Structural Studies of AAV2 Rep68 Reveal a Partially Structured Linker and Compact Domain Conformation

Biochemistry

Volumn 54, Issue 38, 2015, Pages 5907-5919

  Musayev, Faik N ^a   Zarate Perez, Francisco ^a   Bardelli, Martino ^b   Bishop, Clayton ^a   Saniev, Emil F ^a   Linden, R Michael ^b,c   Henckaerts, Els ^b   Escalante, Carlos R ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LIFE CYCLE; OLIGOMERIZATION; OLIGOMERS; PROTEINS; VIRUSES;

ADENO-ASSOCIATED VIRUS; COMPACT ARRANGEMENTS; FULL-LENGTH PROTEINS; MULTIFUNCTIONAL DOMAINS; NONSTRUCTURAL PROTEINS; RIGID BODY MODELS; SOLUTION STRUCTURES; STRUCTURAL STUDIES;

X RAY SCATTERING;

HELICASE; PROLINE; REP68 PROTEIN; REP78 PROTEIN; SF3 HELICASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; DNA BINDING PROTEIN; REP PROTEINS, ADENO-ASSOCIATED VIRUS 2; VIRAL PROTEIN;

ADENO ASSOCIATED VIRUS 2; ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; CRYSTALLIZATION; MOLECULAR MODEL; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PURIFICATION; VIROGENESIS; X RAY CRYSTALLOGRAPHY; CHEMISTRY; DEPENDOPARVOVIRUS; HUMAN; PARVOVIRUS INFECTION; PROTEIN TERTIARY STRUCTURE; SMALL ANGLE SCATTERING; VIROLOGY; X RAY DIFFRACTION;

CRYSTALLOGRAPHY, X-RAY; DEPENDOVIRUS; DNA-BINDING PROTEINS; HUMANS; MODELS, MOLECULAR; PARVOVIRIDAE INFECTIONS; PROTEIN STRUCTURE, TERTIARY; SCATTERING, SMALL ANGLE; VIRAL PROTEINS; X-RAY DIFFRACTION;

EID: 84942595385     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00610     Document Type: Article

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