Structural insights into the assembly of the adeno-associated virus type 2 Rep68 protein on the integration site AAVS1

Journal of Biological Chemistry

Volumn 290, Issue 46, 2015, Pages 27487-27499

  Musayev, Faik N ^a   Zarate Perez, Francisco ^a   Bishop, Clayton ^a   Burgner, John W ^a   Escalante, Carlos R ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINS; DNA; INTEGRATION; PROTEINS;

ADENO-ASSOCIATED VIRUS; ADENO-ASSOCIATED VIRUS TYPE 2; BINDING DOMAIN; COMPLEX ASSEMBLY; HUMAN GENOMES; NON-STRUCTURAL; STRUCTURAL INSIGHTS; X-RAY STRUCTURE;

VIRUSES;

GLYCINE; HELICASE; REP68 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; DNA BINDING PROTEIN; REP PROTEINS, ADENO-ASSOCIATED VIRUS 2; VIRAL PROTEIN; VIRUS DNA;

ADENO ASSOCIATED VIRUS 2; ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CHROMOSOME 19; COMPLEX FORMATION; CONTROLLED STUDY; MOLECULAR DOCKING; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; VIRUS DNA CELL DNA INTERACTION; X RAY ANALYSIS; CHEMISTRY; DEPENDOPARVOVIRUS; HUMAN; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DEPENDOVIRUS; DNA, VIRAL; DNA-BINDING PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; VIRAL PROTEINS; VIRUS INTEGRATION;

EID: 84946923297     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.669960     Document Type: Article

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