CNP2 mRNA directs synthesis of both CNP1 and CNP2 polypeptides

Journal of Neuroscience Research

Volumn 50, Issue 2, 1997, Pages 248-257

  O'Neill, Ryan C ^a   Minuk, Jeffrey ^a   Cox, Martha E ^a   Braun, Peter E ^a   Gravel, Michel ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

2',3' cyclic nucleotide 3' phosphodiesterase; Bifunctional mRNA; Myelin; Translation initiation

Indexed keywords

CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; MESSENGER RNA;

ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CODON; EXON; GENE MUTATION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PEPTIDE SYNTHESIS; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RIBOSOME; TRANSLATION INITIATION;

EID: 0030737429     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19971015)50:2<248::AID-JNR13>3.0.CO;2-4     Document Type: Article

References (42)

1. Acland P, Dixon M, Peters G, Dickson C (1990): Subcellular fate of the Int-2 oncoprotein is determined by choice of initiation codon. Nature 343:662-665.
2. Bernier L, Alvarez F, Norgard EM, Raible DW, Mentaberry A, Schembri JG, Sabatini DD, Colman DR (1987): Molecular cloning of a 2′,3′-cyclic nucleotide 3′-phosphodiesterase: mRNAs with different 5′ends encode the same set of proteins in nervous and lymphoid tissues. J Neurosci 7:2703-2710.
3. Boeck R, Kolakofsky D (1994): Positions +5 and +6 can be major determinants of the efficiency of non-AUG initiation codons for protein synthesis. EMBO J 13:3608-3617.
4. Boyd L, Thummel CS (1993): Selection of CUG and AUG initiator codons for Drosophila E74A translation depends on down-stream sequences. Proc Natl Acad Sci USA 90:9164-9167.
5. De Angelis DA, Braun PE (1994): Isoprenylation of brain 2′,3′-cyclic nucleotide 3′-phosphodiesterase modulates cell morphology. J Neurosci Res 39:386-397.
6. De Angelis DA, Braun PE (1996a): Binding of 2′, 3′-cyclic nucleotide 3′-phosphodiesterase to myelin: An in vitro study. J Neurochem 66:6:2523-2531.
7. De Angelis DA, Braun PE (1996b): 2′,3′-cyclic nucleotide 3′-phosphodiesterase binds to actin-based cytoskeletal elements in an isoprenylation-independent manner. J Neurochem 67:3:943-951.
8. De Angelis D, Cox M, Gao E, Braun PE (1994): Cellular and molecular characteristics of CNP suggest regulatory mechanisms in myelinogenesis. In Salvati S (ed): "A Multidisciplinary Approach to Myelin Diseases II." New York: Plenum Press, pp 49-58.
9. Delmas P, Laoide BM, Masquilier D, De Groot RP, Foulkes NS, Sassone-Corsi P (1992): Alternative usage of initiation codons in mRNA encoding the cAMP-responsive-element modulator generates regulators with opposite functions. Proc Natl Acad Sci USA 89:4226-4230.
10. Descombes P, Schibler U (1991): A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell 67:569-579.
11. Douglas AJ, Thompson RJ (1993): Structure of the myelin membrane enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase: Evidence for two human mRNAs. Biochem Soc Trans 21:295-297.
12. Douglas AJ, Fox MF, Abbott CM, Hinks LJ, Sharpe G, Povey S, Thompson RJ (1992): Structure and chromosomal localization of the human 2′,3′-cyclic nucleotide 3′-phosphodiesterase gene. Ann Hum Genet 56:243-254.
13. Galland F, Stefanova M, Pirisi V, Birnbaum D (1990): Characterization of a murine glyceraldehyde-3-phosphate dehydrogenase pseudogene. Biochimie 72:759-762.
14. Geballe AP (1996): Translational control mediated by upstream AUG codons. In Hershey JWB, Mathews MB, Sonenberg N (eds): "Translational Control." Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp 173-197.
15. Gravel M, De Angelis DA, Braun PE (1994): Molecular cloning and characterization of 2′,3′-cyclic nucleotide 3′-phosphodiesterase isoform 2. J Neurosci Res 38:243-247.
16. Gravel M, Peterson J, Yong VW, Kottis V, Trapp B, Braun PE (1996): Overexpression of 2′,3′-cyclic nucleotide 3′-phosphodiesterase in transgenic mice alters oligodendrocyte development and produces aberrant myelination. Molec Cell Neurosci 7:453-466.
17. Gravel M, Trapp B, Peterson J, Braun PE (1997): CNP in myelination: Overexpression alters oligodendrocyte morphogenesis. In Juurlink BHJ, Devon RM, Doucette R, Nazarali AJ, Schreyer DJ (eds): "Cell Biology and Pathology of Myelin." New York: Plenum Press, pp 75-82.
18. Hellen CUT, Wimmer E (1995): Translation of encephalomyocarditis virus RNA by internal ribosome entry. Curr Top Microbiol Immunol 203:31-63.
19. Iizuka N, Chen C, Yang Q, Johannes G, Sarnow P (1995): Cap-independent translation and internal initiation of translation in eukaryotic cellular mRNA molecules. Curr Top Microbiol Immunol 203:155-177.
20. Kozak M (1989): The scanning model for translation: An update. J Cell Biol 108:229-241.
21. Kozak M (1990): Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomes. Proc Natl Acad Sci USA 87:8301-8305.
22. Kozak M (1991): An analysis of vertebrate mRNA sequences: Intimations of translational control. J Cell Biol 115:887-903.
23. Kozak M (1995): Adherence to the first-AUG rule when a second AUG codon follows closely upon the first. Proc Natl Acad Sci USA 92:2662-2666.
24. Kurihara T, Monoh K, Sakimura K, Takahashi Y (1990): Alternative splicing of mouse brain 2′,3′-cyclic nucleotide 3′-phosphodiesterase mRNA. Biochem Biophys Res Commun 170:1074-1081.
25. Lin F, MacDougald OA, Diehl AM, Lane MD (1993): A 30-kDa alternative translation product of the CCAAT/enhancer binding protein α message: Transcriptional activator lacking antimitotic activity. Proc Natl Acad Sci USA 90:9606-9610.
26. Lock P, Ralph S, Stanley E, Boulet I, Ramsay R, Dunn AR (1991): Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization. Mol Cell Biol 11:4363-4370.
27. Monoh K, Kurihara T, Sakimura K, Takahashi Y (1989): Structure of mouse 2′,3′-cyclic nucleotide 3′-phosphodiesterase gene. Biochem Biophys Res Comm 165:1213-1220.
28. Monoh K, Kurihara T, Takahashi T, Ichikawa Y, Kumanishi T, Hayashi S, Minoshima S, Shimizu N (1993): Structure, expression and chromosomal localization of the gene encoding human 2′,3′-cyclic nucleotide 3′-phosphodiesterase. Gene 129:297-301.
29. Okayama H, Chen C (1991): Calcium phosphate mediated gene transfer into established cell lines. In Murray EJ (ed): "Methods in Molecular Biology, Vol. 7: Gene Transfer and Expression Protocols." Clifton, NJ: Humana Press, pp 15-21.
30. Peabody DS (1989): Translation initiation at non-AUG triplets in mammalian cells. J Biol Chem 264:5031-5035.
31. Scherer SS, Braun PE, Grinspan J, Collarini E, Wang DY, Kamholz J (1994): Differential regulation of the 2′,3′-cyclic nucleotide 3′-phosphodiesterase gene during oligodendrocyte develop′ ment. Neuron 12:1363-1375.
32. Sedman SA, Gelembiuk GW, Mertz JE (1990): Translation initiation at a downstream AUG occurs with increased efficiency when the upstream AUG is located very close to the 5′ cap. J Virol 64:453-457.
33. Soldati T, Schafer BW, Perriard J-C (1990): Alternative ribosomal initiation gives rise to chicken brain-type creatine kinase isoproteins with heterogeneous amino termini. J Biol Chem 265:8:4498-4506.
34. Spence AM, Sheppard PC, Davie JR, Matuo Y, Nishi N, McKeehan WL, Dodd JG, Matusik RJ (1989): Regulation of a bifunctional mRNA results in synthesis of secreted and nuclear probasin. Proc Natl Acad Sci USA 86:7843-7847.
35. Sprinkle TJ (1989): 2′,3′-cyclic nucleotide 3′-phosphodiesterase, an oligodendrocyte-Schwann cell and myelin associated enzyme of the nervous system. CRC Crit Rev Neurobiol 4:235-300.
36. Staugaitis SM, Bernier L, Smith PR, Colman DR (1990): Expression of the oligodendrocyte marker 2′,3′-cyclic nucleotide 3′-phosphodiesterase in non-glial cells. J Neurosci Res 25:556-560.
37. Tenhunen J, Ulmanen I (1993): Production of rat soluble and membrane-bound catechol O-methyltransferase forms from bifunctional mRNAs. Biochem J 296:595-600.
38. Tsukada Y, Kurihara T (1992): 2′,3′-cyclic nucleotide 3′-phosphodiesterase: Molecular characterization and possible functional significance. In Martenson RE (ed): "Myelin: Biology and Chemistry." Boca Raton: CRC Press, pp 449-180.
39. van Duijn LP, Holsappel S, Kasperaitis M, Bunschoten H, Konings D, Voorma HO (1988): Secondary structure and expression in vivo and in vitro of messenger RNAs into which upstream AUG codons have been inserted. Eur J Biochem 172:59-66.
40. Verity AN, Bredesen D, Vonderscher C, Handley VW, Campagnoni AT (1993): Expression of myelin protein genes and other myelin components in an oligodendrocytic cell line conditionally immortalized with a temperature-sensitive retrovirus. J Neurochem 60:577-587.
41. Vogel US, Thompson RJ (1988): Molecular structure, localization and possible functions of the myelin associated enzyme 2′,3′-cyclic nucleotide phosphodiesterase. J Neurochem 50:1667-1677.
42. Weissbarth S, Maker HS, Raes I, Brannan TS, Lapin EP, Lehrer GM (1981): The activity of 2′,3′-cyclic nucleotide 3′-phosphodiesterase in rat tissues. J Neurochem 37:677-680.