Subcortical oligodendrocyte- and astrocyte-associated gene expression in subjects with schizophrenia, major depression and bipolar disorder

Schizophrenia Research

Volumn 112, Issue 1-3, 2009, Pages 54-64

  Barley, Kevin ^a,b   Dracheva, Stella ^a,b   Byne, William ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Anterior nucleus; Bipolar disorder; Internal capsule; Major depression; Mediodorsal nucleus; Myelin; Oligodendrocyte; Putamen; Schizophrenia; Thalamus

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; ALDEHYDE DEHYDROGENASE; GALACTOSYLCERAMIDASE; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA; MYELIN; MYELIN ASSOCIATED GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN;

ADULT; AGE; ARTICLE; ASTROCYTE; BIPOLAR DISORDER; BRAIN CORTEX; CAPSULA INTERNA; CELL FATE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MAJOR DEPRESSION; MALE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; OLIGODENDROGLIA; PRIORITY JOURNAL; PUTAMEN; REAL TIME POLYMERASE CHAIN REACTION; SCHIZOPHRENIA; STATISTICAL SIGNIFICANCE; THALAMUS DORSOMEDIAL NUCLEUS; THALAMUS NUCLEUS;

ADULT; ALDEHYDE DEHYDROGENASE; ANALYSIS OF VARIANCE; ASTROCYTES; BIPOLAR DISORDER; BRAIN; DEPRESSIVE DISORDER, MAJOR; FEMALE; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; ISOENZYMES; MALE; MIDDLE AGED; OLIGODENDROGLIA; RNA, MESSENGER; SCHIZOPHRENIA; SEX FACTORS;

EID: 67349178848     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2009.04.019     Document Type: Article

References (61)

1. Ardekani B.A., Nierenberg J., Hoptman M.J., Javitt D.C., and Lim K.O. MRI study of white matter diffusion anisotropy in schizophrenia. Neuroreport 14 (2003) 2025-2029
2. Anderson C.M., and Swanson R.A. Astrocyte glutamate transport: review of properties, regulation, and physiological functions. Glia 32 (2000) 1-14
3. Aston C., Jiang L., and Sokolov B.P. Microarray analysis of postmortem temporal cortex from patients with schizophrenia. J. Neurosci. Res. 77 (2004) 858-866
4. Aston C., Jiang L., and Sokolov B.P. Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the temporal cortex from patients with major depressive disorder. Mol. Psychiatry 10 (2005) 309-322
5. Awatramani R., Scherer S., Grinspan J., Collarini E., Skoff R., O'Hagan D., Garbern J., and Kamholz J. Evidence that the homeodomain protein Gtx is involved in the regulation of oligodendrocyte myelination. J. Neurosci. 17 (1997) 6657-6668
6. Ballmaier M., Schlagenhauf F., Toga A.W., Gallinat J., Koslowski M., Zoli M., Hojatkashani C., Narr K.L., and Heinz A. Regional patterns and clinical correlates of basal ganglia morphology in non-medicated schizophrenia. Schizophr. Res. 106 (2008) 140-147
7. Buchsbaum M.S., Tang C.Y., Peled S., Gudbjartsson H., Lu D., Hazlett E.A., Downhill J., Haznedar M., Fallon J.H., and Atlas S.W. MRI white matter diffusion anisotropy and PET metabolic rate in schizophrenia. Neuroreport 9 (1998) 425-430
8. Buchsbaum M.S., Buchsbaum B.R., Hazlett E.A., Haznedar M.M., Newmark R., Tang C.Y., and Hof P.R. Relative glucose metabolic rate higher in white matter in patients with schizophrenia. Am. J. Psychiatry 164 (2007) 1072-1081
9. Byne W., Kidkardnee S., Tatusov A., Yiannoulos G., Buchsbaum M.S., and Haroutunian V. Schizophrenia-associated reduction of neuronal and oligodendrocyte numbers in the anterior principal thalamic nucleus. Schizophr. Res. 85 (2006) 245-253
10. Byne W., Tatusov A., Yiannoulos G., Vong G.S., and Marcus S. Effects of mental illness and aging in two thalamic nuclei. Schizophr. Res. 106 (2008) 172-181
11. Byne W., Hazlett E.A., Buchsbaum M.S., and Kemether E. The thalamus and schizophrenia: current status of research. Acta Neuropathol. 117 (2009) 347-368
12. Cahoy J.D., Emery B., Kaushal A., Foo L.C., Zamanian J.L., Christopherson K.S., Xing Y., Lubischer J.L., Krieg P.A., Krupenko S.A., Thompson W.J., and Barres B.A. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J. Neurosci. 28 (2008) 264-278
13. Casanova M.F. Astrocytosis and schizophrenia. Schizophr. Res. 5 (1991) 186-187
14. Cheung V., Cheung C., McAlonan G.M., Deng Y., Wong J.G., Yip L., Tai K.S., Khong P.L., Sham P., and Chua S.E. A diffusion tensor imaging study of structural dysconnectivity in never-medicated, first-episode schizophrenia. Psychol. Med. 38 (2008) 877-885
15. de Vellis J., and Carpenter E. Development. In: Siegel G.J., Albers R.W., and Brady S.T.P.D.L. (Eds). Basic Neurochemistry (2006), Elsevier, Amsterdam 437-458
16. Dracheva S., Davis K.L., Chin B., Woo D.A., Schmeidler J., and Haroutunian V. Myelin-associated mRNA and protein expression deficits in the anterior cingulate cortex and hippocampus in elderly schizophrenia patients. Neurobiol. Dis. 21 (2006) 531-540
17. Hakak Y., Walker J.R., Li C., Wong W.H., Davis K.L., Buxbaum J.D., Haroutunian V., and Fienberg A.A. Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 4746-4751
18. Haroutunian V., Katsel P., Dracheva S., and Davis K.L. The human homolog of the QKI gene affected in the severe dysmyelination "quaking" mouse phenotype: downregulated in multiple brain regions in schizophrenia. Am. J. Psychiatry 163 (2006) 1834-1837
19. Haroutunian V., Katsel P., Dracheva S., Stewart D.G., and Davis K.L. Variations in oligodendrocyte-related gene expression across multiple cortical regions: implications for the pathophysiology of schizophrenia. Int. J. Neuropsychopharmacol. 10 (2007) 565-573
20. Hof P.R., Haroutunian V., Friedrich Jr. V.L., Byne W., Buitron C., Perl D.P., and Davis K.L. Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia. Biol. Psychiatry 53 (2003) 1075-1085
21. Kanaan R.A., Kim J.S., Kaufmann W.E., Pearlson G.D., Barker G.J., and McGuire P.K. Diffusion tensor imaging in schizophrenia. Biol. Psychiatry 58 (2005) 921-929
22. Katsel P., Davis K.L., Li C., Tan W., Greenstein E., Kleiner Hoffman L.B., and Haroutunian V. Abnormal indices of cell cycle activity in schizophrenia and their potential association with oligodendrocytes. Neuropsychopharmacology 33 (2008) 2993-3009
23. Keirstead H.S., and Blakemore W.F. Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord. J. Neuropathol. Exp. Neurol. 56 (1997) 1191-1201
24. Konopaske G.T., Dorph-Petersen K.A., Sweet R.A., Pierri J.N., Zhang W., Sampson A.R., and Lewis D.A. Effect of chronic antipsychotic exposure on astrocyte and oligodendrocyte numbers in macaque monkeys. Biol. Psychiatry 63 (2008) 759-765
25. Kreczmanski P., Heinsen H., Mantua V., Woltersdorf F., Masson T., Ulfig N., Schmidt-Kastner R., Korr H., Steinbusch H.W., Hof P.R., and Schmitz C. Volume, neuron density and total neuron number in five subcortical regions in schizophrenia. Brain 130 (2007) 678-692
26. Kubicki M., McCarley R.W., and Shenton M.E. Evidence for white matter abnormalities in schizophrenia. Curr. Opin. Psychiatry 18 (2005) 121-134
27. Lasiene J., Sawa Y., Matsui A., and Horner P.J. Increased oligodendrogenesis and myelinogenesis in the aging rodent spinal cord. Soc. Neurosci. Abst. 592 (2007) 11
28. Lee J., Wu Y., Qi Y., Xue H., Liu Y., Scheel D., German M., Qiu M., Guillemot F., Rao M., and Gradwohl G. Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord. Dev. Biol. 253 (2003) 84-98
29. Loerch P.M., Lu T., Dakin K.A., Vann J.M., Isaacs A., Geula C., Wang J., Pan Y., Gabuzda D.H., Li C., Prolla T.A., and Yankner B.A. Evolution of the aging brain transcriptome and synaptic regulation. PLoS ONE 3 (2008) e3329
30. Magistretti P.J., and Pellerin L. The contribution of astrocytes to the 18F-2-deoxyglucose signal in PET activation studies. Mol. Psychiatry 1 (1996) 445-452
31. Malaspina D., Harkavy-Friedman J., Corcoran C., Mujica-Parodi L., Printz D., Gorman J.M., and Van Heertum R. Resting neural activity distinguishes subgroups of schizophrenia patients. Biol. Psychiatry 56 (2004) 931-937
32. McCullumsmith R.E., Gupta D., Beneyto M., Kreger E., Haroutunian V., Davis K.L., and Meador-Woodruff J.H. Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophrenia. Schizophr. Res. 90 (2007) 15-27
33. Mega M.S., and Cummings J.L. Frontal-subcortical circuits and neuropsychiatric disorders. J. Neuropsychiatry Clin. Neurosci. 6 (1994) 358-370
34. Mitkus S.N., Hyde T.M., Vakkalanka R., Kolachana B., Weinberger D.R., Kleinman J.E., and Lipska B.K. Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia. Schizophr. Res. 98 (2008) 129-138
35. Nanitsos E.K., Nguyen K.T., St'astny F., and Balcar V.J. Glutamatergic hypothesis of schizophrenia: involvement of Na+/K+-dependent glutamate transport. J. Biomed. Sci. 12 (2005) 975-984
36. Narayan S., Kass K.E., and Thomas E.A. Chronic haloperidol treatment results in a decrease in the expression of myelin/oligodendrocyte-related genes in the mouse brain. J. Neurosci. Res. 85 (2007) 757-765
37. Neymeyer V., Tephly T.R., and Miller M.W. Folate and 10-formyltetrahydrofolate dehydrogenase (FDH) expression in the central nervous system of the mature rat. Brain Res. 766 (1997) 195-204
38. Nicolay D.J., Doucette J.R., and Nazarali A.J. Transcriptional control of oligodendrogenesis. Glia 55 (2007) 1287-1299
39. Nishiyama A., Komitova M., Suzuki R., and Zhu X. Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity. Nat. Rev., Neurosci. 10 (2009) 9-22
40. Olsen M.L., and Sontheimer H. Functional implications for Kir4.1 channels in glial biology: from K+ buffering to cell differentiation. J. Neurochem. 107 (2008) 589-601
41. Osterhout D.J., Wolven A., Wolf R.M., Resh M.D., and Chao M.V. Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase. J. Cell Biol. 145 (1999) 1209-1218
42. Paez P.M., Garcia C.I., Soto E.F., and Pasquini J.M. Apotransferrin decreases the response of oligodendrocyte progenitors to PDGF and inhibits the progression of the cell cycle. Neurochem. Int. 49 (2006) 359-371
43. Peters A. The effects of normal aging on myelin and nerve fibers: a review. J. Neurocytol. 31 (2002) 581-593
44. Peters A., and Sethares C. Oligodendrocytes, their progenitors and other neuroglial cells in the aging primate cerebral cortex. Cereb. Cortex 14 (2004) 995-1007
45. Shi J., Marinovich A., and Barres B.A. Purification and characterization of adult oligodendrocyte precursor cells from the rat optic nerve. J. Neurosci. 18 (1998) 4627-4636
46. Smith R.E., Haroutunian V., Davis K.L., and Meador-Woodruff J.H. Expression of excitatory amino acid transporter transcripts in the thalamus of subjects with schizophrenia. Am. J. Psychiatry 158 (2001) 1393-1399
47. Steiner J., Bernstein H.G., Bielau H., Farkas N., Winter J., Dobrowolny H., Brisch R., Gos T., Mawrin C., Myint A.M., and Bogerts B. S100B-immunopositive glia is elevated in paranoid as compared to residual schizophrenia: a morphometric study. J. Psychiatr. Res. 42 (2008) 868-876
48. Swanson L.W., and Cowan W.M. An autoradiographic study of the organization of the efferent connections of the hippocampal formation in the rat. J. Comp. Neurol. 172 (1977) 49-84
49. Tkachev D., Mimmack M.L., Ryan M.M., Wayland M., Freeman T., Jones P.B., Starkey M., Webster M.J., Yolken R.H., and Bahn S. Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet 362 (2003) 798-805
50. Torrey E.F., Webster M., Knable M., Johnston N., and Yolken R.H. The Stanley Foundation brain collection and neuropathology consortium. Schizophr. Res. 44 (2000) 151-155
51. Uranova N., Orlovskaya D., Vikhreva O., Zimina I., Kolomeets N., Vostrikov V., and Rachmanova V. Electron microscopy of oligodendroglia in severe mental illness. Brain Res. Bull. 55 (2001) 597-610
52. Uranova N.A., Vostrikov V.M., Orlovskaya D.D., and Rachmanova V.I. Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: a study from the Stanley Neuropathology Consortium. Schizophr. Res. 67 (2004) 269-275
53. van Beveren N.J., van der Spelt J.J., de Haan L., and Fekkes D. Schizophrenia-associated neural growth factors in peripheral blood. A review. Eur. Neuropsychopharmacol. 16 (2006) 469-480
54. van Groen T., Kadish I., and Wyss J.M. Efferent connections of the anteromedial nucleus of the thalamus of the rat. Brain Res. Brain Res. Rev. 30 (1999) 1-26
55. Vogt B.A., Pandya D.N., and Rosene D.L. Cingulate cortex of the rhesus monkey: I. Cytoarchitecture and thalamic afferents. J. Comp. Neurol. 262 (1987) 256-270
56. Wegner M. Expression of transcription factors during oligodendroglial development. Microsc. Res. Tech. 52 (2001) 746-752
57. Weis S., and Llenos I.C. GFAP-immunopositive astrocytes in schizophrenia. Schizophr. Res. 67 (2004) 293-295
58. Xiao L., Xu H., Zhang Y., Wei Z., He J., Jiang W., Li X., Dyck L.E., Devon R.M., Deng Y., and Li X.M. Quetiapine facilitates oligodendrocyte development and prevents mice from myelin breakdown and behavioral changes. Mol. Psychiatry 13 (2008) 697-708
59. Yoshihara Y., Sugihara G., Matsumoto H., Suckling J., Nishimura K., Toyoda T., Isoda H., Tsuchiya K.J., Takebayashi K., Suzuki K., Sakahara H., Nakamura K., Mori N., and Takei N. Voxel-based structural magnetic resonance imaging (MRI) study of patients with early onset schizophrenia. Ann. Gen. Psychiatry 7 (2008) 25
60. Young K.A., Manaye K.F., Liang C.L., Hicks P.B., and German D.C. Reduced number of mediodorsal and anterior thalamic neurons in schizophrenia. Biol. Psychiatry 47 (2000) 944-953
61. Zhu X., Hill R.A., and Nishiyama A. NG2 cells generate oligodendrocytes and gray matter astrocytes in the spinal cord. Neuron Glia Biol. (2008) 1-8