Determinants of ligand binding and catalytic activity in the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Raasakka, Arne ^a,b,c   Myllykoski, Matti ^a   Laulumaa, Saara ^a,c,d   Lehtimäki, Mari ^a   Härtlein, Michael ^e   Moulin, Martine ^e   Kursula, Inari ^a,b,c   Kursula, Petri ^a,b,c  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF BERGEN   (Norway)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^d EUROPEAN SPALLATION SOURCE ERIC   (Sweden)

^e INSTITUT LAUE LANGEVIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; LIGAND; PROTEIN BINDING;

ANIMAL; BINDING SITE; BIOCATALYSIS; CHEMISTRY; CIRCULAR DICHROISM; ENZYME ACTIVE SITE; GENETICS; KINETICS; MASS SPECTROMETRY; METABOLISM; MOLECULAR MODEL; MOUSE; MUTATION; MYELIN SHEATH; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; SMALL ANGLE SCATTERING; STATIC ELECTRICITY; TEMPERATURE; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

2',3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE; ANIMALS; BINDING SITES; BIOCATALYSIS; CATALYTIC DOMAIN; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; KINETICS; LIGANDS; MASS SPECTROMETRY; MICE; MODELS, MOLECULAR; MUTATION; MYELIN SHEATH; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; SCATTERING, SMALL ANGLE; STATIC ELECTRICITY; TEMPERATURE; X-RAY DIFFRACTION;

EID: 84946925527     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep16520     Document Type: Article

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