
-
Hanna, R.K.1
Zhou, C.2
Malloy, K.M.3
Sun, L.4
Zhong, Y.5
Gehrig, P.A.6
Bae-Jump, V.L.7
-
58
-
-
10944247187
-
The AMP-activated protein kinase pathway - New players upstream and downstream
-
D.G. Hardie The AMP-activated protein kinase pathway - new players upstream and downstream J. Cell Sci. 117 2004 5479 5487
-
(2004)
J. Cell Sci.
, vol.117
, pp. 5479-5487
-
-
Hardie, D.G.1
-
59
-
-
0031897103
-
Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994
-
M.I. Harris, K.M. Flegal, C.C. Cowie, M.S. Eberhardt, D.E. Goldstein, R.R. Little, H.M. Wiedmeyer, and D.D. Byrd-Holt Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994 Diabetes Care 21 1998 518 524
-
(1998)
Diabetes Care
, vol.21
, pp. 518-524
-
-
Harris, M.I.1
Flegal, K.M.2
Cowie, C.C.3
Eberhardt, M.S.4
Goldstein, D.E.5
Little, R.R.6
Wiedmeyer, H.M.7
Byrd-Holt, D.D.8
-
60
-
-
16544389644
-
The chemical pathology of insulin resistance and the metabolic syndrome
-
N.S. Harris, and W.E. Winter The chemical pathology of insulin resistance and the metabolic syndrome MLO: Med. Lab. Obs. 36 20 2004 22 25
-
(2004)
MLO: Med. Lab. Obs.
, vol.36
, Issue.20
, pp. 22-25
-
-
Harris, N.S.1
Winter, W.E.2
-
61
-
-
77951006620
-
Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma
-
M.M. Hassan, S.A. Curley, D. Li, A. Kaseb, M. Davila, E.K. Abdalla, M. Javle, D.M. Moghazy, R.D. Lozano, J.L. Abbruzzese, and J.N. Vauthey Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma Cancer 116 2010 1938 1946
-
(2010)
Cancer
, vol.116
, pp. 1938-1946
-
-
Hassan, M.M.1
Curley, S.A.2
Li, D.3
Kaseb, A.4
Davila, M.5
Abdalla, E.K.6
Javle, M.7
Moghazy, D.M.8
Lozano, R.D.9
Abbruzzese, J.L.10
Vauthey, J.N.11
-
62
-
-
0029910018
-
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
-
S.A. Hawley, M. Davison, A. Woods, S.P. Davies, R.K. Beri, D. Carling, and D.G. Hardie Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase J. Biol. Chem. 271 1996 27879 27887
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27879-27887
-
-
Hawley, S.A.1
Davison, M.2
Woods, A.3
Davies, S.P.4
Beri, R.K.5
Carling, D.6
Hardie, D.G.7
-
63
-
-
84864314304
-
Metformin and thiazolidinediones are associated with improved breast cancer-specific survival of diabetic women with HER2+ breast cancer
-
X. He, F.J. Esteva, J. Ensor, G.N. Hortobagyi, M.H. Lee, and S.C. Yeung Metformin and thiazolidinediones are associated with improved breast cancer-specific survival of diabetic women with HER2+ breast cancer Ann. Oncol. 23 2012 1771 1780
-
(2012)
Ann. Oncol.
, vol.23
, pp. 1771-1780
-
-
He, X.1
Esteva, F.J.2
Ensor, J.3
Hortobagyi, G.N.4
Lee, M.H.5
Yeung, S.C.6
-
64
-
-
84858729797
-
Metformin efficacy and safety for colorectal polyps: A double-blind randomized controlled trial
-
T. Higurashi, H. Takahashi, H. Endo, K. Hosono, E. Yamada, H. Ohkubo, E. Sakai, T. Uchiyama, Y. Hata, N. Fujisawa, S. Uchiyama, A. Ezuka, H. Nagase, T. Kessoku, N. Matsuhashi, S. Yamanaka, Y. Inayama, S. Morita, and A. Nakajima Metformin efficacy and safety for colorectal polyps: a double-blind randomized controlled trial BMC Cancer 12 2012 118
-
(2012)
BMC Cancer
, vol.12
, pp. 118
-
-
Higurashi, T.1
Takahashi, H.2
Endo, H.3
Hosono, K.4
Yamada, E.5
Ohkubo, H.6
Sakai, E.7
Uchiyama, T.8
Hata, Y.9
Fujisawa, N.10
Uchiyama, S.11
Ezuka, A.12
Nagase, H.13
Kessoku, T.14
Matsuhashi, N.15
Yamanaka, S.16
Inayama, Y.17
Morita, S.18
Nakajima, A.19
-
65
-
-
55949116238
-
Evaluating the evidence: Is there a rigid hierarchy?
-
P.M. Ho, P.N. Peterson, and F.A. Masoudi Evaluating the evidence: is there a rigid hierarchy? Circulation 118 2008 1675 1684
-
(2008)
Circulation
, vol.118
, pp. 1675-1684
-
-
Ho, P.M.1
Peterson, P.N.2
Masoudi, F.A.3
-
66
-
-
77956411030
-
Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial
-
K. Hosono, H. Endo, H. Takahashi, M. Sugiyama, E. Sakai, T. Uchiyama, K. Suzuki, H. Iida, Y. Sakamoto, K. Yoneda, T. Koide, C. Tokoro, Y. Abe, M. Inamori, H. Nakagama, and A. Nakajima Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial Cancer Prev. Res. (Phila) 3 2010 1077 1083
-
(2010)
Cancer Prev. Res. (Phila)
, vol.3
, pp. 1077-1083
-
-
Hosono, K.1
Endo, H.2
Takahashi, H.3
Sugiyama, M.4
Sakai, E.5
Uchiyama, T.6
Suzuki, K.7
Iida, H.8
Sakamoto, Y.9
Yoneda, K.10
Koide, T.11
Tokoro, C.12
Abe, Y.13
Inamori, M.14
Nakagama, H.15
Nakajima, A.16
-
67
-
-
84861945853
-
Metformin induces differentiation in acute promyelocytic leukemia by activating the MEK/ERK signaling pathway
-
L. Huai, C. Wang, C. Zhang, Q. Li, Y. Chen, Y. Jia, Y. Li, H. Xing, Z. Tian, Q. Rao, M. Wang, and J. Wang Metformin induces differentiation in acute promyelocytic leukemia by activating the MEK/ERK signaling pathway Biochem. Biophys. Res. Commun. 422 2012 398 404
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.422
, pp. 398-404
-
-
Huai, L.1
Wang, C.2
Zhang, C.3
Li, Q.4
Chen, Y.5
Jia, Y.6
Li, Y.7
Xing, H.8
Tian, Z.9
Rao, Q.10
Wang, M.11
Wang, J.12
-
68
-
-
0642333879
-
Increased incidence of coronary atherosclerosis in type 2 diabetes mellitus: Mechanisms and management
-
R.T. Hurst, and R.W. Lee Increased incidence of coronary atherosclerosis in type 2 diabetes mellitus: mechanisms and management Ann. Intern. Med. 139 2003 824 834
-
(2003)
Ann. Intern. Med.
, vol.139
, pp. 824-834
-
-
Hurst, R.T.1
Lee, R.W.2
-
69
-
-
0033952266
-
Inhibitory effect of metformin on intestinal glucose absorption in the perfused rat intestine
-
T. Ikeda, K. Iwata, and H. Murakami Inhibitory effect of metformin on intestinal glucose absorption in the perfused rat intestine Biochem. Pharmacol. 59 2000 887 890
-
(2000)
Biochem. Pharmacol.
, vol.59
, pp. 887-890
-
-
Ikeda, T.1
Iwata, K.2
Murakami, H.3
-
70
-
-
79955490053
-
Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types
-
D. Iliopoulos, H.A. Hirsch, and K. Struhl Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types Cancer Res. 71 2011 3196 3201
-
(2011)
Cancer Res.
, vol.71
, pp. 3196-3201
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
71
-
-
0032719024
-
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
-
Z.Y. Jiang, Y.W. Lin, A. Clemont, E.P. Feener, K.D. Hein, M. Igarashi, T. Yamauchi, M.F. White, and G.L. King Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats J. Clin. Invest. 104 1999 447 457
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 447-457
-
-
Jiang, Z.Y.1
Lin, Y.W.2
Clemont, A.3
Feener, E.P.4
Hein, K.D.5
Igarashi, M.6
Yamauchi, T.7
White, M.F.8
King, G.L.9
-
72
-
-
77955287742
-
Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner
-
A. Kalender, A. Selvaraj, S.Y. Kim, P. Gulati, S. Brule, B. Viollet, B.E. Kemp, N. Bardeesy, P. Dennis, J.J. Schlager, A. Marette, S.C. Kozma, and G. Thomas Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner Cell Metab. 11 2010 390 401
-
(2010)
Cell Metab.
, vol.11
, pp. 390-401
-
-
Kalender, A.1
Selvaraj, A.2
Kim, S.Y.3
Gulati, P.4
Brule, S.5
Viollet, B.6
Kemp, B.E.7
Bardeesy, N.8
Dennis, P.9
Schlager, J.J.10
Marette, A.11
Kozma, S.C.12
Thomas, G.13
-
73
-
-
33845328853
-
A meta-analysis of diabetes mellitus and the risk of prostate cancer
-
J.S. Kasper, and E. Giovannucci A meta-analysis of diabetes mellitus and the risk of prostate cancer Cancer Epidemiol. Biomarkers Prev. 15 2006 2056 2062
-
(2006)
Cancer Epidemiol. Biomarkers Prev.
, vol.15
, pp. 2056-2062
-
-
Kasper, J.S.1
Giovannucci, E.2
-
74
-
-
84859386824
-
The antidiabetic drug metformin inhibits gastric cancer cell proliferation in vitro and in vivo
-
K. Kato, J. Gong, H. Iwama, A. Kitanaka, J. Tani, H. Miyoshi, K. Nomura, S. Mimura, M. Kobayashi, Y. Aritomo, H. Kobara, H. Mori, T. Himoto, K. Okano, Y. Suzuki, K. Murao, and T. Masaki The antidiabetic drug metformin inhibits gastric cancer cell proliferation in vitro and in vivo Mol. Cancer Ther. 11 2012 549 560
-
(2012)
Mol. Cancer Ther.
, vol.11
, pp. 549-560
-
-
Kato, K.1
Gong, J.2
Iwama, H.3
Kitanaka, A.4
Tani, J.5
Miyoshi, H.6
Nomura, K.7
Mimura, S.8
Kobayashi, M.9
Aritomo, Y.10
Kobara, H.11
Mori, H.12
Himoto, T.13
Okano, K.14
Suzuki, Y.15
Murao, K.16
Masaki, T.17
-
75
-
-
0031752685
-
Global burden of diabetes, 1995-2025: Prevalence, numerical estimates, and projections
-
H. King, R.E. Aubert, and W.H. Herman Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections Diabetes Care 21 1998 1414 1431
-
(1998)
Diabetes Care
, vol.21
, pp. 1414-1431
-
-
King, H.1
Aubert, R.E.2
Herman, W.H.3
-
76
-
-
84862684484
-
Metformin inhibits growth and decreases resistance to anoikis in medullary thyroid cancer cells
-
J. Klubo-Gwiezdzinska, K. Jensen, J. Costello, A. Patel, V. Hoperia, A. Bauer, K.D. Burman, L. Wartofsky, and V. Vasko Metformin inhibits growth and decreases resistance to anoikis in medullary thyroid cancer cells Endocrinol. Relat. Cancer 19 2012 447 456
-
(2012)
Endocrinol. Relat. Cancer
, vol.19
, pp. 447-456
-
-
Klubo-Gwiezdzinska, J.1
Jensen, K.2
Costello, J.3
Patel, A.4
Hoperia, V.5
Bauer, A.6
Burman, K.D.7
Wartofsky, L.8
Vasko, V.9
-
78
-
-
70449517253
-
10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study
-
W.C. Knowler, S.E. Fowler, R.F. Hamman, C.A. Christophi, H.J. Hoffman, A.T. Brenneman, J.O. Brown-Friday, R. Goldberg, E. Venditti, and D.M. Nathan 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study Lancet 374 2009 1677 1686
-
(2009)
Lancet
, vol.374
, pp. 1677-1686
-
-
Knowler, W.C.1
Fowler, S.E.2
Hamman, R.F.3
Christophi, C.A.4
Hoffman, H.J.5
Brenneman, A.T.6
Brown-Friday, J.O.7
Goldberg, R.8
Venditti, E.9
Nathan, D.M.10
-
79
-
-
84855432249
-
Risk of hepatocellular carcinoma in diabetic patients and risk reduction associated with anti-diabetic therapy: A population-based cohort study
-
S.W. Lai, P.C. Chen, K.F. Liao, C.H. Muo, C.C. Lin, and F.C. Sung Risk of hepatocellular carcinoma in diabetic patients and risk reduction associated with anti-diabetic therapy: a population-based cohort study Am. J. Gastroenterol. 107 2012 46 52
-
(2012)
Am. J. Gastroenterol.
, vol.107
, pp. 46-52
-
-
Lai, S.W.1
Chen, P.C.2
Liao, K.F.3
Muo, C.H.4
Lin, C.C.5
Sung, F.C.6
-
80
-
-
84863116107
-
Antidiabetes drugs correlate with decreased risk of lung cancer: A population-based observation in Taiwan
-
S.W. Lai, K.F. Liao, P.C. Chen, P.Y. Tsai, D.P. Hsieh, and C.C. Chen Antidiabetes drugs correlate with decreased risk of lung cancer: a population-based observation in Taiwan Clin Lung Cancer 13 2012 143 148
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 143-148
-
-
Lai, S.W.1
Liao, K.F.2
Chen, P.C.3
Tsai, P.Y.4
Hsieh, D.P.5
Chen, C.C.6
-
81
-
-
75149179169
-
Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16
-
G.W. Landman, N. Kleefstra, K.J. van Hateren, K.H. Groenier, R.O. Gans, and H.J. Bilo Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16 Diabetes Care 33 2010 322 326
-
(2010)
Diabetes Care
, vol.33
, pp. 322-326
-
-
Landman, G.W.1
Kleefstra, N.2
Van Hateren, K.J.3
Groenier, K.H.4
Gans, R.O.5
Bilo, H.J.6
-
82
-
-
27944450832
-
Diabetes mellitus and risk of colorectal cancer: A meta-analysis
-
S.C. Larsson, N. Orsini, and A. Wolk Diabetes mellitus and risk of colorectal cancer: a meta-analysis J. Nat. Cancer Inst. 97 2005 1679 1687
-
(2005)
J. Nat. Cancer Inst.
, vol.97
, pp. 1679-1687
-
-
Larsson, S.C.1
Orsini, N.2
Wolk, A.3
-
83
-
-
79954631858
-
Diabetes mellitus and incidence of kidney cancer: A meta-analysis of cohort studies
-
S.C. Larsson, and A. Wolk Diabetes mellitus and incidence of kidney cancer: a meta-analysis of cohort studies Diabetologia 54 2011 1013 1018
-
(2011)
Diabetologia
, vol.54
, pp. 1013-1018
-
-
Larsson, S.C.1
Wolk, A.2
-
84
-
-
78651451726
-
Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: A representative population prospective cohort study of 800,000 individuals
-
M.S. Lee, C.C. Hsu, M.L. Wahlqvist, H.N. Tsai, Y.H. Chang, and Y.C. Huang Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals BMC Cancer 11 2011 20
-
(2011)
BMC Cancer
, vol.11
, pp. 20
-
-
Lee, M.S.1
Hsu, C.C.2
Wahlqvist, M.L.3
Tsai, H.N.4
Chang, Y.H.5
Huang, Y.C.6
-
85
-
-
84862064131
-
Statin use as a moderator of metformin effect on risk for prostate cancer among type 2 diabetic patients
-
D.M. Lehman, C. Lorenzo, J. Hernandez, and C.P. Wang Statin use as a moderator of metformin effect on risk for prostate cancer among type 2 diabetic patients Diabetes Care 35 2012 1002 1007
-
(2012)
Diabetes Care
, vol.35
, pp. 1002-1007
-
-
Lehman, D.M.1
Lorenzo, C.2
Hernandez, J.3
Wang, C.P.4
-
86
-
-
36249024158
-
Medical therapy for diabetes is associated with increased use of lower endoscopy
-
J.D. Lewis, A.M. Capra, N.S. Achacoso, A. Ferrara, T.R. Levin, C.P. Quesenberry Jr., and L.A. Habel Medical therapy for diabetes is associated with increased use of lower endoscopy Pharmacoepidemiol. Drug Saf. 16 2007 1195 1202
-
(2007)
Pharmacoepidemiol. Drug Saf.
, vol.16
, pp. 1195-1202
-
-
Lewis, J.D.1
Capra, A.M.2
Achacoso, N.S.3
Ferrara, A.4
Levin, T.R.5
Quesenberry, Jr.C.P.6
Habel, L.A.7
-
87
-
-
84863011300
-
Association between diabetes mellitus and breast cancer risk: A meta-analysis of the literature
-
S. Liao, J. Li, W. Wei, L. Wang, Y. Zhang, C. Wang, and S. Sun Association between diabetes mellitus and breast cancer risk: a meta-analysis of the literature Asian Pac. J. Cancer Prev. 12 2011 1061 1065
-
(2011)
Asian Pac. J. Cancer Prev.
, vol.12
, pp. 1061-1065
-
-
Liao, S.1
Li, J.2
Wei, W.3
Wang, L.4
Zhang, Y.5
Wang, C.6
Sun, S.7
-
88
-
-
69549097703
-
New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
-
G. Libby, L.A. Donnelly, P.T. Donnan, D.R. Alessi, A.D. Morris, and J.M. Evans New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes Diabetes Care 32 2009 1620 1625
-
(2009)
Diabetes Care
, vol.32
, pp. 1620-1625
-
-
Libby, G.1
Donnelly, L.A.2
Donnan, P.T.3
Alessi, D.R.4
Morris, A.D.5
Evans, J.M.6
-
89
-
-
43149101289
-
The impact of diabetes on survival following breast cancer
-
L.L. Lipscombe, P.J. Goodwin, B. Zinman, J.R. McLaughlin, and J.E. Hux The impact of diabetes on survival following breast cancer Breast Cancer Res. Treat. 109 2008 389 395
-
(2008)
Breast Cancer Res. Treat.
, vol.109
, pp. 389-395
-
-
Lipscombe, L.L.1
Goodwin, P.J.2
Zinman, B.3
McLaughlin, J.R.4
Hux, J.E.5
-
90
-
-
33847303686
-
Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995-2005: A population-based study
-
L.L. Lipscombe, and J.E. Hux Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995-2005: a population-based study Lancet 369 2007 750 756
-
(2007)
Lancet
, vol.369
, pp. 750-756
-
-
Lipscombe, L.L.1
Hux, J.E.2
-
91
-
-
84861487778
-
Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro
-
H. Liu, C. Scholz, C. Zang, J.H. Schefe, P. Habbel, A.C. Regierer, C.O. Schulz, K. Possinger, and J. Eucker Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro Anticancer Res. 32 2012 1627 1637
-
(2012)
Anticancer Res.
, vol.32
, pp. 1627-1637
-
-
Liu, H.1
Scholz, C.2
Zang, C.3
Schefe, J.H.4
Habbel, P.5
Regierer, A.C.6
Schulz, C.O.7
Possinger, K.8
Eucker, J.9
-
92
-
-
67649105708
-
Hepatitis C and diabetes: The inevitable coincidence?
-
A. Lonardo, L.E. Adinolfi, S. Petta, A. Craxi, and P. Loria Hepatitis C and diabetes: the inevitable coincidence? Expert Rev. Anti Infect. Ther. 7 2009 293 308
-
(2009)
Expert Rev. Anti Infect. Ther.
, vol.7
, pp. 293-308
-
-
Lonardo, A.1
Adinolfi, L.E.2
Petta, S.3
Craxi, A.4
Loria, P.5
-
93
-
-
54349083481
-
Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: A long-term survival analysis
-
J. Ma, H. Li, E. Giovannucci, L. Mucci, W. Qiu, P.L. Nguyen, J.M. Gaziano, M. Pollak, and M.J. Stampfer Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis Lancet Oncol. 9 2008 1039 1047
-
(2008)
Lancet Oncol.
, vol.9
, pp. 1039-1047
-
-
Ma, J.1
Li, H.2
Giovannucci, E.3
Mucci, L.4
Qiu, W.5
Nguyen, P.L.6
Gaziano, J.M.7
Pollak, M.8
Stampfer, M.J.9
-
94
-
-
79952856558
-
Diabetes and risk of bladder cancer: Evidence from a case-control study in New England
-
T. MacKenzie, M.S. Zens, A. Ferrara, A. Schned, and M.R. Karagas Diabetes and risk of bladder cancer: evidence from a case-control study in New England Cancer 117 2011 1552 1556
-
(2011)
Cancer
, vol.117
, pp. 1552-1556
-
-
Mackenzie, T.1
Zens, M.S.2
Ferrara, A.3
Schned, A.4
Karagas, M.R.5
-
95
-
-
84866156935
-
The effect of metformin and thiazolidinedione use on lung cancer in diabetics
-
P.J. Mazzone, H. Rai, M. Beukemann, M. Xu, A.K. Jain, and M. Sasidhar The effect of metformin and thiazolidinedione use on lung cancer in diabetics BMC Cancer 12 2012 410
-
(2012)
BMC Cancer
, vol.12
, pp. 410
-
-
Mazzone, P.J.1
Rai, H.2
Beukemann, M.3
Xu, M.4
Jain, A.K.5
Sasidhar, M.6
-
96
-
-
73349087844
-
LKB1 and mammalian target of rapamycin as predictive factors for the anticancer efficacy of metformin
-
e226; author reply e227
-
R.M. Memmott, and P.A. Dennis LKB1 and mammalian target of rapamycin as predictive factors for the anticancer efficacy of metformin J. Clin. Oncol. 27 2009 e226; author reply e227
-
(2009)
J. Clin. Oncol.
, vol.27
-
-
Memmott, R.M.1
Dennis, P.A.2
-
97
-
-
34748912615
-
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
-
J.A. Menendez, and R. Lupu Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis Nat. Rev. Cancer 7 2007 763 777
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 763-777
-
-
Menendez, J.A.1
Lupu, R.2
-
98
-
-
0037313036
-
Impact of diabetes mellitus on outcomes in patients with colon cancer
-
J.A. Meyerhardt, P.J. Catalano, D.G. Haller, R.J. Mayer, J.S. Macdonald, A.B. Benson 3rd, and C.S. Fuchs Impact of diabetes mellitus on outcomes in patients with colon cancer J. Clin. Oncol. 21 2003 433 440
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 433-440
-
-
Meyerhardt, J.A.1
Catalano, P.J.2
Haller, D.G.3
Mayer, R.J.4
Macdonald, J.S.5
Benson III, A.B.6
Fuchs, C.S.7
-
99
-
-
0041668140
-
Type 2 diabetes and subsequent incidence of breast cancer in the Nurses' Health Study
-
K.B. Michels, C.G. Solomon, F.B. Hu, B.A. Rosner, S.E. Hankinson, G.A. Colditz, and J.E. Manson Type 2 diabetes and subsequent incidence of breast cancer in the Nurses' Health Study Diabetes Care 26 2003 1752 1758
-
(2003)
Diabetes Care
, vol.26
, pp. 1752-1758
-
-
Michels, K.B.1
Solomon, C.G.2
Hu, F.B.3
Rosner, B.A.4
Hankinson, S.E.5
Colditz, G.A.6
Manson, J.E.7
-
100
-
-
0036517099
-
Dose-response effect of pioglitazone on insulin sensitivity and insulin secretion in type 2 diabetes
-
Y. Miyazaki, M. Matsuda, and R.A. DeFronzo Dose-response effect of pioglitazone on insulin sensitivity and insulin secretion in type 2 diabetes Diabetes Care 25 2002 517 523
-
(2002)
Diabetes Care
, vol.25
, pp. 517-523
-
-
Miyazaki, Y.1
Matsuda, M.2
Defronzo, R.A.3
-
101
-
-
84866538325
-
Metformin in early breast cancer: A prospective window of opportunity neoadjuvant study
-
S. Niraula, R.J. Dowling, M. Ennis, M.C. Chang, S.J. Done, N. Hood, J. Escallon, W.L. Leong, D.R. McCready, M. Reedijk, V. Stambolic, and P.J. Goodwin Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study Breast Cancer Res. Treat. 135 2012 821 830
-
(2012)
Breast Cancer Res. Treat.
, vol.135
, pp. 821-830
-
-
Niraula, S.1
Dowling, R.J.2
Ennis, M.3
Chang, M.C.4
Done, S.J.5
Hood, N.6
Escallon, J.7
Leong, W.L.8
McCready, D.R.9
Reedijk, M.10
Stambolic, V.11
Goodwin, P.J.12
-
102
-
-
79961216168
-
Impact of metformin on the prognosis of cirrhosis induced by viral hepatitis C in diabetic patients
-
G. Nkontchou, E. Cosson, M. Aout, A. Mahmoudi, V. Bourcier, I. Charif, N. Ganne-Carrie, V. Grando-Lemaire, E. Vicaut, J.C. Trinchet, and M. Beaugrand Impact of metformin on the prognosis of cirrhosis induced by viral hepatitis C in diabetic patients J. Clin. Endocrinol. Metab. 96 2011 2601 2608
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. 2601-2608
-
-
Nkontchou, G.1
Cosson, E.2
Aout, M.3
Mahmoudi, A.4
Bourcier, V.5
Charif, I.6
Ganne-Carrie, N.7
Grando-Lemaire, V.8
Vicaut, E.9
Trinchet, J.C.10
Beaugrand, M.11
-
103
-
-
31344452199
-
Meta-analysis: Methods, strengths, weaknesses, and political uses
-
J.H. Noble Jr. Meta-analysis: methods, strengths, weaknesses, and political uses J. Lab. Clin. Med. 147 2006 7 20
-
(2006)
J. Lab. Clin. Med.
, vol.147
, pp. 7-20
-
-
Noble, Jr.J.H.1
-
104
-
-
84858695046
-
Cancer risk in diabetic patients treated with metformin: A systematic review and meta-analysis
-
H. Noto, A. Goto, T. Tsujimoto, and M. Noda Cancer risk in diabetic patients treated with metformin: a systematic review and meta-analysis PLoS One 7 2012 e33411
-
(2012)
PLoS One
, vol.7
, pp. 33411
-
-
Noto, H.1
Goto, A.2
Tsujimoto, T.3
Noda, M.4
-
105
-
-
78651335893
-
Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs
-
T. Okumura Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs J. Gastroenterol. 45 2010 1097 1102
-
(2010)
J. Gastroenterol.
, vol.45
, pp. 1097-1102
-
-
Okumura, T.1
-
106
-
-
84255168020
-
Diabetes mellitus and the risk of cancer
-
A. Pandey, V. Forte, M. Abdallah, A. Alickaj, S. Mahmud, S. Asad, and S.I. McFarlane Diabetes mellitus and the risk of cancer Minerva Endocrinol. 36 2011 187 209
-
(2011)
Minerva Endocrinol.
, vol.36
, pp. 187-209
-
-
Pandey, A.1
Forte, V.2
Abdallah, M.3
Alickaj, A.4
Mahmud, S.5
Asad, S.6
McFarlane, S.I.7
-
107
-
-
47349117519
-
Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies
-
P. Pisani Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies Arch. Physiol. Biochem. 114 2008 63 70
-
(2008)
Arch. Physiol. Biochem.
, vol.114
, pp. 63-70
-
-
Pisani, P.1
-
108
-
-
56749184290
-
Insulin and insulin-like growth factor signalling in neoplasia
-
M. Pollak Insulin and insulin-like growth factor signalling in neoplasia Nat. Rev. Cancer 8 2008 915 928
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 915-928
-
-
Pollak, M.1
-
109
-
-
84857640868
-
The insulin and insulin-like growth factor receptor family in neoplasia: An update
-
M. Pollak The insulin and insulin-like growth factor receptor family in neoplasia: an update Nat. Rev. Cancer 12 2012 159 169
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 159-169
-
-
Pollak, M.1
-
110
-
-
84866322945
-
Investigating metformin for cancer prevention and treatment: The end of the beginning
-
M.N. Pollak Investigating metformin for cancer prevention and treatment: the end of the beginning Cancer Discov. 2 2012 778 790
-
(2012)
Cancer Discov.
, vol.2
, pp. 778-790
-
-
Pollak, M.N.1
-
111
-
-
62749188867
-
The role of the lipogenic pathway in the development of hepatic steatosis
-
C. Postic, and J. Girard The role of the lipogenic pathway in the development of hepatic steatosis Diabetes Metab. 34 2008 643 648
-
(2008)
Diabetes Metab.
, vol.34
, pp. 643-648
-
-
Postic, C.1
Girard, J.2
-
112
-
-
84865131639
-
In vitro and in vivo antitumoral action of metformin on hepatocellular carcinoma
-
Z. Qu, Y. Zhang, M. Liao, Y. Chen, J. Zhao, and Y. Pan In vitro and in vivo antitumoral action of metformin on hepatocellular carcinoma Hepatol. Res. Off. J. Jpn. Soc. Hepatol. 42 2012 922 933
-
(2012)
Hepatol. Res. Off. J. Jpn. Soc. Hepatol.
, vol.42
, pp. 922-933
-
-
Qu, Z.1
Zhang, Y.2
Liao, M.3
Chen, Y.4
Zhao, J.5
Pan, Y.6
-
113
-
-
79955834631
-
Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo
-
R. Rattan, R.P. Graham, J.L. Maguire, S. Giri, and V. Shridhar Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo Neoplasia 13 2011 483 491
-
(2011)
Neoplasia
, vol.13
, pp. 483-491
-
-
Rattan, R.1
Graham, R.P.2
Maguire, J.L.3
Giri, S.4
Shridhar, V.5
-
114
-
-
84873144487
-
Increased risk of acute hepatitis B among adults with diagnosed diabetes mellitus
-
M.L. Reilly, S.F. Schillie, E. Smith, T. Poissant, C.W. Vonderwahl, K. Gerard, J. Baumgartner, L. Mercedes, K. Sweet, D. Muleta, D.J. Zaccaro, R.M. Klevens, and T.V. Murphy Increased risk of acute hepatitis B among adults with diagnosed diabetes mellitus J. Diabetes Sci. Technol. 6 2012 858 866
-
(2012)
J. Diabetes Sci. Technol.
, vol.6
, pp. 858-866
-
-
Reilly, M.L.1
Schillie, S.F.2
Smith, E.3
Poissant, T.4
Vonderwahl, C.W.5
Gerard, K.6
Baumgartner, J.7
Mercedes, L.8
Sweet, K.9
Muleta, D.10
Zaccaro, D.J.11
Klevens, R.M.12
Murphy, T.V.13
-
115
-
-
20444494440
-
Therapy insight: Influence of type 2 diabetes on the development, treatment and outcomes of cancer
-
L.C. Richardson, and L.A. Pollack Therapy insight: influence of type 2 diabetes on the development, treatment and outcomes of cancer Nat. Clin. Pract. Oncol. 2 2005 48 53
-
(2005)
Nat. Clin. Pract. Oncol.
, vol.2
, pp. 48-53
-
-
Richardson, L.C.1
Pollack, L.A.2
-
118
-
-
84255169908
-
Relationship of type II diabetes and metformin use to ovarian cancer progression, survival, and chemosensitivity
-
I.L. Romero, A. McCormick, K.A. McEwen, S. Park, T. Karrison, S.D. Yamada, S. Pannain, and E. Lengyel Relationship of type II diabetes and metformin use to ovarian cancer progression, survival, and chemosensitivity Obstet. Gynecol. 119 2012 61 67
-
(2012)
Obstet. Gynecol.
, vol.119
, pp. 61-67
-
-
Romero, I.L.1
McCormick, A.2
McEwen, K.A.3
Park, S.4
Karrison, T.5
Yamada, S.D.6
Pannain, S.7
Lengyel, E.8
-
119
-
-
0035832558
-
Excess mortality in a population with diabetes and the impact of material deprivation: Longitudinal, population based study
-
N.A. Roper, R.W. Bilous, W.F. Kelly, N.C. Unwin, and V.M. Connolly Excess mortality in a population with diabetes and the impact of material deprivation: longitudinal, population based study BMJ 322 2001 1389 1393
-
(2001)
BMJ
, vol.322
, pp. 1389-1393
-
-
Roper, N.A.1
Bilous, R.W.2
Kelly, W.F.3
Unwin, N.C.4
Connolly, V.M.5
-
120
-
-
84859076050
-
Lower risk of cancer in patients on metformin in comparison with those on sulfonylurea derivatives: Results from a large population-based follow-up study
-
R. Ruiter, L.E. Visser, M.P. van Herk-Sukel, J.W. Coebergh, H.R. Haak, P.H. Geelhoed-Duijvestijn, S.M. Straus, R.M. Herings, and B.H. Stricker Lower risk of cancer in patients on metformin in comparison with those on sulfonylurea derivatives: results from a large population-based follow-up study Diabetes Care 35 2012 119 124
-
(2012)
Diabetes Care
, vol.35
, pp. 119-124
-
-
Ruiter, R.1
Visser, L.E.2
Van Herk-Sukel, M.P.3
Coebergh, J.W.4
Haak, H.R.5
Geelhoed-Duijvestijn, P.H.6
Straus, S.M.7
Herings, R.M.8
Stricker, B.H.9
-
121
-
-
84861127026
-
Metformin use is associated with better survival of diabetic patients with pancreatic cancer
-
N. Sadeghi, J.L. Abbruzzese, S.C. Yeung, M. Hassan, and D. Li Metformin use is associated with better survival of diabetic patients with pancreatic cancer Clin. Cancer Res. 18 2012 2905 2912
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 2905-2912
-
-
Sadeghi, N.1
Abbruzzese, J.L.2
Yeung, S.C.3
Hassan, M.4
Li, D.5
-
123
-
-
33846874575
-
The role of the IGF system in cancer growth and metastasis: Overview and recent insights
-
A.A. Samani, S. Yakar, D. LeRoith, and P. Brodt The role of the IGF system in cancer growth and metastasis: overview and recent insights Endocrinol. Rev. 28 2007 20 47
-
(2007)
Endocrinol. Rev.
, vol.28
, pp. 20-47
-
-
Samani, A.A.1
Yakar, S.2
Leroith, D.3
Brodt, P.4
-
124
-
-
3142594193
-
The LKB1 tumor suppressor negatively regulates mTOR signaling
-
R.J. Shaw, N. Bardeesy, B.D. Manning, L. Lopez, M. Kosmatka, R.A. DePinho, and L.C. Cantley The LKB1 tumor suppressor negatively regulates mTOR signaling Cancer Cell 6 2004 91 99
-
(2004)
Cancer Cell
, vol.6
, pp. 91-99
-
-
Shaw, R.J.1
Bardeesy, N.2
Manning, B.D.3
Lopez, L.4
Kosmatka, M.5
Depinho, R.A.6
Cantley, L.C.7
-
125
-
-
84860317111
-
Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation
-
A. Sikka, M. Kaur, C. Agarwal, G. Deep, and R. Agarwal Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation Cell Cycle 11 2012 1374 1382
-
(2012)
Cell Cycle
, vol.11
, pp. 1374-1382
-
-
Sikka, A.1
Kaur, M.2
Agarwal, C.3
Deep, G.4
Agarwal, R.5
-
126
-
-
84876418313
-
Metformin use and improved response to therapy in esophageal adenocarcinoma
-
Epub ahead of print
-
H.D. Skinner, M.R. McCurdy, A.E. Echeverria, S.H. Lin, J.W. Welsh, M.S. O'Reilly, W.L. Hofstetter, J.A. Ajani, R. Komaki, J.D. Cox, V.C. Sandulache, J.N. Myers, and T.M. Guerrero Metformin use and improved response to therapy in esophageal adenocarcinoma Acta Oncol. 2012 Epub ahead of print
-
(2012)
Acta Oncol.
-
-
Skinner, H.D.1
McCurdy, M.R.2
Echeverria, A.E.3
Lin, S.H.4
Welsh, J.W.5
O'Reilly, M.S.6
Hofstetter, W.L.7
Ajani, J.A.8
Komaki, R.9
Cox, J.D.10
Sandulache, V.C.11
Myers, J.N.12
Guerrero, T.M.13
-
127
-
-
84869840608
-
The use of metformin and the incidence of lung cancer in patients with type 2 diabetes
-
Epub ahead of print
-
B.B. Smiechowski, L. Azoulay, H. Yin, M.N. Pollak, and S. Suissa The use of metformin and the incidence of lung cancer in patients with type 2 diabetes Diabetes Care 2012 Epub ahead of print
-
(2012)
Diabetes Care
-
-
Smiechowski, B.B.1
Azoulay, L.2
Yin, H.3
Pollak, M.N.4
Suissa, S.5
-
128
-
-
84860196738
-
Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells
-
C.W. Song, H. Lee, R.P. Dings, B. Williams, J. Powers, T.D. Santos, B.H. Choi, and H.J. Park Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells Sci. Rep. 2 2012 362
-
(2012)
Sci. Rep.
, vol.2
, pp. 362
-
-
Song, C.W.1
Lee, H.2
Dings, R.P.3
Williams, B.4
Powers, J.5
Santos, T.D.6
Choi, B.H.7
Park, H.J.8
-
129
-
-
84862848716
-
Cancer risk associated with use of metformin and sulfonylurea in type 2 diabetes: A meta-analysis
-
D. Soranna, L. Scotti, A. Zambon, C. Bosetti, G. Grassi, A. Catapano, C. La Vecchia, G. Mancia, and G. Corrao Cancer risk associated with use of metformin and sulfonylurea in type 2 diabetes: a meta-analysis Oncologist 17 2012 813 822
-
(2012)
Oncologist
, vol.17
, pp. 813-822
-
-
Soranna, D.1
Scotti, L.2
Zambon, A.3
Bosetti, C.4
Grassi, G.5
Catapano, A.6
La Vecchia, C.7
Mancia, G.8
Corrao, G.9
-
130
-
-
84866138849
-
Cancer outcomes and all-cause mortality in adults allocated to metformin: Systematic review and collaborative meta-analysis of randomised clinical trials
-
R.J. Stevens, R. Ali, C.R. Bankhead, M.A. Bethel, B.J. Cairns, R.P. Camisasca, F.L. Crowe, A.J. Farmer, S. Harrison, J.A. Hirst, P. Home, S.E. Kahn, J.H. McLellan, R. Perera, A. Pluddemann, A. Ramachandran, N.W. Roberts, P.W. Rose, A. Schweizer, G. Viberti, and R.R. Holman Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials Diabetologia 55 2012 2593 2603
-
(2012)
Diabetologia
, vol.55
, pp. 2593-2603
-
-
Stevens, R.J.1
Ali, R.2
Bankhead, C.R.3
Bethel, M.A.4
Cairns, B.J.5
Camisasca, R.P.6
Crowe, F.L.7
Farmer, A.J.8
Harrison, S.9
Hirst, J.A.10
Home, P.11
Kahn, S.E.12
McLellan, J.H.13
Perera, R.14
Pluddemann, A.15
Ramachandran, A.16
Roberts, N.W.17
Rose, P.W.18
Schweizer, A.19
Viberti, G.20
Holman, R.R.21
more..
-
131
-
-
85028118271
-
Erratum to: Cancer outcomes and all-cause mortality in adults allocated to metformin: Systematic review and collaborative meta-analysis of randomised clinical trials
-
R.J. Stevens, R. Ali, C.R. Bankhead, M.A. Bethel, B.J. Cairns, R.P. Camisasca, F.L. Crowe, A.J. Farmer, S. Harrison, J.A. Hirst, P. Home, S.E. Kahn, J.H. McLellan, R. Perera, A. Pluddemann, A. Ramachandran, N.W. Roberts, P.W. Rose, A. Schweizer, G. Viberti, and R.R. Holman Erratum to: cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials Diabetologia 55 2012 3399 3400
-
(2012)
Diabetologia
, vol.55
, pp. 3399-3400
-
-
Stevens, R.J.1
Ali, R.2
Bankhead, C.R.3
Bethel, M.A.4
Cairns, B.J.5
Camisasca, R.P.6
Crowe, F.L.7
Farmer, A.J.8
Harrison, S.9
Hirst, J.A.10
Home, P.11
Kahn, S.E.12
McLellan, J.H.13
Perera, R.14
Pluddemann, A.15
Ramachandran, A.16
Roberts, N.W.17
Rose, P.W.18
Schweizer, A.19
Viberti, G.20
Holman, R.R.21
more..
-
132
-
-
84869788946
-
Metformin and the risk of cancer: Time-related biases in observational studies
-
S. Suissa, and L. Azoulay Metformin and the risk of cancer: time-related biases in observational studies Diabetes care 35 2012 2665 2673
-
(2012)
Diabetes Care
, vol.35
, pp. 2665-2673
-
-
Suissa, S.1
Azoulay, L.2
-
133
-
-
79952290187
-
Metformin treatment exerts antiinvasive and antimetastatic effects in human endometrial carcinoma cells
-
B.K. Tan, R. Adya, J. Chen, H. Lehnert, L.J. Sant Cassia, and H.S. Randeva Metformin treatment exerts antiinvasive and antimetastatic effects in human endometrial carcinoma cells J. Clin. Endocrinol. Metab. 96 2011 808 816
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. 808-816
-
-
Tan, B.K.1
Adya, R.2
Chen, J.3
Lehnert, H.4
Sant Cassia, L.J.5
Randeva, H.S.6
-
134
-
-
84865717087
-
Diabetes, metformin use, and colon cancer: A population-based cohort study in Taiwan
-
C.H. Tseng Diabetes, metformin use, and colon cancer: a population-based cohort study in Taiwan Eur. J. Endocrinol. 167 2012 409 416
-
(2012)
Eur. J. Endocrinol.
, vol.167
, pp. 409-416
-
-
Tseng, C.H.1
-
135
-
-
84856698481
-
Glucose-lowering agents and the patterns of risk for cancer: A study with the general practice research database and secondary care data
-
T.P. van Staa, D. Patel, A.M. Gallagher, and M.L. de Bruin Glucose-lowering agents and the patterns of risk for cancer: a study with the general practice research database and secondary care data Diabetologia 55 2012 654 665
-
(2012)
Diabetologia
, vol.55
, pp. 654-665
-
-
Van Staa, T.P.1
Patel, D.2
Gallagher, A.M.3
De Bruin, M.L.4
-
136
-
-
72549116243
-
Diabetes and cancer
-
P. Vigneri, F. Frasca, L. Sciacca, G. Pandini, and R. Vigneri Diabetes and cancer Endocrinol. Relat. Cancer 16 2009 1103 1123
-
(2009)
Endocrinol. Relat. Cancer
, vol.16
, pp. 1103-1123
-
-
Vigneri, P.1
Frasca, F.2
Sciacca, L.3
Pandini, G.4
Vigneri, R.5
-
138
-
-
60749137629
-
PPARgamma-independent antitumor effects of thiazolidinediones
-
S. Wei, J. Yang, S.L. Lee, S.K. Kulp, and C.S. Chen PPARgamma-independent antitumor effects of thiazolidinediones Cancer Lett. 276 2009 119 124
-
(2009)
Cancer Lett.
, vol.276
, pp. 119-124
-
-
Wei, S.1
Yang, J.2
Lee, S.L.3
Kulp, S.K.4
Chen, C.S.5
-
139
-
-
0026011343
-
Reconsideration of inhibitory effect of metformin on intestinal glucose absorption
-
C. Wilcock, and C.J. Bailey Reconsideration of inhibitory effect of metformin on intestinal glucose absorption J. Pharm. Pharmacol. 43 1991 120 121
-
(1991)
J. Pharm. Pharmacol.
, vol.43
, pp. 120-121
-
-
Wilcock, C.1
Bailey, C.J.2
-
140
-
-
33751003491
-
Hypoglycemia in Type 2 diabetic patients randomized to and maintained on monotherapy with diet, sulfonylurea, metformin, or insulin for 6 years from diagnosis: UKPDS73
-
A.D. Wright, C.A. Cull, K.M. Macleod, and R.R. Holman Hypoglycemia in Type 2 diabetic patients randomized to and maintained on monotherapy with diet, sulfonylurea, metformin, or insulin for 6 years from diagnosis: UKPDS73 J. Diabetes Complications 20 2006 395 401
-
(2006)
J. Diabetes Complications
, vol.20
, pp. 395-401
-
-
Wright, A.D.1
Cull, C.A.2
Macleod, K.M.3
Holman, R.R.4
-
141
-
-
70350583054
-
Metformin use and prostate cancer in Caucasian men: Results from a population-based case-control study
-
J.L. Wright, and J.L. Stanford Metformin use and prostate cancer in Caucasian men: results from a population-based case-control study Cancer Causes Control 20 2009 1617 1622
-
(2009)
Cancer Causes Control
, vol.20
, pp. 1617-1622
-
-
Wright, J.L.1
Stanford, J.L.2
-
142
-
-
84857467120
-
Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
-
N. Wu, C. Gu, H. Gu, H. Hu, Y. Han, and Q. Li Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153 Neoplasma 58 2011 482 490
-
(2011)
Neoplasma
, vol.58
, pp. 482-490
-
-
Wu, N.1
Gu, C.2
Gu, H.3
Hu, H.4
Han, Y.5
Li, Q.6
-
143
-
-
77952520262
-
Obesity, hyperinsulinemia and breast cancer: Novel targets and a novel role for metformin
-
P.J. Wysocki, and B. Wierusz-Wysocka Obesity, hyperinsulinemia and breast cancer: novel targets and a novel role for metformin Expert Rev. Mol. Diagn. 10 2010 509 519
-
(2010)
Expert Rev. Mol. Diagn.
, vol.10
, pp. 509-519
-
-
Wysocki, P.J.1
Wierusz-Wysocka, B.2
-
144
-
-
5144234027
-
Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients
-
Y.X. Yang, S. Hennessy, and J.D. Lewis Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients Gastroenterology 127 2004 1044 1050
-
(2004)
Gastroenterology
, vol.127
, pp. 1044-1050
-
-
Yang, Y.X.1
Hennessy, S.2
Lewis, J.D.3
-
145
-
-
33845984333
-
Epidemic obesity and type 2 diabetes in Asia
-
K.H. Yoon, J.H. Lee, J.W. Kim, J.H. Cho, Y.H. Choi, S.H. Ko, P. Zimmet, and H.Y. Son Epidemic obesity and type 2 diabetes in Asia Lancet 368 2006 1681 1688
-
(2006)
Lancet
, vol.368
, pp. 1681-1688
-
-
Yoon, K.H.1
Lee, J.H.2
Kim, J.W.3
Cho, J.H.4
Choi, Y.H.5
Ko, S.H.6
Zimmet, P.7
Son, H.Y.8
-
146
-
-
84858693012
-
Reduced risk of colorectal cancer with metformin therapy in patients with type 2 diabetes: A meta-analysis
-
Z.J. Zhang, Z.J. Zheng, H. Kan, Y. Song, W. Cui, G. Zhao, and K.E. Kip Reduced risk of colorectal cancer with metformin therapy in patients with type 2 diabetes: a meta-analysis Diabetes Care 34 2011 2323 2328
-
(2011)
Diabetes Care
, vol.34
, pp. 2323-2328
-
-
Zhang, Z.J.1
Zheng, Z.J.2
Kan, H.3
Song, Y.4
Cui, W.5
Zhao, G.6
Kip, K.E.7
-
147
-
-
84863601615
-
Metformin for liver cancer prevention in patients with type 2 diabetes: A systematic review and meta-analysis
-
Z.J. Zhang, Z.J. Zheng, R. Shi, Q. Su, Q. Jiang, and K.E. Kip Metformin for liver cancer prevention in patients with type 2 diabetes: a systematic review and meta-analysis J. Clin. Endocrinol. Metab. 97 2012 2347 2353
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
, pp. 2347-2353
-
-
Zhang, Z.J.1
Zheng, Z.J.2
Shi, R.3
Su, Q.4
Jiang, Q.5
Kip, K.E.6
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